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이달의 X-선 : 4년간 크기가 일정한 고립성 폐결절이 선암으로 진단된 1예
윤병갑 ( Byeong Kab Yoon ),김은주 ( Eun Ju Kim ),김덕인 ( Deok In Kim ),이금호 ( Kum Ho Lee ),류정선 ( Jeong Seon Ryu ),곽승민 ( Seung Min Kwak ),이홍렬 ( Hong Lyeol Lee ),조재화 ( Jae Hwa Cho ),김루시아 ( Lu Ci A Kim ),이경희 ( Ky 대한결핵 및 호흡기학회 2005 Tuberculosis and Respiratory Diseases Vol.59 No.3
리도카인 아나필락시스 환자에서 경직 기관지내시경술을 통해 기도 암종을 진단한
윤병갑 ( Byeong Kab Yoon ),반희정 ( Hee Jung Ban ),권용수 ( Yong Soo Kwon ),오인재 ( In Jae Oh ),김규식 ( Kyu Sik Kim ),김유일 ( Yu Il Kim ),임성철 ( Sung Chul Lim ),김영철 ( Young Chul Kim ),송상윤 ( Sang Yoon Song ) 대한결핵 및 호흡기학회 2009 Tuberculosis and Respiratory Diseases Vol.67 No.2
The majority of flexible bronchoscopies are performed under topical anesthesia with lidocaine being the most commonly used agent. Anaphylaxis rarely occurs after local administration of lidocaine, but can be a fatal complication. We experienced a case of unexpected anaphylaxis. A 66-year-old woman was scheduled for flexible bronchoscopy to evaluate a tracheal mass and stenosis. The oral and nasal mucosa were pretreated with lidocaine. About 2∼3 minutes later, the patient developed hypotension and we treated for anaphylaxis in the emergency room. Then, we decided to perform rigid bronchoscopy in this patient, under conditions of general anesthesia. A rigid bronchoscopy was performed in this patient, safely and successfully. The tracheal mass was determined to be squamous cell carcinoma.
김덕인 ( Deok In Kim ),김형렬 ( Hyoung Ryoul Kim ),박해심 ( Hae Sim Park ),박신구 ( Sin Gu Park ),임종한 ( Jong Han Leem ),노재훈 ( Jae Hoon Roh ),김정구 ( Jeong Goo Kim ),윤병갑 ( Byeong Kab Yoon ),김철우 ( Cheol Woo Kim ) 대한천식알레르기학회 2005 천식 및 알레르기 Vol.25 No.4
Background: Toluene diisocyanate (TDI) is known to be the most common cause of occupational asthma (OA) in Korea. Although TDI can elicit humoral immune responses including specific-IgE (sIgE) and specific-IgG (sIgG) responses, the exact role of these immune responses has not been clearly clarified yet. Objective: This study was carried out to estimate the prevalence of TDI-induced OA, and to evaluate the clinical significance of TDI-related humoral immune responses in currently TDI-exposed workers. Method: Questionnaire interview for respiratory symptoms was conducted to 170 workers with direct exposure to TDI (exposed group). After screening survey, workers with suspected occupational asthma were selected for methacholine and TDI bronchial provocation tests (BPTs). Serum sIgG and sIgE antibodies to TDI-HSA conjugate, and sIgG to cytokeratin (CK) 8, 18, and 19 were detected by enzyme-linked immunosorbent assay in 170 exposed workers, and compared with 61 unexposed workers in the same workplace (unexposed group) and 75 unexposed healthy controls(healthy control group). Result: Eleven (6.9%) among 170 workers complained symptoms of OA, and 7 of 11 symptomatic workers showed positive airway hyperresponsiveness to methacholine (4.1%). One worker with spray-painting job was confirmed as having TDI-induced asthma by showing positive responses to both methacholine and TDI BPTs. The prevalence of sIgG to TDI-HSA conjugate was significantly higher in TDI-exposed workers (10.1%) than in unexposed workers (0%) and healthy control (2.7%). However, no significant difference was noted between symptomatic (18.2%) and asymptomatic workers (9.5%) among the exposed group. The prevalences of sIgE to TDI-HSA conjugate and sIgG to CK 8, 18, 19 were not significantly different between the three groups. Conclusion: The prevalence of TDI-induced OA was noted to 0.58% in the current working environments. The clinical significance of TDI-induced humoral immune responses may be clarified by further prospective studies. (Korean J Asthma Allergy Clin Immunol 2005;25:276-283)
조계중 ( Gye Jung Cho ),임정환 ( Jung Hwan Lim ),채동렬 ( Dong Ryeol Chae ),지수영 ( Su Young Chi ),반희정 ( Hee Jung Ban ),윤병갑 ( Byeong Kab Yoon ),권용수 ( Yong Soo Kwon ),오인재 ( In Jae Oh ),김규식 ( Kyu Sik Kim ),김유일 ( Y 대한결핵 및 호흡기학회 2009 Tuberculosis and Respiratory Diseases Vol.66 No.6
Paragonimiasis is a parasitic infection that occurs following the ingestion of infectious Paragonimus metacercariae, which occurs as a result of eating raw or undercooked freshwater crabs or crayfish. Pulmonary paragonimiasis is the most common clinical manifestation of this infection. Human paragonimiasis occurs sporadically. We experienced a case of pulmonary paragonimiasis in a 35-year-old woman with left lower chest pain. The patient had hypereosinophilia and a pleural effusion. The diagnosis was confirmed by positive ELISA (Enzyme-linked immunosorbent assay) that detected Paragonimiasis westermani antibody in the serum. We treated the patient with praziquantel for two days at a daily dosage of 75 mg/kg. Left pleuritic pain and pleural effusion improved after treatment. However, similar symptoms and pleural effusion developed recurrently for the first 3 courses of treatment with praziquantel. Upon the fourth round of treatment, the patient made a full recovery.