http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
박상희,염정록,장일무,Park, Sang-Hi,Youm, Jeong-Rok,Chang, Il-Moo 한국생약학회 1991 생약학회지 Vol.22 No.2
In the preceding paper, it was reported that total 63 traditional Korean herbal medicines listed in the Korean Pharmacopoeia and Korean Natural Drug Standards were found to be different plants in terms of systematic botany when those were compared with other two countries' drug compendia, Chinese Pharmacopoeia, Japanese Pharmacopoeia and Japanese Natural Drug Standards. Among 63 traditional Korean herbal drugs, 28 items were subject to the chemical identification test by using official methods that are described in the Korean Pharmacopoeia and the Korean Natural Drug Standards. In addition, 5 items were also tested by using the official methods described in Chinese and Japanese drug compendia, since there are no official chemical tests available in the Korean drug compendia. It was found that most of chemical tests appeared to be suitable. It was noted that the chemical test for Atractylodis Rhizoma(蒼朮) was incorrect and unapplicable. Those chemical tests for Clematidis Radix(威靈仙), Rubi Fructus(覆盆子) and Viticis Fructus(蔓荊子) are desirable to be revised for more accurate identification.
한 · 중 · 일의 공정서(약전 및 규격집)에 수재된 전통천연약물의 품질에 관한 조사(Ⅱ). : 대한약전 및 대한약전외 한약 (생약) 규격집의 확인시험법에 대한 검토
박상희(Sang Hi Park),염정록(Jeong Rok Youm),장일무(Il-Moo Chang) 한국생약학회 1991 생약학회지 Vol.22 No.2
In the preceding paper, it was reported that total 63 traditional Korean herbal medicines listed in the Korean Pharmacopoeia and Korean Natural Drug Standards were found to be different plants in terms of systematic botany when those were compared with other two countries` drug compendia, Chinese Pharmacopoeia, Japanese Pharmacopoeia and Japanese Natural Drug Standards. Among 63 traditional Korean herbal drugs, 28 items were subject to the chemical identification test by using official methods that are described in the Korean Phamarcopoeia and the Korean Natural Drug Standards. In addition, 5 items were also tested by using the official methods described in Chinese and Japanese drug compendia, since there are no official chemical tests available in the Korean drug compendia. It was found that most of chemical tests appeared to be suitable. It was noted that the chemical test for Atractylodis Rhizoma(蒼朮) was incorrect and unapplicable. Those chemical tests for Clematidis Radix(威靈仙), Rubi Fructus(覆盆子) and Viticis Fructus(蔓荊子) are desirable to be revised for more accurate identification.
한 · 중 · 일의 공정서(약전 및 규격집)에 수재된 전통천연약물의 품질에 관한 조사 (Ⅰ) : 기원에 관한 분류학적 검토
박상희(Sang Hi Park),염정록(Jeong Rok Youm),장일무(Il-Moo Chang) 한국생약학회 1991 생약학회지 Vol.22 No.2
Traditional drugs (herbal and animal drugs) of Korea, China and Japan have developed essentially from the same origin, since the traditional medicine of three countries has been originated from ancient China. Due to different geographical locations and discrepancy of plant resources of the traditional drugs, some divergency in terms of systematic botany in traditional drug materials has appeared in the three countries. Present report aims to survey traditional herbal drugs that have been called same traditional names in three countries, but they are actually different with respect to systematic botanical view-point. The official drug compendia(pharmacopoeia and natural drug standards) of three countries were subject to examination. Survey was conducted by the following categories. Traditional drugs were listed under same name, however, 1) they belong to different genus; 7 traditional herbal drugs were listed. 2) they belong to same genus, but different species; 24 traditional herbal drugs were found. 3) a variety of related species are used; 15 traditional drugs were listed. 4) actually same plant, but taxonomical name is differently called and/or different parts of plant are used; 10 traditional drugs were counted. 5) animal drugs belong to one of the above categories; 7 traditional animal drugs were found. Total 63 traditional drugs(herbal and animal) were found to comprise different taxonomical names when the official drug compendia of Korea, China and Japan were examined.
Propofol 정주 통증에 대한 서로 다른 두 농도의 Remifentanil 전처치 효과
탁양주 ( Yang Ju Tak ),박상희 ( Sang Hi Park ),김상태 ( Sang Tae Kim ) 대한마취과학회 2009 Korean Journal of Anesthesiology Vol.57 No.2
Background: Propofol produces anesthesia with rapid recovery but also causes pain on injection. This study was designed to evaluate the effects of two different concentrations of remifentanil for minimizing the pain caused by propofol and to compare the hemodynamic changes during propofol-remifentanil infusion. Methods: In a randomized, double-blind study of 80 patients, we compared the severity of the injection pain of propofol between two groups of patients. The initial effect-site target concentration of remifentanil was set at 4 ng/ml (the R4 group, n=40) or 8 ng/ml (the R8 group, n=40). After the effect-site concentration of remifentanil was achieved, the infusion of propofol was started with the concentration of 4 μg/ml. The remifentanil-related complications were evaluated and the severity of the pain caused by propofol was compared by using a four-point scale during the propofol infusion. The heart rate and arterial blood pressure were measured at pre-induction, just before intubation and at 1 minute after intubation. Results: The severity of injection pain of propofol was significantly lower in the R8 group than in the R4. There was no significant difference in the incidence of remifentanil-related complications between the two groups. Compared with the pre-induction values, the heart rate and arterial blood pressure were significantly lower at pre-intubation and at 1 minute after intubation in the R4 and R8 groups. Conclusions: Pretreatment with an effect-site concentration of 8 ng/ml remifentanil may be useful for minimizing the propofol injection pain compared with 4 ng/ml remifentanil. (Korean J Anesthesiol 2009;57:155∼60)
Magnesium sulfate가 저산소 상태에서 세포영양막의 Caspase-3와 Caspase-9의 발현에 미치는 영향
이귀세라 ( Gui Se Ra Lee ),김사진 ( Sa Jin Kim ),허민 ( Min Hur ),박상희 ( Sang Hi Park ),이희진 ( Hee Jin Lee ),이원선 ( Weon Sun Lee ),신종철 ( Jong Chul Shin ) 대한산부인과학회 2003 Obstetrics & Gynecology Science Vol.46 No.3
목적 : 저산소 조건에서 Magnesium sulfate (MgSO4)가 세포영양막 (cytotrophoblast)의 apoptosis에 미치는 영향을 알아보고자 하였다. 연구 방법 : 임신 2기의 태반으로부터 세포영양막을 분리하여 정상 조건 (20% O2)과 저산소 조건 (1-2% O2)에서 여러 생리적 농도 (0, 4, 8, 12 mM)의 MgSO4를 첨가하여 12시간과 36시간 배양한 후 apoptosis 정도를 평가하기 위하여 TUNEL 염색과 Objective : To determine the effect of magnesium sulfate (MgSO4) on the expression of caspase-3 and caspase-9 of cytotrophoblasts in vitro under normal and hypoxic condition as assessed immunoblot analyses. Methods : Normal cytotrophoblasts were isolated
황산마그네슘이 인간제대정맥내피세포의 VEGF와 Caspase-3에 미치는 영향
이귀세라 ( Gui Se Ra Lee ),김사진 ( Sa Jin Kim ),김소영 ( So Young Kim ),이영 ( Young Lee ),박상희 ( Sang Hi Park ),신종철 ( Jong Chul Shin ),유영옥 ( Young Oak Lew ),김수평 ( Soo Pyung Kim ) 대한주산의학회 2004 大韓周産醫學會雜誌 Vol.15 No.3
목적 : 황산마그네슘이 혈관 내피 세포의 caspase-3와 VEGF의 농도에 어떠한 영향을 미치는지를 알아보기 위하여 본 연구를 하였다. 방법 : 임신 말기에 계획된 제왕절개를 시행한 태아의 제대로부터 정맥내피세포(HUVECs)를 추출하여 TNF-α로 처리한 군과 처리하지 않은 두 군으로 나누어 황산마그네슘을 각 농도 별(0, 4, 8, 12 mM)로 가하여 배양한 후 배양 상청액으로 VEGF에 대한 ELISA assay를, caspase-3에 대하여 colorimeter assay를 시행하여 그 농도를 측정하였다. 결과 : HUVECs에서의 VEGF의 발현 농도는 TNF-α로 처리한 경우가 처리하지 않은 경우에 비하여 유의적으로 증가하였다. TNF-α를 가한 경우는 황산마그네슘의 농도에 따른 VEGF의 농도에 유의적인 차이가 없으나 TNF-α를 가하지 않은 경우 황산마그네슘의 농도가 4 mM 및 8 mM인 경우에 가장 낮은 농도로 발현되었다. caspase-3의 농도는 TNF-α와 황산마그네슘의 농도에 따른 유의적인 차이가 없었다. 결론 : HUVECs에서의 VEGF의 발현은 TNF-α에 의하여 증가되나 황산마그네슘의 농도 변화에 따른 영향은 없고, TNF-α에 의한 자극이 없는 경우는 황산마그네슘의 치료적 농도에서 그 발현은 감소되는 반면 caspase-3의 발현은 TNF-α와 황산마그네슘의 영향을 받지 않는 것 같다. Objectives : To determine the effects of magnesium sulfate on Caspase-3 and Vascular endothelial growth factor (VEGF) of human umbilical vein endothelial cells (HUVECs) under presence or absence of Tumor necrosis factor (TNF-α). Methods : HUVECs were isolated from normal term umbilical cords and cultured in several physiolo-gically relevant concentrations of magnesium sulfate with or without exposure of TNF-α. The concentrations of VEGF and caspase-3 were estimated by colorimetric assay and ELISA assay, respectively. Results : The concentration of VEGF in HUVECs significantly increased in the presence of TNF-α compared with in the absence of TNF-α. However, the concentration of VEGF did not show significant difference in several concentrations of magnesium sulfate concentrations with addition of TNF-α and it showed the lowest concentration under 4 mM and 8 mM of magnesium sulfate concentration without addition of TNF-α. The concentration of caspase-3 in HUVECs did not show statistically significant difference with the addition of TNF-α and magnesium sulfate. Conclusion: TNF-α induce HUVECs to stimulate the VEGF, and magnesium sulfate might not have the effects on the expression of VEGF with addition of TNF-α. However, the concentration for treatment of magnesium sulfate inhibits the expression of VEGF without addition of TNF-α. Magnesium sulfate might not have an effect of the expression of caspase-3 with or without addition of TNF-α.
성선 자극 호르몬과 사이토카인이 인간 황체 세포의 아포프토시스에 미치는 영향
김민정 ( Min Joung Kim ),허수영 ( Soo Young Hur ),유영옥 ( Young Oak Lew ),권동진 ( Dong Jin Kwon ),김장흡 ( Jang Heub Kim ),이진우 ( Jin Woo Lee ),이원선 ( Weon Sun Lee ),박상희 ( Sang Hi Park ),김은중 ( Eun Jung Kim ) 대한산부인과학회 2003 Obstetrics & Gynecology Science Vol.46 No.3
목적 : 초기 황체기 동안에 성선 자극호르몬 (gonadotropin)과 사이토카인 (cytokine)이 황체 세포의 아포프토시스 (apoptosis)에 미치는 영향과 아포프토시스 관련 인자인 Fas, Fas-L, Bcl-2, Bax, p53과 caspase-8의 발현 변화 및 상호 관련성을 조사하여 황체의 성장과 퇴화에 관여하는 기전의 단서를 알아내고자 하였다. 연구 방법 : 황체 세포를 배양액만으로 24시간 배양한 것을 대조군으로 하였고, 다양한 농 Objective : Our object is to evaluate the detailed mechanisms of support and regression of the human corpus luteum. Methods : To investigate the regulation of luteal function by gonadotropins, cytokines, and prostaglandins, the frequency of apoptosis and
박상희,김홍범,허윤,김정근,태명산,양웅석 대한소화기내시경학회 1981 Clinical Endoscopy Vol.1 No.1
A clinieal Observation was done on the 110 cases (male; 52 cases, female; 58 cases) of duodenitis under the gastroduodenoscopic examination among the patients who were performed endoscopic examination because of seeking for the cause of dyspepsia period from Aug. 1981 to Sep. 1981 at Department of lnteral Medicine of BNUH. The results were summerized as follow 1) Normal finding(Grade 0) was highest as 40% in the incidence according to grade of duodenits. Next was moderate (Grade II & II) as 24. 5%, the 3rd was mild(Grade I ) as 20% and lowest in severe(Grade IV) duadenitis as 15.5%. 2) Sex distribution of duodenitis showed 37 cases in male and 29 cases in female. And male was slightly higher in incidence than female. 3) Age distribution of duodenitis revealeii 3rd decade and 4th decade were highest in incidence, 30 cases and 28 cases respectively. The order of frequency was 5th decade, 6th decade, 1st decade and 7th decade. 4) Duodenitis was slightly higher in after 4th decade than before 4th decade. 5) The 56 cases of duodenitis except for 1 case were aasociated with gastroduodenal diseases such as gastritis, peptic ulcer or gastric carcinoma. Association of gastritis is highest as 79. 4%. 6) Acurracy of diagnosis in duodenitis on X-ray study was 3 cases in 20 cases. Generally X-ray study was little value in diagnosis of duodenitis.