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프로필티오유라실 (Propylthiouracil)과 연관된 p-ANCA 양성 혈관염에 동반된 초점성 분절성 사구체 경화증
박윤경 ( Yoon Kyung Park ),윤여욱 ( Yeo Wook Yun ),성상석 ( Sang Suk Sung ),박의순 ( Ui Soon Park ),박성현 ( Sung Hyun Park ),우진현 ( Jin Hyun Woo ),박재일 ( Jae Il Park ),장선주 ( Sun Joo Jang ),한상웅 ( Sang Woong Han ),오영하 대한신장학회 2004 Kidney Research and Clinical Practice Vol.23 No.6
왕준광 ( Joon Kwang Wang ),박의순 ( Ui Soon Park ),이혜순 ( Hye Soon Lee ),엄완식 ( Wan Sik Uhm ),김태환 ( Tae Hwan Kim ),배상철 ( Sang Cheol Bae ),유대현 ( Dae Hyun Yoo ),안유헌 ( You Hern Ahn ),최윤영 ( Yun Young Choi ),주경빈 ( 대한류마티스학회 2004 대한류마티스학회지 Vol.11 No.4
Objective: Decrease in bone mineral density (BMD) occurs relatively early and is known to be correlated with disease activity in patients with ankylosing spondylitis (AS). We investigated BMD and its correlation factors in Korean patients with AS. Methods: Fifty patients with AS fulfilling modified New York criteria and age-, sex-, and body mass index-matched 100 normal controls were selected. Medical records were reviewed retrospectively. Lumbar and femur BMD was measured using a dual energy X-ray absorptiometry. Results: Both lumbar and femur BMD in patients with AS were significantly lower than BMD in control group. Although Bath ankylosing spondylitis disease activity index, C-reactive protein and erythrocyte sedimentation rate showed no correlation with BMD, lumbar BMD in patients with high disease activity in terms of inflammatory factors was significantly lower than that in patients with low disease activity. Conclusion: BMD in patients with AS was significantly lower than those in control group. Early detection and appropriate management will be necessary in patients with AS.