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송진우 ( Song Jin U ),김명환 ( Kim Myeong Hwan ),서욱장 ( Seo Ug Jang ),오동렬 ( O Dong Lyeol ),김기덕 ( Kim Gi Deog ),문성훈 ( Mun Seong Hun ),양동훈 ( Yang Dong Hun ),송문희 ( Song Mun Hui ),이상수 ( Lee Sang Su ),서동완 ( Seo D 대한소화기학회 2003 대한소화기학회지 Vol.42 No.5
Eosinophilic pancreatitis is a rare disorder that may only be diagnosed after pancreatic resection under the suspection of a pancreatic tumor. We experienced a 65-year-old female patient whose initial presentation suggested pancreatic cancer. Radiologic evaluation revealed a pancreatic mass-like lesion which was obstructing the main pancreatic duct. Endoscopic retrograde cholangiopancreatography (ERCP) showed double duct strictures involving the distal common bile duct and the main pancreatic duct. Serum IgE level was elevated. Percutaneous core needle biopsy with an 18-gauge needle was performed targeting the pancreatic lesion. The biopsy specimen revealed fibrotic interlobular septum and intralobular fibrosis with prominent eosinophilic infiltration. The patient was treated with oral prednisolone (40 mg/day). A plastic stent was inserted into the narrowed common bile duct. After three months of oral steroid therapy, symptoms and signs improved rapidly and serum IgE level was decreased. Abdominal computed tomography and ERCP revealed remission of pancreatic mass-like lesion. (Korean J Gastroenterol 2003;42:444-449)