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정상인의 팔걸이 사용에 따른 보행 시 하지 근 활성도의 변화
오규빈,손가을,김서연,김해든,백승민,송현수,윤상혁,조기훈,Oh, Gku Bin,Son, Ga Eul,Kim, Seo Yeon,Kim, Hae Deun,Back, Seung Min,Song, Hyen Su,Yun, Sang Hyeok,Cho, Ki Hun 대한물리치료과학회 2020 대한물리치료과학회지 Vol.27 No.3
Background: The purpose of this study was to investigate the change of lower limb muscle activation according to the use of arm sling in normal subjects. Design: Cross-sectional Study Methods: Seven healthy subjects (6 males and 1 female, 25.42 years, 173.57 cm, 71.71 kg) were recruited on a voluntary basis. To measure the lower limb muscle activation during walking with and without arm sling, we used a wireless surface electromyography (sEMG) (FreeEMG1000, BTS Bioengineering, Milano, Italy). Six wireless sEMG electrodes were attached to the following three major muscle groups of the both side lower limb: rectus femoris, biceps femoris, medial gastrocnemius. All subjects wore arm sling on their right side during measurement. Results: In the stance phase, there was a significant increase in right side rectus femoris muscle activation in walking without arm sling compared to the walking with arm sling (p<.05). Additionally, In the stance phase, there was a significant increase in left side tibialis anterior muscle activation in walking without arm sling compared to the walking with arm sling (p<.05). Conclusion: The results of this study suggest that there is a significant association between the arm swing restriction and lower limb muscle activation. Therefore, it seems that it can be applied as basic data for gait training with an arm slings.
마이크로플레이트를 이용한 8종 화학물질의 복귀돌연변이 평가
김명준 ( Myoung Jun Kim ),허성무 ( Seongmoo Heo ),남수현 ( Suhyun Nam ),백승민 ( Seng-min Back ),박성훈 ( Seong Hoon Park ),오정자 ( Jeong Ja Oh ),정영신 ( Young-shin Chung ) 한국동물실험대체법학회 2021 동물실험대체법학회지 Vol.15 No.1
This study was conducted to establish the technology for bacterial reverse mutation test using 384-well microplates and liquid media instead of solid agar in order to evaluate the mutagenicity of test articles with limited amounts. The important advantage of this test method was considered that the usage of S9 fraction prepared from rat liver was smaller in comparison with the Ames test using solid agar. Five bacterial strains (S. typhimurium TA98, TA100, TA1535, TA1537 and E. coli WP2 uvrA) recommended in OECD TG 471 were used to evaluate 8 chemicals including 6 mutagens (Allyl chloride, 4-amino-2-nitrophenol, ethylene glycol dimethyl ether, benzo[α]pyrene, 7,12-dimethylbenzanthracene, 8-hydroxyquinoline) and 2 non-mutagens (dioctyl phthalate, sulfisoxazole). All experiments were performed using Ames MPFTM Penta II kits (Xenometrix, Switzerland). Three independent laboratories participated in the intra-laboratory and inter-laboratory studies. Results from this study were compared with reference mutagenicity data (NTP or published data). In results of this study, five out of six mutagens were evaluated to be positive, and the one mutagen (ethylene glycol dimethyl ether) to be negative. Two non-mutagens were determined to be negative in microplate tests. Both the intra-laboratory and the inter-laboratory study showed the 87.5% concordance in the overall results. It was concluded that a microplated reverse mutation test may be a compatible test method for the animal welfare as well as for the limited amount of substances.
강승호(Seung ho Kang),천신(Shin Chun),김국한(Guk Han Kim),김경수(Kyoung soo Kim),백승민(Seung min Back),신재희(Jae hee Shin),조가은(Ga eun Jo),황민호(Min ho Hwang),최혁(Hyuk Choi) 대한전기학회 2014 대한전기학회 학술대회 논문집 Vol.2014 No.2
The pneumatic CPM (continuous passive motion) device was developed in our group. We mainly focused on fingers and wrists of patients. Rehabilitation devices require the highest standards due to the device directly interacts with patients. Using air pressure system, lightweight, compact, and cost effective CPM was designed and manufactured. We also human pilot clinical study was performed. The CPM would be utilized in hospital and at home as well.
생체 내 Pig-a 유전자 돌연변이시험에 대한 세 시험실의 전수가능성 평가
정영신 ( Young-shin Chung ),박범수 ( Bumsoo Pak ),한세희 ( Sehee Han ),이지연 ( Jiyeon Lee ),김지영 ( Jiyoung Kim ),백승민 ( Seng-min Back ),박초롱 ( Cho-rong Park ),김수환 ( Su-hwan Kim ),이종권 ( Jong-kwon Lee ) 한국동물실험대체법학회 2017 동물실험대체법학회지 Vol.11 No.1
In order to establish a pig-a gene mutation assay as a regulatory test for evaluating in vivo genotoxicity in Korea, the transferability study as a stage II validation was performed using the test substance, N-ethyl-N-nitrosourea (ENU) across three laboratories. The lead laboratory (KIT) standardized the protocol using Rat MutaFlow® Kit and transferred the methodology to two participating laboratories (Hoseo University and Biotoxtech Co. Ltd.). Sprague Dawley rats were treated with vehicle or three dose levels of ENU (10, 20, 40mg/kg) by oral gavages on the 3 consecutive days. On the day 15 after the first treatment, bloods were collected and analyzed to estimate the percentage of reticulocytes (%RETs), mutant type of RETs and erythrocytes (RBC) using flowcytometer. In results, the exposure of ENU induced the dose-dependent increases in the mutant frequencies of RBCCD59- and RETCD59-, while %RETs were not affected. Data comparisons among three participating laboratories indicated the good transferability with the high correlation coefficients (0.97-0.99) between the lead and participating laboratories. In conclusion, the pig-a gene mutation assay may be the effective test for the estimation of in vivo gene mutation and the validation studies may be needed using more test substances in Korea.
김현재,백승민 仁川敎育大學校 1990 論文集 Vol.24 No.2
Piaget had published "Experiments in contradiction" in 1974. He regarded resource of the contradiction as a representation of incomplete compensations between an Affirmation and a Negation in this book. And he classified this contradiction into three large groups, that is (1) contradictions between actions, (2) contradictions between subsystems, (3) contradictions from erroneous inferences. This study (I) is the first part; The Different forms of contradiction, in a series of research on "Experiments in contradiction". This study was composed of the piagetian cognitive contradiction theory and the content of the Experiments in contradiction and it`s analysis by the piagetian level.