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지갈탕(枳葛湯)이 C57BL/6형 생쥐의 알코올섭취량에 미치는 영향
변순임 ( Soon Im Byun ),김성곤 ( Sung Gon Kim ),김종우 ( Jong Woo Kim ),황의완 ( Wei Wan Whang ) 대한한방신경정신과학회 2007 동의신경정신과학회지 Vol.18 No.2
Objective : This study was designed to test the anti-craving effect of Gigaltang(extracts of Oriental medicinal herbs ; Hovenia dulcis and Puerariae flos) in C57BL/6 mice. Anti-craving effect was substituted by alcohol intake amount of C57BL/6 mice.Method : 60 C57BL/6 mice was randomized into vehicle(water) group and Gigaltang group. Only 39(vehicle group(21) and Gigaltang group(18)) was eligible for this study, and 21 C57BL/6 mice was dropped out. The procedure was composed of 5 days of adjustment period and 32 days of alcohol exposure and withdrawal period with limited access paradigm and 10 days of treatment period. Alcohol was offered only for 2 hours a day from 2 to 4PM and water was offered for 22 hours left. Food was offered for 24 hours a day. 1140mg/Kg/day of Gigaltang was administrated to 18 mice of Gigaltang group for 10 days whereas water to 21 mice of vehicle group. The amount of alcohol intake, water intake, food intake, body weight were measured every other day. Result : There weren`t significant differences in 2 hours of alcohol intake, 22 hours of water intake, 24 hours of food intake and body weight for ten days between Gigaltang and vehicle group. Conclusion : Anti-craving effect of Gigaltang on C57BL/6 mice wasn`t verified. To verify the anti-craving effect, further study with advanced animal model, various dose of Gigaltang and diverse period of drug administration should be taken.
한의학 정신요법 집단치료로 호전된 감별 불능 신체형장애 여환 1례
변순임 ( Soon Im Byun ),김상호 ( Sang Ho Kim ),박소정 ( So Jeong Park ),김지영 ( Ji Young Kim ),김종우 ( Jong Woo Kim ),정선용 ( Sun Yong Chung ),황의완 ( Wei Wan Hwang ),김지혁 ( Ji Hyouck Kim ) 대한한방신경정신과학회 2006 동의신경정신과학회지 Vol.17 No.3
Oriental Medicine Based Psychotherapy is consisted of 8 sessions which are available for various kinds of patients(mood disorders, somatoform disorders, anxiety disorders, Hwabyung, adjustment disorders etc.). Through 8 sessions, patients were educated on the relationship of mind and body which is the basic concept of oriental medicine and also received several training such as Progressive Muscle Relaxation, Autogenic Training, Breathing Training, Meditation, Qi-training. After these several training they get to think of their problems and inner conflict with people and get some insight about themselves and others, it can help handling their problems. This case report is about the patient with lots of somatic complains through the whole body, who got better after treatment by oriental medicine based psychotherapy added on herbal medicine and acupuncture.
정상인에서의 스트레스 반응 정도와 산화스트레스 사이의 상관관계 연구
변순임,김지영,조성훈,김종우,황의완,Byun, Soon-Im,Kim, Ji-Young,Cho, Seung-Hun,Kim, Jong-Woo,Hwang, Wei-Wan 대한예방한의학회 2009 대한예방한의학회지 Vol.13 No.2
Objective : This study was to examine a relationship among subjective psychological stress, physical stress response and oxidative stress. Methods : The subjects were consisted of 87 healthy volunteers. To assess subjective psychological stress, SRI(stress response inventory) was completed. To assess psychological and physical stress response, HRV(Heart Rate Variability) were tested. To assess oxidative stress, d-roms(Derivatives of reactive oxygen metabolites test) test was conducted. Subjects were divided into 3 groups depending on SRI(Stress Response Inventory) score, low stress response(LSR: lower than 30 percentile), Medium(MSR: 30-70 percentile) and high stress response(HSR: higher than 70 percentile). The Relationship between Stress Response and Oxidative Stress was estimated by correlation and One-way ANOVA analysis. Results : There were no significant differences of demographic data among 3 groups. There was a significant difference of oxidative stress among 3 groups. Conclusion : Our results suggest that there is a weak positive correlation between subjective psychological stress and oxidative stress. There is a significant difference of oxidative stress between HSR group and LSR group.
초기에 전환장애로 잘못 진단되었던 위증(위證)환자 보고 1례
김윤용 ( Yun Yong Kim ),변순임 ( Soon Im Byun ),김지영 ( Ji Young Kim ),황의완 ( Wei Wan Whang ),조성훈 ( Sung Hoon Cho ) 대한한방신경정신과학회 2007 동의신경정신과학회지 Vol.18 No.3
Conversion disorder is a diagnosis based on a psychological construct that currently has no known neurobiologic substrate. But It is not easy to differentiate a real conversion disorder from a neurological disease or other medical disease.A patient in this case report had been diagnosed as conversion disorder but later it was found that the conversion disorder was misdiagnosis. During the 7 days of treatment, this patient was treated by herb medication, acupuncture and TENS and had a little improvement. Both way, this patient was evaluated and evantually was diagnosed as Guillain-Barre Syndrome Miller-Fisher Variant, suggesting that the former diagnosis had been a mistake.In this case report, we will present this patient`s case and review the misdiagnosis of conversion disorder.
침구(鍼灸) 치료와 활락탕(活絡湯) 투여가 급성요통 및 간기능에 미치는 영향에 관한 임상적 고찰
임정은,송호섭,권순정,이성노,강미숙,변임정,황현서,김기현,Lim, Jeoung-Eun,Song, Ho-Sueb,Kwon, Soon-Jung,Lee, Seong-No,Kang, Mi-suk,Byun, Im-Jung,Hwang, Hyeon-Seo,Kim, Kee-Hyun 대한침구의학회 2001 대한침구의학회지 Vol.18 No.5
Objective : The purpose of this study was to investigate the effect of acupuncture, moxibustion and whuallak-tang on acute back pain and liver function. Methods : We investigated 34 acute back pain patients. We treated them with acupuncture, moxibustion and bed rest, herbal medicine (Whuallak-tang, Huoluo-tang, 活絡湯) and physical therapy and we observed clinical effects and checked the changes of AST,ALT,ALP on admission and 1week later. Results : The result obtained is as follows. The patients were 58.8% male and 41.2% female ranging in age from 29 to 76 years. after treatment, of the 34 cases, 10(29.4%) were obtained excellent results and 23(67.7%) were good, and 1(2.9%) case was obtained fair result, with the total effective rate being 97.1%. AST,ALT,ALP was within normal range on admission and 1week later. and AST and ALP were decreased but had no statically significance.(P>0.05) Conclusion : This study suggests that acupuncture, moxibustion and Whuallak-tang are effective on acute back pain and should not induce hepatotoxicity. even though there are few toxic herbs in Oriental medicine, acupuncture and general herbal medication by a oriental doctor should not injure liver function of human.
분노증세를 동반한 심인성 진전 환자에 대해 이완요법과 한방치료를 실시한 1례 보고
김상호 ( Sang Ho Kim ),박소정 ( So Jung Park ),변순임 ( Soon Im Byun ),김지영 ( Ji Young Kim ),김종우 ( Jong Woo Kim ),정선용 ( Sun Yong Chung ),황의완 ( Wei Wao Hwang ),김지혁 ( Ji Hyouck Kim ) 대한한방신경정신과학회 2006 동의신경정신과학회지 Vol.17 No.3
Psychogenic neurological conditions account for 1% to 9% of admissions at neurological unit. They are considered manifestations of underlying psychiatry disorders such as somatoform disorders and factitious disorders or malingering. Diagnosis for psychogenic tremor is difficult because mimic tremor is occurred at the secondary of the organic disorders or coexist in a patient with tremors of organic origin. A patient in this case report was diagnosed as psychogenic tremor, and she also complained the severe anger. A patient did not improved with the chemical medication for a long time. The patient received relaxation training, herbal medication and acupuncture for 20 days and showed short-term alleviation on tremor and decreased anger problem and other somatic problems.