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복강경하 근치적 신절제술 후에 발생한 급성 신부전을 동반한 횡문근 융해증
옥주현 ( Ju Hyun Oak ),정미향 ( Mi Hyang Jung ),황병희 ( Byung Hee Hwang ),유선홍 ( Sun Hong Yoo ),박기훈 ( Ki Hoon Park ),김지훈 ( Ji Hun Kim ),안서희 ( Seo Hee Ann ),김용균 ( Yong Kyun Kim ),송호철 ( Ho Cheol Song ),최의진 ( Eui 대한신장학회 2009 Kidney Research and Clinical Practice Vol.28 No.1
Postoperative rhabdomyolysis with acute renal failure (ARF) is a rare complication of laparoscopic urologic surgery. It is associated with lateral decubitus surgical position, long operative time, and increased body mass. We report a case of a 49-year-old-man with right renal cell carcinoma who underwent a laparoscopic right radical nephrectomy for 7 hours in left decubitus position and was complicated by ARF due to postoperative rhabdomyolysis. Laparoscopic renal surgery is performed in many surgical renal diseases and heightened suspicion may help early recognition of postoperative rhabdomyolysis. Vigorous hydration and hemodialysis are also helpful in treating ARF secondary to rhabdomyolysis.
헬리코박터 관련 소화성궤양 환자에서 위산펌프길항제 사용이 요소호기검사 결과에 미치는 영향
옥주현 ( Ju Hyun Oak ),정우철 ( Woo Chul Chung ),정성훈 ( Sung Hoon Jung ),최강현 ( Kang Hyun Choi ),김은정 ( Eun Jung Kim ),강봉구 ( Bong Koo Kang ),강보라미 ( Bo Ra Mi Kang ),공시은 ( Si Eun Kong ),백창렬 ( Chang Nyol Paik ),이 대한소화기학회 2011 대한소화기학회지 Vol.57 No.1
Background/Aims: Revaprazan (Revanex(R)) is a novel proton pump inhibitor (PPI) that has a somewhat different effect on proton pump compared with the other PPI`s, also (called as `acid pump antagonist`). We aimed to examine the false negative rate of (13)C-urea breath test (UBT) in the patients with Helicobacter pylori (H. pylori) associated peptic ulcer disease who were treated with revaprazan and evaluate the anti-urease activity of revaprazan. Methods: Total 55 patients were enrolled in this study. They received EGD examination between January 2009 and December 2009 and diagnosed histologically as H. pylori associated peptic ulcer disease. All patients took revaprazan only. Three patients were excluded because of underlying chronic disease and inappropriate breath sampling. The remaining 52 patients had UBT at 0, 2 and 4 weeks of revaprazan use. After 2 weeks of the cessation of revaprazan, they had the fourth UBT. Results: At 2 and 4 weeks, the false negative rates of UBT were 5.8% and 23.1%, respectively (p=0.05). After 2 weeks of the cessation, the cases of the false negative result were five. Four out of five patients had prolonged negative results on two or three successive tests, and baseline (13)C difference value did not predict the false negative results. Conclusions: False negative results of UBT were common and increased with prolonged use of acid pump antagonist. As PPI, it had also anti-urease activity and most patients (47/52, 90.4%) reverted to positive results by 2 weeks after the cessation of taking the medication. (Korean J Gastroenterol 2011;57:8-13)
옥주현 ( Ju Hyun Oak ),정우철 ( Woo Chul Chung ),정지한 ( Ji Han Jung ),김진동 ( Jin Dong Kim ),이정록 ( Jeong Rok Lee ),백창렬 ( Chang Nyol Paik ),이강문 ( Kang Moon Lee ),조규도 ( Kyu Do Cho ) 대한소화기학회 2008 대한소화기학회지 Vol.52 No.1
Carcinosarcoma of the esophagus is a rare malignancy accounting for approximately 1-2% of all esophageal neoplasms. It presents as a bulky intraluminal polypoid lesion mainly in the mid to lower esophagus, which harbors both carcinomatous and sarcomatous components histologically. It often presents relatively early because of its rapid intraluminal growth. We report the case of a 69-year-old man who had suffered from dysphagia for 1 month. He was previously admitted to the hospital due to corrosive esophagitis caused by ingestion of acetic acid. Endoscopy and radiological studies revealed a bulky polypoid mass with superficial ulcerations and mucosal friability, measuring 10 cm in length approximately, in the mid-esophagus. Subtotal esophagectomy with esophagogastrostomy was done. Microscopically it was composed of sarcomatous component intermingled with squamous cell carcinoma. Immunohistochemical stains reveal cytokeratin, 34βE12, and p63 positivity in the nests of carcinoma, and desmin and vimentin positivity in the spindle cells of sarcomatous stoma. (Korean J Gastroenterol 2008;52:42-47)
이달의 X-선 : 패렴을 동반한 기관 및 주기관지의 확장 소견
주겨레 ( Kyu Re Joo ),옥주현 ( Ju Hyun Oak ),이성은 ( Sung Eun Lee ),장석태 ( Suk Tae Jang ),김성경 ( Sung Kyoung Kim ),이상학 ( Sang Haak Lee ),송정섭 ( Jeong Sup Song ),박성학 ( Sung Hak Park ),문화식 ( Hwa Sik Moon ),이배영 ( B 대한결핵 및 호흡기학회 2006 Tuberculosis and Respiratory Diseases Vol.61 No.4
저자들은 폐렴을 동반한 기도의 드문 질환인 Mounier-Kuhn syndrome을 가진 환자의 단순흉부방사선, 기도내시경 소견과 함께 고식적인 흉부 전산화 단층 촬영을 시행 후 3차원적인 입체 영상으로 재구성한 소견을 고찰과 함께 1예 보고하는 바이다. A 66-years-old man was refered to our hospital because of cough, sputum, chill and fever. Enlargement of the trachea and main bronchi on radiography and bronchoscopy is compatible with Mounier-Kuhn syndrome. Mounier-Kuhn syndrome or tracheobronchomegaly is a rare disorder of uncertain etiology, characterized by marked dilatation of the trachea and major bronchi. This syndrome is associated with tracheal diverticulosis, bronchiectasis and recurrent respiratory tract infection. We report a rare case of Mounier-Kuhn syndrome with pneumonia and literature reviews. (Tuberc Respir Dis 2006; 61: 403-406)
신장 ; 신장이식 환자에서 발생한 시롤리무스에 의한 폐렴
김진석 ( Jin Seok Kim ),신아영 ( Ah Young Shin ),김정호 ( Jeong Ho Kim ),김은혜 ( Eun Hye Kim ),옥주현 ( Ju Hyun Oak ),양철우 ( Chul Woo Yang ) 대한내과학회 2010 대한내과학회지 Vol.79 No.4
Sirolimus에 의한 폐렴은 드믈지만 사망사례가 보고될 정도로 심각한 질환으로, 빠른 진단과 sirolimus의 사용 중단으로 대부분 후유증없이 치료될 수 있다는 점에서 주의가 요구되는 합병증이라 할 수 있다. 저자들은 신이식 후 sirolimus를 3개월간 사용하던 51세 남자 환자에서 sirolimus에 의한 폐렴을 경험하였기에 문헌고찰과 함께 보고하는 바이다. Sirolimus is a promising immunosuppressive agent with low nephrotoxicity and anti-tumor effects; it replaces calcineurin inhibitors, but serious adverse effects have been reported. We report on sirolimus-induced pneumonitis, which is a rare but fatal complication. The patient was a 51-year-old renal transplant recipient who had received sirolimus for 3 months before admission. The patient had a productive cough and mild fever, which began 3 weeks before admission. The chest PA and CT findings were consistent with pneumonia, but a microbiological study and bronchoscopic findings revealed no evidence of infection. Sirolimus-induced pneumonitis was suspected, so the sirolimus was stopped and high-dose steroids were initiated. The respiratory symptoms and radiologic findings improved dramatically after sirolimus withdrawal and the initiation of steroid treatment. These findings strongly suggest a casual relationship between sirolimus and pneumonitis. This is the first case of sirolimus-induced pneumonitis in Korea. (Korean J Med 79:438-442, 2010)