한 가족에서의 안인두근이양증 2예

서만욱,이광호,노재규,명호진 대한신경과학회 1984 대한신경과학회지 Vol.2 No.2

뇌졸중후 율동성 정좌불능증 1예

서만욱,오선영,성경미,신병수,김영현 대한임상신경생리학회 2002 Annals of Clinical Neurophysiology Vol.4 No.2

Dyskinesia con occur as a neurological abnormality due to stroke, and its incidence in stroke patients is reported be about 1%. It is possible to classify dyskinesia into one of the morphologic types already classified clinically. However, a specific type of dyskinesia can occur, one which does not fall into the existing morphologic types. We experienced sych a case of specific type dyskinesia, which couldn't be classified into the existing classification system. A 50-year-old man visited our hospital due to rhythmic dyskinesia of the right hand, which appeared during the resting state, and had developed one month after left subcortical infarction. Flexion and extension movements of the fingers at 3Hz appeared due to the impulse to move, however, this abnormal movement could be easily suppressed under the patients will. We suggested that the abnormal movement was similar to akathisia from the fact that if occurred due to the internal desire to move and that the patient could suppress dyskinesia. However, the rhythmic tendency and lack of medication history of antipsychotics suggested that the movement was not the typical form of akathisia. The present case may represent a new clinical type of movement disorder developed after stroke. Considering the clinical pattern of the present case and following a review of the literature, we believe that it can be labeled, post-stroke rhythmic akathisia.

노인성 구강-안면 이상운동증 4례와 병태 생리에 대한 고찰

서만욱 대한신경과학회 1998 대한신경과학회지 Vol.16 No.4

수면성 두통 2예

서만욱,오선영,이병용 대한신경과학회 2000 대한신경과학회지 Vol.18 No.6

이상운동 질환에서의 신경생리적 검사법의 유용성

서만욱,이광우 대한임상신경생리학회 1999 Annals of Clinical Neurophysiology Vol.1 No.2

In clinical neurology various different electrophysiological tests are widely used to demonstrate the unsuspected malfunctioning in the nervous system and to monitor over time the clinical status of patients. In addition clinical neurologists and neurosurgeons take advantage of the intraoperative monitorings to increase the quality of neurosurgical operations in the posterior fossa, in the spinal cord, or in visual pathways. In the field of movement disorders, electrophysiological tests provide neurologists with making accurate differential diagnoses with useful therapeutic tests it could be possible for us to evaluate the types of blephalospasm, the extent of hemifacial spasm, the level of myoclonus, and the prime muscle of torticollis etc. Sometimes the myographic guidance may be critical for choosing the exact injecting site of botulinum toxin. These several decades various electroencephalographic and evoked potential tests had been utilized in the electrophysiological laboratories to understand the basic pathophysiology of myoclonus, spasticity and other central motor dysfunctions. It could be one of the breakthroughs in the area of behavorial neurology that the brain function can be mapped by the spontaneous or evoked electrical activities of nervous system since the movement related potentials (MRPs) had been studies for several decades. Various reflex tests such as masseter reflex, blink reflex, click evoked vestibulocollic reflex, facial reflex, stretch reflex, flexor reflex, H-reflex recovery curve, vestibulbar inhibition of H-reflex, reciprocal inhibition, recurrent or Renshaw reflex, Ib inhibition, cutaneous reflex have been also used to understand normal or abnormal physiology in movement disorders. Polysomnography, posturography and gait studies are also applied in clinical neurology in association with movement disorders which are useful in deciding the treatment regimen.

CHAP 증후군 1예

서만욱,김지성,유성용,신병수,김영현 대한노인병학회 2001 대한노인병학회지 Vol.5 No.4

간대성 근경련의 분류와 전기생리적 평가

서만욱 대한임상신경생리학회 1999 Annals of Clinical Neurophysiology Vol.1 No.2

Myoclonus is a brief muscle jerk caused by neuronal discharge. Myoclonus can be classified from various points of view such as (1) clinical presentaiton; (2) neurophysiological origin; and (3) etiology. Among them, classification on the basis of the underlying pathophysiology is most reasonable. However underlying pathophysiologies of myoclonus have not been well known, evolving electrophysiologic studies aid in making the diagnosis and privide insight into the pathophysiology of myoclonus. Furthermore these Can differentiate myoclonus from other movement disorders, and positive from negative myoclonus; more importantly, these reveal the origin of the discharges producing the jerks. Myoclonus could be classified into two broad groups, epiletic and nonepiletic, according to the different electrophysiologic findings. Epiletic myoclonus could also be subclassified into several groups according to the location of the presumed generators suspected by current electrophysiologic findings

당뇨병 환자에서 배측 음경 신경병증과 감각성 다발신경병증과의 상관관계에 대한 연구

서만욱,김영현,백홍선,박종관 의과학연구소 1994 全北醫大論文集 Vol.18 No.1

Impairment of sexual function is common in male diabetic patients. This problem is generally attributed to a peripheral neuropathy involving the nerves controlling penile erection. Through the electrophysiological studies, it was proved that neuropathy of the terminal branch of the pudendal nerve is most responsible for the sexual dysfunction. In diabetic polyneuropathy, most distal sensory fibers are initially involved by dying back phenomenon. In addition to the frequent appearance of diabetic polyneuropathy with sexual dysfunction, this similar neuropathologic pattern led us to hypothesize that penile neuropathy could be a form of diabetic polyneuropathy. For the verification of this hypothesis, the degree of correlation between diabetic polyneuropathy and penile neuropathy was evaluated. The senso교 nerve conduction velocities of the dorsal nerve of the penis and sural nerve were recorded from 16 normal men and 16 diabetic patients with impotence. The sensory nerve conduction velocities of the dorsal nerves of the penis had a high interrelationship with that of sural nerves in diabetic patients. According to these results, it could be established that the penile neuropathy is a sort of diabetic polyneruopathy.

근수축성 두통세서의 상대휴지근전도치의 진단적 의의

서만욱,김영현 의과학연구소 1993 全北醫大論文集 Vol.17 No.2

The classical definition of muscle contraction headache implicates that this type of headache is characterized by substained contractions of muscles located in the frontotemporal or suboccipital regions. But the role of sustatined contractions of miscles located in the frontotemporal or suboccipital regions. But the role of sustained muscle contractions in this type of headache has not been clearly established. In comparison with normal control subjects, patients suffering from muscle contraction headache have been found to have significantly higher resting EMG levels. Non-significant differences, however, have been found more frequently. In all of previous studies, EMG has been measured in terms of absolute amplitude. Resting EMG amplitudes are dependent on the idiosyncratic, morphological, and physiological properties of muscle. EMG amplitudes are dependent on the idiosyncratic, morphological, and physhiological properties of muscles. This fact suggest that absolute resting EMG amplitudes be not good as a physiologic diagnostic criterion of muscle contration headache. Electrical stimulation of the muscle has been shown to result in a change towards a slower type of muscle with a higher proportion of type I fibers. It is conceivalble that similar processes occur in chronic headache patients which would exert long-term weak sustained ontrations of muscles of the head. Muscles with a high proportion of type I fibers would on the average, be expected to have a smaller amplitude of maximal contraction EMG levels than muscles with a low proportion. This assumption led us to hypothesize that the significantly higher EMG levels of muscle contraction headache could be recorded if the resting EMG levels were expressed as a percentage of the EMG level during maximal contraction. To demonstrate the diagnostic significance of this proportional resting EMG in the muscle contraction headache, we recorded it in the two groups of headache patients, that is, group I satisfied the physiologic criterion of muscle contraction headache, on the other hand, group Ⅱ did not satisfy the criterion based on the absolute resting EMG levels. The proportional resting EMG levels were significantly high in group Ⅱ as well as group Ⅰ. These results demonstrated that the proportional EMG levels are a better index of the state of muscle contraction than absolute resting EMG levels.

腦卒中의 疫學的 動向에 關한 硏究 : 特殊集團을 中心으로

서만욱,김영현 의과학연구소 1991 全北醫大論文集 Vol.15 No.3