Metrazol 유발뇌파검사의 意義(Ⅰ)

明好鎭 최신의학사 1974 最新醫學 Vol.17 No.7

To those who had an unexpected convulsion, it would be as fearful a catastrophe as typhoon or earthquake. They would also be anxious to know whether the nature of their convulsion has been epileptic, symptomatic or caused by functional (psychiatric) disorder. It is really regrettable that the EEGs of epileptic patients which have been normal in routine EEG study, only 70 to 80% are activated by the rarely life-threatening Metrazol provocation procedures. The author has studied the procedures by trying them again on the Korean and found a distinct age significance in the activation procedures. Out of total 76 activation procedure cases, as many as 9 experienced miserable unexpected clinical seizures. For both examiners and examinees and their siblings, development of a safer drugs which would not cause any clinical seizure and a procedure which would be handy with a provocation significance of no less than 103 are sincerely desired in the near future.

Pentylentetrazol 筋注誘發 腦波檢査의 誘發潛時의 測定

明好鎭 大韓神經精神醫學會 1979 신경정신의학 Vol.18 No.2

In tie latest years, the selection of inductees in Korea has turned more refined for national defense in terms of elitism, and along with a rapid industrialization, the demand for skilled technicians and engineers handling precision equipment, chemicals, explosives, and power-operated tools, machines and vehicles is increasing more than ever. It may be said that in pre-employment examination of the workers engaged in these precision and hazardous jobs, more emphasis should be given to psychiatric and neurological evaluation than to general and patternized physical checkup in certain aspects. In other words, it would be-ideal if we could screen out accident prone factors and risk factors related to neuropsychiatric disorders prior to military conscription or employment. Studies of this type, however, would incur a burden of huge expenses on the part of employers. The author has selected a certain number of youths and adults with normal findings of routine waking E.E.G. out of those who have had experiences of unconscious and/or convulsive spells, and thereby supplemented his previous preliminaty study entitled “I.M. Pentylenetetrazol Provocation E.E.G.”1977. In this study the author has been able to determine almost definitely the required amount of I.M. injection for the test, and carefully measured the “latency”up to the moment when paroxysms or positive responses are disclosed after an injection. The hours from and injection foreevery study until it is completed are really a breathless and extremely tense moment for the three physicians and technologists attending the test because of a possible drug induced “status”. The author has tried to figure out this latency in this study. The latency is meaningful in that it is the very “time lag”or “Induction Latency”spent for the pentylenetetrazol injection, and “ignition”to produce the burst of a big squib, namely a positive reponse on E.E.G. By knowing this lag, we would be able to use this procedure more easily and popularly.

瘦攀代理症性異常兒의 腦波所見例 14及6周波 陽性棘波複合體에 關하여

明好鎭 대한신경정신의학회 1963 신경정신의학 Vol.2 No.1

側頭葉滴疾의 腦波所見

明好鎭 대한신경정신의학회 1970 신경정신의학 Vol.9 No.1

痙攣代理病性異常兒의 腦波所見例 14及6周波 陽性棘波複合體에 關하여

明好鎭 大韓神經精神醫學會 1963 신경정신의학 Vol.2 No.1

「14 and 6」는 7년간이나 계속하여 한 환자의 뇌파에서 관찰된 예도 있으나 대개의 경우 2주내에 소실된다. 이 파형이 발작적인 도통, 복통 또는 행동이사, 자율신경장애(창백, 발한, nausea, vimitting, anorexia, 현기증, light-headedness, Temperature­alternation) 등과 병존하는 소아(15~16세)는 Epileptic­equivalent disorders로서 취급되어야 한다는 점을 염두에 두어야 하며, Dilantin, Phonobarbital 등은 증상의 현저한 개선을 보인다. 일부의 학자간에는 이 투약에 Diamox의 병용이 때로는 더 유효하다는 설도 있다. 이들 증례군의 약 30%에서 Head­injury 또는 cencephalitis의 병력을 지적발표된바 있었으니, 완전하 병인론적 고찰은 아직 이루어지지 못하였으며 이 이상복합체의 생성기전에 관하여도 별로 아는바 없어 학자간의 중요한 연구대상중의 하나라는 감이 있다.

韓國人의 腦波律動의 成熟過程 : 後頭部 正常律動의 成熟過程

明浩鎭 大韓神經精神醫學會 1976 신경정신의학 Vol.15 No.2

Among our sub-specialities the two figures of Lindsely and Gibbs are still often cited even though frequency analysis is partially computarized these days. For EEG trainess, they are good enough to tell at a glance electrographic maturation and organization, except changes of mean voltage with age. The two figures are: Gibbs' description dealing with the changes of fast wave and theta wave percentage time with age in his old atlas; and Lindsley's article entitled "A Longitudinal Study of the Occipital Alpha Rhythm." This is the second preliminary study of the electrographic maturation and organization with age in the EEG rhythms of Koreans, dealing particularly with mean frequency and mean amplitude of alpha wave (occipital dominant rhythm). EEG records and clinical data of 120 cases were analyzed. All of the cases had undergone EEG examinations for routine check at Seoul National University Hospital, EEG laboratory during the recent 9 years (1964-1972). Summary of the results: 1) The mean alpha frequency increased along with the age upto 13-15 age group, from which the normal adult pattern appeared, and decreased with the age starting from 46 until 60. 2) The frequency composition showed that 8 and 9 Hz were predominant in the ages upto 9 and after 9 years old, 10 Hz or more was dominant. Nine or slower cycles accounted for a third of the cases over 46 years old. 3) The mean alpha amplitude reached a peak at 7-9 age group and diminished with age thereafter.

폐쇄성 경동맥 질환에 있어 Doppler 초음파검사에 대한 연구

명호진,임병훈,이광우 대한신경과학회 1985 대한신경과학회지 Vol.3 No.2

韓國人의 腦波津動의 成熟過程Ⅲ : 開眼·閉眼이 後頭部津動에 미치는 影響 年齡別差異 THE RESPONSES TO THE EYE-OPENING AND CLOSURE ON THE OCCIPITAL DOMINANT RRYTHM ACCORDING TO THE AGE DIFFERENCE

明好鎭 大韓神經精神醫學會 1976 신경정신의학 Vol.15 No.4

"Clear blocking of alpha" can descern cortical blindness and simulated blindness on the spot, but this valuable finding is almost ignored in recent researches. This is the third preliminary study of electrographic maturation with age in the E.E.G. rhythms of Koreans, dealing particularly with the response to eye opening and eye closure. Electroencephalographic records and clinical data of 149 cases were analyzed. All of the cases had undergone electroencephalographic examinations for routine check at Seoul National University, Hospital, Electroencephalography Laboratory during the recent 9 years (1964-1972). The results are summerized as follows: (1) In the 4-6 age group blockings of occipital dominant rhythms were partial, incomplete or asymmetrical. (2) Starting from the age of 9, the blockings became nearly complete and symmetrical. (3) The above matured response continuted to the age of 46 at the shortest. (4) In this study, there was no "P-type" alpha.

側頭葉癎疾의 腦波所見

明好鎭 大韓神經精神醫學會 1970 신경정신의학 Vol.9 No.1

In temporal lobe epilepsy, forward migration of the focal epileptogenic discharges is, evident with the increase of the age. The discharges are localized in the posterior temporal region in the childhood, while those of the adult are between anterior temporal and mid-temporal region. In addition, some cases of the uncontrolled old temporal lobe epilepsy discloses significant mirror image formation of the spike discharges. This study comprises unexpectedly small number of classical centrencephalic epilepsies, which may be the result of negligence or disregard of proper medical examination and medical care. This is considered an important sociocultural problem, typical to a developing countries such as Korea.

癎疾의 腦波

明好鎭 대한의학협회 1979 대한의학협회지 Vol.22 No.9