구강 백반증 진단에 있어서 i-scan image-enhanced 내시경의 진단적 유용성

이영찬(Young Chan Lee),은영규(Young-Gyu Eun),박일석(Il-Seok Park) 대한두경부종양학회 2018 대한두경부 종양학회지 Vol.34 No.2

Background/Objectives: The aim of this study was to investigate the diagnostic value of i-scan in the differential diagnosis of oral cavity leukoplakia based on visualization of abnormal vascular features. Materials & Methods: Thirty- one patients with oral cavity leukoplakia were enrolled in the study. Images of their oral cavity obtained using conventional white light endoscopy and an i-scan-enhanced endoscopy (Pentax DEFINA EPK-3000 Video Processors, with Pentax VNLJ10) were reviewed. The microvascular features of the lesions and vascular changes were analyzed and the results were compared with the histopathologic diagnosis. Results: Among the 31 oral cavity leukoplakia patients, 8 (25.8%) patients revealed hyperkeratosis, 10 (31.2%) low-grade dysplasia, 5 (16.2%) high-grade dysplasia and 8 (25.8%) invasive squamous cell carcinoma on histopathologic examination. Using i-scan-enhanced endoscopy, we could found abnormal vascular change with neoplastic neoangiogenesis in most high-grade dysplasia or invasive cancer in oral cavity. (high-grade dysplasia: 4/5 [80.0%], and invasive squamous cell carcinoma: 7/8 [87.5%]). Conclusion: i-scan-enhanced endoscopy could be a useful optical technique for the diagnosis of oral cavity leukoplakia. Our results suggest that i-scan may be a promising diagnostic tool in the early detection of suspected oral mucosal lesion.

인후두 역류 질환: 진단 및 치료

강정욱,은영규,Kang, Jeong Wook,Eun, Young-Gyu 대한후두음성언어의학회 2021 대한후두음성언어의학회지 Vol.32 No.2

Laryngopharyngeal reflux disease (LPRD) is an inflammatory condition of the upper aerodigestive tract mucosa induced by reflux content from stomach. Some of vocal cord diseases are associated with laryngopharyngeal reflux. Because of the pathophysiological features, proton pump inhibitor shows therapeutic effect on some vocal cord diseases. As like that, the gastric reflux contents can make macroscopic or microscopic morphological changes in the upper aerodigestive tract mucosa. Although the pathophysiology of LPRD is relatively clear, clinical diagnosis is still difficult. The diagnosis of LPRD includes objective tests such as 24-hours multichannel intraluminal impedance-pH metry and subjective tests such as questionnaire method. However, the objective verification of reflux is difficult due to invasiveness of the method, and the questionnaire methods have limitations because many symptoms are not specific for LPRD. Moreover, most methods are not fully standardized until now. Despite these limitations, many researchers are struggling to standardize diagnosis and treatment of LPRD, and there are several new achievements recently. Therefore, the purpose of this article is to review the recent literature on the clinical presentation, diagnosis, and treatment of LPRD, and to systematize our knowledge.

성대 낭종 내부에 발생한 후두 편평세포암종

이선규,송민정,은영규,이영찬,Lee, Seon-Gyu,Song, Min Jeong,Eun, Young-Gyu,Lee, Young Chan 대한후두음성언어의학회 2021 대한후두음성언어의학회지 Vol.32 No.1

More than half of patients presenting with hoarseness show benign vocal cord changes. However, in rare cases with benign mucosal lesions, it can be diagnosed as a malignant disease after histopathological examination. A 53-year-old man with a 30-pack-year smoking history was admitted for the evaluation of hoarseness, and using a laryngoscope, an enclosed, sac-like cystic lesion was detected on the midpoint of the right true vocal cord. The cystic lesion was deemed to be an intracordal cyst and treated with laryngeal microsurgery. However, pathological findings showed squamous cell carcinoma of the larynx arising in the intracordal cyst, which is exceptionally rare. Therefore, even if a benign lesion is initially suspected, a biopsy must be performed on a patient with smoking history to confirm the diagnosis. In conclusion, we report a case of squamous cell carcinoma of the larynx arising in the intracordal cyst.

칼집형 기관을 가진 성문하부암 환자 1례

강정욱,정아라,은영규,이영찬,Kang, Jeong Wook,Jung, Ah Ra,Eun, Young-Gyu,Lee, Young Chan 대한후두음성언어의학회 2018 대한후두음성언어의학회지 Vol.29 No.1

"Saber-sheath" trachea is a deformity of lower cervical or intrathoracic trachea. The configuration of the deformity is marked coronal narrowing associated with sagittal widening. This deformity is associated with chronic obstructive pulmonary disease. We report a case of patient with saber-sheath who underwent total laryngectomy. Although the patient had no tracheal collapse after the total laryngectomy, crusted discharge was increased. Diagnosis of the saber-sheath trachea, possible causes, and clinical implications are discussed.

소아에서 발생한 연구개 점액표피양 종양 1례

정 훈(Hoon Jung),은영규(Young Gyu Eun),권기환(Kee Hwan Kwon) 대한두경부종양학회 2008 대한두경부 종양학회지 Vol.24 No.2

The purpose of this paper is to review our experience with mucoepidermoid carcinoma(MEC), a rare tumour in minor salivary glands, in a paediatric patients. 15-year-old boy was noted to have a irregular round mass appearing atthe soft palate just to the right of the mid-line. A computed tomographic(CT) scan showed a palatal mass limited to soft palate with no bony erosion . The lesion was curetted and debulked. Pathology was reported as an intermediate-grade mucoepidermoid carcinoma, and the patient was consider-ed to radiation therapy institution for further treatment. To date, patients remain free of disease. Wide local excision is the treatment of choice for low to intermediate grade MEC of the minor salivary glands in pae-diatric patients.

급성 후두개염 환자의 Scope Classification에 따른 특성 비교

김경휘,정용기,김명구,은영규,Kim, Kyoung Hwi,Jung, Yong Gi,Kim, Myung Gu,Eun, Young Gyu 대한기관식도과학회 2011 大韓氣管食道科學會誌 Vol.17 No.2

Background and Objectives Scope classification is designed to classify acute epiglottitis according to laryngoscopic findings. There is no report about the utility of classification; the difference between the diagnosis and the prognosis by the Scope classification was not found. The aim of this study was to evaluate the utility of Scope classification in patients with acute epiglottitis. Subject and Method 127 patients who had been admitted to our hospital were diagnosed with acute epiglottitis. The patients were classified by the Scope classification. We compared demographic characteristics, clinical symptoms and signs, laboratory findings, and clinical course among the patient groups and divided the results according to the Scope classification. Results There are no significant differences among the groups in demographic characteristics, clinical symptoms and signs, laboratory findings, and clinical course. Conclusion The Scope classification of acute epiglottitis does not seem to be a method to evaluate the severity of acute epiglottitis. Thus, we need to develop multidisciplinary approaches for acute epiglottitis.

악하선에 발생한 종양 혈전을 동반한 다형선종유래 선암종

권 철(Chul Kwon),박철언(Choel Eon Park),신일호(Il Ho Shin),은영규(Young Gyu Eun),권기환(Kee Hwan Kwon) 대한두경부종양학회 2010 대한두경부 종양학회지 Vol.26 No.2

Carcinoma ex pleomorphic adenoma is rare, aggressive, poorly understood malignancy that occurs in the salivary glands. The patient was 70-year-old male presenting ovoid elevated submandibular mass that has been present for 30 years and rapid growing for 6 months. The initial cytologic finding by fine needle aspiration biopsy showed highly malignant cells and the radiologic finding revealed a 3.6×3.7×4.8cm sized mass with cervical lymphadenopathy. After wide excision of submandibular gland and modified radical neck dissection, the histologic examination revealed that tumor was composed partly of a benign pleomorphic adenoma and partly of an adenocarcinoma component with areas of calcification and frequent angiolymphatic invasion. We present a rare case of adenocarcinoma ex pleomorphic adenoma with tumor thrombus in the submandibular gland.