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기분 장애 소아 청소년 환자에서 자살 행동, 공격 행동과 인지기능과의 관계
윤희준(Hee Joon Yoon),오윤혜(Yunhye Oh),정유숙(Yoo Sook Joung) 대한소아청소년정신의학회 2016 소아청소년정신의학 Vol.27 No.1
Objectives: The aim of this study was to examine the association between current suicidal or violent behavior and deficits of specific neurocognitive variables in child and adolescent inpatient samples diagnosed with mood disorder. Methods: A retrospective review of the charts of mood disorder patients hospitalized at Samsung Medical Center between April 2004 and April 2015 was conducted. Child and adolescent patients aged between 10 and 18 years old and those who finished neurocognitive function testing during their hospitalization were included. Among them patients whose full scale IQ was between 85 and 115 were selected (N=111). Participants were first divided into two age-groups–group Y (10≤age≤15, N=54) and group O (16≤age≤18, N=57)–because neurocognitive function test tools were different according to age [Wechsler Intelligence Scale for Children (WISC) for 10 to 15-year-old patients, Wechsler Adult Intelligence Scale (WAIS) for 16 to 18-year-old patients]. They were then divided according to their suicidal or violent behavior–non suicidal/violent group (NG), suicidal group (SG), violent group (VG), and both suicidal/violent group (BG). The Child Behavior Checklist (CBCL) was checked for measurement of participants’ behavior and the Gordon Diagnostic System was checked for measurement of their attention efficiency. Kruskal-Wallis Test and Tukey test was used to determine the differences in neurocognitive function between groups. Results: O-SG patients showed lower scores on the comprehension subscale of WAIS-III than O-NG patients (χ<SUP>2</SUP>=8.454, p=.015). O-VG patients showed lower scores on the block design subscales of WAIS than O-SG patients (χ<SUP>2</SUP>=7.496, p=.024). Y-VG patients showed higher scores in aggressive behavior, externalizing problems, and total problems scores of CBCL. Conclusion: This study showed relationship between specific neurocognitive deficits and suicidal or violent behavior. These relationships were significant in relatively older adolescents.
주의력결핍 과잉행동장애 환아들의 인지 행동적 특성과 정량 뇌파와의 관계 : 후향적 단면 연구
오수환(Soohwan Oh),정유숙(Yoo Sook Joung),윤희준(Hee Joon Yoon),이동익(Dong Ik Lee),김병욱(Byung Wook Kim),박정아(Jung Ah Park),이서지(Suzie Lee),이빛나(Bitna Lee) 대한신경정신의학회 2018 신경정신의학 Vol.57 No.3
Objective This study examined the association between the wave form in quantitative electroencephalography (QEEG) and the cognitive and behavioral characteristics measured by the Korean version of Wechsler Intelligence Scale for Children 4th edition (K-WISC-IV), Korean version of the attention deficit/hyperactivity disorder Rating Scale (K-ARS), and Korean version of Child Behavior Checklist (K-CBCL) in children diagnosed with ADHD. Method A retrospective cross-sectional study was performed on children aged 8 to 13 years, who were diagnosed with ADHD at Samsung Medical Center from November 2011 to March 2017. A total of 57 ADHD children were selected by a medical chart review. Their QEEG findings and psychological test results, including K-WISC-IV, K-CBCL, and K-ARS (n=42), were collected. The QEEG was analyzed by the ranges of Hz: delta (1 - 4 Hz), theta (4 - 8 Hz), alpha (8 - 12 Hz), and beta (12 - 25 Hz) and transformed to the z-scored relative power. The collected data were analyzed using Pearson and Partial correlation analysis. Results The Letter-Number Sequencing scores of K-WISC was positively correlated with fronto- central alpha. The hyperactivity/impulsivity scores of K-ARS were positively correlated with the theta/beta ratio. Among the items of K-CBCL, social immaturity was positively correlated with delta and theta, and negatively correlated with alpha. Social competence was negatively correlated delta and theta, and positively correlated with alpha. Conclusion These results suggest that the resting state QEEG results of children with ADHD may reflect their cognitive and behavioral characteristics, especially in working memory/executive function, hyperactivity/impulsivity, and sociality.