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해표양진탕(解表兩陳湯) 및 해표이진탕(解表二陳湯)이 Guinea Pig의 기관지(氣管支) 평활근(平滑筋)에 미치는 영향(影響)
박천수,한상환,Park, Cheon-Su,Han, Sang-Hwan 대한한방내과학회 1990 大韓韓方內科學會誌 Vol.11 No.2
This study was carried out to investigate the effect of Heapyoyangjintang and Haepyoejintang extract on the contractile force of the isolated guinea pig trachea smooth muscle and elucidate its mechanism. The results were obtained as follows : 1. The isolated trachea smooth muscle was suspended in the organ bath with oxygenated kreb's Henseleit bicarbonate buffer solution at $37^{\circ}C$, and the developed tension by the drug was recorded with Isometric transducer(nacro F-60). The resting tension was approximately 0.5g. 2. The trachea smooth muscle of the isolated guinea pig was significantly relaxed by the administration of Haepyoyangjintang and Haepyoejintang extract. 3. The contractile response of the trachea smooth muscle of the isolated guinea pig to histamine$10^4M$ Was significantly inhibited by Heapyoyangjintang and Haepyoejintang extract. 4. The contractile response of the trachea smooth muscle of the isolated guinea pig to acetylcholine$10^4M$ was considerably inhibited by Haepyoyangjintang and Haepyoejintang extract. 5. The contractile response of the trachea smooth muscle of the isolated guinea pig to 5-hydorxytrtrypptamine $10^4M$ was considerably inhibited by Haepyoyangjintang and haepyoejintang extract.
정천탕(定喘湯)의 효능(效能)에 관한 실험적(實驗的) 연구(硏究)
박천수,한상환,Park, Cheon-Su,Han, Sang-Whan 대한한방내과학회 1996 大韓韓方內科學會誌 Vol.17 No.1
These studies were carried out to investigate the effect of Jungchuntang water extract on the inhibitory contractile action of acetylcholine in rat. The results of these studies were as follows; 1. Contractile force of acetylcholine from trachea smooth muscle in rat was significantly inhibited by Jungchuntang. 2. Dose-response of acetylcholine pretreated Jungchuntang in rat was not significantly changed. 3. Inhibitory contractile action of acetylcholine pretreated propranolol in rat was decreased. 4. Inhibitory contractile action of acetylcholine pretreated indomethacin was not significantly changed by Jungchuntang. 5. Inhibitory contractile action of acetylcholine pretreated methylene blue was significantly changed by Jungchuntang. 6. Contractile force of acetylcholine from trachea smooth muscle in rat was significantly inhibited by Jungchuntang. 7. Dose-response of acetylcholine pretreated Jungchuntang in rat was not significantly changed. 8. Inhibitory contractile action of acetylcholine pretreated propranolol in rat was decreased. 9. Inhibitory contractile action of acetylcholine pretreated indomethacin was not significantly changed by Jungchuntang. 10. Inhibitory contractile action of acetylcholine pretreated methylene blue was significantly changed by Jungchuntang.
복령보심탕(茯笭補心湯)이 해수(咳嗽)에 미치는 임상적(臨床的) 고찰(考察)
박천수,이시형,Park, Cheon-Su,Lee, Si-Hyeong 대한한방내과학회 2000 大韓韓方內科學會誌 Vol.21 No.2
Objective : To observe the effect of Bokryungbosim-tang on the cough, cough patients medicine Bokryungbosim-tang. Methods : A clinical observation was done on 30 case of cough patients, treated by Bokryungbosim-tang, who were hospitalized frome January, 1. 1999 to December, 31, 1999 at the department of IKSAN Oriental Medicine Hospital, Wonkwang University and Pak Cheon Soo oriental medical clinic. Results : The effect of treated by Bokryungbosim-tang is that excellent was 19 case(63.33%), good 3 case(10%), fair 3 case(10%) and poor 5 case(16.66%). Conclusions : These results indicate that the effect of Bokryungbosim-tang on the cough is excellent.
위식도접합부 선암에서 근위부 절제연의 길이가 예후에 미치는 영향
박천수 ( Cheon Soo Park ),김태환 ( Tae Hwan Kim ),김범수 ( Beom Su Kim ),김갑중 ( Kab Choong Kim ),오성태 ( Sung Tae Oh ),김병식 ( Byung Sik Kim ),육정환 ( Jeong Hwan Yook ) 대한임상종양학회 2010 Korean Journal of Clinical Oncology Vol.6 No.1
목적 : 위식도접합부 선암의 수술적 치료시 근위부 절제연의 길이가 환자의 예후에 미치는 영향을 알기 위해 연구 하였다. 대상 및 방법 : 2001년 1월 1일부터 2003년 12월 31일 까지 서울아산병원 외과에서 위식도접합부 선암으로 수술을 시행 받은289명 환자의 의무기록을 후향적으로 분석하였다. 환자를 T 병기(AJCC, 6th,2001)에 따라 T1 이하인 군(T1, n=66) 과 T2이상인군 (T2-4, n=223)으로 나누어 각군에서 생존율에 영향을 미치는 근위부 절제연의 길이를 분석하였다. 결과 : 위식도접합부 선암으로 수술 받은 289명의 환자중T1(n=66)에서는 근위부 절제연의 길이가 예후에 영향을 미치지 않았다. T2-4(n=223)에서는 병리학적 표본에서 근위부 절제연의 길이가 0.5 cm 이하인 경우만 통계적으로 의미 있는 것으로 보였다. (p=0.009) 결론 : 위식도접합부 선암에서 조기 위암은 근위부 절제연의 길이가 예후에 영향을 미치지 않았으나 진행성 위암에서는 병리학적 표본에서 근위부 절제연의 길이를 최소한 0.5 cm이상 확보하는 것이 필요하다. Purpose: To determine the length of proximal resection margin for patients with adenocarcinoma of the gastroesophageal junction(GEJ). Materials and Methods: We reviewed retrospectively the medical records of the 289 patients who underwent surgery for adenocarcinoma of GEJ in our institution between Janury 2001 and December 2003. Result: The 289 patients who underwent surgery for adenocarcinoma of GEJ were divided on T stage, below T1 group(T1,n=66) and above T2 group(T2-4, n=223). We studied the influence of proximal resection margin in adenocarcinoma of the GEJ on survival. In T1(n=66) group, univariate analysis revealed no influence of proximal resection margin in adenocarcinoma of GEJ on survival. In T2-4(n=223) group, univariate analysis revealed influence of proximal resection margin on survival ; 0.5cm, 2.0cm, 3.0cm, 3.5cm, 4.0cm. Multivariate analysis show that only influence of proximal resection margin on survival; 0.5cm (p=0.009, HR:2.232, 95% CI:1.218-4.091) Conclusion: We should be undergoing surgery for T2-4 gastric adenocarcinoma of GEJ with safely proximal resection margin; >0.5cm for survival improvement.
밀폐된 원통내부에서 회전체의 형상이 회전유동에 미치는 영향에 관한 실험적 연구
김유곤,박천수,Kim, Yu-Gon,Park, Cheon-Su 대한기계학회 2002 大韓機械學會論文集B Vol.26 No.5
Two-dimensional, angle-resolved LDV(Laser Doppler Velocimetry) measurements of the turbulent rotating flow field in a confined cylinder have been performed. The configurations of interest are flows between a rotating upper disk with a rod attached by a disk or impeller($\theta$ = 45$^{\circ}$, 90$^{\circ}$) and a stationary lower disk in a confined cylinder. The mean flow velocity as well as the turbulent intensity of the flow field have been measured. The results show that the flow is strongly dependent on the position of the impellers or the disk, negligibly affected by the Reynolds number in turbulent flow. It is observed that the mixing effect of the axial flow impeller($\theta$ = 45$^{\circ}$) is better than that of the radial flow impeller($\theta$ = 90$^{\circ}$) or a disk.