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탠덤 매스 검사(Tandem Mass Spectrometry)를 이용한 선천성 대사이상 선별검사 10년간의 분석
이보미,이지윤,이정호,김석영,김종원,민영기,손운흥,송정한,우향제,윤혜란,이용화,최교영,최태윤,이동환,Lee, Bomi,Lee, Jiyun,Lee, Jeongho,Kim, Suk Young,Kim, Jong Won,Min, Won-Ki,Song, Woon Heung,Song, Jung Han,Woo, Hang Jae,Yoon, Hye Ran,Lee, Yong 대한유전성대사질환학회 2017 대한유전성대사질환학회지 Vol.17 No.3
Purpose: From the early 1990's, use of Tandem mass spectrometry in neonatal screening test, made early stage detection of disorders that was not detectable by the previous methods of inspection. This research aims to evaluate the frequency of positive results in national neonatal screening test by Tandem mass spectrometry and its usefulness. Methods: A designated organization for inherited metabolic disorder executed neonatal screening test on newborns using Tandem mass spectrometry from January 2006 to December 2015, followed by the investigation of these data by the Planned Population Federation of Korea (PPFK), and this research analyzed those inspected data from the PPFK. Results: Among total childbirth of 4,590,606, from January 2006 to December 2015, 3,445,238 were selected for MS/MS and conduction rate was 75.1%. 261 out of the selected 3,445,238 were confirmed patients and for last decade, detection rate of total metabolic disorder was 1/13,205. In 261 confirmed patients, 120 had an amino acid metabolic disorder and its detection rate was 1/28,710 and 110 had an organic acid metabolic disorder and detection rate was 1/31,320. Also, 31 had a fatty acid metabolic disorder and detection rate was 1/13,205. Conclusion: Inherited metabolic disorder is very rare. Until now, it was difficult to precisely grasp an understanding on the national incidence of inherited metabolic disorder, due to lack of overall data and inconsistent and incomplete long-term result analysis. However, this research attempted to comprehensively approach the domestic incidence, by analyzing previous 10 years of data.
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이보미,신나나,Lee, Bomi,Shin, Nana The Korean Home Economics Association 2021 Human Ecology Research(HER) Vol.59 No.4
This study investigated the association between children's perceptions of autonomy support from mothers and teachers in relation to academic procrastination. It also examined the role of self-efficacy for self-regulated learning in mediating these effects. The sample comprised 372 fifth and sixth grade elementary school students from Seoul, Korea. Each completed a questionnaire regarding mothers' and teachers' autonomy support, children's self-regulated learning efficacy, and academic procrastination. The results indicated that whereas mothers' autonomy support had a direct effect on children's academic procrastination, teachers' support did not. In other words, children who perceived higher levels of autonomy support from mothers tended to exhibit less academic procrastination. Regarding indirect paths, children who perceived higher levels of mothers' and teachers' autonomy support displayed greater efficacy for self-regulated learning, which corresponded to lower levels of academic procrastination. The discussion highlights the vital roles of autonomy support from mothers and teachers in enhancing children's feelings of effective self-regulated learning and encouraging them to complete academic tasks. Furthermore, the present study considered not only outward behavioral factors but also the underlying cognitive and affective aspects of delaying behavior that underpin the effects of self-regulated learning efficacy and autonomy support of mothers and teachers on academic procrastination.
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진행기준 수익인식 방법과 재무분석가 이익예측 - 미청구공사 계정을 중심으로 -
이보미,박보영,Lee, Bo-Mi,Park, Bo-Young 대한경영정보학회 2017 경영과 정보연구 Vol.36 No.3
본 연구는 수주산업 기업의 진행기준 수익인식 방법이 재무분석가 이익 예측 정보에 미치는 영향을 분석한다. 구체적으로 미청구공사 계정 잔액 보고여부 및 잔액 수준에 따라 달라지는 재무분석가 이익예측 정보의 특성을 살펴보았다. 미청구공사 계정 정보는 K-IFRS 도입 이후부터 제공되고 있으므로, 본 연구는 2010년부터 2014년까지 한국거래소에 상장된 기업 중 수주산업에 속한 453개 기업-연도 표본을 대상으로 분석하였다. 분석결과, 미청구공사 계정 잔액이 존재하는 기업은 미청구공사 계정 잔액이 없는 기업에 비해 재무분석가 이익예측 정보의 정확성이 낮았고, 더불어 미청구공사 보고금액의 수준이 높아질 경우 재무분석가 이익예측 정보의 정확성이 감소됨을 확인하였다. 미청구공사 계정은 수주업체 수익(진행률) 인식이 발주자의 수익 인정 시점(실제진척도) 보다 먼저 인식될 경우 생성된다. 이는 진행률 측정 시 경영자의 재량적인 판단과 추정이 가능하기 때문이며, 결국 실제진척도와 진행률의 차이는 재무제표의 예측가치를 하락시킨다. 따라서 진행기준에 의한 수익인식 방법을 적용 시 미청구공사 잔액을 보고한 기업의 경우, 재무분석가의 이익예측은 보다 어려울 수 있음을 본 연구의 결과가 보여준다. 추가적으로 미청구공사 계정잔액을 보고한 기업은 재무분석가의 이익예측 성향이 낙관적인 것으로 나타났다. 본 연구는 경영자에게는 실제진척도를 반영할 수 있는 진행률 측정 방식의 도입과 더불어 진행률 측정시에 자의적인 조정과 추정을 줄이는 노력을 제안하며, 투자자들에게는 수주산업의 진행기준 회계처리의 특성을 감안한 투자와 분석을 권고한다. 아울러 본 연구의 결과는 정책당국의 수주산업 회계투명성 제고 방안에도 힘을 실어 준다. This study investigates the effect of revenue recognition by percentage of completion method on financial analysts' earnings forecasting information in order industry. Specifically, we examines how the analysts' earnings forecast errors and biases differ according to whether or not to report the unbilled revenue account balance and the level of unbilled revenue account balance. The sample consists of 453 firm-years listed in Korea Stock Exchange during the period from 2010 to 2014 since the information on unbilled revenue accounts can be obtained after the adoption of K-IFRS. The results are as follows. First, we find that the firms with unbilled revenue account balances have lower analysts' earnings forecast accuracy than the firms who do not report unbilled revue account balances. In addition, we find that the accuracy of analysts' earnings forecasts decreases as the amount of unbilled revenue increases. Unbilled revenue account balances occur when the revenue recognition of the contractor is faster than the client. There is a possibility that managerial discretionary judgment and estimation may intervene when the contractor calculates the progress rate. The difference between the actual progress of the construction and the progress recognized by the company lowers the predictive value of financial statements. Our results suggest that the analysts' earnings forecasts may be more difficult for the firms that report unbilled revenue balances as applying the revenue recognition method based on the progress criteria. Second, we find that the firms reporting unbilled revenue account balances tend to have higher the optimistic biases in analysts' earnings forecast than the firms who do not report unbilled revenue account balances. And we find that the analysts' earnings forecast biases are increases as the amount of unbilled revenue increases. This study suggests an effort to reduce the arbitrary adjustment and estimation in the measurement of the progress as well as the introduction of the progress measurement method which can reflect the actual progress. Investors are encouraged to invest and analyze the characteristics of the order-based industry accounting standards. In addition, the results of this study empower the accounting transparency enhancement plan for order industry proposed by the policy authorities.
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Bacillus safensis MA-01 유래 알파-만노사이데이즈의 효소학적 특성
이보미,김주원,박제권,Lee, Bo Mi,Kim, Joo Won,Park, Jae Kweon 한국해양바이오학회 2015 한국해양바이오학회지 Vol.7 No.1
An extracellular alkaline ${\alpha}$-D-mannosidase produced by a strain named as MA-01 was produced and its preliminary enzyme activity was characterized. Upon determining the 16S rDNA sequence and its homology search, the strain was identified to be one of species of the Bacillus safensis. Localization of enzyme was elucidated that ${\alpha}$-D-mannosidase can be found in culture medium as an extracellular enzyme. In addition, partial enzyme activity of 63% compared with the extracellular enzyme activity was observed in membrane protein. The optimal pH and temperature of the ${\alpha}$-D-mannosidase were pH 7.5 and $37^{\circ}C$, respectively. The $K_m$ and $V_{max}$ values of the ${\alpha}$-D-mannosidase in crude enzyme toward p-nitrophenyl-${\alpha}$-D-mannopyranoside were determined to be $455.6{\mu}M$ and $10.8{\mu}mole/min/mg$ of protein, respectively. To the best of our knowledge, this is the first report described the alkaline ${\alpha}$-D-mannosidase from the family of B. safensis.
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이보미,정삼봉,남상용,Lee, Bo-Mi,Jeong, Sam-Bong,Nam, Sang-Yong 한국재료학회 2012 한국재료학회지 Vol.22 No.5
Ionomer is a thermoplastic that is composed of covalent bonds and ionic bonds. It is possible to use this material in processes such as injection molding or extrusion molding due to the material's high oil resistance, weatherproof characteristics, and shock resistance. In this study, a new ionomer having a multifunctional group was prepared by a stepwise neutralization system with the addition of acidic and salt additives. In step I, to increase the contents of the multifunctional group and the acid degree in ethylene acrylic acid (EAA), MGA was added to the ionomer resin (EAA). A new ionomer was prepared via the traditional preparation method of the ionic cross-linking process. In step II, metal salt was added to the mixture of EAA and MGA. The extrusion process was performed using a twin extruder (L/D = 40, size : ${\varphi}30$). Ionomer film was prepared for evaluation of gas permeability by using the compression molding process. The degree of neutralized and ionic cross-linked new ionomer was confirmed by FT-IR and XRD analysis. In order to estimate the neutralization of the new ionomer film, various properties such as gas permeation and mechanical properties were measured. The physical strength and anti-scratch property of the new ionomer were improved with increase of the neutralization degree. The gas barrier property of the new ionomer was improved through the introduction of an ionic site. Also, the ionic degree of cross-linking and gas barrier property of the ionomer membrane prepared by stepwise neutralization were increased.
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복수의 작은 트리에 대한 바이너리 검색을 이용한 IP 주소 검색 구조
이보미,임혜숙,김원정,Lee Bo mi,Lim Hye sook,Kim Won jung 한국통신학회 2004 韓國通信學會論文誌 Vol.29 No.12C
인터넷 접근 기술의 발달은 보다 큰 인터넷 bandwidth를 필요로 하게 되었고 라우터에서의 빠른 패킷 처리를 요구하게 되었다. 라우터에서의 어드레스 경색은 일초에 수천만개 이상으로 입력되는 패킷에 대하여 실시간으로 처리되어야 하는 중요한 기능이다. 본 논문에서는 효율적인 어드레스 검색을 위한 소프트웨어에 기반한 새로운 검색 구조를 제안한다. 라우팅 테이블을 여러 개의 밸런스 트리들로 구성하여 하나의 SRAM에 저장하고 각각의 트리에 대해 순차적으로 바이너리 검색을 수행하는 방식이다. 본 논문에서 제안하는 구조는 약 40,000 여개의 프리픽스를 갖는 라우팅 테이블을 저장하기 위하여 301.7KByte의 작은 사이즈 SRAM을 사용하고 평균 11.3번의 메모리 접근으로 주소 검색이 가능한 구조이다. Advance of internet access technology requires more internet bandwidth and high-speed packet processing. IP address lookups in routers are essential elements which should be performed in real time for packets arriving tens-of-million packets per second. In this paper, we proposed a new architecture for efficient IP address lookup. The proposed scheme produces multiple balanced trees stored into a single SRAM. The proposed scheme performs sequential binary searches on multiple trees. Performance evaluation results show that p개posed architecture requires 301.7KByte SRAM to store about 40,000 prefix samples, and an address lookup is achieved by 11.3 memory accesses in average.
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차세대 지적정보서비스 구현 전략 연구 - 대한지적공사 사례를 중심으로 -
이보미,이용문,Lee, Bo-Mi,Lee, Yong-Mun 한국공간정보학회 2008 한국공간정보학회지 Vol.16 No.1
본 연구는 급변하는 국내외 IT환경에 유연하게 대처하고 대한지적공사(이하 공사) 내부 역량을 강화하기 위한 방안으로써 지적정보시스템에 대한 SOA(Service Oriented Architecture) 사상의 도입 필요성을 연구의 핵심으로 한다. Enterprise GIS, SOA 등의 최신 IT 패러다임의 현황 파악을 통해 차세대 지적정보서비스의 개념을 정립하였다. 국내외의 SOA 도입사례 등 최근 정보시스템 동향을 알아보고 이를 통해 시사점을 제시하였다. 또한, 공사보유 정보시스템에 대한 개괄적 분석을 수행하고, 시스템별 SOA 성숙도를 진단하였다. 이를 기반으로 차세대 지적정보서비스 구현을 위한 공사 환경에 맞는 SOA 로드맵을 수립하였다. 이는 통합과 공유를 지향하는 미래 지향적인 정보시스템 구축을 위한 핵심적 단계로써, 공사는 내부적으로 정보시스템 인프라에 대한 중복을 배제하고 통합 및 재활용에 핵심 역량을 집중함이 바람직할 것으로 판단된다. This study aims to show why we have to introduce SOA paradigm in the Cadastral Information System for coping with domestic and foreign IT environments flexibly and strengthening inner capability. We search the trend of up-to-date IT paradigm such as Enterprise GIS, SOA and etc. from this, we worked out the concept of Cadastral Information System. we also could see the introduction case of the domestic and foreign next generation Cadastral Information System, there is implications for us. also, we analysis the general condition about information system which KCSC(Korea Cadastral Survey Corporation) own in a general way and estimate the SOA level degree for each information system. and on that base, we set up SOA loadmap for implementation the next generation of Cadastral Information Service. This is an important step for building ideal future information systems which KCSC hope to be. For realizing this, we focus our inner capability on integration without duplicate and re-using the inner information infra.
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