회원작품: 상하이 엑스포 2010 : 한국관

박기수,조민석,Park, Ki-Su,Cho, Min-Suk 대한건축사협회 2010 建築士 Vol.2010 No.7

욕망의 회로에 갇혀버린 기표의 운동과 권력효과

박기수,Park, Gi-Su 대한출판문화협회 2001 출판저널 Vol.313 No.-

무인기 기반 RGB 영상 활용 U-Net을 이용한 수수 재배지 분할

박기수,유찬석,강예성,김은리,정종찬,박진기,Kisu Park,Chanseok Ryu,Yeseong Kang,Eunri Kim,Jongchan Jeong,Jinki Park 대한원격탐사학회 2023 大韓遠隔探査學會誌 Vol.39 No.5

When converting rice fields into fields,sorghum (sorghum bicolor L. Moench) has excellent moisture resistance, enabling stable production along with soybeans. Therefore, it is a crop that is expected to improve the self-sufficiency rate of domestic food crops and solve the rice supply-demand imbalance problem. However, there is a lack of fundamental statistics,such as cultivation fields required for estimating yields, due to the traditional survey method, which takes a long time even with a large manpower. In this study, U-Net was applied to RGB images based on unmanned aerial vehicle to confirm the possibility of non-destructive segmentation of sorghum cultivation fields. RGB images were acquired on July 28, August 13, and August 25, 2022. On each image acquisition date, datasets were divided into 6,000 training datasets and 1,000 validation datasets with a size of 512 × 512 images. Classification models were developed based on three classes consisting of Sorghum fields(sorghum), rice and soybean fields(others), and non-agricultural fields(background), and two classes consisting of sorghum and non-sorghum (others+background). The classification accuracy of sorghum cultivation fields was higher than 0.91 in the three class-based models at all acquisition dates, but learning confusion occurred in the other classes in the August dataset. In contrast, the two-class-based model showed an accuracy of 0.95 or better in all classes, with stable learning on the August dataset. As a result, two class-based models in August will be advantageous for calculating the cultivation fields of sorghum.

'과학사 기반 화학자 탐구 프로그램'이 고등학교 과학영재의 과학의 본성에 대한 인식과 과학적 태도, 과학 진로지향도에 미치는 영향

박기수,유미현,Park, Gi-Su,Yoo, Mi-Hyun 대한화학회 2013 대한화학회지 Vol.57 No.6

The purpose of this study was to develop 'Science History Based Chemist Inquiry Program' for the science-gifted in high school and investigated the application effects on the understanding toward the nature of science, scientific attitudes, and science career orientation. This study was conducted with one class of 17 scientifically gifted high school students, and the 'Science History Based Chemist Inquiry Program' was applied during 22 class hours. The results of this study were as follows: First, the science gifted students' understanding toward the nature of science showed a statistically significant improvement (approximate significance probability .005). Property of the scientific model, sub-domain of the nature of science, is significantly improved (approximate significance probability .029). This result show that 'Science History Based Chemist Inquiry Program' can improve the scientifically gifted high school students' perception about nature of science. Second, the scientifically gifted students' scientific attitude wasn't changed significantly. However, the openness and creativity in the sub-domains of the scientific attitude showed a statistically significant improvement (p<.05). Third, science career orientation of science-gifted did not show a statistically significant change. But the value of the level of awareness about the science career has been significantly improved (p<.05). 본 연구는 고등학교 과학영재의 특성에 맞는 '과학사 기반 화학자 탐구 프로그램'을 개발하고 과학의 본성에 대한 인식과 과학적 태도, 과학 진로지향도에 미치는 영향을 살펴보고자 진행되었다. 본 연구의 대상은 고등학교 부설 영재학급에 선발되어 교육받는 영재학생 1학급 17명이며, '과학사 기반 화학자 탐구 프로그램'은 22차시에 걸쳐 적용되었다. 본 연구결과를 요약하면 다음과 같다. 첫째, 과학영재의 과학의 본성에 대한 인식은 통계적으로 유의미한 향상을 보였다(근사유의확률 .005). 과학의 본성 하위 요소 중에서는 '과학적 모형의 속성'에서 유의미한 향상을 보였다(근사유의확률 .029). 이는 '과학사 기반 화학자 탐구 프로그램'이 고등학교 과학영재의 과학의 본성에 대한 인식을 향상시킬 수 있음을 보여준다. 둘째, 과학영재의 과학적 태도에 통계적으로 유의미한 변화가 나타나지 않았다. 과학적 태도의 7가지 하위 영역 중 개방성과 창의성은 통계적으로 유의미한 향상을 보였다(p<.05). 셋째, 과학영재의 과학 진로지향도에 통계적으로 유의미한 변화가 나타나지 않았다. 그러나 과학 진로에 대한 가치 인식 수준은 유의미하게 향상되었다(p<.05).

Zygotic Expression of c-myc Gene in Mouse Early Embryos: Functional Role of c-myc Promoter

박기수,강해묵,심찬섭,선웅,김재만,이영기,김경진,Park, Ki-Soo,Kang, Hae-Mook,Shim, Chan-seob,Sun, Woong,Kim, Jae-man,Lee, Young-Ki,Kim, Kyung-jin The Korean Society for Integrative Biology 1995 동물학회지 Vol.38 No.4

c-myc proto-oncogene은 여러 세포들의 분화와 형질전화에 뿐만 아니라 정상세포의 분열조절에도 관여한다고 알려져왔다. 특히 생쥐의 초기배아에서 c-myc mRNA가 발현되고 antisense c-myc oligomer의 미세주입에 의해 배발생이 억제된다는 연구결과는 c-myc이 초기배아의 발생 및 분열에 관여하는 것을 시사한다. 그러나 최근까지 초기배아에 존재하는 c-myc promoter의 기능적 활성화에 관한 연구는 미진하였다. 이를 위하여, c-myc promoter와 대장균의 lacZ 유전자를 결합시킨 두 종류의 vector(pcmyc-Gall, pcmyc-Ga12)를 만들어 수정란의 전핵에 미세주입한 후, 배 발생에 따른 c-myc promoter의 활성화를 lacZ 유전자의 산물인 $\beta$-galactosidase 에 의한 X-gal 염색으로 조사하였다. 미세주입된 초기 배아는 2세포기 배아를 포함하는 여러 발생단계에서 $\beta$-galactosidase 의 활성을 보였다. 이는 c-myc 유전자가 배아의 게놈유전자로부터 발현되며, 또한 궁극적으로 초기 배아의 발생과정에 중요한 역할을 하고 있음을 시사하고 있다. The c-myc proto-oncogene is Involved In the control of normal cell proliferation and differentiation of many cell lineages. Although it has heen suggested that c-myc may play an important role in the mammalian early development, it Is unclear whether the embryonic c-myc mRNA is originated from zygotic gene expression or stored maternal message. Thus, we have construded expression vectors, In which the 5, flanking sequences including c-myc promoter region and a large non-coding exon I are fused 'sith E. coli lacZ gene that encedes $\beta$-galactosldase as a reporter. As c-myc exon I contains a modulatory sequence, we designed t, vo types of vectors (pcmyc.Gall and pcmyc-Ga12) to examine the role of exon I in c-myc expression. The former contains the complete exon I and the later has a deletion in 40 bp of modulator sequence located In the exon I of c-myc These vectors were microInjected into fertilized one-cell embryos and $\beta$-galactosidase activity was examined by X-gal staining during early embryogenesis. $\beta$-galactosidase activity derived from c-myc promoter was decreased at two-cell stage. The expression level directed by pcmyc- Ga12 was similar to that of pcmyc-Gal1, indicating that the medulatory sequence in exon I may not be Involved at least In the regulation of embryonic c-myc expression. In summary, the present study indicates that the c-myc promoter is functional at the early stage embryo, and the regulation of c-myc expression is under the control of "zygotic" clock of preimplantation mouse embryos.e embryos.

DFT방법을 이용한 Bis(μ-oxo)dicopper-enzyme의 수소이동반응 연구

박기수,김용호,Park, Ki-soo,Kim, Yong-Ho 대한화학회 2009 대한화학회지 Vol.53 No.5

금속은 생명현상에 필수적인 효소반응에서 핵심적인 역할을 수행한다. 따라서 금속효소 안에서 일어나는 반응에 대한 구체적인 메커니즘은 많은 과학자의 오랜 관심사였다. Methane MonoOxygenase (MMO)는 메탄을 메탄올로 산화시키는 반응을 일으키는 효소이며 최근 Tolman등은 MMO의 모델로서 Bis(μ-oxo)dicopper Complexes의 Hydroxide Transfer 반응에 대한 몇 가지 가능한 메커니즘을 제시하였다. 이후 Hydrogen Transfer와 Hydroxide Rebound의 2단계로 이루어지는 메커니즘이 이론적으로 제시 되었다. 본 연구에서는 Bis($\mu$-oxo)dicopper Complexes 의 반응단계 중 첫 번째 단계인 Hydrogen Transfer 반응과정의 반응물과 전이상태, 생성물의 구조를 최근에 개발된 M06계열의 M06, M06L, M06-2X를 비롯한 여러 가지 DFT방법을 이용하여 계산하였다. M06/6-31G(d,p)/LANL2DZ방법을 사용하여 계산된 반응물의 구조가 실험에서 얻은 XRD구조와 가장 잘 일치했으며 기저함수의 크기에 따라 전이상태의 구조, 활성화 에너지 및 반응에너지에 큰 차이를 보였다. Metals have often played important roles to some enzymatic reactions that are essential to biological processes. Therefore many scientists have studied the reaction mechanisms of catalytic reactions in metaloenzymes for many years. Methane MonoOxygenase (MMO) is an enzyme that oxidize methane to methyl alcohol. Recently Tolman et al. studied a model reaction for MMO, which is a hydroxide transfer reaction in Bis-($\mu$-oxo)-dicopper complex, and suggested several possible mechanisms. Later a two-step mechanism, which is hydrogen transfer followed by hydroxide rebound, was proposed from theoretical studies. In this study we calculated the reactant, product, and the transition state structures, and energetics of the first hydrogen transfer reaction using various DFT methods including recently developed the MO6 family of DFT, namely, MO6, MO6L, and MO6-2X. We found that the M06/6-31G(d,p)/LANL2DZ method reproduce the experimental XRD structure of reactants very well. The TS structures, barrier heights, and reaction energies depend very much on the size of the basis sets.

종합서평 - 젊은 시인들이 그리는 내면의 사생화

박기수,Park, Gi-Su 대한출판문화협회 2000 출판저널 Vol.285 No.-

수소화합물 상온초전도의 발견과 도전

박기수,서순범,박두선,Park, Gi-Su,Seo, Sun-Beom,Park, Du-Seon 한국초전도저온학회 2021 초전도와 저온공학 Vol.23 No.2

'도식성'과 '현실도피' 원리로 우세종 된 대중문학

박기수,Park, Gi-Su 대한출판문화협회 2001 출판저널 Vol.296 No.-

음양조화원리(陰陽調和原理)를 통한 동서의학(東西醫學) 회통(會通)

박기수,이시형,Park, Ki-Soo,Lee, Si-Hyeong 대한한의정보학회 2012 大韓韓醫情報學會誌 Vol.18 No.1

The topic of this study is to ask and answer about 'What matters most in medicine'. And the purpose of this study is to establish paradigm which guarantee 'the original principles of science in medicine' and 'the safety of human life in medicine'. The organized characteristics of this study is as follows. 1. 'The harmony of nature (heaven, earth and human)' is the base of medicine. Because medicine control life directly and all life is 'the son of nature'. 2. 'The harmony of Eum and Yang' is the essential power of universe and the key of metabolism of all life including human, animals and plants. Because 'the nature of universe' and all 'Life field' is 'electro-magnetic field'. 3. The Convergence of Oriental medicine and Western medicine orients 'the harmony of Eum and Yang'.