한센인 정착촌에 대한 현상학적 연구

노상근,이인수 한국노인복지학회 2017 한국노인복지학회 학술발표논문집 Vol.7 No.1

본 연구는 한센인의 모여삶이란 공간인 `한센인 정착촌`이 그들에게 어떠한 도움을 주어왔는지, 지금은 어떠한 것인지, 앞으로는 어떠해야 하는지 등을 해명하기 위하여 그들의 경험적 사실로부터 공통적 의미와 주제를 발견해 내고자 하는 연구다. 속칭 나환자라는 이유로 과거의 격리 정책과 사회로부터 소외되며 살아온 그들의 체험 현상들이 우리 사회의 구조와 인식 속에 어떻게 존재하여 왔고 어떻게 변화되어 왔는지 반성적 맥락에서 분석해 본 연구다. 충남 서산시 운산면에 소재한 한센인 정착촌 영락원에 거주하는 한센노인들은 그들에 가해진 온갖 고난을 운명 지워진 삶으로 받아들이고 있었으며 정착촌은 다음과 같은 의미를 지니고 있었다. 첫째, 낯선 세계로의 추방 공간이라는 의미를 지니고 있었다. 한센인 정착촌은 처음부터 필요에 의하여 조성된 공간 이라기보다는 성한 사람들의 세계에서 이들을 분리하고 격리하기 위한 필요에 의하여 조성된 공간이었다. 둘째, 대다수 건상한 사람들의 지배이데올로기에 의해 발생된 피해 현장이라는 의미를 지니고 있었으며 인간의 가치와 존엄이 짓밟힌 현장인 동시에 지배 이데올로기에 의한 가해공간이며 그들에게는 인간의 가치와 존엄이 철저히 무시되는 피해 현장이었다. 셋째, 그럼에도 불구하고 정착촌은 사회 약자들의 안식처요 보금자리의 의미를 지닌 공간이었다. 한센인은 같은 처지의 사람끼리 편하게 대화 할 수 있는 공간이 주어진 것만으로도 그들에게는 큰 위로요 안식처며 인생의 길동무가 되었다. 정착촌은 한센인에게 심리적 안식을 주고 있는 공간이었다. 문제들을 해소하기 위한 방안으로는 한센인문제의 특수성을 이해하고 이를 보편적인 인권문제로 인식하여 사회복귀의 장애요소를 제거하는 일이다. 한센인의 경험과 현실을 공유하면서 꾸준한 교육과 홍보를 통해 한센인의 완전한 사회복귀를 가능하게 하는 구체적 프로그램을 시행하여야 할 것이다.

혈소판농축액 보관 시 교반 중단 및 백혈구의 제거가 혈소판의 품질에 미치는 영향

노상근,정의석,최원철,위재호 대한진단검사의학회 2008 Annals of Laboratory Medicine Vol.28 No.3

Background : This study aimed to analyze the influence of the interruption of agitation and removal of leukocytes on platelet concentrates (PCs), and determine the maximum amount of time the agitation could be interrupted without impairing PCs’ effectiveness during the storage period. Methods : Four ABO-identical random donor platelets agitated for 24 hr were pooled, and divided into 4 units, and 2 units of them were leukoreduced. Then 52 pooled units were categorized into 4 groups, non-leukoreduced continuous agitation (Non-LRCA), non-leukoreduced interrupted agitation (Non-LRIA), leukoreduced continuous agitation (LRCA), and leukoreduced interrupted agitation (LRIA), and preserved for 6 days (total 7 days). Mean platelet volume (MPV), pH, HCO3 -, pO2, pCO2, CD62P, CD61, glucose, lactate, ammonia and free fatty acid were measured during the period. Results : Starting from the Day 4, the pH and HCO3 - of Non-LRIA group begun to decrease while the amount of lactate production, glucose consumption, and MPV increased compared to the Non- LRCA group (P<0.01). An increase in pO2 level was observed in the interrupted agitation groups as the storage period prolonged (P<0.01). The pH levels of all the units in the agitation groups remained higher than 6.4 up to Day 7, while those of the non-leukoreduction group did so only up to Day 2, but those of leukoreduction in the interrupted agitation groups did so up to Day 4. Conclusions : The interruption of agitation reduced the platelet’s capacity to utilize oxygen, increasing lactate amount and reducing pH level. However, the in vitro parameters of the Non-LRIA and Non-LRCA groups on Day 2 were similar to each other and the pH level remained at 6.4 or higher, making one day of agitation interruption possible after 24 hr of agitation. With leukocytes removed, the effective agitation interruption period may become longer. (Korean J Lab Med 2008;28:221-9)

原著(원저) : 병원종사자들의 수혈혈액에 대한 신뢰와 만족에 관한 조사

노상근 ( Sang Keun Roh ) 대한임상병리사협회 2001 임상수혈검사학회 발표자료집 Vol.6 No.1

It is essential when performing a blood related business to secure safety and to improve the blood supply service while the significance is ever increasing. In this connection, this research is designed to survey hospital-engaged personnel' recognition, knowledge, reliability and satisfaction in relation to transfusions of blood, thus obtaining the basic data necessary for achieving safety in transfusion of blood and the efficient supply. The survey was conducted from 1 April to 18 April 2000, targeting 406 hospital-engaged personnel in eleven hospitals in Pusan. Its outcome is shown below. The overall recognition of and concern for blood transfusion were fair. By job, pathologists ranked the highest in concern over blood transfusions and doctors ranked the highest in transfusions. In addition, by hospital type, in the recognition of blood donation and in transfusion-related education participation, workers at ordinary hospitals ranked higher than those at university hospital. Necessity for self-supply of transfusion blood was fair and each hospital was passive in recommending designated blood donations (donation by custodians). University hospitals felt stronger than ordinary hospitals that they should recommend designated donations. "Request by patients and their custodians" was cited the most as reasons for designated transfusions and this was even more so with ordinary hospital than university hospitals. Exchange of information on transfusions of blood was very low and in the number of the exchange, doctors were rated the highest. In blood transfusion-related contacts, pathologists ranked the highest. In addition, the number of contacts with the Red Cross Blood Center, university hospital worker were more frequent than those at ordinary hospitals, while in the transfusion-related public, workers at ordinary hospital had stronger showings. Knowledge in blood transfusions in terms of 16 points as a full mark, 6.62 on an average is relatively low. Also, doctors and pathologists cited the source of knowledge for transfusions of blood as specialized books, while nurses cited it as in-house education. The degree of overall reliability over supplied blood was fair and respondents were somewhat suspicious over items currently being checked designed to secure safety. By job, pathologists` reliability over them was the highest and by hospital type, the reliability of workers at ordinary hospitals was higher. The degree of satisfaction over transfusions of blood was fair and respondents were somewhat dissatisfied over items such as the supply, supply time, return, and exchange in relation to transfusion of hematological medicines. Also, in job satisfaction, pathologists were the most satisfied. By hospital type, workers at ordinary hospitals were a little bit more satisfied than those at university hospitals. Meanwhile, regression analysis on reliability and satisfaction in relation to blood transfusions shows that the more they exchanged information and the more positive and concerned they were, the higher the reliability and satisfaction over transfusions of blood.

Antidiabetic Synergetic Effects of Plant Extract-Mixtures in Streptozotocin-Diabetes Rats

Sang Geun Roh(노상근),Jong Hae Kim(김종해),Won Chul Choi(최원철) 한국생명과학회 2009 생명과학회지 Vol.19 No.3

본 연구는 streptozotocin (STZ)으로 당뇨를 유발한 실험쥐에 대한 Psidium guajava L. 잎(Pg), Lagerstroemia speciosa L. 잎(Ls) 추출물 그리고 혼합물 A (Pg, Ls, Morus indica L. 잎 추출물, Pinus densiflora needles 추출물, Acanthopanax senticosus M. roots 추출물)의 효과를 조사하였다. 4주간 streptozotocin (STZ)으로 당뇨를 유발한 실험쥐에 이들 추출물을 섭취시킨 결과 Pg, Ls 그리고 혼합물 A의 섭취는 당뇨 대조군에 비해 혈당을 각각 20%, 14% 그리고 24% 감소시켰다. 또한 이들 추출물의 섭취는 총 콜레스트롤, 중성지방, 유리지방산을 감소시켰고 인슐린과 HDL-콜레스트롤을 효과적으로 증가시켰다. 결론적으로 혼합물 A는 Pg와 Ls 추출물에 비해 혈당 및 지질감소, 인슐린 증가 효과 그리고 기능적으로 손상된 베타세포의 회복이 더 높은 것으로 나타났다. 따라서 혼합물 A는 개별적으로 사용한 Pg와 Ls 추출물에 비해 더욱 유익한 상승효과를 발휘하는 것으로 증명되었다. This study investigates the effects of Psidium guajava L. leaf (Pg), Lagerstroemia speciosa L. leaf (Ls) and mixture A (Pg, Ls, Morus indica L. leaf extract, Pinus densiflora needles extract, Acanthopanax senticosus M. root extract) on streptozotocin (STZ)-diabetes rats. For four weeks, STZ-diabetes rats were fed crystallized extracts of Pg, Ls, and mixture A. Compared to the diabetic control group, extracts of Pg, Ls, and mixture A decreased glucose levels in rats by 20%, 14% and 24% respectively. These extracts also decreased the level of total cholesterol, triglyceride and free fatty acid, compared to the diabetic control group, while effectively increasing levels of insulin and high-density lipoprotein- cholesterol. These results showed that mixture A had greater antihyperglycemic, antihyperlipidemic, and insulin-increasing effects than the Pg and Ls extracts. Mixture A also showed better restoration of damaged beta cell function compared to Pg and Ls extracts. Therefore, it was proved that mixture A provides a beneficial synergistic effect when compared with Pg and Ls extracts used individually.

Antidiabetic Effects of Leaves Extracts of Psidium guajava L. and Lagerstroemia speciosa L. in STZ-induced Rats

Sang Geun Roh(노상근),Kyun Ha Kim(김균하),Won Chul Choi(최원철) 한국생명과학회 2009 생명과학회지 Vol.19 No.1

구아바(Psidium guajava L.)와 바나바(Lagerstroemia speciosa L.)는 항당뇨 효과를 갖는 대표적인 약용식물로 알려져 있다. 이들 식물은 다양한 폴리페놀(polyphenol) 성분을 함유하며 당뇨병의 치료에 효과적으로 작용한다. 따라서 본 연구는 이들 추출물을 streptozotocin (STZ)으로 당뇨를 유발한 실험쥐에 섭취시켜 항당뇨 효과를 상호 비교하였다. STZ으로 당뇨를 유발한 실험쥐에 구아바 및 바나바 잎 추출물을 섭취시킨 결과 당뇨쥐에 비해 혈당은 약19-32%, 총콜레스테롤(total cholesterol)은 약 24-46%, 중성지방(triglyceride)은 22-67% 그리고 유리지방산(free fatty acid)은 49-71% 감소하였고 또한 인슐린 분비와 췌장에 존재하는 베타세포의 회복도 증가되었다. 한편 구아바 추출물의 섭취가 바나바 추출물의 섭취에 비해 항당뇨 효과가 더 높았는데 그 이유는 바나바 잎에 포함된 친수성 폴리페놀(polyphenol) 성분이 에탄올 추출과정에서 대부분 추출되지 않았고 또한 추출된 코로소릭산(corosolic acid)은 지금까지 알려진 것과는 달리 항당뇨 활성이 낮았기 때문이다. Guava (Psidium guajava L.) and banaba (Lagerstroemia speciosa L.) are well known as medicinal plants for their antidiabetic effects. These contain a great deal of polyphenol compound and work on the treatment of diabetes mellitus effectively. In this study, the extracts of guava and banaba are consumed by streptozotocin (STZ) induced diabetic rats to compare the antidiabetic effects. According to the comparison result, the glucose level of those STZ-induced diabetic rats has decreased by 19-32%, total cholesterol by 24-46%, triglyceride by 22-67% and free fatty acid by 49-71% approximately compared to the diabetic rats, while the generation of insulin and the recovery of beta cells have increased. However, the result showed that the antidiabetic effect of guava extracts was higher than that of banaba extracts. This is because the hydrophilic polyphenol compounds contained in banaba leaves were not extracted during the ethanol extraction process, and the antidiabetic activity of the extracted corosolic acid was low to surprise.

Antidiabetic Synergistic Effects of Medicinal Plant Extract Mixtures on db/db Mice

Sang Geun Roh(노상근),Won Chul Choi(최원철) 한국생명과학회 2011 생명과학회지 Vol.21 No.2

본 연구는 db/db mice에 대한 구아바 잎(Pg), 바나바 잎(Ls) 추출물 그리고 혼합물 A (바나바, 구아바, 뽕, 솔잎 그리고 가시오가피 뿌리 추출물)의 효과를 조사하였다. 4주간 db/db mice에 이들 추출물을 섭취시킨 결과 Pg, Ls 그리고 혼합물 A의 섭취는 당뇨 대조군에 비해 체중, 혈당, 인슐린을 감소시켰으며 이들 중에서 혼합물 A의 감소효과가 가장 높았다. 이들 추출물은 당뇨 대조군에 비해 총 콜레스테롤, 중성지방, 유리지방산을 감소시켰으며 이들 중에서 혼합물 A의 항고지혈증 효과가 가장 뛰어났다. 또한 혼합물 A는 당뇨 대조군에 비해 Langerhans’ islets의 손상을 유의하게 감소시켰다. 따라서 혼합물 A는 포함된 구성물질의 상호보완적인 약리작용에 의해 체중증가의 부작용이 없이 고혈당을 개선시키는 유익한 상승효과를 발휘한 것으로 나타났다. This study investigates the effects of Psidium guajava L. leaf (Pg) extract, Lagerstroemia speciosa L. leaf (Ls) extract, and mixture A (Pg, Ls, Morus indica L. leaf, Pinus densiflora needles, Acanthopanax senticosus M. roots extract) on db/db mice. For four weeks, db/db mice were fed powdered extracts of Pg, Ls, and mixture A. Compared to the diabetic control, extracts of Pg, Ls and mixture A decreased body weight, glucose and insulin. The greatest decreases were caused by mixture A. These extracts decreased the levels of total cholesterol, triglyceride and free fatty acid compared to the diabetic control. The antihyperlipidemic effect of mixture A was the greatest. Mixture A also significantly decreased injuries of Langerhans’ islets compared to the diabetic control. Mixture A showed a beneficial synergistic effect due to the supplementary pharmacological actions of the ingredients in contains, indicating that it improved hyperglycemia without the side effect of weight gain.

원어민 활용수업과 학습 동기가 학습자의 주의력과 지각에 미치는 영향

신동로,노상근,박윤자 全北大學校 敎育大學院 2003 敎育論叢 Vol.23 No.-

The purpose of this study is to investigate the effect of the communicative approach by a native speaker of English and the learning motivation on the learner's attention and perception. There was a basic study about the process of attention and perception of students through cognitive psychology. How the communicative approach of a native speaker of English or motivation work towards the attention and perception of students was studied. The subjects in this experimental study were one hundred and one middle school students. The number of items asked were 42 questions including the concept of motivation, attention. perception and learning after class. Especially four hypotheses were studied through multiple regression analysis. The results were as follows: There was little difference between teaching English through team-teaching with a native speaker of English and that with only a Korean teacher in the attention and perception of students. The close relation between intrinsic motivation and attention or perception of students was examined. It was also found that the higher level of extrinsic motivation contributes to the attention of students through the interrelation with the communicative approach.

HCV 항체 양성인 헌혈자군에서 정성 및 정량 HCV-RNA 측정

위재호,노상근,박수진 大韓輸血學會 2002 大韓輸血學會誌 Vol.13 No.2

외국어 학습에서 일반 언어불안과 독해불안과의 관계

신동로,권영선,노상근 全北大學校 敎育大學院 2001 敎育論叢 Vol.21 No.-

This study is to investigate the relationship between generally recognized language anxiety and reading anxiety in foreign language learning. The subjects of this article consisted of 77 lst grade middle school students and 82 2nd grade high school students. The total of 159 participants took part in this study. Two inventories assessed two different anxiety levels: the Foreign Language Classroom Anxiety Scale and Reading Anxiety Scale. For statistical analysis, the analysis of variable and correlation analysis were applied by using the SPSS computer program. The results of from the statistical analysis are as follows. · The relationship between generally recognized language anxiety and reading anxiety scale were highly related to each other(r=736). · A statistical correlation was not found between boys and girls, and between middle school and high school students in language and reading anxiety. · The reading comprehension assessment measures consisted of the translation of sentences and a multiple-choice test. The results indicated that more highly anxious students(those with high scores on reading anxiety inventory) tended to take less academic achievements than did those participants who claimed to experience minimal anxiety. · The listening assessment measures were multiple-choice tests. The results indicated that more highly anxious students(those with high scores on language anxiety inventory) tended to get less grades than did those participants who claimed to experience minimal anxiety. · This paper advocates that language anxiety and reading anxiety can play a significant causal role in creating individual differences in both language reading and listening.

추출용매 변화에 따른 바나바(Lagerstroemia speciosa Pers.) 잎 추출물의 항당뇨 효과

김균하(Kyun Ha Kim),노상근(Sang Geun Roh),이춘일(Chun-Ri Li),김춘봉(Chun-Feng Jin),김안드레(Andre Kim),최원철(Won Chill Choi) 한국생명과학회 2008 생명과학회지 Vol.18 No.9

본 연구는 바나바 잎 추출 용매에 따른 항당뇨 효과에 관한 것으로 세포 독성 실험을 통하여 인체에 대한 독성이 없음을 확인하였고 β-cell 인슐린 분비 실험을 통하여 항당뇨 효과를 알아보았다. 또한 당뇨 유발쥐를 이용한 인슐린 분비 실험, 체중변화 측정, 혈중 및 혈청의 glucose 농도, 총콜레스테롤 수치, HDL-cholesterol 농도, triglyceride 농도, free fatty acid 농도, langerhans islet에서의 인슐린 분비의 확인을 통해 혈당조절 효과를 비교하였다. 물 혹은 에탄올을 단독으로 이용하여 추출한 추출물이나 70%, 90% 에탄올로 추출한 추출물 보다 열수로 먼저 추출한 후 에탄올로 다시 추출하여 혼합안 추출물이 항당뇨 효과가 더 뛰어남을 알 수 있었다. 이는 친수성(hydrophilic) 유효성분들과 소수성(hydrophobic) 유효성분들의 추출 유무나 함량에 의한 것이다. 특히, 많은 문헌에 언급된 코로소린산이라는 단일 성분(unique)에 의한 항당뇨 효과라기보다는 친수성 및 소수성 폴리페놀 및 항산화성분과 같은 유효성분들이 조합되어(mixture) 항당뇨 효과에 영향을 미치는 것으로 사료된다. This study investigated that the antidiabetic effects of banaba extracts with variety solvents selectivity in vitro and in vivo. Banaba extracts were prepared with water, 70% ethanol, 90% ethanol, 100% ethanol and water-ethanol that of extract twice times sequentially water and ethanol. Cell toxicity and insulin secretion of banaba extracts was tested by MTT (3-[4,5-dimetylthiazol-2-yl]-2,5-diphenyltetrazolium bromide) assay on hamster insulinoma cell line, HIT-T15. Also we tested that insulin, body weight, blood glucose, total cholesterol, HDL-cholesterol, triglyceride and free fatty acid in streptozotocin diabetic rats. Water-ethanol extract has remarkable antidiabetic effect compare with the other banaba extracts. For water-ethanol extract has both of hydrophilic and hydrophobic antidiabetic materials from banaba. Expecially, corosolic acid, as known as unique polyphenol, has antidiabetic effect studied by many researchers till nowadays. But corosolic acid does not solve in water. Otherwise, we suggest that banaba extract of hydrophilic and hydrophobic materials (polyphenol and antioxidants) mixture more increased antidiabetic effects.