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      • KCI등재

        Left Ventricular Noncompaction in Adults: Imaging and Clinical Findings in 63 Patients

        조세진,양동현,강준원,임태환 대한영상의학회 2018 대한영상의학회지 Vol.78 No.3

        Purpose: To describe imaging and clinical findings for a left ventricular noncompaction (LVNC) in the adult. Materials and Methods: From 2000 to 2014, 63 patients were diagnosed with LVNC by echocardiography, computed tomography, and magnetic resonance imaging at our hospital. Baseline characteristics, clinical manifestations, combined cardiac or systemic anomalies, and imaging findings were reviewed. We made a comparison between the isolated and combined disease groups. Results: Among 63 patients with LVNC, 32 (51%) patients did not have combined cardiac anomalies (isolated disease group). The mean age at the initial diagnosis was higher in the isolated than in the combined disease group (54.2 years vs. 40.2 years, p < 0.001). The combined disease group presented symptoms more frequently at initial diagnosis than the isolated disease group (94% vs. 75%, p = 0.082). Heart failure symptoms were the most common adverse events (60.3% in all patients). Thromboembolic events developed in 20 patients, and were more frequent in the combined disease group than in the isolated disease group (39% vs. 26%, p = 0.279). The most common cardiac abnormality was dilated cardiomyopathy (n = 15, 24%). There was no significant difference in the mean noncompacted/compacted ratios between both of the disease groups. Conclusion: Isolated and combined LVNC disease groups showed differences in age at diagnosis and clinical manifestations. The clinical and imaging findings may be helpful to better understand LVNC.

      • KCI등재

        Anti-Adipogenic and Anti-Obesity Effects of Gongmi Tea and Gongmi So Extract

        조세진,Yue Gong,Rui Jiang,정현재,김영란 한국식품영양과학회 2023 Preventive Nutrition and Food Science Vol.28 No.1

        The prevalence of obesity has been increasing worldwide, and its pathogenesis is closely related to preadipocyte differentiation. Because the presence of obesity increases the risk of chronic disease, it is important to decrease excessive body fat accumulation. This study aimed to demonstrate the anti-adipogenesis and anti-obesity effects of gongmi tea and gongmi so extract. The 3T3-L1 preadipocyte cell line was stained with Oil red O, and the expression levels of peroxisome proliferator-activated receptor-γ (PPARγ), adiponectin, and fatty acid-binding protein 4 (FABP4) were evaluated via Western blot analysis. A mouse model of obesity was developed by feeding C57BL/6 male mice a high-fat diet (HFD). Gongmi tea or gongmi so extract was orally administered at a dose of 200 mg/kg for 6 weeks. The mouse body weight was measured weekly during the study period, and the epididymal adipose tissue weight and blood serum were analyzed at the end of the study period. The gongmi tea and gongmi so extract did not exhibit toxicity in mice. Oil red O staining showed that gongmi tea significantly decreased excessive body fat accumulation. In addition, gongmi tea (300 mg/mL) significantly downregulated adipogenic transcription factors, such as PPARγ, adiponectin, and FABP4. In vivo tests indicated that oral administration of gongmi tea or gongmi so extract to C57BL/6 mice with HFD-induced obesity effectively decreased their body weight and epididymal adipose tissue. Gongmi tea and gongmi so extract have potent in vitro anti-adipogenic effects in 3T3-L1 cells and in vivo anti-obesity effects in mice with HFD-induced obesity.

      • KCI등재

        재일코리안 교육의 패러다임 전환과 경험 - 코리아국제중고등학교 졸업생 3인의 구술사를 중심으로 -

        조세진 한양대학교 일본학국제비교연구소 2021 비교일본학 Vol.52 No.-

        본 연구는 코리아국제중고등학교의 사례를 중심으로 재일코리안 민족교육의 패러다임이 변화하고 있는 현황을 살펴보고 이러한 변화의 저변에 있는 교육적 수요에 대해 분석한다. 재일코리안 민족학교의 역사적 전개에서는 내셔널리즘의 영향이 존재해 왔으며 이는 분리주 의적 학교 환경의 형성에 영향을 미쳤다. 2008년 설립된 코리아국제중고등학교는 재일코리안 교육에서 내셔널리즘의 영향을 극복하고 트랜스내셔널리즘에 기반한 교육을 실현하기 위해 설립되었다. 본 연구는 재일코리안 민족교육의 최대 학교군인 조선학교를 졸업하고 이후 코 리아국제중고등학교에서 수학한 젊은 세대 재일코리안 3인의 구술사를 통해, 이들이 재일코 리안으로서의 에스닉 정체성과 동시에 일본사회 구성원으로서의 정체성을 지향하고 있으며 이러한 인식이 조선학교에서 코리아국제중고등학교로 학교를 전환하는 선택으로 이어졌음을 고찰한다. 본 연구를 통해서는 민족교육 패러다임의 변화의 저변에 존재하는 인식의 특징을 확인할 수 있다. This paper explores the change of educational paradigm of Zainichi Korean education in Japan with the example of Korea International School (KIS). In the history of ethnic minority schooling for Zainich Koreans, it is noticeable that nationalism had influenced their curriculum. To overcome nationalistic ideas in the education of ethnic schools, KIS was established in 2008 based on the idea of transnationalism. This paper explores the experiences of three students who started their education in a Chōsen school, which is the biggest group of the Zainichi Korean school, and then transferred to KIS. This paper examines interviewees’ educational desire in their choice of changing schools. Their identity as a Korean ethnic minority and also as a member of Japanese society could not be fully explored in a Chōsen school. Through this analysis, this paper shows one of the underlying reasons for the change of educational paradigm of the Zainichi Korean school.

      • KCI등재

        태아 수종증의 임상 양상

        조세진,전종관 대한산부인과학회 2000 Obstetrics & Gynecology Science Vol.43 No.8

        Objective : Our objective is to evaluate clinical aspects of hydrops fetalis, which is classified as immune and nonimmune. Materials and Methods : From Oct. 1988 to Nov. 1997, 44 pregnant women were evaluated with various tests, including cordocentesis, fetal echocardiography, and detailed ultrasonography for the indication of ultrasonographically detected fetal hydrops or suspected fetal hydrops. Maternal mean age(±standard deviation) was 29.3(±2.8) years and gestational age was within the range of 16 weeks and 37 weeks. Results : Of 44 cases, 4 cases (9.1%) were immune hydrops, 40 cases (90.9%) were nonimmune hydrops. Fetal transfusion was done to 4 immune hydrops. Of 4 transfused fetus, 2 fetuses died within 12 hours of transfusion, and survival rate after intrauterine transfusion was 50% (2/4). Seven cases had chromosomal abnormalities(18.9%, 7/37), ten cases (25%) had cystic hydroma, seven cases (17.5%) had cardiac anomaly, three cases (7.5%) had fetal infection. Excluding 2 cases of follow-up loss, eight cases of stillbirth and four cases of pregnancy termination, five cases survive beyond neonatal period. Conclusion : Our experiences show that fetal transfusion for immune hydrops can be tried in the cases remote from term and prognosis of nonimmune hydrops is dismal in spite of aggressive work-up for identifying causes.

      • KCI등재

        Long-Term Results of Thermal Ablation of Benign Thyroid Nodules: A Systematic Review And Meta-Analysis

        조세진,백정환,정새롬,최영준,이정현 대한내분비학회 2020 Endocrinology and metabolism Vol.35 No.2

        Background: Ultrasound-guided thermal ablations have become one of the main options for treating benign thyroid nodules. To determine efficacy of thermal ablation of benign thyroid nodules, we performed a meta-analysis of studies with long-term follow-up ofmore than 3 years. Methods: Databases were searched for studies published up to August 25, 2019, reporting patients with benign thyroid nodulestreated with thermal ablation and with follow-up data of more than 3 years. Data extraction and quality assessment were performedaccording to PRISMA guidelines. The analysis yielded serial volume reduction rates (VRRs) of ablated nodules for up to 3 years ormore, and adverse effect of ablation during follow-up. Radiofrequency ablation (RFA) and laser ablation (LA) were compared in asubgroup analysis. Results: The pooled VRRs for ablated nodules showed rapid volume reduction before 12 months, a plateau from 12 to 36 months,and more volume reduction appearing after 36 months, demonstrating long-term maintenance of treatment efficacy. Thermal ablation had an acceptable complication rate of 3.8%. Moreover, patients undergoing nodule ablation showed no unexpected delayedcomplications during the follow-up period. In the subgroup analysis, RFA was shown to be superior to LA in terms of the pooledVRR and the number of patients who underwent delayed surgery. Conclusion: Thermal ablations are safe and effective methods for treating benign thyroid nodules, as shown by a long follow-upanalysis of more than 3 years. In addition, RFA showed superior VRRs compared with LA for the treatment of benign thyroid nodules, with less regrowth and less delayed surgery.

      • KCI등재

        급성 허혈성 뇌졸중에서의 뇌 영상 검사의 최신 지견과 역할

        조세진,정승채,서종현,김경원,우동철,오우용,이종구,김병준 대한영상의학회 2019 대한영상의학회지 Vol.80 No.6

        Neuroimaging plays a key role in assessing the detection of acute hemorrhage, diagnosis of infarct core, detection of steno-occlusive arteries, mismatch between infarct core and penumbra, and collateral circulation in patients with acute cerebral ischemic stroke. The recent announcement of randomized clinical trials that demonstrated the usefulness of intra-arterial mechanical thrombectomy and the guidelines of 2018 Guidelines for the Early Management of Patients with Acute Ischemic Stroke from American Heart Association/American Stroke Association led to a larger role of neuroimaging and required new neuroimaging strategy for acute cerebral ischemic stroke. In this review, we summarize the recommendation on neuroimaging from the 2018 Guidelines, and review pros and cons between CT and MR and fast scanned stroke MR. Based on the new guidelines and recent research, we discuss the appropriate neuroimaging strategy for acute cerebral ischemic stroke patients. 뇌 영상 검사는 급성 허혈성 뇌졸중 환자의 뇌출혈 배제, 뇌경색 진단, 폐색 혈관의 검출, 관류상태와 뇌경색 간의 불일치 정도, 측부 순환 상태를 평가하는 핵심적인 역할을 한다. 최근 동맥 내 재개통술의 효용성을 증명한 무작위 배정 임상시험과 함께 이를 반영한 2018년 미국뇌졸중협회 가이드라인이 발표되면서 급성 허혈성 뇌졸중 환자의 진단과 치료 대상 선별을 위한 뇌 영상 검사의 역할은 더욱 커졌고 이에 시간에 따라 다른 영상의학적 전략이 중요해졌다. 이에 2018년 미국뇌졸중협회 가이드라인의 영상의학적 권고안을 요약하고 주요 뇌 영상검사인 CT와 MR의 역할과 장·단점 및 MR의 단점 극복을 위한 고속촬영 기법에 대해 기술하고자 한다. 아울러 새로운 가이드라인과 최근의 연구를 바탕으로 급성 허혈성 뇌졸중 환자를위한 적절한 영상의학적 전략에 대해 논하고자 한다.

      • KCI등재

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