Metal Artifact Reduction for Orthopedic Implants: Brain CT Angiography in Patients with Intracranial Metallic Implants

선우준,박선원,임정효,강연아,정영섭,손영제,김수진 대한의학회 2018 Journal of Korean medical science Vol.33 No.21

Background: The purpose of this study was to qualitatively and quantitatively evaluate the effects of a metal artifact reduction for orthopedic implants (O-MAR) for brain computed tomographic angiography (CTA) in patients with aneurysm clips and coils. Methods: The study included 36 consecutive patients with 47 intracranial metallic implants (42 aneurysm clips, 5 coils) who underwent brain CTA. The computed tomographic images with and without the O-MAR were independently reviewed both quantitatively and qualitatively by two reviewers. For quantitative analysis, image noises near the metallic implants of non-O-MAR and O-MAR images were compared. For qualitative analysis, image quality improvement and the presence of new streak artifacts were assessed. Results: Image noise was significantly reduced near metallic implants (P < 0.01). Improvement of implant-induced streak artifacts was observed in eight objects (17.0%). However, streak artifacts were aggravated in 11 objects (23.4%), and adjacent vessel depiction was worsened in eight objects (17.0%). In addition, new O-MAR-related streak artifacts were observed in 32 objects (68.1%). New streak artifacts were more prevalent in cases with overlapping metallic implants on the same axial plane than in those without (P = 0.018). Qualitative assessment revealed that the overall image quality was not significantly improved in O-MAR images. Conclusion: In conclusion, the use of the O-MAR in patients with metallic implants significantly reduces image noise. However, the degree of the streak artifacts and surrounding vessel depiction were not significantly improved on O-MAR images.

동 (銅) 의 동적 (動的) 재결정화 (再結晶化)

선우준,황인철 대한금속재료학회 1993 대한금속재료학회 학술대회 개요집 Vol.1993 No.0

Efficacy of Maximum Intensity Projection of Contrast-Enhanced 3D Turbo-Spin Echo Imaging with Improved Motion-Sensitized Driven-Equilibrium Preparation in the Detection of Brain Metastases

배윤정,최병세,이경미,윤연홍,선우준,정철규,김재형 대한영상의학회 2017 Korean Journal of Radiology Vol.18 No.4

Objective: To evaluate the diagnostic benefits of 5-mm maximum intensity projection of improved motion-sensitized driven-equilibrium prepared contrast-enhanced 3D T1-weighted turbo-spin echo imaging (MIP iMSDE-TSE) in the detection of brain metastases. The imaging technique was compared with 1-mm images of iMSDE-TSE (non-MIP iMSDE-TSE), 1-mm contrast-enhanced 3D T1-weighted gradient-echo imaging (non-MIP 3D-GRE), and 5-mm MIP 3D-GRE. Materials and Methods: From October 2014 to July 2015, 30 patients with 460 enhancing brain metastases (size > 3 mm, n = 150; size ≤ 3 mm, n = 310) were scanned with non-MIP iMSDE-TSE and non-MIP 3D-GRE. We then performed 5-mm MIP reconstruction of these images. Two independent neuroradiologists reviewed these four sequences. Their diagnostic performance was compared using the following parameters: sensitivity, reading time, and figure of merit (FOM) derived by jackknife alternative free-response receiver operating characteristic analysis. Interobserver agreement was also tested. Results: The mean FOM (all lesions, 0.984; lesions ≤ 3 mm, 0.980) and sensitivity ([reader 1: all lesions, 97.3%; lesions ≤ 3 mm, 96.2%], [reader 2: all lesions, 97.0%; lesions ≤ 3 mm, 95.8%]) of MIP iMSDE-TSE was comparable to the mean FOM (0.985, 0.977) and sensitivity ([reader 1: 96.7, 99.0%], [reader 2: 97, 95.3%]) of non-MIP iMSDE-TSE, but they were superior to those of non-MIP and MIP 3D-GREs (all, p < 0.001). The reading time of MIP iMSDE-TSE (reader 1: 47.7 ± 35.9 seconds; reader 2: 44.7 ± 23.6 seconds) was significantly shorter than that of non-MIP iMSDE-TSE (reader 1: 78.8 ± 43.7 seconds, p = 0.01; reader 2: 82.9 ± 39.9 seconds, p < 0.001). Interobserver agreement was excellent (κ > 0.75) for all lesions in both sequences. Conclusion: MIP iMSDE-TSE showed high detectability of brain metastases. Its detectability was comparable to that of non-MIP iMSDE-TSE, but it was superior to the detectability of non-MIP/MIP 3D-GREs. With a shorter reading time, the false-positive results of MIP iMSDE-TSE were greater. We suggest that MIP iMSDE-TSE can provide high diagnostic performance and low false-positive rates when combined with 1-mm sequences.

Differentiation of Deep Subcortical Infarction Using High-Resolution Vessel Wall MR Imaging of Middle Cerebral Artery

배윤정,최병세,정철규,윤연홍,선우준,배희준,김재형 대한영상의학회 2017 Korean Journal of Radiology Vol.18 No.6

Objective: To evaluate the utility of high-resolution vessel wall imaging (HR-VWI) of middle cerebral artery (MCA), and to compare HR-VWI findings between striatocapsular infarction (SC-I) and lenticulostriate infarction (LS-I). Materials and Methods: This retrospective study was approved by the Institutional Review Board, and informed consent was waived. From July 2009 to February 2012, 145 consecutive patients with deep subcortical infarctions (SC-I, n = 81; LS-I, n = 64) who underwent HR-VWI were included in this study. The degree of MCA stenosis and the characteristics of MCA plaque (presence, eccentricity, location, extent, T2-high signal intensity [T2-HSI], and plaque enhancement) were analyzed, and compared between SC-I and LS-I, using Fisher’s exact test. Results: Stenosis was more severe in SC-I than in LS-I (p = 0.040). MCA plaque was more frequent in SC-I than in LS-I (p = 0.028), having larger plaque extent (p = 0.001), more T2-HSI (p = 0.001), and more plaque enhancement (p = 0.002). The eccentricity and location of the plaque showed no significant difference between the two groups. Conclusion: Both SC-I and LS-I have similar HR-VWI findings of the MCA plaque, but SC-I had more frequent, larger plaques with greater T2-HSI and enhancement. This suggests that HR-VWI may have a promising role in assisting the differentiation of underlying pathophysiological mechanism between SC-I and LS-I.

확률론적 해석에 기반한 다중 열저장공동의 적정 이격거리 분석

박도현(Dohyun Park),김현우(Hyunwoo Kim),박정욱(Jung-Wook Park),박의섭(Eui-Seob Park),선우준(Choon Sunwoo) 한국암반공학회 2014 터널과지하공간 Vol.24 No.2

다중 열저장공동은 열에너지의 대규모 저장, 열적 성능 향상을 위한 높은 종횡비의 저장소 설계에 활용될 수 있다. 또한 긴 터널형의 단일공동이 열생산 및 주입을 위한 지상설비와의 연결에 적합하지 않은 경우, 길이를 줄인 다중 암반공동의 활용을 고려할 필요가 있다. 다중 열저장공동 활용시 공동간의 이격거리는 저장공간 설계시 고려해야 하는 주요 설계인자 중 하나이며, 정량적인 안정성 평가기준을 토대로 적정 이격거리가 산정되어야한다. 본 논문에서는 대규모 열에너지 저장을 위한 다중 암반공동 계획시 공동간 이격거리를 결정하기 위한 수치해석적 접근법에 대해 기술하였다. 다중 암반공동의 안정성 평가를 위해 기존의 결정론적 접근법과 달리 확률밀도에 의해 입력 매개변수의 불확실성을 정량적으로 고려할 수 있는 확률론적 해석기법을 이용하였으며, 집단열수공급을 위한 다중 암반공동의 개념모델 설계에 적용하였다. 본 적용을 통해 확률론적 해석기법이 다중 암반공동의 이격거리 산정을 위한 의사결정 도구로서 유용하게 활용될 수 있음을 확인할 수 있었으며, 결정론적 해석결과와의 비교 분석으로부터 결정론적 접근법 적용시 안정성 평가기준을 신중히 설정할 필요가 있는 것으로 검토되었다. Multiple thermal energy storage (TES) caverns can be used for storing thermal energy on a large scale and for a high-aspect-ratio heat storage design to provide good thermal performance. It may also be necessary to consider the use of multiple caverns with a reduced length when a single, long tunnel-shaped cavern is not suitable for connection to aboveground heat production and injection equipments. When using multiple TES caverns, the separation distance between the caverns is one of the significant factors that should be considered in the design of storage space, and the optimal separation distance should be determined based on a quantitative stability criterion. In this paper, we described a numerical approach for determining the optimal separation distance between multiple caverns for large-scale TES utilization. For reliable stability evaluation of multiple caverns, we employed a probabilistic method which can quantitatively take into account the uncertainty of input parameters by probability distributions, unlike conventional deterministic approaches. The present approach was applied to the design of a conceptual TES model to store hot water for district heating. The probabilistic stability results of this application demonstrated that the approach in our work can be effectively used as a decision-making tool to determine the optimal separation distance between multiple caverns. In addition, the probabilistic results were compared to those obtained through a deterministic analysis, and the comparison results suggested that care should taken in selecting the acceptable level of stability when using deterministic approaches.

Fully Automatic Segmentation of Acute Ischemic Lesions on Diffusion-Weighted Imaging Using Convolutional Neural Networks: Comparison with Conventional Algorithms

Ilsang Woo,Areum Lee,Seung Chai Jung,Hyunna Lee,Namkug Kim,조세진,Donghyun Kim,Jungbin Lee,선우준,Dong-Wha Kang 대한영상의학회 2019 Korean Journal of Radiology Vol.20 No.8

Objective: To develop algorithms using convolutional neural networks (CNNs) for automatic segmentation of acute ischemic lesions on diffusion-weighted imaging (DWI) and compare them with conventional algorithms, including a thresholding-based segmentation. Materials and Methods: Between September 2005 and August 2015, 429 patients presenting with acute cerebral ischemia (training:validation:test set = 246:89:94) were retrospectively enrolled in this study, which was performed under Institutional Review Board approval. Ground truth segmentations for acute ischemic lesions on DWI were manually drawn under the consensus of two expert radiologists. CNN algorithms were developed using two-dimensional U-Net with squeeze-and-excitation blocks (U-Net) and a DenseNet with squeeze-and-excitation blocks (DenseNet) with squeeze-and-excitation operations for automatic segmentation of acute ischemic lesions on DWI. The CNN algorithms were compared with conventional algorithms based on DWI and the apparent diffusion coefficient (ADC) signal intensity. The performances of the algorithms were assessed using the Dice index with 5-fold cross-validation. The Dice indices were analyzed according to infarct volumes (< 10 mL, ≥ 10 mL), number of infarcts (≤ 5, 6–10, ≥ 11), and b-value of 1000 (b1000) signal intensities (< 50, 50–100, > 100), time intervals to DWI, and DWI protocols. Results: The CNN algorithms were significantly superior to conventional algorithms (p < 0.001). Dice indices for the CNN algorithms were 0.85 for U-Net and DenseNet and 0.86 for an ensemble of U-Net and DenseNet, while the indices were 0.58 for ADC-b1000 and b1000-ADC and 0.52 for the commercial ADC algorithm. The Dice indices for small and large lesions, respectively, were 0.81 and 0.88 with U-Net, 0.80 and 0.88 with DenseNet, and 0.82 and 0.89 with the ensemble of U-Net and DenseNet. The CNN algorithms showed significant differences in Dice indices according to infarct volumes (p < 0.001). Conclusion: The CNN algorithm for automatic segmentation of acute ischemic lesions on DWI achieved Dice indices greater than or equal to 0.85 and showed superior performance to conventional algorithms.