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심찬섭,이영숙,현창옥,최진수,이진관,서석조,이동화 ( Chan Sup Sim,Young Sook Lee,Chang Ok Hyun,Jin Soo Choi,Jin Kwan Lee,Succ Jo Suh,Dong Hwa Lee ) 대한소화기학회 1980 대한소화기학회지 Vol.12 No.1
Gilberts syr.drome is a condition which has been called idiopathic unconjugated hyperbili rubinemia, constitutional hepatic dysfuction or familial non-hemolytic jaundice with the characteristics of a benign, persistent but variable elevation of the plasma unconjugated bilirubin. A 2g-year old Korean male was admitted due to intermittent jaundice, indigestion, and general malaise. Physical examination revealed icteric sclera, but no hepatosplenmegaly. Laboratory findings showed increased serum bilirubin with indirect reacting bilirubin predo- minating. Percutaneous needle biopsy specimen of liver showed no special abnormalities. Calory deprivation test with caloric intake of 400 Cal a day for 72 hours resulted in a significant increase in the plasma bilirubin concentration (especially indirect form) in this patient. A brief review of the pertinent literature was made.
악성 폐쇄성황달에 대한 각종 내시경적 역행성담관배액법 ( ERBD ) 비교 평가
심찬섭(Chan Sup Shim),조영덕(Young Deok Cho),문종호(Jong Ho Moon),이영홍(Young Hong Lee),김진오(Jin Oh Lee),봉형근(Hyung Keun Bong),조주영(Joo Young Cho),김연수(Yun Soo Kim),이준성(Joon Seong Lee),이문성(Moon Sung Lee) 대한내과학회 1998 대한내과학회지 Vol.54 No.4
N/A Objectives : Endoscopic biliary drainage has been established as the palliative treatment of choice for malignant obstructive jaundice. At present, the major drawback of endoscopic biliary stenting is occlusion of the endoprosthesis with sludge, resulting in recurrence of jaundice or cholangitis. Recently, there are variable stents that have different materials, sizes, and designs have been used in efforts to overcome this problem To determine the success rate of stent insertion, successful drainage rate, duration of patency, complications related to stent insertion, and cause of stent malfunction, plastic endoprosthesis compared to metal stents in palliative treatment of malignant biliary obstruction. Method: We retrospectively evaluated 157 patients (total number of stent insertion: 308 cases) with unresectable malignant biliary obstruction to receive either a plastic stent(group I, 261 cases) or metal stent(group II, 47 cases). The patients who were recieved plastic stent were subdivided to general plastic stents(group Ia, polyethylene, polyurethane, polyvinylchloride, 225 cases) and Tannenbaum stent(group 1b, Teflon, 36 times) group. And the patients who were received metal stent were subdivided to uncovered metal stents(group IIa, Gianturco- Rosch, Wall, Strecker, EndoCoil stent, 26 times) and membrane covered self-expandable metal stent(group Ilb, 21 cases) group. Results 1) There were no statistical difference in successful rate of stent insertion and drainage effect of stent according to the types of stent(p>0.05). 2) Median patency of the stent was significantly prolonged in patients with a metal stent(group II) compared with those with a plastic stent(group I) (249 vs 123 days; p < 0.05). Median patency of the gorup Ib was significantly prolonged than those of group Ia(137 vs 109 days ; P < 0.05), but there was no statistical difference in median patency between group IIa and Ilb(233 vs 267 days; p > 0.05). 3) The rate of early complication related to stent insertion showed no significant difference in plastic and metal stent groups(P > 0.05). 4) Major causes of stent malfunction in plastic and metal stent were sludge(90% vs 21,4%), tumor ingrowth (4.4% vs 71.4%), and dislocation(5.6% vs 7.2%), respectively. Conclusion : Metal stents have a longer patency than plastic stent in patients with malignant biliary obstruction. In plastic stents, Tannenbaum stents have a slighlty longer patency than other plastic stents, but there were no differences in the success rates, drainage effect and complication rates according to types of stents.
심찬섭(Chan Sup Sim),이성원(Sung Won Lee),손무영(Moo Young Sohn),김진숙(Jean Sook Kim),한명동(Myung Dong Han),백정민(Cheong Min Paik) 대한소화기학회 1981 대한소화기학회지 Vol.13 No.2
Rotor syndrame is a familial disorder characterized by chronic, nonhemolytic, and predominantly conjugated hyperbilirubinemia with normal liver tissue without any pigment deposit in the liver cells. A 36-year-old Korean female was admitted due to intermittent jaundice, indigestion and general malaise. Physical examination revealed icteric sclera, but no hepatomegaly. Laboratory findings showed increased serum bilirubin with direct reacting bilirubin predominating and prolonged BSP retention (32% in 45 min.) Oral cholecystography revealed well-visualization but intravenous cholangiography did not reveal the gall bladder and the duct, Percutaneous needle biopsy specimen of liver showed no special abnormalities. Urinary total coproporphyrin excreation was increased. A brief review of the pertinent literature was made.
심찬섭(Chan Sup Sim),백정민(Cheong Min Paik),조한성(Han Sung Cho),변희섭(Hee Sup Byun),박동철(Dong Chul Park) 대한소화기학회 1982 대한소화기학회지 Vol.14 No.1
N/A A clinical observation was made on the 104 cases of the acute pancreatitis confirmed by the clinical and laboratory findings and treated at the Soon Chun Hyang Hospital as in- patients during the 7-year period from May, 1974 to December, 1980 The results of the observation were as follows; 1) In sex distribution, there were 58 males and 46 females of 104 cases, and there was a slight predominance of the male showing the male to female ratio about 4: 3. In age distribution the disease was most commonly seen in the 5th. Decade(26%), 2) The possible etiologic factors of the disease were unknown origin(43.2%), overeating and alcohol(15.4%), biliary tract disease(11.5%) in order. In the minority of the patients, ascariasis, peptic ulcer, infection, duodenal diverticulum, pregnancy, diabetes or oral Contraceptive pills were suspected as the possible etiologic factors. 3) In symptomatology the patients complained of upper abdominal pain, nausea and vomiting and fever with chills in order. The most commonly observed physical sign was tenderness in the upper abdomen. Decreased bowel movement, abdominal muscular rigidity and jaundice were also noticed. 4) C.B.C. showed leukocytosis(36.5%) and blood chemistry showed hypoalbuminemia(5.4%) hyperbilirubinemia(28.6%), elevated values of alkaline phosphatase(23.1%) and S.G.O.T. (34. 4%), hyperglycemia(25. 8%) and hypocalcemia(26%). 5) In the radiological studies chest roentgenogram showed abnormal findings(21. 7%) and simple flat plate abdomen showed paralytic ileus(55.6%). Oral cholecystography and intravenous cholangiography revealed nonvisualization of gall bladder(20.5%) and biliary trees(21.1%) and gall stones(11%).
심찬섭 ( Chan Sup Shim ) 대한소화기학회 2005 대한소화기학회지 Vol.45 No.3
Photodynamic therapy (PDT) was first used for the treatment of esophageal cancer in early 1980s, Since then, numerous applications have been reported for its use in gastrointestinal tract including Barrett`s esophagus, gastric, duodenal, biliary, pancreat