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RISS 인기검색어
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- 저자 : 류정일(Jung Il Ryu) (검색결과 4 건)
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항사구체 기저막 항체 및 p - ANCA 양성인 급속 진행성 사구체신염 1 예
류정일(Jung Il Ryu),조규현(Kyu Hyun Cho),허성욱(Seong Wook Heo),권현희(Hyun Hee Kwon),조창호(Chang Ho Cho),안기성(Ki Sung Ahn),이인희(In Hee Lee) 대한신장학회 2002 Kidney Research and Clinical Practice Vol.21 No.4
Rapidly progressive glomerulonephritis(RPGN) is clinical syndrome characterized by rapid loss of renal function within several weeks to months, with histologic finding of extensive crescent formation. We report a case of RPGN associated with anti-glomerular basement membrane antibody(anti-GBM Ab) and perinuclear-antineutrophilic cytoplasmic antibody(p-ANCA), which rapidly progressed to chronic renal failure. A 44-year-old male was referred to our hospital for evaluation of pitting edema and proteinuria. Both anti-GBM Ab and p-ANCA were detected in serum. Percutaneous renal biopsy showed many crescents with some fibrinoid materials and heavy deposits of IgG. He was treated with pulse methylprednisolone, followed by oral corticosteroid and cyclophosphamide. In spite of immunosuppressive therapy, his renal function deteriorated rapidly and uremic symptoms including pulmonary edema were aggravated. He was started on hemodialysis and he has received regular hemodialysis without recovery of renal function. Further studies will be needed to determine the clinical significance of combined anti-GBM Ab and ANCA.
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Su Noh Ryu(柳守魯),Jung Il Lee(李正日),Chul Whan Kang(姜哲煥) 한국육종학회 1995 한국육종학회지 Vol.27 No.3
This study was conducted to obtain basic informations on the unsaponifiable components in sesame seed. Four major lignan, sesamin, sesamolin, sesamol and sesangolin were analyzed to provide fine separation of unsaponifiable component fractions of seed oil in four wild and three cultivated sesame varieties by thin layer chromatography (TLC). The mean content of unsaponifiable components extracted from cultivated sesame oil was 2.4% (ranged 2.2 to 2.7), while that of wild ones showed 3.3% (ranged 2.3 to 4.0). The mean content of unsaponifiable components of wild species was higher than that of cultivated ones. Silicagel plates and chloroform/diethyl ether (9 : 1, v/v) as mobile phase on the first and second directions were utilized in TLC analysis. In one-dimensional TLC separation, sesamin, sesamolin, sesamol, sesangolin and tocopherol were identified as spots at the Rf values of 0.66, 0.76, 0.52, 0.66 and 0.88, respecitively. Sesamin and sesangolin were appeared at same spots with Rf value of 0.66. In two-dimensional TLC separation, sesamin and sesangolin showed different TLC pattern. This two-dimensional system could be adopted to provide pure fractions in preparative experiments for sesamin and sesangolin measurements of seed oil. Some other minor spots were also observed in S. alatum and S. radiatum showing void of sesamolin but containing sesangolin.
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기존 원발성 막성 신병증에 합병된 반월상 사구체신염 1 예
임상혁(Sang Hyuk Lim),권현희(Hyun Hee Kwon),박경찬(Kyoung Chan Park),류정일(Jung Il Ryu),유성수(Sung Soo You),박민식(Min Sik Park),조창호(Chang Ho Cho),김용진(Yong Jin Kim),안기성(Ki Sung Ahn),이인희(In Hee Lee) 대한신장학회 2002 Kidney Research and Clinical Practice Vol.21 No.5
Membranous nephropathy (MGN) is a common cause for nephrotic syndrome in adults. Renal failure usually develops gradually in patients with MGN and rapid deterioration of renal function is a rare complication. Moreover, the development of crescentric glomerulonephritis (CGN) as a cause of acute renal failure (ARF) in patients with preexisting MGN is very rare. We report 20-year-old male patient with MGN who presented with ARF due to superimposed CGN. He had been diagnosed as idiopathic MGN and his renal function was maintained within normal range. After 13 months of conservative treatment, ARF was developed and renal biopsy was performed to differentiate the possible causes of ARF. Renal biopsy revealed diffuse crescents formation on preexisting MGN. Anti-GBM antibody and ANCA were not detected. This patient was treated with combination therapy including methylprednisolone pulse therapy followed by high dose steroid and cyclophosphamide. His renal function was improved significantly 2 weeks after treatment. In conclusion, when unexplained ARF in patient with MGN develops, prompt investigation for superimposed conditions including CGN is necessary and repeat renal biopsy should be considered.
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주동욱 ( Dong Wook Joo ),김병석 ( Byung Seok Kim ),하경호 ( Kyung Ho Ha ),박경찬 ( Kyoung Chan Park ),류정일 ( Jung Il Ryu ),이창형 ( Chang Hyeong Lee ) 대한내과학회 2012 대한내과학회지 Vol.82 No.4
Background/Aims: Toxocariasis rarely causes a liver abscess. We assessed clinical and laboratory manifestations as well as therapeutic responses in patients with toxocariasis presenting as a liver abscess. Methods: Fourteen patients with toxocariasis presenting as a liver abscess were analyzed retrospectively. Symptoms, occupational history, dietary habits, contact with pets, allergic disease, peripheral eosinophil count, serum immunoglobulin E (IgE) level, and invasion to other organs were evaluated. After treatment with albendazole, follow-up was conducted with abdominal computed tomography (CT) and the measurement of serum eosinophil and IgE levels. Results: Among 568 patients with a liver abscess, 14 were diagnosed with active toxocariasis. The mean age of the patients was 48 years, and nine (64%) were men. Four (28.6%) patients had pain in the right upper quadrant of the abdomen or epigastric area, one had cough, and the others (64.3%) had no symptom. Pulmonary involvement was noted in five patients and colon involvement in one. Six (42.9%) patients had a recent history of eating raw meat. Initial laboratory findings showed increased eosinophil and IgE levels in all patients. The initial CT showed one or multiple ill-defined, hypodense lesions in the liver. After 1 month of albendazole treatment, eosinophil counts were normalized or had decreased in 13 (93%) patients. On follow-up CT, liver abscesses disappeared within 6 months after therapy in 92% of patients. Conclusions: Symptoms, laboratory findings, and treatment of a liver abscess caused by toxocariasis differ from those of a pyogenic liver abscess. Early serologic testing may increase diagnostic yield and efficacy of treatment in patients with a liver abscess and peripheral eosinophilia. (Korean J Med 2012;82:435-440)
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