Double-blind test에 의한 Moltase 의 효력평가(?力評價)

이동호,이태희,Lee, Tong-Ho,Lee, Tae-Hee 대한약리학회 1970 대한약리학잡지 Vol.6 No.1

소화불량(消化不良)을 호소(呼訴)하는 학생(學生) 및 환자(患者)에게 placebos 투여(投與) 및 double-blind test에 의하여 식욕부진(食慾不振), 구역, 구토, 트림, 공복통(空腹痛), 상복부통(上腹部痛), 상복부포만감(上腹部飽滿感), 복부팽만(腹部膨滿), 변비(便秘), 설사(泄瀉) 등의 증상(症狀) 및 위산도(胃酸度)에 대한 Moltase의 효력(?力)을 평가(評價)할 것을 시도(試圖)하여 1) 전반적(全般的)으로 Moltase투여(投與)가 placebos 투여(投與)보다 소화불량증상(消化不良症狀)을 소실(消失) 또는 경감(輕減)시키는 효력(?力)이 켰으며 특히 상복부통(上腹部痛), 상복부포만감(上腹部飽滿感), 복부팽만(腹部膨滿) 및 식욕부진(食慾不進)에 대하여 현저(顯著)한 치료효과(治療?果)가 있으며, 2) 유리위산(遊離胃酸)을 증명(證明)치 못하였던 9명(名)의 환자중(患者中) 6명(名)에서 Moltase 복용후(服用後) 유리위산(遊離胃酸)을 증명(證明)케 되었다. 1) Efficacy of Moltase, a digestive enzyme preparation, was evaluated by double-blind test. 2) The clinical symptoms assessed in this study were anorexia, vomiting, nausea, eructation, hunger pain, epigastralgia, fullness in epjgastrium, abdominal fullness, constipation, and diarrhea. Effect of Moltase on gastric acidity was also examined by double-blind test. 3) People subjected to this study were 42 students and 22 patients who had signs of chronic dyspepsia. 4) In general, the clinical symptoms were more effectively improved by Moltase than placebos. The marked differences in efficacy between both medication were observed in epigastralgia, fullness in epigastrium, abdominal fullness, and anorexia. 5) Six out of 9 patients with no free gastric acid became to have free gastric acid after Moltase medication.

고무에 있어서 압축응력이 열확산계수에 미치는 영향

이동호(Tong Ho Lee),유갑종(Kap Jong Riu),김기완(Ki Wan Kim) 대한공업교육학회 1977 대한공업교육학회지 Vol.2 No.1

Generally packing gives rise to frictional heat. Thermal diffusivity is one of the main factors on calculation of heat transfer. In rubber, when compressive stress is applied, compressive as a factor of changing thermal diffusivity in rubber has not been reported. The factors being influenced on thermal diffusivity are density, specific heat and thermal conductivity. When compressive stress is applied, the variations of density and thermal conductivity are considered. Therefore compressive stress changes thermal diffusivity. In this paper, the relationship between thermal diffusivity and comperssive stress is studied through experiment. It is applied the well-known relation between temperature change and Fourier number in the case of transient conduction in heat transfer with negligible thermal resistivity. Thermal diffusivity α (㎠/sec) is found to vary with compressive stress P (㎏/㎠) according to the following equation; α = 1.434 × 10^-3 + 1.387 × 10^-6 P

REDD의 국제적 논의 동향과 정책적 함의

김통일 ( Tong Il Kim ),김성일 ( Seong Il Kim ),( Victor K Teplyakov ),이동호 ( Dong Ho Lee ),최가영 ( Ga Young Choi ) 한국산림과학회 2011 한국산림과학회지 Vol.100 No.4

REDD is recognized as a cost-effective and the most appropriate way of managing global GHG emissions. It is negotiated in a global context under the UNFCCC. The main issues of the REDD mechanism are divided into two parts: 1) developing forest carbon verification and measurement system for reducing emissions from deforestation and forest degradation, 2) establishing an appropriate system of incentives for developing countries. REDD can provide stability in carbon offset credits. However, the most important task is to establish a clear legal framework and appropriate governance structures with relevant countries. There is a wide opportunities for Republic of Korea to take a lead in cutting off greenhouse gasses in the Post-Kyoto period.

Partial Amino Acid Sequence of the Beta - Chain of Human Serum Haptoglobin and Its Genetic Implication to the Evolution of Proteins

이동호,Bowman, B. H. 생화학분자생물학회 1973 BMB Reports Vol.3 No.2

Beta-chain of human serum haptoglobin was isolated from purified type 1-1 haptoglobin, and the tryptic and chymotryptic peptides were separated by ion-exchange chromatography using automatic amino acid analyzer. N-terminal amino acid was determined by dansylation or by Edman reaction, and C-terminal amino acid was determined by carboxypeptidase method. Partial amino acid sequences of N-terminal and C-terminal were obtained, and compared with the other well-known proteins whose sequences were already determined by others, and a possible genetic mechanism of protein evolution was briefly discussed.

5-Hydroxytryptamine의 Ouabain 作用에 미치는 影響

李東豪 全南大醫大 1970 전남의대학술지 Vol.7 No.2

물질의 상태와 용액에 관련된 탐구실험 수업연구

송호봉,이동호 京畿大學 社會科學硏究所 2001 경기대학교 기초과학논문집 Vol.14 No.1

Studies on Canine Serum Haptoglobin

심봉섭,강윤세,이동호,오세근 생화학분자생물학회 1973 BMB Reports Vol.3 No.2

Canine serum haptoglobin was purified by DEAE-cellulose chromatography, ammonium sulfate fractionation, starch block electrophoresis and finally by Dextran gel filtration. The solubility of canine serum haptoglobin was slightly higher than human type 1-1 haptoglobin Immunoelectrophoretic mobility of canine serum haptoglobin was very slightly slower than human type 1-1 haptoglobin both in free and Hb-complexed states. On the other hand it migrated faster than human type 1-1 haptoglobin in starch gel electrophoresis both in free and Hb-complexed states, because of smaller molecular size. Canine serum haptoglobin also formed so-called Hp-Hb intermediate as well as human haptoglobin. Canine serum haptoglobin also composed of two kinds of polypeptide chains. The molecular weight of canine alpha-chain was estimated to be 10, 500 and that of beta-chain to be 30,000. Canine beta-chain migrated faster than human or swine beta-chain, and canine alpha-chain migrated very slower than human and swine alpha-chain in acid-urea-starch-gel electrophoresis. From the above results, it can be said that the subunits composition of canine: serum haptoglobin is same to human type 1-1 and swine serum haptoglobin. Likewise, the composition of Hp-Hb complex and Hp-Hb intermediate of canine haptoglobin would be similar to those of human and swine haptoglobins.

Studies on Swine Serum Haptoglobin

윤창수,심봉섭,강윤세,이동호 생화학분자생물학회 1973 BMB Reports Vol.3 No.2

1. Swine serum haptoglobin was purified by DEAE-cellulose chromatography. starch block electrophoresis and finally by gel filtration. 2. The solubilty of swine serum haptoglobin was slightly higher than human type 1-1 haptoglobin, i. e., it precipitated 65 percent saturation of ammonium sulfate. 3. The electrophoretic mobility of swine serum haptogtobin is slower than human type 1-1 haptoglobin and retardation of mobility of swine haptoglobin by forming hemoglobin complex was very slight. For this reason, in starch gel electrophoresis swine Hp-Hb complex migrated faster than human type 1-1 Hp-Hb complex. 4. Swine serum haptoglobin also forms so-called Hp-Hb intermediate as well as human haptoglobin. However, it is difficult to demonstrate by ordinary starch gel electrophoresis, since retardation of mobility of swine haptoglobin by formation of Hp-Hb complex is very slight. 5. Some antigenic determinants of swine serum haptoglobin are masked by hemoglobinbinding. 6. It was found that the molecular weight of swine serum haptoglobin is similar to humar type 1-1 haptoglobin, i. e., around 89, 000, by gel filtration technique. 7. Swine serun haptoglobin is composed of two kinds of polypeptide chains. 1'he smaller alpha-chain was similar to human alpha^(IS)-chain, and the larger beta-chain was similar to human beta-chain The subunit structure of swine haptoglobin is α₂β₂. 8. Swine serum haptoglobin binds with hemoglobin at the beta-chain like human haptoglobin. 9. The swine Hp-Hb complex is composed of equimolar haptoglobin and hemoglobin, while Hp-Hb intermediate is composed of one molecule of haptoglobin and half-molecule (dimer) of hemoglobin.

유전성 당뇨병의 model mice에서 외분비 췌장의 세포학적 및 기능적 변화

박형진,박형진,김정미,김정미,최월봉,김남중,이동호,이정열,오양석 대한해부학회 1992 Anatomy & Cell Biology Vol.25 No.1