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        뇌의 확산강조 영상에서 b-value의 변화에 따른 신호강도, 현성확산계수에 관한 비교 분석

        오종갑(Jong-Kap Oh),임중열(Jung-Yeol Im) 대한방사선과학회(구 대한방사선기술학회) 2009 방사선기술과학 Vol.32 No.3

        Diffusion-weighted imaging (DWI) has been demonstrated to be a practical method for the diagnosis of various brain diseases such as acute infarction, brain tumor, and white matter disease. In this study, we used two techniques to examine the average signal intensity (SI) and apparent diffusion coefficient (ADC) of the brains of patients who ranged in age from 10 to 60 years. Our results indicated that the average SI was the highest in amygdala (as derived from DWI), whereas that in the cerebrospinal fluid was the lowest. The average ADC was the highest in the cerebrospinal fluid, whereas the lowest measurement was derived from the pons. The average SI and ADC were higher in T₂-DW-EPI than in FLAIR-DW-EPI. The higher the b-value, the smaller the average difference in both imaging techniques; the lower the b-value, the greater the average difference. Also, comparative analysis of the brains of patients who had experienced cerebral infarction showed no distinct lesion in the general MR image over tims. However, there was a high SI in apparent weighted images. Analysis of other brain diseases (e.g., bleeding, acute, subacute, chronic infarction) indicated SI variance in accordance with characteristics of the two techniques. The higher the SI, the lower the ADC. Taken together, the value of SI and ADC in accordance with frequently occurring areas and various brain disease varies based on the b-value and imaging technique. Because they provide additional useful information in the diagnosis and treatment of patients with various brain diseases through signal recognition, the proper imaging technique and b-value are important for the detection and interpretation of subacute stroke and other brain diseases. 확산강종영상 (diffusion weighted image, DWI)은 급성 뇌경색, 뇌종양, 뇌백질 질환, 뇌 막질의 확산 정도 등 여러 뇌질환의 진단을 획기적으로 향상시켰으며 그 활용도가 증가하고 있다. 본 연구는 10~60대 환자들의 뇌를 대상으로 두 기법간의 신호강도, 현성확산계수의 평균치를 측정하였다. 그 결과, 확산강조영상에서는 신호강도 평균값은 편도체부 (amygdala)가 가장 높고, 뇌척수액(cerebrospinal fluid)에서 가장 낮았다 현성확산계수의 평균값은 뇌척수액이 높고, 교뇌 (pons)가 낮게 측정되었다. 확산강조 신호강도와 현성확산계수의 평균값은 T₂-DW-EPI 기법보다 높고, b-value의 변화에 따른 평균값은 두 기법의 b-value에 모두 반비례하였다. 또한 뇌경색환자의 뇌의 시간 경과에 따른 분석결과, 초급성뇌경색 환자의 일반적인 MR 영상에서는 병변부분이 명확하지 않았으나 확산강조영상에서는 고신호강도로 나타났다. 출혈성 뇌경색, 급성 뇌경색 등 여러 질환별로 분석한 결과 그 두 기법의 특성에 따라 신호강도의 값이 차이가 클수록 현성확산계수는 낮게 나타났다. 결론적으로 뇌 질환이 자주 발생되는 부위와 뇌 질환의 환산강조 신호강도 및 현성확산계수 값은 b-value의 변환과 영상기법에 따라 각각 다르게 나타났다. 이러한 정략적인 결과를 바탕으로 보다 안정적인 기법과 적절한 b-value 값을 이용하여 검사를 한다면 여러 뇌의 질환 및 병변 등을 발견, 판독하는 것뿐만 아니라 정상부위나 질환에 따른 기법별 신호의 인지를 통한 정확한 질병 진단과 치료에 중요한 의미가 있다고 사료된다.

      • 4D Volume Rendering 기법을 이용한 Brain MR Angiography Circle of Willis artery의 형태학적 분석

        오종갑(Jong Kap Oh) The Research and Information Service 2001 남부대학교 논문집 Vol.1 No.-

        The technique that is called MR Angiography has been greatly developed by the advancement of the MRI device and the checkup methods. The rapid development of the computer has made it easier, better, faster, and more accurate to get three-dimentional images in the gaining methods of medical images. Since the appearance of MDCT(Multi-Detector Computed Tomography), 4D Volume Rendering technique is used to reconstruct and post process volume scanned data. With the help of 3D and 4D images gained with the technique and located as the necessity to clinical and medical image diagnosis, it is possible to give a fine look at the anatomical structure . Thus, this approach, using Advantage Workstation 4D Volume Rendering technique mainly used in MDCT volume data post processing, tried to analyze the data gained by Brain MR Angiography checkup(3D-TOF SPGR). The subjects are the 231 patients who had visited Chomdan hospital from Nov. 15, 2005 to Feb. 27, 2006 and taken a Brain MR Angiography examination. As the Materials methods, the Standard Head coil of 1.5 tesla superconductive magnetic resonance imaging camera(Signa 9H/i, GE medical system) using the checkup technique using the phenomena that emphasize the blood flow singals(3D Time-of-Flight: 3D-TOF SPGR) is used to examine . The scope of examination when gaining images is from Petrosal segment to Anterior cerebral artery 4-portion. The parameter are these: TR=27msec, TE=3.6/fr.msec, Thickness=0.8mm, Field of view =22~24cm, NEX=1 , Matrix=512*192, SL=208, TR=10,000 msec, TE=134,9msec, IR=2500, Rx scanning time=5min52sec. The case that the circle of Willis artery is normally shown, the shape of Anterior cerebral artery A1 portion, the length, diameter, and shape of Anterior communicating artery(A-com a), the length and diameter of Basilar artery, the metamorphosis of Posterior cerebral artery, and the shape of Vertebral artery are analyzed. The package of statistical results of gained data is processed statistically using MINI TAP 14. The age of the subjects is between 4 and 80. The average age of man is 45.5±14.6 and the number of them is 98(42%). The average age of woman is 52.3±14.6, and the number of them is 133(58%). The average age of all is 49±15.2. Morphologically, the case that Circle of willis artery is normally shown is 33(14.3%), and woman(23, 17. 3%) is more in number than man(10, 10.2%). The case that Circle of willis artery is abnormally shown(A number of A-com a, P-com a) is 31(13.4%), and woman is 27(10.3%). The case that either A-com a or P-com a is shown dimly is 24(10.3%), and the case that either A-com a or P-com a is not shown is 59(25.5%), and the case that both of them are not shown is 76(32.9%). Woman is 3.9% higher in average. The A1 potion that either of them is made thin is 20(8.6%), and the A1 potion that both of them are not shown is 12(5.1%). The Vertebrate artery case that either of them is made thin is 34(14.7%) and the Vertebrate artery case that both of them are not shown is 7(3%). The results of the length and diameter of Circle of Willis Communicating artery and Basilar artery are those : Average Length of Rt, P-com a = 11.7±4.7 mm, Length of Lt, P-com a = 12.8± 5.6mm, Diameter of Rt, P-com a = 1.1±1.6mm, Diameter of Lt, P-com a = 0.9±1.3mm, Average Length of A-com a = 3.2±6.0mm, Length of Man's A-com a = 3.6±6.9mm, Length of Woman's A-com a = 2.8±5.2mm, Average Length of Basilar artery = 27.9± 5.2mm, Average Diameter of Basilar artery = 3.1± 3.4mm. The results of this research are gained by applying 4D Volume Rendering technique into MR Angiography Volume scanned data post processing. The reconstructed data from MR Angiography 4D Volume Rendering gained various artery and Basilar artery are those: Average Length of Rt, P- com a = 11.7±4.7 mm, Length of Lt, P-com a = 12.8± 5.6mm, Diameter of Rt, P-com a = 1.1±1.6 mm, Diameter of Lt, P-com a = 0.9± 1.3mm, Average Length of A-com a = 3.2±6.0mm, Length of Man's A-com a

      • KCI등재
      • KCI등재
      • KCI등재후보

        MDCT 관상동맥 조영 검사에서 전향적 동조화 및 후향적 동조화 기법의 화질과 선량 관계

        오종갑(Jong-Kap Oh) 대한방사선과학회(구 대한방사선기술학회) 2011 방사선기술과학 Vol.34 No.4

        The goal of this study is to reduce patient exposure dose by providing image quality and radiation dose according to inspection methods. Volume Computed Tomography Dose Index(CTDIvol) and Dose Length Product(DLP) of prospective and retrospective ECG gating snapshot segment of Coronary CT angiography(CTA) were measured each snapshot segment methods. CT number, noise, uniformity, and resolution were also measured using phantom under the same condition of coronary CTA. The results showed that CT number, noise, uniformity and resolution are similar to each other. In terms of CTDIvol and DLP, however, measurement dose of prospective ECG gating snapshot segment was lower than the retrospective case by 37.5% and 40.3%. Therefore, it is highly recommended that in the coronary CTA, prospective ECG gating scan mode should be chosen to reduce patient dose. 본 연구는 검사 기법에 따른 영상의 질과 방사선 피폭의 정도를 제시하여 검사자가 받는 방사선 피폭을 저감시키는 데 목적이 있다. 관상동맥 전산화 단층 혈관조영(Coronary CTA, coronary computed tomography angiography) 검사자를 대상으로 SnapShot Pulse의 전향적 동조화 기법과 SnapShot Segment의 후향적 동조화 기법으로 coronary CTA 검사에서 검사자가 받는 단면 피폭선량(CTDIvol, volume computed tomography dose index), 총 피폭선량(dose-length product; DLP)을 각각 측정하였다. 또한, Coronary CTA 촬영조건을 동일하게 팬텀을 이용하여 CT감약계수, 노이즈 및 균일도, 공간분해능을 측정하였다. 연구 결과 두기법에서 CT감약계수, 노이즈 및 균일도, 공간분해능의 질적 수준이 비슷하게 나타났으며, CTDIvol, DLP는 SnapShot Segment의 후향적 동조화 기법에 비해 피폭선량이 약 37.5%, 40.3% 감소되었다. 임상에서 coronary CTA 검사 시 SnapShot Pulse의 전향적 동조화 기법을 적극 채택하여 검사자가 받는 방사선 피폭을 감소시키기 위한 노력이 절실히 요구된다.

      • KCI등재

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