TFT LCD의 산업개요와 시장전망

이상유,Lee, Sang-Yu 한국전자정보통신산업진흥회 1997 電子振興 Vol.17 No.12

삭시톡신과 그 유사체: 독성, 분석법, 국내외 오염도 및 관리 동향

이상유,임주희,우소영,최화영,박수빈,유차니,전향숙 한국식품위생안전성학회 2020 한국식품위생안전성학회지 Vol.35 No.6

마비성 패독(paralytic shellfish poisoning, PSP)에 의한 중독은 와편모조류(Dinoflagellates)가 생성하는 saxitoxin (STX)이 이매패류 등의 먹이활동에 의해 축적되고 이를 사람이 섭취함으로써 발생한다. 최근 분석기술의 발전으로 와편모조류가 STX외에도 gonyautoxin (GTX) group 및 Nsulfo carbamoyl toxins (C toxin) group 등 다양한 유사체들 을 생성하는 것으로 보고되고 있다. 이에 CODEX, EFSA 에서는 STX외 유사체의 안전관리를 위해 STX 및 유사체를 STX group으로 관리하고자 하는 움직임을 보이고 있다 . 국내의 경우도 STX 유사체를 생성하는 조류의 발생이 이미 보고되고 있으며 실제 홍합에서 유사체의 오염사례도 소수 보고되고 있다. 따라서 국제적인 움직임에 발맞추어 국내에서도 STX 및 유사체의 group 관리를 위한 준비가 필요할 것으로 사료된다. 본 연구에서는 STX 및 유사체의 체계적인 모니터링 및 안전관리의 기반을 마련하고자 STX 및 유사체의 이화학적 특성, 생성조류, 국내외 발생현황, 독성 및 상대독성계수, 분석법, 오염현황 및 관리현황에 대한 폭넓은 검토를 수행하고자 하였다. Paralytic shellfish poisoning (PSP) occurs when saxitoxin (STX), which is produced by harmful algae (dinoflagellates) and then accumulated in bivalve shellfish by filter-feeding, is consumed by humans. With recent advances in analysis technology, it has been reported that dinoflagellates also produce a variety of analogues such as the gonyautoxin (GTX) group and the N-sulfo-carbamoyl toxin (C toxin) group, in addition to STX. Accordingly, CODEX and the EFSA are stepping forward to manage STX and analogues as STX groups requiring safety management. In Korea, the occurrence of dinoflagellates producing STX analogues has already been reported, and contamination of analogues (GTX group, C toxin group) in live mussels has also been reported. In this study, in order to provide the basis for systematic monitoring and safety management of STX and analogues, their physicochemical characteristics, occurrence of dinoflagellates, toxicity and toxic equivalency factor, analytical method and occurrence were widely reviewed. This review is expected to contribute to strengthening the safety management of STX and its analogues.

구전신화 바리공주의 대중음악 콘텐츠화 연구

이상유(Sang Eu Lee),김정우(Jung Woo Kim) 한국문화융합학회 2023 문화와 융합 Vol.45 No.7

식품의 품질 및 안전 관리를 위한 테라헤르츠 분광/영상 기술의 응용

이상유(Sang Yoo Lee),우소영(So Young Woo),전향숙(Hyang Sook Chun) 한국식품과학회 2018 식품과학과 산업 Vol.51 No.1

Terahertz (THz) represents the portion of the electromagnetic radiation between the microwave and the infrared region and is within the frequency range of 0.1-10 THz. The ability of THz waves to pass through a wide variety of packaging materials, combined with their ability to characterize the molecular structure of many substances makes it an attractive tool for the application of food quality and safety management. This review provides current information on application of THz spectroscopy/imaging technology for food quality and safety management. The THz spectroscopy/imaging technology has been shown to be useful for detecting foreign bodies, vitamin/moisture, pesticides, antibiotics, melamine etc. However, major barriers to the adoption of THz spectroscopy/imaging for food quality and safety management include THz signal loss in heterogeneous food matrices, high costs of sources and detectors, and absence of a library for the wide group of food compounds. Further research is needed to overcome these barriers.

Vertical variation of sedimentary facies and depositional environment in the core section of the lower part of the Sindong Group, northwestern part of the Gyeongsang Basin

이상유(Sang-you Lee),황인걸(In Gul Hwang) 대한지질학회 2012 지질학회지 Vol.48 No.5

Natural Occurrence of Aflatoxigenic Aspergillus Species and Aflatoxins in Traditional Korean Fermentation Starters, Meju and Nuruk

우소영,이상유,Fei Tian,정아영,유차니,Seungyoon Kang,전향숙 한국식품위생안전성학회 2020 한국식품위생안전성학회지 Vol.35 No.5

Meju and nuruk (respectively soybean and malt) are traditional Korean fermentation starters that are vulnerable to contamination by harmful microorganisms such as aflatoxigenic fungi and their associated aflatoxins (AFs). In this study, Aspergillus spp. were isolated and identified from a total of 57 meju and 18 nuruk samples collected from Korean markets. Their potential aflatoxigenicity was investigated by examining the presence of three aflatoxin biosynthetic genes (aflO, aflP, and aflR) using multiplex polymerase chain reaction (mPCR) assays. Thereafter, aflatoxin production of isolates and the natural occurrence of AFs in meju and nuruk samples were analyzed by high-performance liquid chromatography (HPLC). A total of 177 Aspergillus isolates were identified and 130 isolates were obtained from meju samples. Of these, 25 isolates (19.2%) contained all three aflatoxin biosynthetic genes, and five (20%) of these isolates produced aflatoxins. Forty-seven of the Aspergillus isolates were obtained from nuruk samples, five of which (10.6%) expressed all three AF biosynthetic genes; however, none of these strains produced AFs. HPLC analysis showed that 88% (51/58) of the meju samples and 39% (7/18) of nuruk samples were not contaminated with AFs (below limit of detection). Among the isolates isolated from meju and nuruk, there were aflatoxigenic strains containing all three aflatoxin biosynthetic genes or producing aflatoxin in medium, but the frequency of aflatoxin contamination was low in the meju and nuruk samples.

대형 액정 디스플레이(LCD TV)의 백라이트 광원 개발 동향

박해일,이상유,석준형,Park, Hae-Il,Lee, Sang-Yu,Seok, Jun-Hyeong 한국정보디스플레이학회 2004 인포메이션 디스플레이 Vol.5 No.5

액정 디스플레이(LCD)의 대형화 및 저가격화와 더불어 전체 소비전력의 90% 이상, 모듈(module) 원가의 50% 이상을 차지하는 백라이트에 대한 연구가 활발히 진행되고 있다. 이에 기존의 냉음극 형광램프(CCFL)뿐만 아니라 원가 절감 및 특성 향상 기술로서 외부전극 형광램프(External Electrode Fluorescent Lamp), 면광원(Flat Fluorescent Lamp), 발광 다이오드 (Light Emitting Diode), 전계 방출램프(Field Emission Lamp) 등에 대한 개발이 활발히 진행되고 있는 바 이와 같은 다양한 기술의 경쟁을 통하여 보다 고품질 및 저원가 백라이트의 개발이 가능하여 액정 디스플레이의 경쟁력을 확대시킬 것으로 예상된다.

고체상 추출 전처리 및 HPLC-UV를 이용한 수산물 중 domoic acid의 분석

전향숙,김시은,이상유,박지은,정현진 한국식품위생안전성학회 2023 한국식품위생안전성학회지 Vol.38 No.5

본 연구는 패류 독소 중 기억상실성 독성을 유발하는 domoic acid의 분석법 개선, 검증 및 분석적용성을 살펴보 았다. SAX 카트리지 정제, 검체 및 추출용매 양의 변경 과 더불어 이동상을 용매구매 조건으로 변경시킨 분석법 은 지중해담치, 홍게 그리고 멸치의 세 가지 매트릭스를 대상으로 세 농도에 대하여 식품공전법과 비교하여 유효 성을 검증하였다. 그 결과 변경된 분석법은 LOD 0.02-0.03 mg/kg, LOQ 0.05-0.09 mg/kg, 일내 및 일간 정확도 86.2- 100.4%와 일내 및 일간 정밀도 0.2-4.0%로 CODEX가이 드라인을 만족하는 우수한 분석능을 나타내었다. 특히 변 경된 시험법에서는 domoic acid와 유사한 머무름 시간을 갖는 방해물질이 검출되지 않아 위양성 결과를 방지할 수 있을 것으로 생각된다. 더 나아가 본 분석법이 국내 유통 중인 수산물을 대상으로 적용될 수 있는지 확인하고자 식 품공전의 기억상실성 패독 분석법과 함께 수산물에 적용 하여 분석하였다. 그 결과 5종의 수산물 87건 중 공전시 험법으로 분석했을 때 domoic acid가 검출된 시료는 없었 으나 변경된 분석법을 통하여 멸치 1건에 대하여 0.14 mg/ kg의 domoic acid이 미량 검출되었다. 따라서 본 연구에 서 확립된 분석법은 수산물 중 domoic acid 분석에 활용 이 가능할 것으로 보인다. Domoic acid (DA), a neurotoxin produced naturally by diatoms, is responsible for incidents of amnesic shellfish poisoning. In this study, a modified analytical method was established to determine domoic acid in seafood using solid phase extraction cleanup and optimizing the amount of sample and extraction solvent to reduce interference effects. The modified method using high-performance liquid chromatography with ultraviolet detection was validated using three seafood matrices (mussel, red snow crab, and anchovy) at three concentrations (1, 2, and 4 mg/kg) and compared to the Food Code method. Compared to the Food Code method, the modified method showed better performance in terms of linearity (R2 >0.999), detection limit (0.02–0.03 mg/kg), quantification limit (0.05–0.09 mg/kg), intra-/inter-day accuracy (86.2–100.4%), and intra-/inter-day precision (0.2–4.0%). Furthermore, the method was successfully applied for the analysis of 87 seafood samples marketed in Korea, and DA was detected at a low concentration of 140 µg/kg in one anchovy sample. These results suggest that the modified method can be used for routine determination of DA in seafood.

Simple chromatographic determination of aflatoxins in Korean fermented soybean products doenjang, ganjang, and gochujang, with comparison of derivatization methods

우소영,옥현애,이상유,정아영,정태균,전향숙 한국식품과학회 2022 Food Science and Biotechnology Vol.31 No.4

Korean fermented soybean products doenjang, ganjang, and gochujang are vulnerable to contamination with aflatoxigenic fungi in the open fermentation envi- ronment. Therefore, simple and effective methods to determine aflatoxins (AFs) in these complex food matrices are needed. High-performance liquid chromatography with fluorescence detection using two derivatization methods for AF determination in three fermented soybean products was optimized and validated. Pre-column derivatization (preCD) of the AF extracts was performed using trifluo- roacetic acid, and post-column derivatization (PCD) was performed in a photochemical reactor for enhanced detection. Both derivatization methods resulted in accept- able performances for linearity (R2 [ 0.999), recovery (71–118%), and precision (\ 10.6%) values. Recovery and precision with preCD and PCD were similar, but the limit of detection was superior with PCD. When these analytical methods were applied to commercially available fermentedsoybean products, the AF levels of all commercial products were ranged from not detected to 6.06 lg/kg.

액정 디스플레이 TV의 면광원 백라이트 기술

박해일,변진섭,이상유,Park, Hae-Il,Byeon, Jin-Seop,Lee, Sang-Yu 한국조명전기설비학회 2005 조명.전기설비 Vol.19 No.1