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악하선에 발생한 종양 혈전을 동반한 다형선종유래 선암종
권 철(Chul Kwon),박철언(Choel Eon Park),신일호(Il Ho Shin),은영규(Young Gyu Eun),권기환(Kee Hwan Kwon) 대한두경부종양학회 2010 대한두경부 종양학회지 Vol.26 No.2
Carcinoma ex pleomorphic adenoma is rare, aggressive, poorly understood malignancy that occurs in the salivary glands. The patient was 70-year-old male presenting ovoid elevated submandibular mass that has been present for 30 years and rapid growing for 6 months. The initial cytologic finding by fine needle aspiration biopsy showed highly malignant cells and the radiologic finding revealed a 3.6×3.7×4.8cm sized mass with cervical lymphadenopathy. After wide excision of submandibular gland and modified radical neck dissection, the histologic examination revealed that tumor was composed partly of a benign pleomorphic adenoma and partly of an adenocarcinoma component with areas of calcification and frequent angiolymphatic invasion. We present a rare case of adenocarcinoma ex pleomorphic adenoma with tumor thrombus in the submandibular gland.