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- 저자 : 배락천 ( Rack Cheon Bae ) (검색결과 4 건)
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증례 : 소화기 ; 간내 결석에 동반된 담관 방선균증 1예
배락천 ( Rack Cheon Bae ),정민규 ( Min Kyu Jung ),조한진 ( Han Jin Cho ),박수영 ( Soo Young Park ),조창민 ( Chang Min Cho ),탁원영 ( Won Young Tak ),권영오 ( Young Oh Kweon ) 대한내과학회 2009 대한내과학회지 Vol.77 No.3
방선균증은 만성 화농성 육아종성질환으로 임상증상 및 영상학적 소견이 비특이적이어서 진단에 어려움이 있는 질환이다. 저자 등은 임상적으로 방선균증을 의심하지 않았던 50세 여자 환자에서 총담관 결석 및 간내 결석에 동반되어 간절제수술 후 조직학적으로 확인된 방선균증을 경험하였기에 문헌고찰과 함께 보고하는 바이다. Actinomycosis is a chronic, suppurative, granulomatous disease caused by Actinomyces species, a filamentous, Gram-positive anaerobic bacterium and a normal inhabitant of the oral cavity and gastrointestinal tract characterized by sulfur granule formation. Primary bile duct actinomycosis is very rare in Korea and the pathogenesis of this infection is poorly understood. We report a case of actinomycosis of the intrahepatic bile duct, concomitant with common bile duct and intrahepatic duct stones presenting as intermittent right upper quadrant abdominal pain without fever as the chief complaint in a 50-year-old woman. The radiologic findings revealed multiple intrahepatic duct and common bile duct stones. On performing a left lobectomy of the liver and endoscopic retrograde cholangiopancreatography, marked dilatation of the intrahepatic bile duct and many brown pigment stones in the intrahepatic duct and common bile duct were observed. Primary bile duct actinomycosis was confirmed by identifying sulfur granules with neutrophilic infiltration in the intrahepatic duct. (Korean J Med 77:343-348, 2009)
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연구논문 : 만성 간질환 환자에서 순간탄성측정법(transient elastography, Fibroscan(R))에 의한 간탄력도에 영향을 줄 수 있는 임상요소
배락천 ( Rack Cheon Bae ),조한진 ( Han Jin Cho ),오종택 ( Jong Taek Oh ),이응갑 ( Eung Kap Lee ),허준 ( Jun Heo ),신근영 ( Keun Young Shin ),박수영 ( Soo Young Park ),정민규 ( Min Kyu Jeong ),전성우 ( Seong Woo Jeon ),조창민 ( Ch 대한간학회 2010 Clinical and Molecular Hepatology(대한간학회지) Vol.16 No.2
Background/Aims: Transient elastography as performed using the Fibroscan? is a useful noninvasive method for evaluating hepatic fibrosis. However, recent studies have found that liver stiffness measurement (lSM) values are inappropriately elevated in acute hepatitis or in the acute flare state of chronic hepatitis, suggesting that the lSM value obtained by the Fibroscan? is not a reliable marker for fibrosis. We retrospectively evaluated the clinical factors influencing the lSM value obtained using transient elastography as performed using the Fibroscan? in patients with chronic liver disease. Methods: A total of 298 patients who were followed in Kungpook National University Hospital from November 2007 to May 2008 due to previously established liver cirrhosis or chronic liver disease were investigated using the Fibroscan?, laboratory test, ultrasound, and/or abdominal computed tomography. Results: The 298 patients were aged 47.8±12.9 years (mean±SD). The cut-off value for a diagnosis of liver cirrhosis was 12.5 kPa (as used in previous studies). Thirty-six patients (15%) and 202 patients (85%) with chronic liver disease without clinical manifestation of cirrhosis had lSMs of >12.5 kPa and <12.5 kPa, respectively. Multivariate analysis revealed that lSM values were unusually increased in patients with chronic liver disease who were older (P=0.007) or who had increased gamma gultamyltranspetidase (GGT) (P=0.022), decreased albumin (P=0.015), or increased total bilirubin (P=0.009). Conclusions: This study reveals that age, GGT, and albumin are clinical factors influencing lSM values. This reinforces the need to interpret lSM values in the context of a defined diagnosis, biochemical data, radiologic examination, and other clinical findings.
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증례 : 소화기 ; 식용 숯으로 인한 말단 회장에 발생한 탄분 침착증
배문섭 ( Mun Seop Bae ),배락천 ( Rack Cheon Bae ),신무철 ( Moo Cheol Shin ),박경현 ( Kyung Hyun Park ),조승제 ( Seoung Jae Cho ) 대한내과학회 2009 대한내과학회지 Vol.76 No.4
Anthracosis is a very common disease of the bronchus, while anthracosis of the gastrointestinal tract is extremely rare. Only a few cases of anthracosis of the esophagus have been reported and no cases of anthracosis of the terminal ileum are known, except one patient in Korea who was described as having melanosis ilei. A black pigmented lesion was detected in the terminal ileum on colonoscopic examination of a 51-year-old woman. Histological examination revealed a pigmented lesion beneath the mucosal epithelial layer and lymphoid follicular hyperplasia. The lesion consisted of an aggregation of histiocytes containing abundant tiny black pigments. She has taken oral charcoal for 7 years. We diagnosed anthracosis of the terminal ileum caused by oral charcoal and report a case of charcoal-induced anthracosis of the terminal ileum. (Korean J Med 76:490-493, 2009)
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소화기 ; 대구, 경북 지역 Helicobacter pylori 일차 및 이차 치료의 연도별 제균율 변화: 최근 9년 성적
조한진 ( Han Jin Cho ),배락천 ( Rack Cheon Bae ),이순학 ( Soon Hak Lee ),장선익 ( Sun Ik Jang ),이현석 ( Hyun Seok Lee ),최소영 ( So Young Choi ),신근영 ( Keun Young Shin ),허준 ( Jun Heo ),김성국 ( Sung Kook Kim ),정민규 ( Min K 대한내과학회 2009 대한내과학회지 Vol.76 No.2
목적: 최근 H. pylori의 항생제 내성률이 증가하고 있으나, 각 지역별로 H. pylori 일차 삼제요법에 의한 제균율의 변화추세에 대한 연구가 부족한 실정이다. 이번 연구에서 대구 경북지역의 단일기관의 최근 9년간 H. pylori 제균율의 변화추세를 조사하였다. 방법: 1999년 1월부터 2007년 12월까지 H. pylori 양성으로 진단받고 일주일간 일차 제균 요법을 시행한 615명의 환자의 제균율을 연도, 궤양 위치에 따라 후향적으로 조사하였다. 결과: 전체 환자의 H. pylori 제균율은 81.6%였다. 궤양 위치와 PPI의 종류에 따른 제균율의 차이는 없었다. Per-protocol 분석에 의한 연도별 제균율은 1999, 2000, 2001, 2002, 2003, 2004, 2005, 2006, 2007년에 각각 76.3%, 78.3%, 82.8%, 88.5%, 77.8%, 91.7%, 84.8%, 75.4%, 83.7%였다. 최근 9년간 제균율의 차이는 없었다(p=0.760). 결론: 대구 경북지역에서 일차 제균 치료로서 PPI를 기본으로 하는 삼제 병합요법은 최근 9년 동안 제균율 변화 경향을 보이지 않아 아직까지 유용한 치료법으로 생각되나, 절대적인 치료효과가 낮아 향후 새로운 치료법을 찾기 위한 더 많은 연구가 필요할 것으로 생각한다. Background/Aims: The reported prevalence of antibiotic resistance in Helicobacter pylori infection has been increasing. However, recent trends in the eradication rates of H. pylori using first-line triple regimens are rarely reported. Therefore, we determined the trend in the H. pylori eradication rates in a single center for the most recent 9 years in Daegu and Kyungpook provinces, Korea. Methods: From January 1999 through December 2007, the eradication rates in 615 H. pylori-positive patients who received one-week triple regimens were evaluated retrospectively according to year and ulcer location. Results: The overall H. pylori eradication rate was 81.6%. The eradication rate from the years 1999 to 2007 was 76.3, 78.3, 82.8, 88.5, 77.8, 91.7, 84.8, 75.4, and 83.7%, respectively, based on the per-protocol analysis. No definite evidence of a decreasing tendency of the eradication rate was seen over the 9 years (p=0.760). Furthermore, there was no significant difference in the eradication rate according to ulcer location. Conclusions: There is no decreasing trend in the H. pylori eradication rate over the past 9 years in Daegu and Kyungpook provinces. However, the eradication rates are not satisfactory, and further investigation is needed to develop more effective regimens.
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