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      • KCI등재SCOPUS
      • KCI등재SCOPUS
      • KCI등재

        고환염전에 의한 세포고사에서 세포고사 억제인자인 Clusterin의 변화 및 역할에 관한 연구

        박은찬,곽철,손환철,오승준,이상은,최황 대한비뇨의학회 2004 Investigative and Clinical Urology Vol.45 No.4

        Purpose: This study examined the histological changes and apoptosis in contralateral rat testes after testicular torsion or the repair of torsion, and investigated the functional role of clusterin in the pathogenesis for the injury of the contralateral testes after testicular torsion. Materials and Methods: H&E staining and TUNEL assay were performed in contralateral testes following torsion or repair of torsion. The mean numbers of spermatids per tubule and apoptotic germ cells per tubule were calculated in each group with respect to time. The expression of clusterin after torsion or the repair of torsion was observed by RT-PCR and Western blot analysis. Results: Following the repair of torsion, significant germ cell injuries and abnormal spermatogenesis were observed in the contralateral testes compared to those without repair. The expressions of clusterin mRNA and protein after testicular torsion were no different from those in the control testes. However, in the contralateral testes, the clusterin mRNA and clusterin protein expressions in the contralateral testes were increased 8 hours after the repair of torsion. The appearance of apoptosis in the contralateral testes after the repair of torsion appeared to correlate with the clusterin protein expression. Conclusions: The injury to contralateral testes during testicular torsion seems to be caused by the apoptosis induced by reperfusion of ischemic torsioned testis. Clusterin appears to play an antiapoptotic role in the apoptotic process in the injury to the contralateral testis due to the repair of testicular torsion. (Korean J Urol 2004;45:380-389)

      • KCI등재SCOPUS
      • KCI등재

        경쟁기반 이기종 무선 통신망의 공존 성능 분석

        박은찬 ( Eun-chan Park ),임민중 ( Minjoong Rim ) 한국인터넷정보학회 2011 인터넷정보학회논문지 Vol.12 No.4

        본 논문은 전송 전력과 전송 범위가 서로 다른 이기종 무선 통신망이 경쟁 기반의 채널 접속 프로토콜을 사용하여 공존하는 경우 채널 공유의 형평성과 효율에 관해 분석한다. 먼저, 기존에 널리 사용되는 경쟁 기반의 채널 접속 메커니즘인 CSMA(Carrier Sensing Multiple Access) 프로토콜을 사용하여 채널을 공유하는 경우, 이기종 시스템간의 반송파 감지의 비대칭성과 간섭으로 인한 전송실패를 인지하지 못하는 이진 지수 백오프 메커니즘과 링크 적응 메커니즘에 의해 채널이 불공평하게 공유됨을 밝힌다. 다음으로, 공간 재사용성과 공평한 채널 공유를 동시에 보장할 수 있는 반송파 감지 문턱값의 조건을 유도하고, 통신망의 처리율에 관한 수학적인 모형을 수립하여 경쟁 윈도우와 전송 속도가 채널 공유의 형평성과 효율에 끼치는 영향을 분석한다. 마지막으로, 다양한 환경에서의 모의 실험을 수행하여 공평한 채널 공유를 위한 여러 가지 접근 방법의 채널공유 성능을 비교한다. This paper analyzes the fairness and efficiency of channel sharing when heterogeneous wireless networks that have different transmission power and/or coverage coexist with the contention-based channel access protocol. First, we show that the existing CSMA (carrier sensing multiple access) protocol, that is a prevailing contention-based mechanism, results in significant unfairness of channel access because of (1) the asymmetric capability of carrier sensing and (2) the blindness of binary exponential backoff and link adaptation mechanisms to the interference-driven transmission failures. Next, we derive the feasible region of carrier sensing thresholds that assures spatial reuse and fair channel sharing simultaneously. Moreover, we establish an analytical model for per-system throughput and investigate the effect of contention window size and transmission rate on the fairness and efficiency of channel sharing. Finally, we compare the performance of several approaches for fair channel sharing via simulations under various network configurations.

      • KCI등재

        일제강점기 미션스쿨 계성학교의 운영에 대한 학생들의 비판적 인식과 활동

        박은찬 ( Park Eun-chan ) 역사교육학회 2018 역사교육논집 Vol.66 No.-

        This study looked into the students’ critical perception and activities in the operation of mission schools during the Japanese occupation period based on the examination of Keisung School. Students from Keisung School led the March First Independence Movement of Daegu and continued the anti-Japanese movement afterwards. In addition, they opposed the missionaries’ school operation policy through the movement to weed out the teaching staff on the missionary’s side, and actively developed the movement to raise their school to the status of a designated school through allied strikes; finally, making their school one of the few designated schools in the nation. Recent studies on mission schools have paid attention to students rather than the missionaries themselves. This study also examined students and their activities in connection with specific incidents and subsequent situations comprehensively. Particularly, it examined in detail, articles from the Dong-A Ilbo, the Chosun Ilbo and other newspapers published at that time, investigating their allied strikes and the movement to weed out teaching staff, which have not been covered profoundly in the Centennial History of Keisung and other studies. To begin with, this study examined the missionaries’ selection of miscellaneous schools as a result of the Revised Private School Norms and the effect of the March First Independence Movement on the students’ perception of the present situations and their organized activities afterwards. Starting from the independence movement, their critical perception became clear and their conscious resistance became more organized. This served as a driving force that led students from Keisung School to resist the Japanese through the movement to close up stores and the Hyeseongdan Group. Their conscious resistance continued into allied strikes. They expressed their willingness through allied strikes, and went on strike for the improvement of lessons, the replacement of equipment and the weeding out of teaching staff. The movement to weed out the teaching staff resulted from the students’ resistance against the missionaries’ arbitrary operation of not only Keisung School but also the entire religious circles of Daegu. As a result of the movement, several teachers left school, and in the process, the students experienced fierce friction with the school because of their allied strikes. The March First Independence Movement led the Japanese to change its colonial policy from military colonial rule to cultural colonial rule. As a result of this, the system of designated schools was introduced. This system had the contradiction of causing imbalance between miscellaneous schools. Most mission schools of the North Presbyterian Church did not pay much attention to the system of designated schools. Henderson, the principal of Keisung School, said that Keisung School’s primary goal was to propagate religion and its secondary goal was education. He would maintain its status of a miscellaneous school. As those who graduated from miscellaneous schools were not allowed to enter advanced schools, the students officially began the movement to elevate their school to the status of a designated school even before the introduction of the designated school system. That is, their aspiration for high school was expressed in their allied strikes. In the course of the strikes, they were collectively expelled from school, and the school’s alumni and their parents also participated in the movement. Finally, thanks to their frequent allied strikes, their school was raised to the status of a designated school. The students of Keisung School expressed their demands regarding the operation of the school in direct actions. They resisted against the Japanese as seen from the March First Independence Movement and the Hyeseongdan Group. Furthermore, they endeavored to make their demands reflected in the operation of the school, which included the weeding out of the teaching staff and raising their school to the status of a designated school through allied strikes. All this indicates that they actively participated in the operation of the school with the perception that they are the subjects of education.

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