홍삼 엑기스를 함유한 분말주의 제조 및 평가

이사원,최한곤,박정일,김종국 영남대학교 약품개발연구소 2000 영남대학교 약품개발연구소 연구업적집 Vol.10 No.-

To develop a dry alcohol containing red ginseng extract, dry alcohols composed of ethanol, water, dextrin and sodium lauryl sulfate were prepared using spray dryer, and their ethanol contents and encapsulation efficiencies were deter-mined. An optimal dry alcohol containing red ginseng extract was chosen and the feeling for its oral administration was eval-uated. Dextrin at dextrin/water weight ratios below 1.6/1 and ethanol at ethanol/water weight ratios below 1/1 remarkably increased both the ethanol contents and encapsulation efficiencies of dry alcohols. However, dextrin at dextrin/ water weight ratios above 1.6/1 and ethanol at ethanol/water weight ratio above 1/1 slightly decreased the both parameters. It might be due to the low solubility of dextrin in ethanol and limited diffusion coefficient of ethanol to the dextrin shell. Furthermore, 0.5%(w/w) sodium lauryl sulfate gave the maximum ethanol content of dry alcohol. The more increased amounts of red ginseng extract were added, the more increased amounts of ginsenoside Rb1 but the more decreased amounts of ethanol were encap-sulated in dry alcohols. A dry alcohol containing red ginseng extract was prepared with dextrin/ethanol/water(1/1/1, w/w/w) mixed solution, in which 0.5%(w/w) sodium lauryl sulfate and 20%(w/w) red ginseng extract were dissolved. It contained the ethanol contents of 31.17±1.33%(w/w) and ginsengoside Rb1 of 243.0±7.0㎍/g. It gave the moderate taste of red ginseng extract at its oral administration with or without water. Thus, the dry alcohol containing red ginseng extract can be further developed as a more convenient dosage form for red ginseng extract.

지역 문화적 특성에 기반한 중국 광부(廣府) 수향촌(水鄉村)의 공간색채 스펙트럼 융합 연구 - 광저우시(廣州市) 샤오저우촌(小洲村), 황푸촌(黃埔村), 포산시(佛山市) 펑첸촌(逢簡村)을 중심으로 -

이사원,김지은 한국전시산업융합연구원 2022 한국과학예술융합학회 Vol.40 No.3

In recent years, with the urbanization of Chinese cities, many characteristic village cultures around the cities are gradually disappearing, while the spatial color of each village is becoming more and more similar. The existence and development of village spatial color reflect the history, culture and regional characteristics of different areas. Therefore, this study started from the point that the study of village spatial color has emerged as an important task. Based on regional cultural characteristics, this study selects three Guangfu water villages as subjects and proposes a spatial color optimization solution. The research contents and results are as follows. Firstly, by studying the geographical history, humanistic thought and ethnic culture of Guangfu water villages, it is found that the spatial color of Guangfu water villages has a close relationship with the Five Elements Theory. The relationship is mainly reflected in three aspects: the five elements, mutual generation and restriction, and the traditional folklore concept. Secondly, in each village, this study takes the key ancient buildings as the important nodes and collects the spatial color data of the main roads among all the nodes. By analyzing three representative Guangfu water villages, it is confirmed that the spatial color environment of Guangfu water village has problems such as clutter and disorder. Finally, through the improvement of the spatial color spectrum, the colors that do not fit with the spatial color environment are eliminated so as to visually coordinate the spatial color spectrum. In addition, based on the relationship between the regional cultural characteristics of Guangfu water villages and color, colors that reflect cultural characteristics are added, and directions for improving the auxiliary color spectrum of commercial buildings in Guangfu water villages are proposed. It is hoped that this study will serve as a reference for improving the spatial color of other Guangfu water villages. 최근 몇 년간 중국 도시가 대규모 건설되면서 도시주변의 독특한 촌락 문화가 점차 사라지고 지역 공간색채의 동질화 현상도 심해져 가고 있다. 공간색채의존재와 발전은 해당 지역의 역사, 문화와 지역적 특색을 반영한다. 이에 본 연구는 촌락 공간색채 관련 연구가 중요한 과제로 부상하였다는 점에서 시작되었다. 본 연구의 목적은 지역 문화적 특성을 바탕으로하여, 광부 수향촌 3곳을 대상으로 해당 공간색채 스펙트럼 개선방안을 제시하는 것이다. 연구 결과 및 내용은 다음과 같다. 첫째, 광부 수향촌의 지리와 역사, 인문정신과 민족문화에 관한 연구를 통하여 광부 수향촌의 공간색채가 오행원소(五行元 素), 상생상극(相生相克), 전통 민속 관념 등 3가지 측면에서 중국 전통 오행설(五行說)과 밀접한 관련이 있다는 사실을 확인하였다. 둘째, 대표적인 광부 수향촌3곳을 연구 대상으로 삼아, 그 중 각 촌락의 핵심 고대 건축물을 중심으로 핵심 고대 건축물 사이의 간선도로의 공간색채를 수집하였다. 수집한 색채 데이터를통합하여 분석한 결과, 광부 수향촌의 공간색채 환경은 난잡하고 무질서하는 등 문제가 존재하고 있음을확인하였다. 셋째, 공간색채 스펙트럼 개선 작업을통하여 공간색채 환경에 어울리지 않는 색채를 제거함으로써 공간색채 스펙트럼의 시각적 조화를 이루도록 하였다. 또한, 광부 수향촌의 지역 문화적 특성과 색채 간의 관계를 바탕으로 문화적 특성을 드러낼 수있는 색채를 추가하여 광부 수향촌 상업 건축물의 보조색 스펙트럼 개선 방향을 제시하였다. 제시된 연구결과를 통해 광부 수향촌 고유의 문화를 담아낸 촌락공간색채 개선 참고가 될 수 있기를 기대한다.

홍삼 엑기스를 함유한 분말주의 제조 및 평가 ( Preparation and Evaluation of Dry Alcohol Containing Red Ginseng Extract )

이사원,최한곤,박정일,김종국 고려인삼학회 2000 Journal of Ginseng Research Vol.24 No.1

RFID를 위한 다중편파 안테나 시스템 설계 및 구현

이사원(Sa Won Lee) 산업기술교육훈련학회 2015 산업기술연구논문지 (JITR) Vol.20 No.4

This paper presented polarization reconfigurable RFID reader antenna operating at UHF band. The proposed reader antenna consists of microstrip antenna with dual feed networks, two SPDT switches, a SP4T switch and 3dB hybrid coupler. Polarization selective circuit located at the back of ground plane for minimizing effect on antenna. Fixed phase shifter and impedance matching circuit were added for compensation mismatching and phase difference between two feeding posts. The switching voltage is controlled by low & high voltage using ATmega128. Through control of voltage of switches, the proposed reader antenna can select horizontally linear polarization, vertically linear polarization, left-hand circular polarization (LHCP) and right hand circular polarization (RHCP). The proposed reader antenna satisfied 2:1 VSWR at 881MHz~952MHz with horizontally linear polarization and 873MHz~959MHz with vertically linear polarization. And the axial ratio of antenna measured under 3dB at UHF RFID band with circular polarization. The proposed antenna can select appropriative polarization due to user environment and polarization of tag antenna. So it can minimize PLF (Polarization Loss Factor) and improve inrerrogation range about 1.5m to up to 3m.

UHF RFID 시스템을 위한 Polarization selective 안테나 연구

이사원(Sa-Won Lee),송우영(Woo-Yong Song) 한국컴퓨터정보학회 2010 韓國컴퓨터情報學會論文誌 Vol.15 No.7

본 논문은 UHF RFID 시스템을 위해 편파를 선택할 수 있는 리더 안테나를 설계 및 구현하였다. 제안된 리더 안테나는 두 개의 급전부를 가지는 마이크로 스트립 패치 안테나와 두 개의 SPDT 스위치와 하나의 SP4T 스위치와 3dB hybrid coupler로 구성되어 있다. 각각의 스위치 전압을 조절하여 수직 방향의 선형 편파와 수평 방향의 선형 편파, 좌수 원형 편파와 우수 원형 편파를 선택할 수 있다. 제안된 안테나는 902MHz~928MHz 대역에서 VSWR 2:1 기준으로 UHF RFID 주파수 대역인 902MHz~928MHz를 만족한다. 안테나의 최고이득은 X-Y Plane을 기준으로 선형 편파가 선택되어질 때 7.71dBi, 7.55dBi 로 측정되었고 원형 편파가 선택되어질 때 7.31dBic, 7.81dBic 로 측정되었다. 또한 원형 편파(LHCP, RHCP)가 선택 되어질 때 축비는 각각 2.01~2.83dB, 2.02~2.60dB로 측정되었고 이는 3dB 이하의 축비를 만족한다. TIn this paper, it is designed the polarization selective antenna for UHF RFID system. The proposed antenna is consist of microstrip patch antenna with dual feeding and two SPDT switches and a SP4T switch and 3dB hybrid coupler. Through control of voltage of switches, the proposed reader antenna can select horizontally linear polarization, vertically linear polarization, left-hand circular polarization (LHCP) and right hand circular polarization (RHCP). The proposed reader antenna satisfied 2:1 VSWR at 902MHz~928MHz. and it has under 3dB AR(axial ratio). Peak gain of antenna is 7.71dBi, 7.55dBi with linear polarization and 7.31dBic, 7.81dBic with circular polarization at x-y plane. Also Axial ratio of antenna is 2.01~2.83dB and 2.02~2.60dB respectively. It is satisfied 3dB axial ratio.

안테나 및 레이다 분야 : UHF RFID 시스템을 위한 Polarization Selective 안테나 설계 연구

이사원 ( Sa Won Lee ),송우영 ( Woo Yong Song ) 한국항행학회 2010 韓國航行學會論文誌 Vol.14 No.2

중국 광부(廣府) 수향촌(水鄉村)의 문화구성과 공간색채 관계성 융합 연구

이사원(Li, Si Yuan),김지은(Kim, Ji Eun) 한국전시산업융합연구원 2022 한국과학예술융합학회 Vol.40 No.1

CPW를 이용한 대역통과 필터의 성능분석

金明中,李思遠 충주대 산업과학기술연구소 1997 産業科學論文集 Vol.5 No.-

In this paper describes the design and performance of shunt inductively coupled bandpass filters implemented on open coplanar waveguide. This structure exhibits low radiation loss due to the removal of the capacitively coupled gaps encountered in end or edge coupled filters. The admittance inverter parameters of the coupling gaps between resonant sections are deduce from experiment, and bandpass filter design rules are developed. This allows easy filter synthesis from "prototype" low-pass designs. Measurements of single section resonator quality factors are used to predict filter insertion losses.

마이크로스트립을 利用한 결합 선로 필터의 設計

柳烈國,李思遠,金洪五 충주대학교 1997 한국교통대학교 논문집 Vol.32 No.2

In this paper, a design method of a bandpass filter using microstrip coupled lines has been studied. In order to verify the appropriateness of the design method based on the basic theory, a microstrip coupled-lines bandpass filter with the center frequency of 5 GHz,the order of 4 and 6, and the ripple of 0.5dB was designed and tested. The test results were compared to the simulation results by Touchston, a simulation tool. As a conclusion, we found that the theoretical value well agrees with the exprimental one.

프로스타글란딘 E₁ 마이크로에멀젼이 함유된 액상좌제의 제조 및 평가

김정환,이사원,박경미,최한곤,김종국 영남대학교 약품개발연구소 2000 영남대학교 약품개발연구소 연구업적집 Vol.10 No.-

The purpose of this study is to develop a transurethral liquid suppository containing prostaglandin E_(1)(PGE_(1))-loaded microemulsion, which undergoes a phase transition to gels at body temperature. The effects of oils, ethanol as solvent and HCI as pH-controlling agent on the physicochemical properties of liquid suppositories composed of poloxamer P 407. P 188 and carbopol was investigated. The stability of PGE_(1) and release of PGE_(1) from liquid suppository were evaluated. Oils such as Neobee and soybean oil significantly decreased the gelation temperature but increased the gel strength of liquid suppository due to their strongly binding with the components of liquid suppository base. However, ethanol slightly did the opposite. The pH of liquid suppositories hardly affected the gelation temperature and gel strength due to addition of very small HCI(0.005-0.01%). A liquid suppository [PGE_(1)/P 407/P 188/carbopol/Neobee/ethanol/HCI(0.4/14/14/0.4/7/2/0.005%)], which had the gelation temperature (34.2±0.6℃) and gel strength (31.35±4.37 sec) suitable for liquid sup-pository system, was easily administered and not leak out from the body. About 60% of PGE_(1) was released out within 2h from this formulation. It was shown that the release of PGE_(1) was proportional to the square root of time, indicating that PGE_(1) might be released from the suppository by Fickian diffusion. It was stable at 4℃ for at least 2months. The results suggest that transurethral liquid suppository containing prostaglandin E_(1)-loaded microemulsion is thought to be a con-venient, safe and effective dosage form for PGE_(1). However, it should be further developed as a more convenient and stable dosage form for PGE_(1).