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유병수 ( Byung Su Yoo ) 대한내과학회 2012 대한내과학회지 Vol.82 No.6
Assays for B-type natriuretic peptide (BNP) or N-terminal pro-brain BNP (NTproBNP) BNP are useful diagnostic method for evaluation of patients with dyspnea. And, natriuretic peptide levels have important prognostic value in heart failure. Therefore, measurements of BNP or NT-proBNP, taken together with conventional clinical assessment, may assist in the decision of treatment process. The following brief review summarizes available information concerning clinical significance of BNP or NT-proBNP.
유병수 ( Byung Su Yoo ) 대한내과학회 2011 대한내과학회지 Vol.81 No.6
Optimal treatment of heart failure is important to reduce hospitalization and mortality. In according to recommendation for treatment from major guideline, most patients with HF should be routinely managed with a combination of 3 types of drugs: a diuretic, an ACEI or an ARB, and a beta blocker. The value of these drugs has been established by the results of numerous large-scale clinical trials, and the evidence supporting a central role for their use is compelling. This review is focused on the drug treatment based on the evidence and practical implication. (Korean J Med 2011;81:716-719)
급성 심근경색증 환자에서 조기에 적절한 재관류 요법을 시행받지못한 요인
유병수(Byung Su Yoo),윤정한(Jung Han Yoon),박금수(Keum Soo Park),여경구(Kyung Koo Yoh),조윤경(Yun Kyung Cho),안승찬(Seung Chan Ahn),이용규(Yong Kyu Lee),송광선(Kwang Seon Song),최경훈(Kyung Hoon Choe),이부수(Boo Soo Lee),황성오(Sung 대한내과학회 1995 대한내과학회지 Vol.48 No.6
N/A Objectives: Early application of reperfusion therapy such as thrombolytic agent or direct PTCA is utmost important to amximize the efficacy of reperfusion therapy in patients with aute myocardial infarction. However, early adequate reperfusion thearpy was given only in 15% to 36% pf patients with acute myocardial infarction and substantial patients were not benefited from reperfusion therapy, Therefore, we performed these study to evaluate the reasons for which patients with acute myocardial infarction cannot receive an adequate reperfusion therapy. Methods: We analyzed the initial electrocardiogram and various time delays from chest pain onset time, first hospital arrival time, transfer time, ER arrival time, and door to reperfusion time in 138 patients with acute myocardial infarction from Jan. 1991 to Oct. 1993 admitted to Wonju Christian Hospital. Patients were grouped as reperfusion group(n=55) who had reperfusion therapy such as thrombolytic trial or direct PTCA and conservative grou who had not received reperfusion therapy(n= 83). Results: 1) Eighty-three cases(60.1%) did not received an adequate reperfusion therapy. 2) Hospital arrival time of patients was 237±162min and 786±615min in reperfusion and conservative group(p<0.05) respectively. Patient time delay was 103±98min and 439±511min, first hospital time delay, 93±78min and 333±482min, and transfer time, 81±59min and 105±64min in reperfusion and conservative group respectively(p<0.05). Only 4.8% of patients was transferred from first hospital after reperfusion therapy. 3) Patient time delay was the most common reason of not receiving reperfusion therapy, and time delay and lack of adequate reperfusion therapy at the first hospital inspite of early arrival were the second place. Other reasons were contraindication to lytic therapy(4 cases), definite Q wave MI(11 cases), inconclusive EKG(4 cases), and delay in therapy(4 cases). Conclusion: The most common reason of not receiving reperfusion therapy was patient delay in seeking medical care(45.8%) and time delay at first hospital in 22 cases(26.5%). To maximize the effectiveness of reperfusion therapy, it is important to shorten hospital arrival time delay and widespread use of reperfusion therapy at first hospital is recommeded.
김세은 ( Se-eun Kim ),유병수 ( Byung-su Yoo ) 대한내과학회 2021 대한내과학회지 Vol.96 No.2
Diabetes is one of the important risk factors in cardiovascular disease associated with atherosclerosis, and cardiovascular disease is the leading cause of death in patients with diabetes mellitus. Recent randomized placebo-controlled cardiovascular outcome trials of all new antidiabetic drugs have linked SGLT-2 inhibitors and GLP1-agonists to not only increased cardiovascular stability but significant reduction of cardiovascular disease. These results have led to preferential selection of the most effective and beneficial antidiabetic drugs with the evidence of cardiovascular safety and efficacy. Herein, we address cardiovascular stability and the effectiveness of antidiabetic drugs, focusing on recently developed ones. (Korean J Med 2021;96:85-91)
Steam plasma를 이용한 폐PP수지(Polypropylene Resin)의 가스화 처리연구(Ⅱ)
박현서(Hyun-Seo Park),유병수(Byung-Su Yoo),권설희(Seol-Hee Kwon),이 훈(Hun Lee),김수영(Su-Yeong Kim),신은지(Eun-Ji Sin) 한국열환경공학회 2012 한국열환경공학회 학술대회지 Vol.2012 No.-
플라스틱은 뛰어난 특성과 경제성 때문에 일상생활은 물론 관련 산업계에서 유용하게 사용되기 때문에 플라스틱 원료 생산량이 연간 1천만 톤에 이르는 세계 제 5위 생산국이 되었으며 1인당 플라스틱 사용량도 연간 100kg이 넘는 나라가 되었다. 플라스틱 물품의 생산과 소비가 빠르게 증가함으로써 빚어진 부산물로 폐플라스틱 처리 문제에 대해 대기오염, 수질오염과 함께 제 3의 산업오염이라 한다. 이러한 폐플라스틱의 주 처리 방법은 소각과 매립인데 이로 인해 다양한 환경오염으로 사회적 문제가 되고있다. 이러한 문제점들을 해결함과 동시에 좀 더 합리적이고 효율적인 플라스틱의 처리, 처분을 위한 Recycling 기술의 개발이 필요한 시점이다. Recycling 기술의 개발의 목적은 자원의 순환적인 이용에 의해 석유 등 제한된 천연자원의 소비를 억제하고 환경에 대한 부하를 최대한 줄이는 것이다. 또한 경제성을 고려한 실용적인 측면에서도 고려를 해야 하며 이러한 조건들을 동시에 만족시키는 Steam plasma torch를 이용한 가스화 기술은 전 세계적으로 다양한 방법으로 진행되고 있는 실정이다. 이 연구는 Steam plasma torch를 이용하여 PP(Polypropylene resin) 수지를 가스화 기술로 syn-gas(H2+CO)를 80%이상 제조 하여 고효율 에너지화를 목적으로 연구를 진행하였다.