Extended Depth of Focus 알고리듬 파라메타 초기설정에 관한 연구

유경무(Kyungmoo Yoo),주효남(Hyonam Joo),김준식(Joonseek Kim),박덕천(Duckchun Park),최인호(Inho Choi) 한국방송·미디어공학회 2012 방송공학회논문지 Vol.17 No.4

추골기저동맥 일과성 허혈발작에서 뇌간청각유발전위변화에 영향을 미치는 인자

박영혁,유봉구,김광수,유경무,Park, Young Hyuk,Yoo, Bong Goo,Kim, Kwang Soo,Yoo, Kyung Moo 대한임상신경생리학회 2000 Annals of Clinical Neurophysiology Vol.2 No.2

Background and Purpose : Brainstem auditory evoked potentials(BAEPs) are responses of the brainstem by auditory stimulation. Vertebrobasilar transient ischemic attacks is the disease that occurs by insufficient circulation in the region of brainstem. The purpose of this study is to know the factors influencing the changes of BAEPs in vertebrobasilar transient ischemic attacks. Methods : The subject of study was 96 patients diagnosed as vertebrobasilar transient ischemic attacks. Patients were divided into two groups according to the BAEPs findings. Their age, sex, presence of hypertension, diabetes, hyperlipidemia, heart disease, neurologic findings, previous stroke, previous vertebrobasilar transient ischemic attacks, smoking and alcohol drinking, and time period between symptom onset and testing were compared. Results : There were no significant differences in age, sex, and presence of hypertension, diabetes, hyperlipidemia, heart disease, previous stroke history, previous vertebrobasilar transient ischemic attack, smoking, and alcohol drinking between two groups. The presence of abnormal neurologic findings in the first examination and time period between symptom onset and testing were significantly different between normal BAEPs group and abnormal BAEPs one(P<0.05). Conclusions : The factors influencing the changes of BAEPs were presence of abnormal neurologic findings and time period between symptom onset and testing. These findings suggest that BAEPs test should be performed in acute stage of ischemic attack.

뇌경색에 의한 편측부전마비에서 자기운동유발전위의 변동

이주호,박영혁,김광수,유경무,Lee, Ju Ho,Park, Young Huk,Kim, Kwang Soo,Yoo, Kyung Moo 대한임상신경생리학회 1999 Annals of Clinical Neurophysiology Vol.1 No.2

Background and Objectives : The Motor evoked potentials (MEP) study may be useful in the evaluation of the degree of impairment in the motor nervous system and in the determination of the prognosis. The purpose of this study is to evaluate the status of central nervous system in acute and subacute state of cerebral ischemia by comparing the changes of MEP in the initial and follow-up study. Methods : Twenty patients with hemiparesis caused by ischemic stroke were recruited for this study. We tested MEP within 7 days and followed-up after 14 days after symptom onset. The cerebral motor cortex area, cervical area for upper extremity and lumbar area for lower extremity were stimulated by transmagnetic stimulator. The central motor conduction time(CMCT) was measured with the difference in MEP caused by stimulating the vertical area and spinal area. The CMCT of hemiparetic patients were classified into three groups-normal, delayed, and no evoked MEP groups. Results : The CMCT in hemiparetic side of acute ischemic stroke patients were singnificantly delayed (P < 0.05) compared with the control group. The CMCT of hemiparetic side in the follow-up study showed no sinificantly difference in comparison to the control group. The prognosis of motor improvement was better in the groups of delayed MEP than the groups of no evoked MEP. Conclusion : The CMCT of hemiparetic and contralateral sides were delayed in acute ischemic stroke, compared with control group and were returned to normal boundaries in subacute state. But in the most cases with no MEP response in the initial study, also showed no MEP response in the follow-up study. The recovery occurred in the subacute state in cases with mild hemiparesis, whereas recovery did not occur in the subacute stage in case with severe hemiparesis.

류마티스 관절염환자에 동반된 불현성 말초신경병증

김진구 ( Jin Gu Kim ),정연순 ( Yeon Soon Jung ),유경무 ( Kyung Moo Yoo ),홍관표 ( Kwan Pyo Hong ) 대한류마티스학회 2000 대한류마티스학회지 Vol.7 No.2

Objective: Symptomatic neuropathy is uncommon in rheumatoid arthritis (RA) but, compression neuropathy and vascular neuropathy were reported in longstanding RA. To investigate the occurrence of electrophysiologically evident peripheral nerve involvement in RA patients without a clinical manifestation of peripheral nerve involvement, we studied nerve conduction velocity study (NCV) in RA patients without symptomatic neuropathy. Methods: Twenty-five RA patients were evaluated neurological examination and by NCV. We compared clinical parameters between electrophysiologic positive group and negative group. Results: There was no patient who had neurologic symptoms or signs of peripheral involvement. Eleven patients (44%) of all exhibited NCV findings consistent with distal symmetrical sensorimotor polyneuropathy, 5 patients (20%) had entrapment neuropathy, 2 patients (8%) showed distal symmetrical sensory polyneuropathy, 1 patient (4%) had digital neuropathy, and 6 patients (24%) had normal NCV. Conclusion: Patients with RA may have electrophysiologic peripheral nerve damage, even in the absence of clinical evidence of peripheral nerve involvement. There was no correlation with any clinical parameters. The inclusion of electrophysiologic examination of the RA patients is recommended in routine diagnostic procedures.

삼투질농도가 Ethanol 흡수(吸收)에 미치는 효과

김신윤(Kim, Shin-Yoon),김병국(Kim, Byoung-Guk),유경무(Yoo, Kyoung-Mu),김형진(Kim, Hyeong-Jin),박재식(Park, Jae-Sik),황수관(Hwang, Soo-Kwan) 대한생리학회 1981 대한생리학회지 Vol.15 No.1

In the present study, an effort was directed to elucidate the effect of osmolality on the absorption of ethanol in rabbits. A single dose of 13.67 ml(2. 16 gm ethanol/kg BW) of hypo-, iso-hyphen and hypertonic ethanol per kg BW was administered into the stomach to albino rabbits and the experiment was performed at 30 th, 60 th and 120 th minute. The blood ethanol level was determined by the method of Williams et al, and hematocrit(Hct) was determined by the conventional Hct centrifuge and reader. The results are summarized as follow. The blood ethanol level showed the highest value at 60 min after the ethanol ingestion in the hypo- and isotonic groups, 171.3±13.3 mg% and 204.5±23.0 mg% , respectively, but in the hypertonic group, the highest value was observed at 120min after the ingestion. The absorption rate of ethanol between 0 to 30 min after the ingestion of hypo- and isotonic ethanol was 88.54±12.04 and 94.73±8.33 mg/min , respectively, but a decreased value of 44.72±6.69 mg/min was noted after hypertonic ethanol ingestion comparing with hypo- and isotonic groups, The Hct value after hypo- and isotonic ethanol ingestion was decreased at 30 min but returned to the control level at 120 min. In contrast with hypo- and isotonic ethanol ingestion, hypertonic ethanol ingestion produced an increase of the Hct value at 30 min and returned to the control level at 120 min. The heart rate was increased but the respiratory rate was decreased after ethanol ingestion regardless of the osmolality.

파상풍 환자에 대한 임상적 고찰

유경무,유봉구 고신대학교 의학부 1993 高神大學校 醫學部 論文集 Vol.9 No.2

A clinical study was made of 19 cases of tetanus from June 1977 to May 1993 at Kosin Medical College Hospital and the following results were obtained. 1. The ratio of male to female was 1.1: 1 and there was no relationship between sex and mortality. 2. The site of injury was chiefly located in the lower extremity in 8 cases(42.1 %) with highest mortality (62.5%). 3. There was a close relationship between the incubation period and mortality. 4. Also there was a close relationship between the onset time and mortality. 5. The mean duration of admission was 21.1 days and 6 of deaths coccurred in less than 7 days. 6. There was more effective result in the penicillin with metronidazole group than the penicillin group. 7. There was very low mortality in the TIG(human tetanus immune globulin) group than the TAT(tetanus antitoxin) group.

운동신경원성질환을 동반한 산발성 크로이츠펠트-야곱병 1예

유봉구,김광수,유경무 대한치매학회 2003 Dementia and Neurocognitive Disorders Vol.2 No.1

Dementia with motor neuron disease includes frontotemporal dementia with motor neuron disease, amyotrophic Creuzfeldt-Jakob disease, Parkinson-amyotrophic lateral sclerosis-dementia complex, familial amyotrophic lateral sclerosis, and hereditary spastic paraparesis. A 54-years-old man presented with a eight month history of rapidly progressive dementia. Progressively more severe dementia was accompanied by muscle wasting and visible fasciculations. Cerebrospinal fluid showed the 14-3-3 protein. Brain MRI revealed mild diffuse atrophy in both frontal, temporal and parietal lobes. He died 9 months after onset of the disease. We report a patient with sporadic Creuzfeldt-Jakob disease with motor neuron disease.

뇌 자기공명영상에서 가역성 뇌병변을 보인 임신자간 1례

유봉구,윤성민,김광수,유경무 고신대학교 의학부 1995 高神大學校 醫學部 論文集 Vol.10 No.2

The authors report a case of eclampsia in which brain MR examination showed reversible brain abnormalities. A 27-year-old woman with eclamptic convulsion during her 36th week of gestation was presented. Initial MRI (Magnetic Resonance Imaging) revealed multiple hyperintense areas through the cerebrum, cerebellum and brain stem, most likely related with cerebral ischemia and/or edema. Despite these severe and diffuse lesions, follow-up MRI's obstained 8 days after admission and 2 months after dischage demonstrated marked and complete resolution of brain lesions, respectively.

各種 局部的 神經病變에서의 正中神經 短潛伏期體感覺誘發電位反應

劉京武,李相度,朴永春 啓明大學校 醫科大學 1987 계명의대학술지 Vol.6 No.2

A number of short-latency somatosensory evoked potential (SEP) studies on various localized neurological lesions has been reported recently to delineate neural generators of each SEP waves. However, their localizing value remains to be elucidated since their specific neural origins still have been debated. We studied median SEP abnormalities in 53 patients with well localized neurological lesions which were diagnosed clinically and by laboratory examinations (EMGs or brain CT scans). In 9 patients with polyneuropathy, latencies of N9, N13 and N19 were delayed, and amplitudes of N9 and N13 were decreased. Whereas amplitude of N19 and P23 and latency of P23 were normal. In 5 patients with brachial plexus injury, there were absence of N9 and subsequent SEP waves, or delayed latencies of N9 and N13 with low amplitudes. In 3 patients with cervical cord injury, there was normal N9. Whereas N13, N19 and P23 were absent or low amplitudes with normal latencies. In 3 patients with brainstem lesions (2 infarction and 1 metastatic tumor), there were normal N9 and N13 latencies, low amplitude of N13 and absent contralateral N19 and P23. In 19 patients with thalamic lesions(17 hemorrhage, 1 infarction and 1 metastaic tumor), there were normal N19 and N13,and absent N19 and P23 contralateral to the side of stimulation in cases of sensory deficit, whereas delayed or low amplitude of contralateral N19 and/or P23 in cases of mild sensory deficit. In 6 patients with putaminal hemorrhage. there were normal N9 and N13 and absent contral-ateral N19 and P23 in cases of sensory deficit, whereas low amplitude of N19 and P23 in cases without sensory deficit. And in 8 patient with well localized parietal infarction, there were also normal N9 and N13 , and absent contralateral N19 and P23 or delayed latency of P23 in cases of sensory deficit, whereas were delayed latency of P23 or low amplitude of N19 and P23 in cases without sensory deficit. In above SEP findings in well localized neurological lesions we propose the neural generator of N9 is near brachial plexus, N13 is dorsal column of high cervical cord, N19 is in thalamus and P23 is thalamocortical radiation or parietal sensory cortex.

진행성 치매와 반복되는 뇌졸중을 보인 뇌 아밀로이드 혈관병증 1예

유봉구,곽강호,김태유,김광수,유경무 대한치매학회 2004 Dementia and Neurocognitive Disorders Vol.3 No.1

Cerebral amyloid angiopathy can cause intracerebral hemorrhage, progressive dementia, seizure and transient ischemic attacks. Dementia is a relatively common manifestation and associated with the presence of recurrent strokes and leukoencephalopathy. A 66-year-old right-handed man with hypertension and recurrent strokes presented with rapidly progressive dementia and sudden onset of dysarthria and dizziness. He showed memory impairment, personality and behavioral changes, and executive dysfunction for one and an half years. These symptoms developed insidiously and quite rapidly without fluctuation. Brain CT showed a small hemorrhage in the right cerebellum. Brain MRI, especially gradient-echo images revealed multiple cortical and cortico-subcortical microbleeds. Four weeks later, right hemiparesis suddenly developed and a repeated MRI showed a new left corona radiata infarction. We learn from this case that gradient-echo MR images should be performed in patients with rapidly progressive dementia and recurrent strokes.