다중 그룹 상황에서의 최소 효과 용량을 정하는 비모수적 검정법

배수현,김동재,Bae, Su-Hyun,Kim, Dong-Jae 한국통계학회 2012 Communications for statistical applications and me Vol.19 No.1

The primary interest of drug development studies is to estimate the smallest dose that shows a significant difference from the zero-dose control. The smallest dose is called the Minimum Effective dose(MED). In this paper, we suggest a nonparametric procedure to simultaneously find the MED of each group based on placements. The Monte Carlo simulation is adapted to estimate the power and the family-wise error rate(FWE) of the new procedures with those of discussed nonparametric tests to find MED. 신약 개발 연구 또는 임상시험에서 개발된 약이 0용량 대조군과 비교해 효과 차이가 있는 가장 작은 용량을 최소 효과 용량(MED)이라 한다. 본 논문에서는 다중 그룹 상황에서 동시적(simultaneous)으로 각 각 그룹의 최소 효과 용량을 확인하기 위하여 위치(placement)에 기초한 비모수적 방법을 제시하였다. 또한 Monte Carlo 모의실험을 통하여 기존에 제시된 검정법과 본 논문에서 제안한 검정법의 검정력(power)과 FWE(Family-wise Error Rate)를비교하였다.

한방병원 입원환자의 한.양방 약물 병용에 따른 간 기능 안전성 평가 : 전향적 관찰연구

배수현,박상은,강창완,홍상훈,Bae, Su-Hyun,Park, Sang-Eun,Kang, Chang-Wan,Hong, Sang-Hoon 대한한방내과학회 2013 大韓韓方內科學會誌 Vol.34 No.2

Objectives : To investigate the incidence of drug-induced liver injury (DILI) by combined-prescription of Korean herbal medicine (KHM; prescribed herbal medicine by doctors of traditional Korean medicine) and Western medicine on liver function. Methods : Sixty-nine in-patients who took KHM and Western medicine for various conditions were enrolled for prospective observational study. All subjects were given liver and renal function tests at the start of hospitalization to establish a baseline. After taking KHM and Western medicine, tests were done at approximately 4-week intervals afterwards. Results : Fifty-three subjects showed normal liver function test (LFT) at baseline, 50 subjects (72.5%) remained within the normal range at the second test, while 3 subjects (4.3%) tests revealed slight increase of LFT. However not a single patient had a high enough raised LFT to indicate liver injury. Sixteen of 69 subjects had abnormal baseline, 11 subjects recovered to normal levels and 5 subjects remained at abnormal level. Among all subjects, there was no statistically significant increase in LFT level between the first and second tests. Conclusions : This study shows that the combined-prescription of KHM and Western medicine did not cause any DILI. In some cases, combined treatment increased LFT levels but those increases were not high enough to have statistical significance. Additional large scale and systematical studies are required for more conclusive proof and results.

암 환자의 질병ㆍ치료관련 요인에 따른 불편감과 영적안녕에 관한 연구

배수현(Bae Su Hyun),박정숙(Park Jeong Sook) 기본간호학회 2007 기본간호학회지 Vol.14 No.4

Purpose: This study was done to analyze symptom distress and spiritual well-being in patients with cancer according cancer diagnosis, metastasis, treatment stage, number of hospitalizations and treatment modality. Method: The participants, 285 patients being treated in one of ten general hospitals either as in- or out-patients, completed the McCorkle and Young (1978) Symptom Distress Scale translated and adapted by Uhm (1986) and the Spiritual Well-Being Scale by Paloutzian and Ellison (1982) translated by Choi (1990). Data collection was done from June 19 to September 30, 2006. Results: For symptom distress, there were significant differences for cancer diagnosis (p=.018), metastasis (p=.000), treatment stage (p=.000), number of hospitalizations (p=.000), and treatment modality (p=.002). For spiritual well-being, the only significant difference was for cancer diagnosis (p=.002). Patients with ovarian/uterine cancer had the lowest spiritual well-being. Conclusion: For patients with cancer, symptom distress was significantly different for illness and treatment factors, in particular, stage of illness, while for spiritual well-being, patients with uterine ovarian cancer had the lowest spiritual level. These results indicate a need to develop nursing interventions to decrease symptom distress in patients according to treatment stage and to promote spiritual well-being, particularly in women with ovarian/uterine cancer.

헬리코박터 파일로리 감염의 한ㆍ양약 병용치료 효과 및 안전성에 관한 증례 보고

배수현(Su Hyun Bae),박선영(Seon Young Park),진명호(Myung Ho Jin),박상은(Sang Eun Park),홍상훈(Sang Hoon Hong) 한의병리학회 2012 동의생리병리학회지 Vol.26 No.3

중학생의 비자살적 자해에 영향을 미치는 요인 : 자해의 심각성을 중심으로

배수현(Bae, Su-Hyun),성희자(Sung, Hee-Ja) 한국정신건강사회복지학회 2020 정신보건과 사회사업 Vol.48 No.2

본 연구는 중학생의 비자살적 자해의 심각성(경도/중증도)에 따라 부모의 양육태도, 개인의 심리적 요인(충동성, 분노, 우울), 그리고 학교 환경적 요인인 학교 스트레스의 영향력이 다른지 살펴보았다. 이를 위하여 대구 소재의 중학교에 재학 중인 중학생 427명을 대상으로 설문조사를 실시하였다. 연구결과, 비자살적 자해의 경도 수준에는 우울, 분노, 부정적 양육태도가 유의미한 요인으로 나타났다. 중증도 수준에서는 우울만이 통계적으로 유의미하게 나타났다. 이러한 연구 결과를 바탕으로 몇 가지 제언을 제시하였다. 첫째, 자해의 심각성을 평가할 수 있는 평가지표를 개발하고 둘째, 부모교육을 통하여 자녀와의 의사소통을 원활히 하고 셋째, 청소년의 우울과 분노를 관리할 수 있는 상담프로그램과 전문가 연계를 제안하였다. This study examined whether the parents’ child-rearing attitude, individual psychological factors(impulsivity, anger, depression) and the influence of school stress factor are different from the severity(mild/severe) of non-suicidal self-injury of middle school students. For this purpose, the survey research was carried out for 427 middle school students attending middle school in Daegu Metropolitan City. The main findings of this study were as follows. First, depression, anger and parents’ negative rearing attitude were the significant factors in the mild-level of non-suicidal self-injury. Second, in the sever-level of non-suicidal self-injury only the depression was the statistically significant factor. Finally, the implications of this study findings are discussed.

수처리용 담체의 물리적 성상 분석(I) -공극률과 밀도-

배수현 ( Su-hyun Bae ),유찬서 ( Chan-seo You ),김영규 ( Young-kyu Kim ),정정조 ( Cheong-jo Cheong ),라덕관 ( Deog-gwan Ra ) 한국환경기술학회 2018 한국환경기술학회지 Vol.19 No.3

수계의 부영양화 원인물질인 질소, 인을 제거할 목적으로 수처리용 담체를 제조한 후, 물리적 특성에 대하여 검토한 결과는 다음과 같다. 담체의 공극률은 담체 제조 원료의 성상에 따라 다르게 나타났으며, 활성탄 담체 > 점토담체 > 제올라이트 담체 > 질석 담체 순으로 높게 나타났다. 활성탄 담체가 공극률이 가장 큰 이유는 소성과정에서 활성탄이 연소되어 공극을 형성하기 때문이다. 담체의 밀도는 소성온도가 높을수록, 점토의 함량이 많을수록 높게 나타났으며, 점토 담체 > 질석담체 > 제올라이트 담체 > 활성탄 담체 순으로 크게 나타났다. 점토 담체의 밀도가 가장 높은 이유는 소성온도가 높아질수록 담체가 유리화되고, 점토의 함량이 증가할수록 강도가 증가하기 때문이다. 담체의 압축강도는 소성온도가 증가함에 따라 증가하였으며, 점토 담체> 질석 담체> 활성탄 담체> 제올라이트 담체 순서로 높게 나타났다. 압축강도는 점토 함량이 많이 함유될수록 높게 나타났다. After the preparation of a water treatment media for the purpose of removing nitrogen and phosphorus which cause eutrophication of the water system, the physical properties were examined as follows. The porosity of the several media varied depending on the characteristics of the raw materials for the preparation of these, and was higher in the order of activated carbon media> clay media> zeolite media> vermiculite media. The reason why the activated carbon media had the largest porosity was because activated carbon were burnt to form pores in the calcination process. The densities of the media were higher as the calcination temperature was higher and as the content of clay was larger, and was the higher the order of clay media> vermiculite media> zeolite media> activated carbon media. The reason why the density of the clay media is highest is that the media is vitrified as the calcination temperature is higher, and the strength is increased as the clay content is increased. The compressive strength of each media was increased with increasing a calcination temperature and was higher in the order of clay media> vermiculite media> activated carbon media> zeolite material.

수처리용 담체의 물리적 성상 분석(II) : 질소와 인의 흡착효율

배수현 ( Su-hyun Bae ),유찬서 ( Chan-seo You ),김영규 ( Young-kyu Kim ),정정조 ( Cheong-jo Cheong ),라덕관 ( Deog-gwan Ra ) 한국환경기술학회 2018 한국환경기술학회지 Vol.19 No.4

수계의 조류발생 원인물질인 질소와 인을 제거할 목적으로 수처리용 담체를 제조한 후, 질소와 인의 흡착특성에 대하여 검토하였다. 담체의 질소, 인에 대한 흡착효율(평균값)은 평형흡착시간 24시간, 소성온도 700 ℃의 조건에서 점토 담체의 경우 19.7∼46.7(30.2) %와 16.4∼81.1(42.2) %, 제올라이트 담체의 경우 37.9∼91.5(67.8) %와 23.9∼49.0(31.7) %, 질석 담체의 경우 16.7∼50.8(31.4) %와 23.2∼71.0(42.6) %, 활성탄 담체의 경우 19.7∼54.1(34.5) %와 18.9∼72.4(40.8) %로 나타났다. 담체의 질소, 인에 대한 흡착특성은 Freudlich 흡착등온식으로 표현이 가능하였고, 흡착효율은 소성온도가 증가함에 따라 감소하는 경향을 나타냈다. 담체의 질소에 대한 흡착효율은 제올라이트 담체 > 활성탄 담체 > 질석 담체 > 점토 담체 순으로 높게 나타났다. 제올라이트 담체가 질소의 흡착효율이 높은 이유는 NH₄⁺-N 에 대한 양이온 교환능력이 크기 때문이다. 인의 흡착효율은 질석 담체 > 점토 담체 > 활성탄 담체 > 제올라이트 담체 순으로 크게 나타났다. A water treatment media was prepared for the purpose of removing nitrogen and phosphorus which cause the algae in the water system. The adsorption characteristics of nitrogen and phosphorus on the media were as follows. The adsorption efficiencies(average value) of nitrogen and phosphorus for the prepared media on the condition of 24 hours equilibrium adsorption time and 700 ℃ calcination temperature were measured as 19.7~46.7(30.2) % and 16.4~81.1(42.2) % on clay media, 37.9~91.5(67.8) % and 23.9∼49.0(31.7) % on zeolite media, 16.7∼50.8(31.4) % and 23.2∼71.0(42.6) % on vermiculite media, 19.7∼54.1(34.5) % and 18.9∼72.4(40.8)% on active carbon media, respectively. Adsorption characteristics of nitrogen and phosphorus for madia could be expressed by Freudlich ‘adsorption isotherm. The nitrogen and phosphorus adsorption efficiencies of each media showed a tendency to decrease with increasing calcination temperature. The adsorption efficiency of nitrogen was higher in order of zeolite media> activated carbon media> vermiculite media> clay media. The reason for the high nitrogen adsorption efficiency of the zeolite media was that the cation exchange capacity for NH₄⁺ -N was large. In addition, adsorption efficiency of phosphorus was increased in order of vermiculite media> clay media> activated carbon media> zeolite media.

간호대학생의 의사소통 능력과 리더십 향상을 위한 교과외 코칭프로그램 개발 및 효과검증

배수현(Bae, Su Hyun),박정숙(Park, Jeong Sook) 한국간호교육학회 2015 한국간호교육학회지 Vol.21 No.2

Purpose: The purpose of this study was to develop extracurricular coaching programs to improve communication skills and leadership for nursing students and evaluate the effects of the programs. Methods: The 8-week extracurricular coaching program was developed based on the Joo, Whitmore and Hong models. A quasi-experimental design was used. The subjects were selected by two full-time nursing professors training students at one university in city G. The subjects were chosen from among the advisees of these two professors. Of the students who participated in this study, 29 were in the experimental group and 27 were in the control group. Data was analyzed through t-test and Mann Whitney U-test. Results: The experimental group showed significantly higher post-test scores in communication skills, communication as a nursing outcome, observation of communication, leadership, and leadership as a nursing outcome than those of the control group. However, the experimental group did not reveal significantly higher post-test scores in the number of leadership activities using a portfolio than those of the control group. Conclusion: This extracurricular coaching program can help cultivate important, basic grounding as well as achieve nursing student learning outcomes upon graduation.

사회복지전공 대학원생들의 참만남 집단(Encounter Group) 경험에 대한 연구: 어려움과 대처를 중심으로

배수현(Bae, Su-hyun),성희자(Sung, Hee-ja),이유진(Lee, Yu-jin),김하은(Kim, Ha-eun) 한국사회복지교육협의회 2021 한국사회복지교육 Vol.54 No.-

본 연구는 사회복지전공 대학원생의 참만남 집단 참여 과정에서의 어려움과 대처 경험을 살펴보고자 하였다. 이를 위해 OO대학교 일반대학원 사회복지학부 내‘집단상담과 사회복지실천’수업시간에 진행된 참만남 집단 참여자 10명을 대상으로 설문조사 및 심층 인터뷰를 진행하였으며, 일반적 질적 연구 방법을 적용하여 자료를 분석하였다. 분석 결과, 참여자가 경험한 집단상담에서의 어려움은 <개인 내적 차원의 어려움>, <집단구성원과 상호작용 과정에서의 어려움>, <집단특성에 기인한 어려움>이라는 3개의 상위주제와 8개의 하위주제가 도출되었다. 참여자가 경험한 집단상담에서의 대처는 <적극적 대처>와 <소극적 대처>라는 2개의 상위주제와 7개의 하위주제가 도출되었다. 본 연구는 사회복지전공의 집단상담 참여자들의 어려움과 대처 경험을 통해 집단상담의 실제를 파악하였다는 점에서 의의가 있으며, 사회복지 교육 내 상담교육 활성화를 위한 기초자료가 될 수 있을 것이다. Observed the difficulties and coping experiences of graduate students majoring in Social Welfare participate in ‘Encounter Group’. The survey and interviews were performed with 10 participants of the ‘Encounter Group during the Group Counseling and Social Welfare Practice class in the OO University s Graduate School. All data were retrieved using general qualitative research. The difficulties in group counseling experiences were divided into three high-level themes: ‘Difficulties at the individual level’, ‘Difficulties in the process of interaction with group members’, and ‘Difficulties due to group characteristics’ and eight sub-themes. Participant s coping experience in group counseling was divided into two high-level themes: ‘Active coping’ and ‘Passive coping’ and seven sub-themes. Result conveys the reality of group counseling through the difficulties and coping experiences from the participants, and could be used as a basis for revitalizing counseling education in Social Welfare study.

간호대학생의 간호학 학습성과 성취도와 중요도 인식

배수현(Bae, Su Hyun),박정숙(Park, Jeong Sook) 한국간호교육학회 2013 한국간호교육학회지 Vol.19 No.1

Purpose: The purpose of this study was to examine the recognition of achievement and importance of nursing program outcome among nursing students. Methods: The survey was performed with 439 nursing student and recruited from 3-year or 4-year nursing students, scheduled to graduate from university. The data was collected by questionnaires and was analyzed with SPSS statistics 19.0. Results: The achievement of nursing program outcome was 3.28. and the important of that was 4.38. The achievement of nursing program outcome on critical thinking and communication of 4-year nursing students were higher than 3-year nursing students. Achievement of program outcome were significantly different according to satisfaction of curriculum, club activity and voluntary activity. Conclusion: These findings indicate that outcome-based nursing curriculum is need to consider the importance and achievement level of program outcome for nursing students.