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윤경애 ( Kyung Ae Yoon ),김상훈 ( Sang Hoon Kim ),안영민 ( Young Min Ahn ) 대한천식알레르기학회 2011 천식 및 알레르기 Vol.31 No.3
Background: Anaphylaxis is one of the severe adverse drug reactions. Levodropropizine acts as a peripheral antitussive with no action in the central nervous system and thus does not cause side effects, such as constipation and respiratory depression, which can be produced by opioid antitussives, including as codein and its derivatives. Levodropropizine is known to be safe and is commonly used as an antitussive drug. Case History: There has been only 1 report of adult case of anaphylaxis caused by levodroprozine. We experienced the case of a 4 year-old boy who developed recurrent generalized urticaria and confusion after ingestion of levodropropizine. Results: The case was confirmed by skin prick test and oral provocation test. Conclusion: We report one case of anaphylaxis of levodropropizine. Thus levodropropizine should be considered le the causes in patients with drug-induced anaplylaxis. (Korean J Asthma Allergy Clin Immunol 2011;31:219-222)
Mycoplasma pneumoniae 폐렴의 임상적 고찰
오수미(Su Mi Oh),오경영(Kyung Young Oh),윤경애(Kyung Ae Yoon),이선기(Sun Ki Lee),권우진(Woo Jin Kwon),박진(Jin Park),현재호(Jae Ho Hyun),양만규(Man Kyu Yang) 대한소아알레르기호흡기학회(구 대한소아알레르기 및 호흡기학회) 1995 소아알레르기 및 호흡기학회지 Vol.5 No.2
N/A A clinical study was made on 117 cases of Mycoplasnn pneumoniae pneumonia from April 1992 to March 1995. The results were as follows. 1. Out of 117 cases, 57 cases were male, 60 cases were female and high incidence was in the age of 2 to 6 years(76%). Male to female ratio was 1:1.05 and seasonnal distribution showed increased incidence in autumn. 2. Cough(116cases, 99.1%) was the most common clinical symptom and sputum(111cases, 94.9%), rhinorrhea(71cases, 60.7%), fever(69cases, 58.9%) were usual symptom. 3. The most common auscultatory findings were rales (59 cases, 50.4%) and then wheezing (26 cases, 22.2%) and then followed by rhonchi. 4. The most common complication was pleural effusion(5cases). 5. Leukocyte counts in peripheral blood were most common in the range of 5,000-9,999/mm3(58.9%) and showed neutrophilia. Erythrocyte sedimentation rate were higher than 30 mm/hr(73cases, 63.2%). Positive CRP cases were 67 cases(57.3M). 6. Radiologic finding of pulmonary infiltration was the most common in the right lower lobe(30cases, 25.6%), 7. The correlation of cold agglutinin and Mycoplasma Ab was not significant.(r=0.382, p=0.07).
기관지 확장증 환아들의 기관지 과민성에 대한 Roxithromycin 의 효과에 관한 연구
고영률(Young Yull Koh),이명현(Myung Hyun Lee),윤경애(Kyung Ae Yoon),성기웅(Gi Woong Seoung) 대한소아알레르기호흡기학회(구 대한소아알레르기 및 호흡기학회) 1996 소아알레르기 및 호흡기학회지 Vol.6 No.1
N/A Nonspecific bronchial hyperresponsiveness(BHR) is frequently associated with bronchiectasis and may have a role in its pathogenesis. Roxithromycin is a new semisynthetic macrolide antibiotic that also has antiinflammatory activities. This study was designed to see whether roxithromycin could favorably alter bronchial responsiveness in patients with bronehiectasis. Twenty-six children with bronchiectasis were treated for eight weeks with roxithromycin, 4ml/Kg twice a day, orally. To estimate bronchial responsiveness, high-dose methacholine challenge tests were performed before and after treatment. On the dose-response curve to methacholine, PC20 and maximal response, two indices of bronchial responsiveness, were measured. In the methacholine test before roxithromycin treatment, twelve subjects were found to have BHR, defined as a PC20 < 25mg/ml. This group with (+) BHR had significantly higher maximal response than the 14 patients in the (-) BHR group. Changes in FEV1 were not observed during the course of roxithromycin treatment. After eight weeks' treatment the geometric mean of PC20 increased significantly and the mean of maximal response decreased significantly and the mean of maximal response decreased significantly among patients in both groups, as compared with initial values. The magnitude of change in both parameters was statistically significant only in (+) BHR group. Our results indicated that roxithromycin may decrease BHR in the patients with bronchiectasis. This finding suggests that roxithromycin might be a good agent in the long-term management of bronchiectasis, especially when accompanied by BHR.
급성 충수염을 합병한 Henoch - schonlein 자반증
엄영관(Young Kwan Um),오수미(Su Mi Oh),오경영(Kyung Young Oh),윤경애(Kyung Ae Yoon),지제근(Je Geun Chi),최동환(Dong Hwan Choi),김성철(Sung Chung Kim) 대한소아알레르기호흡기학회 1993 소아알레르기 및 호흡기학회지 Vol.3 No.2
We report a case of Henoch-Schonlein purpura that was complicated with an acute perforating appendicitis probably secondary to necrotizing vasculitis involving the appendiceal wall. We stressed the point that acute appendicitis and peritonitis should be considered when the abdominal pain became intractable in the course of Henoch-Schonlein purpura.
오수미(Su Mi Oh),엄영관(Young Kwan Um),윤경애(Kyung Ae Yoon),지제근(Je Geun Chi),홍종협(Jong Hyup Hong),오경영(K . Young Oh) 대한소아알레르기호흡기학회 1994 소아알레르기 및 호흡기학회지 Vol.4 No.2
The immotile cilia syndrome is a clinical syndrome characterized by chronic respiratory tract disease caused by a defect in mucociliary trasport owing to functionally ineffective movemeant of cilia having specific and genetically determined abnormalities. We experienced a case of immotile cilia syndrome in a 13 year-old boy with history of profuse rhinorrhea of 10 years duration. Electron microscopic examination of the respiratory cilia of this patient showed dynein arm defect.