사회적 기술 훈련 집단프로그램이 다문화가정 아동의 사회적 기술 향상 및 부정적 자동적 사고와 스트레스 수준의 감소에 미치는 효과

염승희,신현균,오수성 한국임상심리학회 2010 Korean Journal of Clinical Psychology Vol.29 No.3

This study examined the effects of a social skills group-training program, based on the cognitive-behavioral approach, on the social skills, negative automatic thoughts, and stress levels of international couples' children. The participants were 17 3rd to 6th-grade elementary-school students whose mothers were international marriage immigrants. Nine children participated in an experimental social skills training program, and 8 children participated in a learning skills training program, as the control group. Each program comprised 10 sessions. We used a social skills rating system, the Korean-children's Automatic Thought Scale, and a stress scale for the participants' pre-and post-tests. The results showed a statistically significant reduction solely in the experimental group's general stress and negative automatic thoughts, and a marginally significant improvement in only that group's social skills after the program. We had a limited ability to rigorously test the program's effects because of small sample size and problems with the representativeness of the sample and random assignment of the groups. In spite of these limitations, our results suggest that this social skill training for international couples' children, who are a high-risk group in our society, may have a preventive effect through positive change related to psychosocial adjustment.

여러 가지 삼환계 항우울제가 쥐의 하복신경 전기자극 후 정관수축에 미치는 효과의 비교

염승희,서경근,김세철 大韓泌尿器科學會 2001 Korean Journal of Urology Vol.42 No.7

중금속 유도 산화적 스트레스에 대한 금은화의 세포 보호 효과

염승희,박선빈,박선동,박광일,김영우 대한한의학방제학회 2022 大韓韓醫學方劑學會誌 Vol.30 No.3

Objectives : Lonicera japonica is known for anti-inflammation and antibiotic effect in Korean medicine. This study aimed for investigating the cytoprotective effect of Lonicera japonica extract (LJE) for HepG2 cells against arachidonic acid (AA)+iron-induced oxidative stress. Methods : The effect of LJE on cell viability was assessed by MTT assay. ROS assay was selected to assess antioxidant effect of LJE. To assess LJE’s effect on mitochondrial function, flow cytometric analysis was operated. And immunoblot analysis was used to establish the underlying mechanism of LJE. Results : LJE protected HepG2 cells against AA+iron-induced oxidative stress by phosphorylation of liver kinase B1 and blocked the decline of procaspase 3. Also, LJE preserved the mitochondrial membrane permeability induced by AA+iron. Conclusion : LJE protected the hepatocyte from AA+iron-induced oxidative stress by activation of LKB1 by the preservation of mitochondrial functions.

야뇨증 환아에서 치료 전후의 자아의 변화

장인호,염승희,김경도,이영식 大韓泌尿器科學會 2001 Korean Journal of Urology Vol.42 No.10

남성 요로생식 기관에서 Human Beta-Defensin의 발현

장인호,염승희,명순철,김영선 대한감염학회 2001 감염 Vol.33 No.4

Background : Defensins are small (3.5∼5 kDa) cationic antimicrobial peptides that have a broad spectrum of activity that includes gram-negative bacterias, yeasts and enveloped viruses. The defensins contain six cysteine residues forming three disulfide bridges depending on the spacing of the cysteine residues and the connectivity of the disulfide bridge, defensins are classified into two families, the α -defensins (HNP) and, β-defensins (HBD). Recently two human epithelial beta defensins, HBD-1 and HBD-2 have been identified. HBD-1 has been detected in a number of normal mucosal sites, but HBD-2 is highly restricted in its expression by inflammatory stimulations, we invesigated the expression of hunam beta defensin in human male urogenital organs. Methods : Specimens of normal human male testis, epididymis, prostate, seminal vesicles, vas deferens, urethra, bladder, ureter, kidney, pyelonephritis, epididymitis, clear renal cell carcinoma and transitional cell carcinoma of bladder were obtained as discarded material from urological surgery. Each sample was stored at snap frozen in liquid nitrogen subsequent to RNA extraction. Reverse transcription polymerase chain reaction (RT-PCR) was used to semiquantitate HBD-1 and HBD-2 mRNA using the housekeeping gene beta-actin as an internal control. Southern blotting and sequencing showed HBD-1, 2 expressions in male urogenital organs. Results : We checked the expression of HBD-1, 2 mRNA in all specimen of normal human male urogenital organ, pyelonephritis, epididymitis, clear renal cell carcinoma and transitional cell carcinoma of bladder by RT-PCR and southern blotting analysis. We checked the homolgy of HBD-1, 2 by bands sequencing. Conclusion : Our study indicated that the normal male urogenital organs, infection and neoplasm in male urogenital organs expresses antimicrobial peptides. These may play an important role in the prevention of infections by bacterias, antimicrobial effects in infection and anticancer effects in neoplasm of male urogenital organs. These natural endogenous antibiotic peptides could be developed as novel therapeutic agents for fighting infections and neoplasms of the human male urogenital organs. (Korean J Infect Dis 33:233∼241, 2001)

黃芩湯 표준화 및 KCD 질병코드 연구 – 동의보감 및 PUBMED를 중심으로

박선빈,염승희,김수진,한유정,이지호,김영우,박선동 대한한의학방제학회 2022 大韓韓醫學方劑學會誌 Vol.30 No.1

Objectives : Huangqintang(黃芩湯) is a famous herbal prescription in the Traditional Korean Medicine (e.g. Shanghanlun) to treat various chronic disease such as neurological disease and digestive system disease. Its components include Scutellariae Radix(黃芩), Paeonia lactiflora(芍藥), Glycyrrhizae Radix et Rhizoma(甘草), Zizyphi Fructus(大棗). Methods : In this study, we standardize the name, composition and medical uses of Huangqintang by literature studying and paper searching. Based on the comparison between oriental medicine and modern medicine pharmacology, we linked the medical uses of Huangqintang to Korean Standard Classification of Diseases (KCD). Results and Conclusion : The name of the prescription is unified into “Huangqintang”, and its composition ratio between Scutellariae Radix, Paeonia lactiflora, Glycyrrhizae Radix et Rhizoma, and Zizyphi Fructus is 3:2:2:3. Huangqintang is used for enteritis diseases due to its antipyretic and antinflammatory effects. Its medical application was relatied with 'A'code, 'C'code, and 'K'code as indicated by KCD. By standardizing the mixed conceptions of Huangqintang, this review will facilitate the coding of Huangqintang prescription. Therefore, it will make Huangqintang prescription more useful in clinics.

여성 복압성요실금 환자에서 tension-free vaginal tape (TVT)와 transobturator vaginal tape inside-out (TVT-O) 수술법의 1년 추적 결과 비교: 전향적 연구

최양수,주명수,박서용,염승희,김진범,송승훈,두진경,이규성 대한배뇨장애요실금학회 2005 International Neurourology Journal Vol.9 No.2

Purpose: To compare prospectively and randomly tension-free vaginal tape (TVT) with transobturator vaginal tape inside-out (TVT-O) for the surgical treatment of female stress urinary incontinence (SUI). Materials and Methods: One hundred twenty women with SUI were alternately assigned to either the TVT group (n=60) or TVT-O group (n=60). The preoperative evaluation included urodynamic study and a Korean version of the incontinence quality of life questionnaire (I-QoL). At 1-year after operation, surgical outcome, patient I-QoL parameters, long-term complications and uroflowmetry were evaluated in 2 groups. Results: Preoperative patient characteristics including I-QoL and urodynamic study were comparable in the two groups. The rates of cure (86.8% for TVT vs. 86.8% for TVT-O), improvement (6.6% for TVT vs. 8.2% for TVT-O), and failure (6.6% for TVT vs. 5.0% for TVT-O) were similar for the two groups. The I-QoL parameters one year after surgery were improved significantly in both groups (p<0.001) and there was no difference between the two groups (p>0.05). The rates of the patient satisfaction with the procedure were 93.4% in the TVT group versus 95.0% in the TVT-O group (p>0.05). Mean operation time (11.5±1.4 min versus 15.2±1.8 min, p<0.05) was significantly shorter in the TVT-O than TVT. There were no long-term complications, such as vaginal erosion and prolonged voiding difficulty, in either group. Conclusion: TVT-O appears to be equally effective as TVT for the surgical treatment of stress urinary incontinence in women at a 1-year follow-up. (J. Korean Continence Society 2005;9:108-114)

Comparative Analysis of the Efficacy and Safety of Conventional Transurethral Resection of the Prostate, Transurethral Resection of the Prostate in Saline (TURIS), and TURIS-Plasma Vaporization for the Treatment of Benign Prostatic Hyperplasia: A Pilot S

이용택,류영우,이동민,박상욱,염승희,한준현 대한비뇨의학회 2011 Investigative and Clinical Urology Vol.52 No.11

Purpose: This study was conducted to perform a comparative analysis of the efficacy and safety of conventional transurethral resection of the prostate (TUR-P), transurethral resection in saline (TURIS), and TURIS-plasma vaporization (TURIS-V) when performed by a single surgeon for benign prostatic hyperplasia (BPH). Materials and Methods: The clinical data of 73 consecutive men who underwent conventional TUR-P (39), TURIS (19), or TURIS-V (15) for BPH were retrospectively analyzed. All procedures were carried out by a single surgeon between October 2007 and April 2010. The patients were assessed preoperatively and perioperatively and were followed at 1, 3, and 6 months postoperatively. Patient baseline characteristics, perioperative data, and postoperative outcomes were compared, and major complications were recorded. Results: In all groups, significant improvements in subjective and objective voiding parameters were achieved and were sustained throughout follow-up. TURIS-V had the shortest operation time compared with conventional TUR-P and TURIS (p=0.211). TURIS-V significantly decreased procedural irrigation fluid volume, postoperative irrigation duration, catheter duration, and hospital stay compared with conventional TUR-P and TURIS. There were no significant differences between the groups in hemoglobin levels or serum sodium levels before and after the operations. There were three transfusions and four clot retentions in the TUR-P group, and one transfusion and one clot retention in the TURIS group. The TURIS-V group had no complications. Conclusions: TURIS and TURIS-V were effective for the surgical treatment of BPH in addition to conventional TUR-P. TURIS-V was not inferior to conventional TUR-P or TURIS in terms of safety.

A Predictive Factor in Overactive Bladder Symptoms Improvement after Combined Anterior Vaginal Wall Prolapse Repair: A Pilot Study

이동민,류영우,이용택,안승현,한준현,염승희 대한비뇨의학회 2012 Investigative and Clinical Urology Vol.53 No.6

Purpose: We aimed to determine whether a preoperative urodynamic parameter is a valuable predictor for the persistence of OAB symptoms after the AVP repair. Materials and Methods: 65 OAB patients with concomitant POP-Q stage III, IV anterior vaginal wall prolapse underwent a surgical repair were involved. All the patients were subjected to a preoperative urodynamic study, for whom the OABSS on questionnaire were preoperatively recorded. We firstly analyzed the correlation between the BOOI and the OABSS, then randomly divided patients into two groups: the group A (high PdetQmax, BOOI≥20) and the group B (low PdetQmax, BOOI<20). In each group, the OABSS was repeatedly measured post-operatively and the change were analyzed. Results: 31 patients were classified as the group A and 34 patients were classified as the group B. The group B showed significant decrease of symptom score in daytime frequency (p<0.01), urgency (p=0.04), urge incontinence (p=0.03), nocturnal frequency (p=0.01) and total score (p=0.01). The group A showed no significant decrease of symptom score in daytime frequency (p=0.42), urgency (p=0.61), urge incontinence (p=0.3), total score (p=0.15) except nocturnal frequency (p=0.01). Conclusions: A preoperative pressure-flow study can be a valuable tool in predicting the OAB symptoms change after the combined AVP repair. While the AVP repair leads to the improvement of OAB symptoms generally, some patients with a higher preoperative PdetQmax are still in need of the additional medical treatment. Purpose: We aimed to determine whether a preoperative urodynamic parameter is a valuable predictor for the persistence of OAB symptoms after the AVP repair. Materials and Methods: 65 OAB patients with concomitant POP-Q stage III, IV anterior vaginal wall prolapse underwent a surgical repair were involved. All the patients were subjected to a preoperative urodynamic study, for whom the OABSS on questionnaire were preoperatively recorded. We firstly analyzed the correlation between the BOOI and the OABSS, then randomly divided patients into two groups: the group A (high PdetQmax, BOOI≥20) and the group B (low PdetQmax, BOOI<20). In each group, the OABSS was repeatedly measured post-operatively and the change were analyzed. Results: 31 patients were classified as the group A and 34 patients were classified as the group B. The group B showed significant decrease of symptom score in daytime frequency (p<0.01), urgency (p=0.04), urge incontinence (p=0.03), nocturnal frequency (p=0.01) and total score (p=0.01). The group A showed no significant decrease of symptom score in daytime frequency (p=0.42), urgency (p=0.61), urge incontinence (p=0.3), total score (p=0.15) except nocturnal frequency (p=0.01). Conclusions: A preoperative pressure-flow study can be a valuable tool in predicting the OAB symptoms change after the combined AVP repair. While the AVP repair leads to the improvement of OAB symptoms generally, some patients with a higher preoperative PdetQmax are still in need of the additional medical treatment.

전립선비대증 환자의 수술적 치료에서 경요도 양극성 플라즈마 전립선기화술의 초기경험

이용택(Yong Taec Lee),이동민(Dong Min Lee),류영우(Young Woo Ryu),임송원(Song Won Lim),염승희(Seung Hee Yum),한준현(June Hyun Han) 대한비뇨기종양학회 2011 대한비뇨기종양학회지 Vol.9 No.3

Purpose: This study was conducted to introduce the initial experiences with transurethral bipolar plasma vaporization of the prostate (TBPVP) using ‘mushroom’ vapo-resection electrode for the treatment of benign prostatic hyperplasia (BPH) in Korean men. Materials and Methods: We retrospectively analysed the clinical data of 42 consecutive patients underwent TBPVP performed by a single surgeon between October 2009 and April 2011. The patients were assessed preoperatively and perioperatively, and were followed at 2, 4, and 8 weeks postoperatively. Patient baseline characteristics, perioperative data, postoperative outcomes, and major complications were recorded. Results: The mean age at surgery was 70.93±6.26 years. The mean prostate size was 64.10±17.83ml. The mean operation time was 59.40±25.99min, and the mean irrigation fluid volume during procedure was 26,000±10,511ml. The mean duration of catheterization was 3.57±0.94 days. The blood loss was minimal, and there was only 1 transfusion for the patient with ongoing heparization. Compared with baseline, there were significant improvements in IPSS, QoL, Qmax and postvoiding residual urine after surgery. Conclusions: The new TBPVP showed good short-term safety and efficacy for the treatment of Korean patients with BPH.