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윤교복 ( Kyo Bok Yoon ),김종술 ( Jong Sool Kim ),정동수 ( Dong Su Chung ),박양주 ( Young Joo Park ),이유섭 ( You Sub Lee ),한정희 ( Jeong Hee Han ) 한국가축위생학회 1999 韓國家畜衛生學會誌 Vol.21 No.2
The present study was carried out to investigate the prevalence of brucellosis in Kyungbuk area for the 3 years from 1966 to 1998. Collective milk samples were routinely screened to detect positive farms by using the milk ring test(MRT), and serum agglutination test was performed to detect sero-positive individuals in the MRT positive farms. Attempt were made to isolate the causative organismas from slaughtered sero-positive reactors and some biochemical and polymerase chain reation characters of the isolates were also made to identify the organisms. Seroprevalence to brucellosis in peoples who are close contact with infected dairy herds was also investigated. Brucellosis of dairy cattle was rare before 1997, but has been broken more frequently since early 1998. By the MRT for dairy herds, positive rate was gradually increased every year 0.6% in 1996, 1.5% in 1997, 3.9% in 1998. Among 262 MRT-positive herds, only 21 herds(8.0%) showed positive brucellosis in serological test. The isolation rates of Brucella sp from tested materials were 51.2% in supramammary glands, 39.5% in milks, and 50.0% in pulmonary lymphnode, respectively. Isolated strain and biotype were Brucella(B) arbortus biotype 1 in 26 heads, and were B suis biotype 1 in 2 heads. Isolated strain and vaccine strain were very similar in their colony morphology and staining. In drug susceptibility, isolated stains(B abortus) and vaccine strain(B abortus RB-51) were sensitive to ampicillin, gentamycin, kanamycin, neomycin, penicillin, streptomycin, and tetracycline, but resistant to erythromycin. In the PCR, field strains reacted to BA and 1S711 primers, and vaccine strain reacted to BA, 1S711, and RB51 primers. In the plate agglutination test of 96 sera of human contacted with animals, serum antibody titer detected 1: 100 in one person, 1 : 200 in one, and below 1 : 25 in the others.
CMA-ES를 활용한 수정질점탄도모델의 탄도수정계수 설정기법
안세일,이교복,강태형,An, Seil,Lee, Kyo Bok,Kang, Tae Hyung 한국군사과학기술학회 2016 한국군사과학기술학회지 Vol.19 No.1
To make a firing table of artillery with trajectory simulation, a precise trajectory model which corresponds with real firing test is required. Recent 4-DOF modified point mass trajectory model is considered accurate as a theoretical model, but fitting coefficients are used in calculation to match with real firing test results. In this paper, modified point mass trajectory model is presented and method of setting ballistic coefficient is introduced by applying optimization algorithms. After comparing two different algorithms, Particle Swarm Optimization and Covariance Matrix Adaptation - Evolutionary Strategy, we found that using CMA-ES algorithm gives fine optimization result. This fitting coefficient setting method can be used to make trajectory simulation which is required for development of new projectiles in the future.
김광재,윤교복,최봉출,신은경,김종술,박양주,이유섭 한국동물위생학회 1997 韓國家畜衛生學會誌 Vol.20 No.4
This study was carried out to Investigate the biochemical characteristics, antibiotic susceptibility, serogroups and pili producibility test of enterotoxigenic Escherichia coli(ETEC) isolated from piglets with diarrhea in Kangwon province from March to October 1996. 1. Sixty eight E coli strains were isolated from 72 piglets with diarrhea and the biochemical and cultural reaction were compared with the classification criteria of Edwards and Ewing. 2. The serogroups of 26 isolates were classified as 08 : K87 6(8.8%), O20 : K1O1 4(5.9%), O141 : K85 4(5.9%), 09 : K103 : P987 3(4.4%), O45 : K 2(2.9%) 0139 : K82 2(2.9%), O64 : $K^{-}$2(2.9%), O149 : K91 1(1.5%), O157 : K88ac 1(1.5%) and O115 : $K^{-}$1(1.5%), respectively. 3. In antibiotic susceptibility test, the isolates showed high susceptible to Ak, Eno, Na, Gm, Am and Km, whereas resistance to Tc, Sm and Cf. 4. Sixty one strains(89.7%) of 68 I coli Isolates were resistant to one or more drugs. The isolates resistant to 2 and 3 or more drugs were 60.3% and 19.1%, respectively. Amog the 16 multiple resistant patterns, Sm Tc(11.5% ), Cf Sm Tc(11.5% ), Cf Cp Sm Su Tc(9.8% ) and Cf Cp Sm Su Tc(8.2%) patterns were frequently observed. 5. MRHA of guinea pig erythrocytes was detected in 9 out of 26 OK serotype and 9 out of 42 unidentified serotypes. MRHA titers of serotypes showed from 16 to 32 in O141 : K85 and no titers in O139 : K82. 6. By the GM1 ganglioside ELISA, $\beta$-, $\alpha$-, and $\gamma$-hemolysin producing strains was detected as 36, 6, and 5 from heat labile enterotoxin(LT) of 47 ETEC, respectively. The distribution of LT toxin from 112 isolates was showed $\beta$- hemolysin, 2 isolates $\alpha$-hemolysin and 3 isolates $\gamma$-hemol-ysin from 26 OK serotypes.