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하수오가미방이 고지혈증 SHR 및 항산화에 미치는 영향
김수익,김남욱,전상윤,홍석,Kim, Su-Ik,Kim, Nam-Uk,Jean, Sang-Yun,Hong, Seok 대한한방내과학회 2009 大韓韓方內科學會誌 Vol.30 No.4
Objectives : This study was designed to evaluate the effect of Hasuogamibang (HGB) on hyperlipidemia and antioxidant activity. Methods : For this study, we divided four groups of rats (normal WKY group, normal SHR group, high cholesterol diet and saline-treated SHR group, high cholesterol diet and HGB-treated SHR group), and observed the change of body weight, weight of liver, cholesterol, triglyceride, glucose, albumin, histologic change of liver and aorta, lipid peroxidation and antioxidant activity of liver tissue, and cholesterol gene revelation control efficiency. Results : Total-cholesterol, LDL-cholesterol, triglycerides were decreased significantly by HGB. However, HDL-cholesterol increased significantly. The tissue of liver and aorta were controlled defect by HGB on histologic study. Lipid peroxidation and SOD of liver tissue was decreased significantly by HGB. Gene revelation of ACAT and HMG CoA reductase in hepatic tissue was decreased significantly by HGB. Conclusion : This study suggests that HOB is significantly effective on hyperlipidemia and antioxidant activity.
효소면역측정법에 의한 국내산 된장과 고추장 중 Aflatoxin B1의 오염도 조사
배수익,곽보연,박윤경,김영호,손동화,Bae, Soo-Ick,Kwak, Bo-Yeon,Park, Yun-Kyung,Kim, Young-Ho,Shon, Dong-Hwa 한국식품위생안전성학회 2003 한국식품위생안전성학회지 Vol.18 No.3
된장과 고추장에 대해 cdELISA에 의한 $AFB_1$의 분석방법을 확립하고 국내에서 생산되는 재래식 및 개량식 된장과 고추자을 수거하여 $AFB_1$의 오염도를 조사하였다. 표준곡선을 작성하였을 때, 이의 검출 한계는 0.2 ng/m(ppb)이었다. 된장의 Spike test 후 회수율은 1~100 ng/g 범위에서 평균 71.5%로 나타나 이 범위에서 cdELISA에 의한 $AFB_1$의 측정이 가능함을 보여주었다. 이로부터 된장 및 고추장에서 cdELISA를 통한 $AFB_1$의 분석 방법을 확립하였다. 된장 및 고추장 시료의 $AFB_1$의 오염도는 총 30종의 고추장 시료에서는 $AFB_1$이 검출되지 않았고 총 30종의 된장 시료 중 6종에서 1.0~6.0 ng/g 수준으로 검출되었다. 이는 우리 나라의 허용 기준인 10 ng/g(ppb) 이하였다. Competitive direct enzyme-linked immunosorbent assay(cdELISA) of aflatoxin $B_1$ ($AFB_1$) in deonjang(Korean-style soybean paste) and kochujang(fermented hot peppersoybean paste) and the level of $AFB_1$ in modern or traditional style deonjang and gochujang, produced in Korea, was surveyed by cdELISA. From the standard curve of the cdELISA, the detection limit of $AFB_1$ was 0.2 ng/m/. The average recovery of $AFB_1$ was 71.5% in the range of 1~100 ng/g after spiking $AFB_1$ into deonjang and it means that it could be possible to detect the $AFB_1$ in these range by the cdELISA in deonjang. Among the 30 kochujangs tested, no $AFB_1$ was detected in kochujangs. Among the 30 deonjangs, $AFB_1$ was detected in 6 ones in the range of 1.0~6.0 ng/g. The occurrence of $AFB_1$ in deonjang and kochujang tested in this study was less than the Korea Standard and Specification of aflatoxin in foods (10 ppb).
장수익(Jang Soo Ik),강인준(Kang In Joon),강호윤(Kang Ho Yun) 대한공간정보학회 2010 대한공간정보학회지 Vol.18 No.4
최근 집중호우로 인한 절토사면의 붕괴사고가 매년 반복적으로 일어나고 있는 실정이다. 절토사면의 붕괴로 인하여 인명피해와 도로유실 등 많은 재해를 일으키고 있어 절토사면의 유지관리가 필요하다. 절토사면의 유지관리를 위한 현황조사 양식중에서 일반현황을 살펴보면 피해지역의 위치를 도로상의 거리표와 경위도로 나타내고 있기 때문에 피해지역의 위치와 사면의 형상파악이 어렵다. 따라서 본 논문에서는 피해지역의 정확한 위치와 사면의 형상을 표시하기 위해 NTRIP서비스를 이용한 해양 DGPS기준국에서 수신하는 GPS 보정신호를 통한 NDGPS방법과 VRS 서비스를 이용한 방법에 대해 분석하였다. 분석한 결과, 두 방법 모두 실제 절토사면과 비슷한 형상의 사면이 나타나 차후 다른 연구지역의 절토사면조사에도 적용이 가능할 것으로 판단된다. With recent localized heavy rain, the collapsing accident of the cut slopes occur repeatedly every year. The maintenance of the cut slopes is very crucial as the collapsing of cut slopes causes various calamities such as human causalities and sweeping away of the roads. By looking at the study of current situation of the cut slopes, designed for maintenance of cut slopes, the locations of the damaged districts are hard to figure out as they are represented through distance mark and longitude and latitude. In this paper has used NDGPS methods and VRS service through GPS signal corrections that are received by DGPS standard department to correctly analyze the exact location and the shape of the slope. The result of this analysis shows that both methods produce similar shape of the slope. Therefore, these two methods, NDGPS methods and VRS service, can be applied to other analysis of cut slopes in different areas.
플라스틱 마이크로칩 제작을 위한 솔벤트 본딩에 관한 연구
민정기(Junggi Min),윤호영(Hoyoung Yun),오수익(Soo Ik Oh),한동철(Dong-Chul Han) 대한기계학회 2009 대한기계학회 춘추학술대회 Vol.2009 No.5
Glass, silicon, and ceramic substrates have been mainly used in lab-on-a-chip fields and micro fluidics. Recently, plastic substrates have been employed increasingly because fabrication costs are inexpensive, manufacturing process is simple, and mass production is possible. In particular, PMMA, PC, and COC substrates which are similar to optical properties of the glass substrates have been implemented. Main issues of using plastic substrates are to bond two substrates without damage of the microchannel. In this paper, microchips have been fabricated with solvent bonding among the various bonding methods which are proper to mass production. And we present solvent bonding method does not penetrate into the microchannel.