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      • 항암제 유발 말초신경병증 한의 치험 2례

        홍상훈,정유진,Hong, Sang Hoon,Jung, Yu-jin 대한암한의학회 2019 大韓癌韓醫學會誌 Vol.24 No.2

        Objective : Peripheral neuropathy refers to the symptoms caused by damage to peripheral fibers, inflammation and degeneration. This study reports the effects of moxibustion, electric moxibustion, and pharmacopuncture including GeonChil(Rhus verniciflua stokes, 乾漆)and Whalhyul(活血) pharmacopuncture on patients with peripheral neuropathy induced by anti-cancer drugs and chemotherapy. Method : We administered moxibustion, electric moxibustion, GeonChil and Whalhyul pharmacopuncture to two patients who showed peripheral neuropathy induced by anti-cancer drugs and chemotherapy. The symtoms were evaluated using Visual Analog Scale (VAS) and chemotherapy induced peripheral neuropathy assessment tool (CIPNAT). Results : Following observations were made after treatments. Case 1 : After nine procedures, the score of VAS was decreased. Feeling of cold and numbness were improved, and as rotation movement of ankle was also possible, gait disturbance were improved. Case 2 : After, seven procedures symptoms of both shoulder pain were improved, and the symptoms of peripheral neuropathy were eliminated. Conclusion : We found the possibility of symptom improvement after moxibustion, electric moxibustion, and pharmacopuncture treatment on peripheral neuropathy caused by anti-cancer drugs. Clinical studies of pilot study and control settings will need to be carried out later.

      • KCI등재

        장회소설(章回小說)의 새로운 독법(讀法)을 위하여 ―≪유림외사(儒林外史)≫를 중심으로

        홍상훈 한국중국어문학회 2007 中國文學 Vol.53 No.-

        到了≪儒林外史≫問世, 從“四大奇書”開始的中國古代文人敍事轉入到新局面了。 吳敬梓把章回小說和史傳、 筆記、 類書等的傳統敍事樣式集成到這部巨作, 而創新了一個可謂“獨門絶招”的敍事模式。 因此, ≪儒林外史≫成爲了一部又有意思又有意味的, 而且需要文人靜思閱讀的敍事巨作。吳敬梓通觀兩千年“士林”歷史和淸代士紳社會的細情, 而看破了積年層累的制度矛盾所産生的知性落墮落和處在?死的士文化現局。 他看來, 喪失傳統原本之社會使命感却有?自在的淸代士人集團早已變成爲一群“多余”的、 无所用的“社會病根”了。 所以他解剖了這個无望的士人社會, 而抽出了種種典型的“病根標本”――這些標本, 那可以歸納于四大門類: 八股士、 假名士、 賢人、 奇人。 然后他通過文學的形象化工程來“加工”這些標本, 而把?在精心計劃的“自然史博物館”――≪儒林外史≫里展示了。而且, 在這一部連綴“?談”的敍事巨作里, 他對于那些漂泊于“道義”與“勢利”之間, 因而銷盡心靈、 无奈衰落的“士而非士、 儒而非儒”的“多余人群”, 一面暴露他們的丑惡而反諷, 又一面表示同情。 耐人尋味, 吳敬梓自己也通過化爲一個故事人物(杜儀)而成爲一種暴露和反諷 、 同情的對象。 結果, ≪儒林外史≫別有成就了敍事模式上又創新又高雅的一個水平: 在形式方面?近于“說部”, 而在實質上已遠于現成的“說部”――因爲那里面的“話法”和“文法”比較文人化了; 在“作意”方面?近于“史傳”, 而在實質上逈異于現成的“史傳”――因爲那里面的故事大多屬于?章回小說一樣的虛構故事。 所以, 吳敬梓只得給他命了別個新名字――“外史”。

      • Monitoring of the earth using space-based observations

        홍상훈 한국항공우주학회 2012 한국항공우주학회 학술발표회 논문집 Vol.2012 No.11

        인공위성으로부터 관측된 원격탐사 위성정보는 지구 관측을 위한 다양한 분야에서 널리 활용되고 있다. 주 활용분야는 지도제작, 안보 감시, 자연재해 감시, 기상, 지질, 해양 등이다. 인간의 눈과 유사한 가시광선 영역 이외에 적외선, 마이크로파 대역의 전자기파를 이용한 원격탐사 정보는 지구에 대한 보다 잘 이해하는데 도움을 준다. 한국항공우주연구원은 인공위성 연구개발뿐만 아니라 위성정보로부터 얻을 수 있는 다양한 이차 정보 등을 해석 연구하고 있으며, 이 논문에서는 다양한 지구관측 위성자료 활용 현황에 대해 알아볼 것이다. Space-based observations have been widely used to monitor earth surfaces for several application areas such as cartography, security & surveillance, natural disaster monitoring, weather, geology, oceanography, agriculture, environmental monitoring, etc. Satellite information with different orbit configuration and various electromagnetic spectrum like infrared, microwave, etc, can be useful to understand earth’s surface. Korea Aerospace Research Institute (KARI) is playing a key role in the satellite as a hub of the nation’s space development. KARI has developed and launched successfully a series of KOMPSAT (Korea Multi-Purpose Satellite). In this paper, the status of application using earth observation satellite will be reviewed.

      • KCI등재

        재생불량성빈혈(再生不良性貧血)의 변증론치(辨證論治)에 대(對)한 고찰(考察)

        홍상훈,이승연,Hong Sang-Hoon,Lee Seung-Yeon 대한한방소아과학회 1999 대한한방소아과학회지 Vol.13 No.2

        Background/Aims: Aplastic anemia is defined as pancytopenia (anaemia, leucopenia, and thrombocytopenia) result from aplasia of the bone marrow. Many studies have shown that survival rate of aplastic anemia is 50-60% with immunomodulation therapy. In Korea, there is a lack of research considering oriental herbal medicine with aplastic anemia. Methods: It was compared and analyzed that recently several experimental or clinical reports of oriental herbal medicine on aplastic anemia. Results and Conclusion: The oriental herb of Panax ginseng radix, Cprdonopsis pilosula radix, Astragalus membranaceus radix, Atractylodes marcrocephala. Cervi Cornu Parvum, Epimedii Herba, Boshniakiae Herba, Morindae Radix, Angelicae gigantis Radix, Cascutae Semen, Lycii Fructus, Polygoni Multiflori Radix potently stimulated hematopoietic stem cell activity, Response rate to oriental herbal medicine of aplastic anemia was 30-60% and effect rate of aplastic anemia was 73-93%, Bian zheng Lun zhi(辨證論治 treatment according to syndrome differentiation) which based on Shen xu(腎虛) is presumed to approach highest degree effect in response rate.

      • KCI등재

        과음하는 성인남자 53 명의 음주패턴과 간 장애에 대한 분석 연구

        홍상훈,조정효,손창규,Hong, Sang-Hun,Cho, Jung-Hyo,Son, Chang-Gue 대한한방내과학회 2007 大韓韓方內科學會誌 Vol.28 No.1

        Objectives : To investigate the correlations among alcohol consumption, alcoholic liver disorders, physical symptoms, and behaviors in heavy drinkers. Methods : 53 males who self-realized their severe alcohol consumption were enrolled in this study. 10 answers for a questionnaire, serum parameter, sonographic finding and body mass index were attained. The correlations between them were analyzed using Pearson's correlation and Student's t-test. Results : The average consumption of alcohol in these subjects was 2.5-fold over social drinkers. The incidence of alcoholic hepatitis was around 30%, while fatty liver 73%, and abnormal GGT 77%, respectively. No specific correlation between average volume of daily alcoholic consumption and alcohol-related hepatic parameters was shown in this study, but correlative tendency between fatty liver and body mass index was exhibited. Conclusions : This study may indicate that alcoholic liver injuries are caused by not just volume of alcohol consumed but more mixed factors including inherited genetic components, body fat mass, foods and other physical or emotional stress.

      • KCI등재

        알코올 섭취량에 따른 한의변증설문(DSOM)의 타당성에 대한 연구

        홍상훈,김정은,김성환,박상은,수현,강창완,이인선,Hong, Sang-Hoon,Kim, Jung-Eun,Kim, Sung-Hwan,Park, Sang-Eun,Hong, Su-Hvun,Kang, Chang-Wan,Lee, In-Sun 대한한방내과학회 2009 大韓韓方內科學會誌 Vol.30 No.1

        Purpose : This study was conducted to find the possibility of DSOM (Diagnosis System of Oriental Medicine) as a diagnostic method according to alcohol intake. Method : 49 men who drink alcohol over 40g per day and whose AUDIT scores were over 12 were allocated to the drinker group. 30 men who do not drink alcohol at all were allocated to the control (non-drinker) group. The study period was from June 15, 2006 to September 30, 2008. All of both groups were analyzed using DSOM. Result : There were some differences between the drinker group and the non-drinker group in stagnation of Ki(氣滯), deficiency of Yin(陰虛), insufficiency of Yang(陽虛), heat syndrome(熱), dryness (燥), and lung(肺). A group whose gamma-GTP is over twice the normal condition shows meaningful difference in stagnation of Ki(氣滯), heat syndrome(熱), dryness(燥), and insufficiency of Yang(陽虛). Conclusion : We found out that DSOM can be a diagnostic method on alcoholic liver disease patients. However, other studies to supplement it should be continued.

      • KCI우수등재

        신체 및 건강 정보를 이용한 회귀분석기반 헤모글로빈 추정에 관한 연구

        홍상훈,광석 대한전자공학회 2021 전자공학회논문지 Vol.58 No.9

        본 논문에서는 건강검진 빅데이터에 포함된 신체(키, 몸무게 및 허리둘레) 및 건강 정보(이완기 혈압, 트라이글리세라이드 및 혈청지오티(ALT) 등)를 이용하여 회귀분석을 기반으로 하는 헤모글로빈 추정 방법을 제안하고자 한다. 선행 연구를 통해 신체 및 건강 정보를 이용한 헤모글로빈 추정 가능성은 확인하였으나, 해당 연구는 테스트데이터를 통한 검증을 수행하지 않고 훈련데이터를 이용하여 모델을 생성 및 평가하였으며, 독립변수 조합이 1개 또는 7개라는 점 등의 한계를 지닌다. 상기 문제점을 보완하기 위하여 본 논문에서는 총 4,026,293명의 신체 및 건강 정보가 포함된 건강검진 빅데이터를 이용하여 헤모글로빈과의 상관성을 통계적으로 분석하였으며, 전체 인원 및 특징(성별, 연령대 및 흡연상태)에 따른 세분화 클래스에 대해 선형 및 다중 회귀분석을 수행하여 헤모글로빈을 추정하였다. 또한, 2~7개의 독립변수를 이용한 다중 회귀분석을 수행하고 결과를 비교하였다. 실험 결과, 3개의 특징(성별, 연령대 및 흡연상태)으로 세분화된 클래스에 대해 선형 및 다중 회귀분석을 수행하였을 때 각각 6.149%, 6.010%로 가장 낮은 평균 오차율이 계산되었다. In this paper, we propose a regression analysis based hemoglobin estimation method using body (height, weight, and waist circumference) and health information (diastolic blood pressure, triglyceride and ALT(SGPT), etc.) included in health examination big data. Prior studies have confirmed the possibility of estimating hemoglobin using physical and health information, but it has limitations such as the model was created and evaluated using train data without verification through test data, and used 1 or 7 combinations of independent variables. In this paper, to compensate for the above problems, statistically analyzed the correlation with hemoglobin using big data of medical examinations containing a total of 4,026,293 physical and health information. and Linear and multiple regression analyses were performed to estimate hemoglobin for segmentation classes based on the total number of people and features (gender, age group and smoking state). Furthermore, multiple regression analyses using two to seven independent variables were performed and the results were compared. Experiments show that the lowest error rate was calculated at 6.149% and 6.010%, respectively, when linear and multiple regression analyses were performed for classes subdivided into three features (gender, age group and smoking state).

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