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국소성 융모막암종 분화를 동반한 S상결장의 원발성 선암종
오숙경 ( Sook Kyoung Oh ),김형욱 ( Hyung Wook Kim ),강대환 ( Dae Hwan Kang ),최철웅 ( Cheol Woong Choi ),최유이 ( Yu Yi Choi ),임홍규 ( Hong Kyu Lim ),구자준 ( Ja Jun Goo ),최성열 ( Sung Yeol Choi ) 대한소화기학회 2015 대한소화기학회지 Vol.66 No.5
Primary colorectal choriocarcinoma is a rare neoplasm. Only 19 cases have been reported worldwide, most of which involved adenocarcinomas. The prognosis is usually poor, and the standard therapy for this tumor has not been established. A 61-year-old woman presented with constipation and lower abdominal discomfort. She was diagnosed with primary adenocarcinoma with focal choriocarcinomatous differentiation in the sigmoid colon and liver metastasis. Because the serum beta-human chorionic gonadotropin level was not significantly elevated, and because only focal choriocarcinomatous differentiation was diagnosed, we selected the chemotherapy regimen that is used for the treatment of metastatic colorectal adenocarcinoma. The patient survived for 13 months after the initial diagnosis. This is the first case in Korea to assess the suppressive effects of the standard chemotherapy for colorectal adenocarcinoma against coexisting colorectal choriocarcinoma and adenocarcinoma. (Korean J Gastroenterol 2015;66:291-296)
간호 대학생의 건강정보추구행동이 건강증진행위실천에 미치는 영향
문인오(Moon, Inn Oh),박숙경(Park, Sook Kyoung),김은경(Kim, Eun-Gyeong) 한국보건간호학회 2015 韓國保健看護學會誌 Vol.29 No.2
Purpose: The purpose of this study was to analyze factors affecting health promotion behavior among nursing students according to health information seeking behavior. Methods: The study design was a descriptive survey and questionnaires were collected from 240 nursing students who have studied in nursing colleges located in “J” province. Data were analyzed using frequency, percentage, mean, standard deviation, independent t-test, One-way ANOVA, Scheff? test, Pearson Correlation, and hierarchical multiple regression. Results: In Model Ⅰ, general characteristics influenced of 17.6% of health promotion behavior factors. Health status, selection criteria and frequency of information search were statistically useful as influencing of health promotion behavior factors. In addition, in model Ⅱ health information seeking behavior influenced of 18.1% of health promotion behavior factors. Conclusion: The results indicate that the health information seeking behaviors proved the influence on health promotion behavior of nursing students
Anti-TNF-α 치료를 받은 강직성 척추염 환자들의 체중과 골밀도 변화
이장원 ( Jang Won Lee ),정민석 ( Min Suk Jung ),김동현 ( Dong Hyun Kim ),이승현 ( Seung Hyun Lee ),오숙경 ( Sook Kyung Oh ),조영선 ( Young Sun Jo ),변상환 ( Sang Hwan Byun ),남경민 ( Kyoung Min Nam ),이충원 ( Choong Won Lee ) 대한내과학회 2013 대한내과학회지 Vol.85 No.5
Background/Aims: To determine the changes in body weight and bone mineral density in patients with ankylosing spondylitis (AS) receiving anti-tumor necrosis factor-α (TNF-α) treatment. Methods: Thirty-one patients with AS (25 males and 6 females) who fulfilled the Modified New York Criteria for AS were included in this retrospective study. All patients had active disease that eventually required anti-TNF-α treatment. Each patient received anti-TNF-α treatment (etanercept 25 mg twice weekly or adalimumab 40 mg twice monthly) for more than 2 years. Body weight, disease activity as Bath ankylosing spondylitis disease activity index (BASDAI), C-reactive protein, erythrocyte sedimentation rate (ESR), lumbar bone mineral density (LBMD), and femoral bone mineral density (FBMD) were measured at baseline and at 1 and 2 years after initiating anti-TNF-α treatment. Results: There was a significant increase in mean body weight at 1 year (1.1 ± 3.8 kg) and at 2 years (1.7 ± 4.8 kg) compared with baseline. The gains in mean BMD of the lumbar spine were significant at 1 year (0.4 ± 0.4) and 2 years (0.5 ± 0.7) compared with baseline. Mean BMD of the femur was also increased at 1 year (0.08 ± 0.7) and 2 years (0.1 ± 0.8) compared with baseline, but these differences were not statistically significant. There were significant decreases in BASDAI at 1 year (-3.3 ± 2.8) and at 2 years (-3.6 ± 2.8) compared with baseline. Conclusions: This study showed significant increases in body weight, lumbar BMD, and BASDAI at 1 year and 2 years in patients with ankylosing spondylitis after receiving anti-TNF-α treatment. (Korean J Med 2013;85:489-494)
소화기 ; 검진 내시경 상 구불 결장의 상피하 병변으로 관찰된 충수염 1예
최유이 ( Yu Yi Choi ),김수진 ( Su Jin Kim ),강대환 ( Dae Hwan Kang ),김형욱 ( Hyung Wook Kim ),최철웅 ( Cheol Woong Choi ),오숙경 ( Sook Kyoung Oh ),신영신 ( Young Shin Shin ) 대한내과학회 2015 대한내과학회지 Vol.89 No.5
본 증례는 검진 목적의 대장내시경에서 충수돌기 개구부가 정상 소견을 보였지만, 구불결장의 점막하 병변으로 나타난 충수염의 드문 증례이다. 화농성 배액이 보이는 점막하 병변이 구불 결장에서 관찰될 때 충수염의 가능성 또한 감별진단으로 고려해 볼 수 있겠다. Acute appendicitis is common in all age groups. Although many patients with acuteappendicitis present with migrating abdominal pain, the initial presentation can be atypical and nonspecific. Unusual manifestations can lead to diagnostic delay, which is associated with increased morbidity and mortality. Colonoscopic findings suggestinga diagnosis of asymptomatic appendicitis include hyperemia and bulging at the appendiceal orifice area with surrounding mucosal edema, and drainage of pus from the appendiceal orifice. We report a case of asymptomatic perforated appendicitis and periappendiceal abscess that presented as a subepithelial sigmoid colon lesion at screening colonoscopy. On colonoscopy, a subepithelial lesion with pustular drainage surrounded by hyperemic mucosa was seen at the sigmoid colon. Computed tomography revealed appendicitis and a periappendiceal abscess with adjacent sigmoid colon wall thickening. The patient underwent an appendectomy, with a final diagnosis of a perforated appendicitis with a periappendiceal abscess. (Korean J Med 2015,89:548-552)