전침 및 봉약침치료를 시술한 양성전립선비대증 환자의 임상증상개선에 대한 후향적 단면연구

박성환,한수련,강지석,안영민,안세영,이혜정,이병철,Park, Sung-Hwan,Han, Su-Ryun,Kang, Ji-Suck,Ahn, Young-Min,Ahn, Se-Young,Lee, Hye-Jung,Lee, Byung-Cheol 대한한방내과학회 2010 大韓韓方內科學會誌 Vol.31 No.3

Obejectives : To investigate the clinical effect of electroacupuncture and bee venom acupuncture for benign prostatic hyperplasia(BPH) symptoms. Methods : Among 39 outpatients who were treated at a BPH clinic, 8 were finally selected for analysis by charts-review, retrospectively. They were treated by electroacupuncture and bee venom acupuncture more than 3 times. We estimated the effectiveness of the treatments by using the International Prostate Symptom Score (IPSS) questionnaire and checking their nocturia frequency. On the basis of these variables, we analyzed the statistical significations of symptom improvements. Results : Among 8 patients, the IPSS and nocturia frequency showed significant improvement after the final treatment compared with baseline (P = .0078, P = .0078). The IPSS significantly decreased even after the 1st treatment and also after the 2nd treatment compared with the baseline (P = .0078, P = .0078). The IPSS at post final-treatment, post 1st- and post 2nd treatment also showed significant improvement compared with IPSS at baseline in 6 severe symptomatic patients(P = .031, P = .031, P = .031). Nocturia frequency decreased after the 1st treatment compared with baseline and showed significant improvement between baseline and post 2nd treatment (P = .0078). Conclusions : In a retrospective and cross-sectional study investigating the clinical effects of electroacupuncture and bee venom acupuncture on BPH, these treatments proved to have significant therapeutic effects, particularly for various symptoms involving frequent nocturia.

협업설계를 위한 엔지니어링 프레임워크 개발에 관한 연구 -자동차 서스펜션 모듈에의 적용-

박성환,이재경,이한민,Park, Seong-Whan,Lee, Jai-Kyung,Lee, Han-Min 한국전산구조공학회 2008 한국전산구조공학회논문집 Vol.21 No.6

This paper describes an e-Engineering framework to support collaborative design of automotive suspension systems developed at KIMM(Korea Institute of Machinery and Materials). The e-Engineering framework is proposed and developed on the base of the multi-layered software agents including engineering task agent which is generated from the domain knowledge of experts. The developed framework is aim to widely spread application to the small and medium enterprises by adopting open source technologies such as JADE (Java Agent Development Framework) and by using the independent characteristics related with applicant H/W and 81W system. This framework can provide an integrated design environment to support distributed personnel, design activities and engineering resources during product development process. For the validation of the system's applicability and efficiency, the several practical design processes for automotive suspension systems of RR/FR lower arms and RR cross member are applied and discussed. 본 논문에서는 한국기계연구원에서 개발된 자동차 서스펜션을 대상으로 한 협업설계 지원 엔지니어링 프레임워크 개발에 관하여 기술한다. 개발된 엔지니어링 프레임워크는 각 분야별 전문가 지식에 기초한 엔지니어링 task agent를 포함한 다양한 복수 계층의 소프트웨어 에이전트로 구성된다. 본 프레임워크는 폭 넓은 국내 중소제조기업 적용 확산을 목적으로 JADE(Java Agent Development Framework)와 같은 공개 소스 프로그램 기반으로 개발하였으며, 프레임워크의 확장성을 유지하기 위하여 관련 H/W 및 응용 S/W의 독립성을 가능한 한 유지하도록 노력하였다. 개발된 프레임워크는 제품개발과 정에 있어 지역적으로 분산된 사용자 및 엔지니어링 자원 등을 효과적으로 활용할 수 있는 통합된 협업 설계환경을 제공한다. RR/FR lower arm 및 RR cross member와 같은 몇 개의 실제 자동차 서스펜션 모듈의 설계엔지니어링 문제에의 적용을 통하여 본 시스템의 적용성과 효율성을 확인하였다.

EHA의 특징 및 활용분야

박성환,Park, S.H. 유공압건설기계학회 2009 드라이브·컨트롤 Vol.9 No.2

류마티스 관절염의 예방과 관리

박성환,Park, Seong-Hwan 한국건강관리협회 2004 한국건강관리협회지 Vol.2 No.2

Rheumatoid arthritis(RA) is the most common inflammatory joint disease and a major cause of disability, morbidity, and mortality. It occurs worldwide, affecting approximately one percent of adults. Inflammation of the synovial membrane surrounding a joint leads to swollen, tender, and stiff joints RA has no known cure and the diagnosis is made based on clinical criteria and many different options exist for treatment. All of these factors magnify the importance of the patient-physician interaction and place a premium on the art rather than the science of medicine. The major goals of therapy for RA are to relive pain, swelling, and fatigue; improve joint function; stop joint daage, and prevent disability and disease-related morbidity. Some combination of nonsteroidal anti-inflammatory drugs(NSAIDs), steroids, and DMARDs is necessary in almost patients. In many combinations of different DMARDs or DMARDs plus biologicals are necessary for optimal control. Additionaly, all patients with RA should be educated about their disease and the therapies that will be used. Patient education is essentially early in the disease course and on going basis Much research is focused on the further development of biological agent for treatment of RA. Elucidation of the trigger or trigers for RA may allow us to begin to think about prevention of RA.

저온 스트레스에 발현이 유도되는 콩의 L-asparaginase 유전자의 분리

박성환,김기영,진량,이재헌,Park, Seong-Whan,Kim, Kee-Young,Chen, Liang,Lee, Jai-Heon 한국식물생명공학회 2002 식물생명공학회지 Vol.29 No.2

Suppression subtractive hybridization (SSH)를 통해 저온에 의해 발현이 유도되는 cDNA들을 분리하였고, 그 중 하나인 slti182는 asparaginase 유전자들과 높은 유사성을 보였다. Slti182의 전체 cDNA인 GmASP1은 1258 bp 길이에 326개 아미노산으로 구성된 긴 Open reading frame (ORF)를 포함하고 있었다. GmASP1 단백질은 애기장대의 putative asparaginase (AB012247)와 84%의 유사성을 보였으나, 애기장대의 다른 isoform(Z34884)와는 55%의 유사성을 나타내었다. GmASP1 유전자는 저온 처리 후 3시간째부터 발현이 유도되어 6시간째에 최대발현을 나타내었고, 이후 점차 감소하여 48시간에는 저온처리전 수준으로 되돌아왔다. 또한, 식물체를 저온에서 48시간 둔 후에 다시 상온으로 옮겼을 때, 정상수준으로 떨어진 GmASP1의 발현이 다시 증가하는 양상을 보였다. 이러한 결과로 볼 때, GmASP1이 저온 스트레스에 반응 초기의 단백질 합성 촉진에 중요한 역할을 할 것으로 사료된다. Suppression subtractive hybridization (SSH) was used to isolate wound-induced cDNAs from wounded soybean. One of low-temperature-inducible cDNA, slti182 showed high homology with genes encoding 1-asparaginase. The full length cDNA of slti182, deginated GmASP1, is 1258 bp long and contains an open reading frame consisted of 326 amino acids. CmASP1 protein showed the highest identity (84%) with putative asparaginase from A. thaliana (AB012247), but it showed only 55% identity with another isoform of A. tathaliana (Z34884). The expression of GmASP1 during low temperature stress started to increase 3 hours after treatment, reached the maximum at 6 hour, and then decreased to the initial level at 48 hours. The amount of GmASP1 transcripts increased again when low-temperature-treated plants were transferred to room temperature, The present study suggests that GmASP1 may function to accelerate the protein synthesis which is important in the early response to low temperature.

정보보안문화와 경영진 리더십이 조직 구성원의 정보보안 행동에 미치는 영향

박성환,김범수,박재영,Park, Sunghwan,Kim, Beomsoo,Park, Jaeyoung 한국정보보호학회 2022 정보보호학회논문지 Vol.32 No.2

This research investigates the impacts of information security (IS) culture and management leadership styles on employee's security behaviors (IS policies compliance, IS participation) in financial institutions. This study use the survey data collected from 236 employees of financial institutions. This research shows that IS culture has a positive effect on both behavioral intentions to comply with IS policies and the intentions to actively participate in information security activities. Transactional leadership has a positive impact on the IS policies compliance intentions and to participate in information security activities. In contrast, transformational leadership has a positive impact on the intentions to participate in information security activities, but not on the IS policies compliance intentions.

재발성 음경지속발기증 1례

박성환,백선호,한수련,안영민,안세영,이병철,Park, Sung-Hwan,Paik, Sun-Ho,Han, Su-Ryun,Ahn, Young-Min,Ahn, Se-Young,Lee, Byung-Cheol 대한한방내과학회 2011 大韓韓方內科學會誌 Vol.32 No.1

Priapism is a persistent penile erection that continues for more than 4 hours beyond, or is unrelated to, sexual stimulation. Because priapism is a medical emergency, all patients with priapism should be evaluated and treated urgently. Subtypes of priapism are ischemic, non-ischemic and stuttering priapism. Stuttering type is a recurrent form of ischemic priapism in which unwanted painful erections occur repeatedly with intervening periods of detumescence. The etiology of this type is often idiopathic and the treatments are still not clearly established. We present one case of stuttering priapism which occurred after suppression of his sexual desire. A 23-year-old man visited our clinic complaining of recurrent pain and erections persisting for about 5 weeks. We performed evaluation and confirmed the diagnosis of Rigid swollen penis. Jibaekjihwang-tang gamibang (ZhiBaiDihuang-Tang Jiaweifang) was administerd to the patient for 9 days. After the treatment, duration of erections and pain showed remarkable improvements. This will be recorded as the first case report of treating priapism with a Korean medical approach and suggests that Korean medicine therapy can be efficient to treat priapism.

사회학의 '베버 르네상스' 오려는가

박성환,Park, Seong-Hwan 대한출판문화협회 1992 출판저널 Vol.106 No.-

베버에 있어서는 모든 것을 이해한다는 것이 모든 것을 용납한다는 것을 뜻하지 않았다. 그는 근대적인 서구문화의 유산과 토대 위에서 비서구적.비근대적 문화를 이론적.실천적으로 극복하여 서구문화의 장래를 보다 확고한 기반위에 올려놓으려고 했다.

학령전 아동을 대상으로한 유치열기 치주조직의 임상적 연구

박성환,김성조,최점일,Park, S.H.,Kim, Seong-Jo,Choe, Jeom-Il 대한치주과학회 1992 Journal of Periodontal & Implant Science Vol.22 No.2

한국에서의 시보업무 고찰

박성환,Park, Seong-Hwan 한국과학기술단체총연합회 1976 과학과 기술 Vol.9 No.9

시간은 일상 생활에서 중요한 비중을 차지하고 있다. 천문관측을 기초로하여 시민 생활과 항해항공에 필요한 표준시간의 유지관리 및 경위도를관측하는 시보업무는 천문대에서 중요한 비중을 차지하며 일상 생활과 밀접한 관례가 있다.