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RISS 인기검색어
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- 저자 : 이승우 ( Seoung Woo Lee ) (검색결과 87 건)
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이승우(Lee Seoung-Woo),김재철(Kim Jae-Chul),이동훈(Lee Dong-Hoon),추돈호(Choo Don-Ho) 한국철도학회 2008 한국철도학회 학술발표대회논문집 Vol.- No.-
As the improvements of service quality is becoming an important issue the, interior noise level of a train is an important factor of comfortable ride. To reduce the interior noise level, noise sources of the train need to be removed. However, in case with a structure of large scale and multiple noise sources, an estimation of influences of major noise sources, with indentification of its traveling paths needs to be performed. In current state, to improve the interior noise reduction, consideration of sound transmission loss of the train body prior to manufacturing is usually performed. In this study, the sound transmission loss of the train body of new model train of seoul metro"s line no.2 under test opeation is measured and modeling of the train body is performed. And train interior noise is predicted using the measured values.
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말기 신부전 환자에서 동맥경화증의 임상적 지표와 고해상도 B모드 경동맥 초음파 소견의 상관성
이승우(Seoung Woo Lee),김문재(Moon Jae Kim),송준호(Joon Ho Song),김경아(Gyeong A Kim),이창근(Chang Keun Lee),박경수(Kyeong Soo Park) 대한신장학회 2000 Kidney Research and Clinical Practice Vol.19 No.2
N/A Atherosclerotic cardiovascular disease(AVD) is a major cause of the mortality and morbidity in end-stage renal disease(ESRD) patients undergoing chronic dialysis therapy. The factors such as lipopretein metabolism abnormality, diabetes, hypertension, hyperhomocysteinemia and oxidative stress have been implicated as underlying causes related AVD. Malnutrition, chronic inflammation, increased oxidative stress, hyperparathyroidism and its related lipoprotein abnormalities are suggested to accelerate AVD in ESRD patients. High-resolution B-mode ultrasono-graphy has been used to evaluate atherosclerotic change in carotid artery in a number of epidemiologic or clinical studies because of its non-invasive advantage and proven effects in predicting AVD or cardiovascular mortality. Using high-resolution B-mode sonography, we evaluated the presence of plaque and carotid intima-media area(cIM area), which is known to be a good predictor of athero-sclerosis. We compared and analyzed those sono-graphic findings according to a number of selected clinical and laboratory factors. Study subjects were 27 stable ESRD patient re-ceiving hemodialysis(HD) or chronic ambulatory pe-ritoneal dialysis(CAPD) at least over 24 months. The patients with present or past coronary, cerebral or peripheral vascular disease, history of anti-platelet agents or age over 70 years were excluded. Nine HD and 18 CAPD patients were included and mean age was 52.1±2.6 years and number of male and female patients were sixteen and eleven. Among many factors, sex, age, dialysis duration, diabetes, smoking history, blood pressure, body mass index, albumin, creatinine, high-density lipoprotein, trigly-ceride, C-reactive protein, total calcium, phosphorus, intact-parathyroidid hormone were selected and analyzed for their correlation with carotid sonograpic findings. 1) Mean cIM area of all patients was 15.4±0.7 mm². cIM area was significantly increased in CAPD patients compared to HD patients(16.5±1.2 vs 14.9± 0.9mm², p<0.05). Atherosclerotic plaques were found in 48.1% and bilateral lesion was found in 18.5% of all patients. The incidence of the plaque was 42.1% in HD and 55.6% in CAPD patients. 2) cIM area was more significantly increased in male than female(16.7±0.8 vs 13.6±1.2mm²), in dia- betes than non-diabetes(16.4±0.8 vs 14.7±l.lmm²) and in smoker than non-smoker(18.8±0.7 vs 12.8±0.7mm², p<0.05). It was also significantly inereased in patients with body mass index more than 2.3kg/ m(18.3±1.1 vs 14.6±0.8mm), systolic blood pres-sure more than 14mmHg(16.6±0.7 vs 13.0+1.2mm) and C-reactive pretein more than 0.5 mg/dL(18.9±1.5 vs 14.2±0.77mm²p<0.05). Among those factors, age, systolic blood pressure, body mass index and C-reactive protein were proven to positively correlate to cIM area with statistical significance(p<0.05). Even though cIM area was increased in pa-tients with high serum parathyroid hormone, high total cholesterol and triglyceride and low high-den-sity lipoprotein level, no statistical significances were found in these factors. 3) In comparison of each factor according to the presence of the plaque, age and the presence of dia-betes were proven to be significantly different bet-ween patients without the plaque and with the plaque(45.7±2.7 vs 59.5±3.8 year, 33.3% vs 53.8%, respectively, p<0.05). Systolic blood pressure and C- reactive protein were increased in patients with the plaque but no statistical significance was shown. In conclusions, we found that old age, male sex, presence of diabetes, smoking history, high systolic blood pressure, increased body mass index and increased C-reactive protein were significantly re-lated to increased cIM area and the plaque was more frequent in old age and diabetes patients using high resolution B-mode ultrasonography. It can be assumed that inflammatory state as reflected by C-reactive protein would be more related with atherosclerosis in ESRD patients than such as nu-tritional state, parathyro
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신증후출혈열 환자에서 경구 Ribavirin 의 투여 효과
이승우(Seoung Woo Lee),민현조(Hyun Zo Min) 대한내과학회 1995 대한내과학회지 Vol.48 No.4
N/A (ribavirin group). The control group was 17 patients (15 in 1992, 2 in 1993) and the ribavirin group was 15 patients(all in 1993). No difference was noted between ribavirin and control group at baseline. Results: 1) There were no baseline prognostic factors for mortality in control group. No significant difference in mortality was seen between ribavirin and control group(0/15 vs. 2/17). 2) There were no baseline prognostic factors for hemorrhage in control group. Hemorrhagic complications were significantly decreased in ribavirin group (1/15 vs 7/17, p<0.05)and the ribavirin treatment correlated inversely with the development of hemorrhage(odds ratio 0.16, 95% confidence interval 0.02 to 1.19,p=0.02). By stepwise multiple logistc regression, the variable which better contributed to explain the development of hemorrhagic complications in our patients were ribavirin treatment. 3) No significant differences in duration of febrile, hypotensive and oliguric stage, and skipping of hypotensive and oliguric stage between two groups were seen. But duration of diuretic stage was significantly decreased in ribavirin group(4.7±4.2 vs. 11.4±7.6 days, p<0.05). 4) Mild anemia was observed in most patients and no difference in hematocrit was observed between two groups. Conclusion: Oral ribavirin therapy was effective in the reduction of hemorrhagic complications and duration of diuretic stage. But prospective, double-blind and placebo-controlled study with larger number of patients would be nececsary.
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지속성 외래 복막투석 환자에서의 계절 및 기후 인자와 복막염 발생과의 상관성
이승우(Seoung Woo Lee),김문재(Moon Jae Kim),송준호(Joon Ho Song),김경아(Gyeong A Kim),박영주(Young Joo Park) 대한신장학회 2000 Kidney Research and Clinical Practice Vol.19 No.3
N/A Background: Exit site/tunnel infection causes con-siderable morbidity and technique failure in CAPD patients. We presently use a unique revision method for the treatment of refractory ESl/TI in CAPD patients and mupirocin prophylaxis for high risk patients. Methods : We reviewed one hundred-thirty nine CAPD patients about the ESI/TI from Qctober 1993 to February 1999 at Yeungnam University Hospital. At the beginning of the ESI, we usually started me-dications with rifampicin and ciprofloxacin and then changed the antibiotics according to the sensitivity test. If the ESI had persisted and there were TI symptoms(purulent discharge, abscess lesion around exit site), we performed catheter revision(external cuff shaving, disinfection around tunnel and new exit site on opposit direction) with a combination of proper antibiotics. We applied local mupirocin ointment at the exit site three times per week to the 34 patients who had the risk of ESI starting from October 1998. Results : The total follow-up was 2401 patient months(pt.mon). ESI occurred on 105 occasions in 36 out of 139 patients, and peritonitis occurred on 112 occasions in 67 out of 139 patients. Cumulative incidence of ESI and peritonitis was 1 per 23.0 pt.mon and 1 per 21.6 pt.mon. The most common organism responsible for ESI was Staphylococcus aureus(26 of 54 isolated cases, 43%), followed by Methicillin resistant S. aureus(MRSA)(13 cases, 24%). Seven patients (5: MRSA, 2: Pseudomonas) had to be treated with a revision to control infection. Three patients experienced ESI relapse after revision. One of them im-proved with antibiotics, while another needed a second revision and the remaining required catheter removal due to persistent MRSA infection with re-insertion at the same time. But, there was no more ESI in these 3 patients who were received management to relapse(The mean duration : 14.0 months) The rates of ESI were more reduced after using mupi-rocin than before(l per 12.7 vs 34.0 pt.mon, p<0.01). Conclusion: In summary, revision technique can be regarded as an effective method for refractory ESI/TI before catheter removal. Also local mupirocin ointment can play a significant role in the prevention of ESI.
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말기 신부전증 환자에서 혈액투석과 지속성 외래 복막투석의 시작이 혈압에 미치는 영향
이승우(Seoung Woo Lee),김문재(Moon Jae Kim),송준호(Joon Ho Song),김경아(Gyeong A Kim),박우상(Woo Sang Park),이경주(Kyung Joo Lee) 대한신장학회 2000 Kidney Research and Clinical Practice Vol.19 No.2
N/A Studies describing the effects on blood pressure control by hemodialysis(HD) or continuous amulatory peritoneal dialysis(CAPD) have yielded conflicting results with respect to 24 hour blood pressure control, diurnal variation and blood pressure loads. The aim of the study was to investigate the effect of beginning with HD or CAPD on blood pressure control, diurnal variation and blood pressure loads using ambulatory blood pressure monitoring(ABPM). Twen-ty-seven end-stage renal disease(ESRD) patients(12 on HD and 15 on CAPD) were enrolled into the study. Patients with cardiovascular diseases, erythro-poietin therapy, or severe edema were excluded. ABPM were performed two times before and after the initiation of dialysis. Mean duration of interval between pre- and post-dialysis ABPM were 17±4 days on HD and 13±3 days on CAPD. Daytime and nighttime were defined as the time from 6: 00 AM to 10: 00 PM and from 10: 00 PM to 6: 00 AM of the next day. Systolic and diastolic loads were defined as the percentage of the incidence of systolic and diastolic blood pressure over l% and 90mmHg. Dipper meaning the presence of normal diurnal difference were defined as the differences of daytime- nighttime mean arterial pressure more than 5mmHg. In HD patients, mean systolic and diastolic blood pressure and mean arterial pressure were significantly decreased after dialysis during 24 hour, day- time and nighttime. In CAPD patients, those were also significantly decreased after dialysis during 24 hour, daytime and nighttime(p<0.05). Diurnal differences were increased after CAPD(3.3±9.4 vs 5.4±6.8mmHg) but decreased after HD(4.3±6.2 vs 2.4±10.8mmHg) and the differences of diurnal difference between two groups were significantly different(+2.1±9.0 vs 1.9±8.4mmHg, p<0.05). Proportions of dipper among patients were increased from 16.7 to 66.7% in HD and from 33.3% to 60% in CAPD without statistical significance between two groups. Systolic and diastolic loads were significantly decreased after HD(from 75.0± 38.0 to 37.5±43.8%, from 45.2±29.7 to 12.5±12.8%, respectively, p<0.05) and after CAPD(from 63.1±30,1 to 32.3±27.1%, from 43.4±36.2% to 12.2±16.9%, respectively, p<0.05). Systolic and diastolic loads of daytime and nighttime were significantly decreased after each dialysis modality except nighttime diastolic pressure load in HD. In conclusions, both HD and CAPD improve BP control in ESRD patients. CAPD has more benefit to control of diurnal variations in ESRD patients.
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