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증례 : 순환기 ; 약물 용출성 스텐트에서 발견된 신생내막 석회화 1예
양영준 ( Young June Yang ),심재민 ( Jae Min Shim ),김중선 ( Jung Sun Kim ),고영국 ( Young Guk Ko ),최동훈 ( Dong Hoon Choi ),장양수 ( Yang Soo Jang ),홍명기 ( Myeong Ki Hong ) 대한내과학회 2011 대한내과학회지 Vol.81 No.1
본 증례는 ST 분절 상승의 심근경색으로 약물 용출성 스텐트를 삽입한 환자에서 4년 후 발견된 스텐트 내강 안쪽을 둘러싼 원형의 두꺼운 석회침착소견에 대하여 신생내막과 관련된 새로운 죽상동맥경화증으로 추정하여 보고하는 바이다. Neointimal hyperplasia is the main mechanism of stent restenosis. Therefore, drug-eluting stents have replaced bare metal stents because there is less neointima and scar formation. Recently, some cases of stent restenosis after using a bare metal stent were found to involve calcification, not neointimal hyperplasia, and regarded as de novo atherosclerosis. We report unusual circular calcification inside a drug-eluting stent, which we called neointimal calcification. (Korean J Med 2011;81:98-101)
김석범(Seok Beom Kim),양영준(Young June Yang),황정호(Jung Ho Hwang),백승국(Seung Kuk Baek),김용복(Yong Bok Kim) 대한두경부종양학회 2002 대한두경부 종양학회지 Vol.18 No.2
A myoepithelial carcinoma, a rare malignant salivary gland neoplasm, occurs mostly in the parotid gland. The incidence of myoepithelioma is less than 1% of all salivary gland tumors, and malignant myoepithelioma is even more rare. Biological behavior of myoepithelial carcinoma has not been fully clarified. Malignant myoepithelioma shows clinicopathologic diversity and presents with various stages of myoepithelial differentiation. The definite treatment for malignant myoepithelioma is surgical excision, and the role of radiation therapy and chemotherapy is not yet established. In this study, we have experienced two patients with malignant myoepithelioma of the parotid gland who were treated with surgical excision.
사람면역결핍바이러스 감염 환자의 폐동맥 고혈압 발생빈도 및 임상양상
김미현 ( Mi Hyun Kim ),장혁재 ( Hyuk Jae Chang ),양영준 ( Young June Yang ),홍지영 ( Ji Young Hong ),강민경 ( Min Kyoung Kang ),양우인 ( Woo In Yang ),심지영 ( Chi Young Shim ),하종원 ( Jong Won Ha ),정남식 ( Nam Sik Chung ),신소 대한내과학회 2011 대한내과학회지 Vol.81 No.6
Background/Aims: Human immunodeficiency virus-associated pulmonary arterial hypertension (HIV-PAH) is a complication of HIV infection. Due to improvements in HIV survival rates following the introduction of highly active antiretroviral therapy, HIV-PAH has become an important cause of HIV-related morbidity. Thus, the objective of this study was to explore the prevalence and characteristics of HIV-PAH. Methods: Ninety-two patients were enrolled in the study from March to August 2010. We investigated clinical characteristics and performed echocardiography. HIV-PAH was defined as having a mean pulmonary arterial pressure (mPAP)≥25 mmHg based on Mahan`s equation, without lung disease or heart disease. The HIV-PAH-possible group was defined as having a tricuspid regurgitation velocity (TRV) of 2.9-3.4 m/s and a pulmonary arterial systolic pressure (PASP) of 37-50 mmHg. Results: Fifteen patients (16.3%) met the criteria of HIV-PAH based on mPAP. With respect to TRV, six patients met the criteria of the HIV-PAH-possible group. Based on the criteria of mPAP, the duration of HIV infection was not different with or without HIV-PAH. HIV RNA titers and CD4 T cell counts tended to be higher in HIV-PAH patients (8,607±11 vs. 1,067±64 copies/mL, p=0.371; 471±148 vs. 499±252 cells/mm3, p=0.680, respectively). Echocardiographic indices of the right ventricle were significantly deteriorated in the HIV-PAH group as compared with the non-HIV-PAH group (TASPE: 20.52 vs. 23.2, p=0.001; Tei index: 0.42 vs. 0.39, p=0.037). In a multivariate regression analysis, HIV activity factors (HIV duration, HIV RNA titer, and CD4 cell count) were not associated with echocardiographic indices of PAH (mPAP, PASP, and pulmonary vascular resistance). Conclusions: In this study, the prevalence of HIV-PAH was comparable to that of previous studies. (Korean J Med 2011; 81:729-739)