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이승준,신인동,최수창,김용우,이종렬,이득우,Lee, Seung-Jun,Shin, In-Dong,Cha, Sao-Chang,Kim, Yong-Woo,Lee, Jong-Ryul,Lee, Deug-Woo 한국생산제조학회 2010 한국생산제조학회지 Vol.10 No.6
The development of high-speed spindle have been studied extensively for micro machining in advanced industrial countries. The research of miniaturized high-speed air spindle is important part which needs for the micro machining process of high quality. So, This study was to carry out results about design characteristics of miniaturized high-speed air spindle. We had designed 4type turbines and shaft. They were simulated in use the computer simulation programs. We made them as products. They measured RPM (revolutions per minute). As a result of experiments, there was a contrast among 4type Turbines. it reached 384,000rpm in 4.5bar of air pressure. And, We tried to compare the results of measurement whit the results of computer simulation.
소아안신탕(小兒安神湯)이 STRESS를 유발한 흰쥐의 적출심장(摘出心臟)에 미치는 영향
이승준,이진용,김덕곤,Lee Seung-Jun,Lee Jin-Yong,Kim Deok-Gon 대한한방소아과학회 2000 대한한방소아과학회지 Vol.14 No.2
It has long been known that SOAT is effective for sudden palpitation occurring unexpectedly in Oriental Medicine. However, effect of SOAT on the isolated heart has not been studied yet. The purpose of this study is to investigate the effect of SOAT on hemodynamics and ECG of isolated rat hearts induced by electrical stimulation using Langendorff perfusion apparatus for nonworking heart. SOAT extract was manufactured by water-alcohol precipitated method. Sprague-Dawley rats weighting $120{\sim}150g$ were used for the experiments, Subject animals were divided into four groups, which are consisted of 1) control(Group orally administered by normal saline 1ml for 14days), 2) sample A(Group orally administered by SOAT extract 1ml for 14days), 3) sample C(Group injected by SOAT extract 0.5ml after stimulation, 4) sample C(Group injected by SOAT extract 1ml after stimulation. To evluate the effects of SOAT on hemodynamics and ECG of isolated rat heart induced by stimulation, heart rate, left ventricular pressure, systolic power, diastolic power, coronary artery perfusion volume and ECG were measured using Langendorff apparatus in both stimulation mode(5 volts, 450 beats/min) and arrythmic mode(5 volts, 420 beats/min including 60 beats/min) The results obtained are as follows : 1. After receiving stressful electrical stimuli, isolated heart showed the heart rate, left ventricular pressure, systolic power, diastolic power, coronary artery perfusion volume were all decreased temporarily, but perfusion continued longer recovery to the control state appeared. However, the coronary artery perfusion volume diminished continuously. 2. The heart rates did not change significantly with both stimulation mode and arrhythmic mode, among experimental groups. 3. The left ventricular pressure showed with both stimulation mode and arrhythmic mode, the significant changes(p<0.05) especially in the injection sample group. In case of stimulation mode, low concentration injection group(0.5ml) was more significantly increased rather than high concentration group(1ml) and in case of arrhythmic mode, high density group(1ml) was so increased than the other(0.5ml). 4. For the systolic power and diastolic power, no significant changes were noticed in the stimulation mode, but in the arrhythmic mode of injection sample groups, significant change(p<0.05) was noticed in both systolic power and diastolic power. Specially the high concentration group(1ml) showed more significant increase than the low concentration group. 5. For the coronary artery perfusion volume, no significant change difference among sample groups was observed in both the stimulation mode and the arrhythmic mode. 6. For the ECG recordings, arrhythmia was induced by electrical stimulus of arrythmia mode and after the stimulus was removed, irregular wave appeared temporarily, but as perpusion continued, recovery to the control state was abtained like the stimulation mode. According to the above results, SOAT significantly changed the hemodynamic data from the electrically stressed, isolated hearts of connected Langendorff perfusion apparatus and we propose SOAT has the direct effects on the muscular function of heart.
이승준,Seung Jun Lee,M,D 대한안과학회 2007 대한안과학회지 Vol.48 No.8
Purpose: To report a rare case of bilateral pseudotumor with a two-week rapid spontaneous regression Method: A 63-year-old man visited our clinic with a chief complaint of a headache and right ocular pain. An orbital computerized tomography (CT) scan revealed a roud mass with well-demarcated capsule-like boundaries located in the inferior part of both orbits. After a systemic evaluation to exclude a systemic malignancy, we performed excisional biopsy of the right orbital mass to make diagnosis. Result: The right orbital mass was not found at the time of surgery for an excisional biopsy. Instead, we took multiple small biopsies of orbital fat, inferior rectus muscle, and adjacent soft tissues. Histologic examination revealed a non-specific inflammatory reaction without the presence of tumor cells. There was a marked spontaneous regression of the mass in both orbits on an immediate follow-up orbital CT. The patient began steroid treatment for 12 weeks under the presumptive diagnosis of bilateral pseudotumor. There was no evidence of recurrence at the eight-month follow-up.
저 악성도 연골육종으로 악성 변화한 섬유성 이형성증으로 오진하여 치료방침의 오류가 발생한 연골 모세포형 골육종 - 증례 보고 -
이승준,고재수,원호현,전대근,Lee, Seung-Jun,Koh, Jae-Soo,Won, Ho-Hyun,Jeon, Dae-Geun 대한근골격종양학회 2008 대한골관절종양학회지 Vol.14 No.1
Malignant degeneration of fibrous dysplasia is rare and involves transformation into osteosarcoma, fibrosarcoma and chondrosarcoma. The most frequent sites involved in malignant transformation were craniofacial bones, proximal femur, humerus, pelvis, tibia and scapula in a decreasing order of frequency. An 41-year-old man with a history of polyostotic fibrous dysplasia presented with increasing left arm pain. Plain radiograph showed expansile destructive lesion along the humeral shaft. As initial biopsy report was low grade chondrosarcoma, he underwent marginal resection. However, he developed local recurrence 7 month later and subsequent pathologic finding was chondroblastic osteosarcoma. We report one case of secondary chondroblastic osteosarcoma from polyostotic fibrous dysplasia initially misdiagnosed as low grade chondrosarcoma that caused fallacy in treatment strategy. 섬유성 골 이형성증이 골육종, 연골육종, 섬유육종 등으로 악성 변환을 하는 것은 매우 드무나 잘 알려져 있다. 악성 변화가 흔히 일어나는 부위는 두경부, 근위 대퇴골, 상완골, 골반골, 경골, 및 견갑골 순이다. 41세 다발성 섬유성 이형성증 환자가 상완골의 동통을 주소로 내원하였다. 방사선 상 상완골 간부의 골 팽윤 및 파괴를 보였다. 생검 상 저악성도의 연골육종으로 진단하여 변연부 절제를 하였으나 7개월 만에 근위부에서 국소 재발 후 재 절제한 표본은 연골아세포형 골육종으로 진단하였다. 다발성 섬유성 이형성증에서 속발한 연골아세포형 골육종을 저악성도 연골육종으로 오진하여 치료방침에 오류가 있었던 1례를 문헌고찰과 함께 보고하는 바이다.
기획특집2 - 초정밀 광학부품 기술 동향 -Polymer and Hybrid Optics
이승준,Lee, Seung-Jun 한국광학기기산업협회 2011 光學世界 Vol.135 No.-
광학 속성을 가진 폴리머 소재는 새롭고 정교한 전자광학 장치를 가능하게 해주고, 커머셜 마켓과 의학 용품, 바코드 인식, 보안과 지문 추출기, 동작 인식 센서, CCD 카메라 및 레이저 collimation 장치들을 가능하게 한다. 현재의 발전된 폴리머 기술과 인젝션 몰딩 기술은 높은 생산성과 정밀도를 향상시켜 왔다. 본 고는 이러한 폴리머-하이브리드 옵틱 기술에 관한 최신 동향으로서 Optronics 340호에서 발췌, 정리한 것이다.
상한론의 '기기상충(其氣上衝)'과 '계지탕(桂枝湯)'에 대한 연구
이승준,김영목,Lee, Seung-Jun,Kim, Yeong-Mok 대한한의학방제학회 2012 大韓韓醫學方劑學會誌 Vol.20 No.2
In pathologically analyzing, 'Qi(氣)' is fall downed 'Zheng-Qi(正氣; Base energy of human body)' or 'Wai-Gan-Xie-Qi(外感邪氣; poisoned energy from outside of human body)'. And all extroverted symptoms from this 'Qi(氣)' is 'Shang-Chong(上衝)'. Also this symptom's basic mechanism is deficiency of 'Zhong-yang(中陽; basic active energy acting pivot)' by non-proper 'Xia-fa(下法; treatment way getting out focus to down side)' at early days of 'Tai-Yang-bing (太陽病; Primary stage symptoms when the cold energy of the outside tresspasses the external layer of body)'. And comparing herbs in medicines for treating 'Shang-Chong(上衝)' in Shang han lun with Japanese in Shang-han medical practitioner's view, there is 'Ping-Chong(平衝; Supress out bursting energy)''s effect when use 'Gui-zhi(桂枝; Cinnamomum cassia loureirii zeylanuicum)' for mass dosage. Based on these, 'Qi-Shang-Chong(氣上衝)' means all of the symptom's aspects which called 'Yang(陽)''s aspect that is extrovesity, dynamic and imminent by results of the experiment about Cinnamaldehyde which are the main ingredients of 'Gui-zhi(桂枝; Cinnamomum cassia loureirii zeylanuicum)' and clinical data of 'Gui-zhi-tang(桂枝湯)'.