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숙지황과 가시오가피 복합추출물(OPB)이 난소절제 흰쥐의 골밀도 및 골대사에 미치는 영향
김정근,김세원,이병의,황현환,권종석,고선일,Kim, Jung-Keun,Kim, Se-Won,Lee, Byung-Eui,Hwang, Hyeon-Hwan,Kwon, Jong-Seok,Ko, Seon-Yle 대한안면통증구강내과학회 2007 Journal of Oral Medicine and Pain Vol.32 No.1
본 연구는 숙지황과 가시오가피 복합추출물 (OPB)이 난소절제 흰쥐의 골밀도 및 골대사 변화에 미치는 영향을 관찰하기 위하여 수행하였다. 13주된 20마리의 Sprague-Dawley 암컷 흰쥐를 대조군과 실험군으로 나누었고, OPB의 골밀도 및 골대사 변화에 대한 효과를 관찰하기 위하여 난소절제 후 3일 후부터 OPB를 100 mg/kg씩 8주 동안 경구투여 하였다. pQCT 방식으로 골밀도, 골함유량, 골강도를 측정하였고, 혈청 중 CTx (C-telopeptide of type I collagen)의 변화를 관찰하였다. 난소절제 후 대조군의 골밀도는 $-29.8{\pm}3.0%$로 현저히 감소하였으며, 이러한 감소는 OPB의 투여에 의해 $-21.4{\pm}2.3%$로 억제되었다. 골강도의 변화에서는 anti-fracture 값과 anti-twisting 값이 대조군에 비해 OPB 처리군에서 유의성 있는 차이를 나타냈다. 또한 혈청 중 골흡수 지표인 CTx 농도는 대조군에 비해 OPB 처리군에서 낮게 나타났다. 이상의 결과로 숙지황과 가시오가피의 복합 추출물인 OPB가 난소를 절제한 흰쥐에서 골 소실을 억제하므로 임상에서 난소절제 후 또는 폐경 후 골다공증의 개선제로 이용될 수 있으리라 여겨진다.
선박 Night Vision 시스템용 Pedestal의 제어부 개발
김정근(Jung-Keun Kim),김종민(Jong-Min Kim),박기랑(Ki-Rang Park),백승훈(Seung-Hun Baek),송세훈(Se-Hun Song),진상훈(Sang-Hun Jin),정인(In Jung),황승욱(Seung-Wook Hwang),진강규(Gang-Gyoo Jin) 한국마린엔지니어링학회 2006 한국마린엔지니어링학회 학술대회 논문집 Vol.2006 No.-
This paper presents the design of a night vision system for vessels. Both a hardware system and software modules for stabilization control are developed. In order to stabilize each control axis, the two-degree of freedom(TDF) PID controller is designed and its parameters are tuned using a real-coded genetic algorithm(RCGA). Simulation demonstrates the effectiveness of the proposed system.
김종원,심재철,김정근,김정현,백경민,이현의,오병열,조현경,유호룡,김윤식,설인찬,Kim, Jong-Won,Shim, Jae-Chul,Kim, Jeong-Keun,Kim, Jung-Hyun,Baek, Kyung-Min,Lee, Hyun-Eui,Oh, Byeong-Yeol,Jo, Hyun-Kyung,Yoo, Ho-Rhyong,Kim, Yoon-Sik,Seol, 대한중풍순환신경학회 2005 대한중풍.순환신경학회지 Vol.6 No.1
1. Purpose : The purpose of this study was done to compare the sex, past history, hematologic relationship between the Cerebral infarction patients and the Cerebral hemorrhage patients. 2. Methods : We selected the two study groups. The one is 20 Cerebral infarction patients and the other 20 Cerebral hemorrhage patients with confirmed by Brain CT or MRI. We made an investigation into past history. We examined and made a comparative study of CBC, LFT, Na, K, Cl in the both group. 3. Result & Conclusion : In the Cerebral hemorrhage group, there were many patients with Hypertension and Diabetes mellitus than the Cerebral infarction group. In the Cerebral infarction group, there were many patients with abnormal RBC count with no significant. Also, ESR is higher than the other group. Between the Cerebral infarction and the other group, we discovered significant cases with abnormal triglyceride, ALP in the Cerebral infarction group(p<0.05). Abnormal triglyceride is known one of important risk factor of Cerebral infarction, but this study was significant in the Cerebral hemorrhage group. Also, ALP was significant in the Cerebral hemorrhage group. Therefore more extensive research is needed.
회귀모형(回歸模型)을 통(通)한 보건지표(保健指標)와 그에 영향(影響)을 미치는 요인(要因)에 관(關)한 연구(硏究)
윤치근 ( Chi Keun Yoon ),김정근 ( Jong Kun Kim ) 한국보건사회연구원 1987 保健社會硏究 Vol.7 No.1
The main purpose of this study is to discuss the relationship between health indicators and health affecting factors. Regression analysis is employed to detect the relationship between a health status indicator and eleven health affecting factors. 1. All the pairs of variables varied in accordance with our expectations for the interrelationship between pairs of variables. 2. Infant mortality rates showed a high interrelationship of over 0.95 with life expectancy. This result partly justified the hypothesis that, in developing countries, high infant mortality rates have largely contributed to lower life expectancy. It also means that we could choose one of them as a health status indicator instead of combining them. 3. From the results of the stepwise regression of overall countries, two equations for infant mortality and life expectancy were selected. These were: LYI=9.2001-0.2623LX7-0.5662LX9-0.4178LXII (Infant mortality) Y2=40.1727+0.1126X4+0.2328X9 (Life Expectancy) These two equations illustrate that infant mortality had a comprehensive correlation with the health services variables, and with socioeconomic variables and the life expectancy was most closely correlate! with socioeconomic variables. 4. The most striking relationship is the degree of correlation between health status and the adult literacy rates. Three possible explanations are offered. a) We can simply assume that the literacy rates represent the general level of education which in turn reflect the level of socioeconomic development. b) The adult literacy rates are presumably associated with cleanliness and hygiene, improved child care. The connection between literacy and health status is not immediately evident. The obvious link is the spread of health knowledge through health education. Both children and adutls may be taught to children at school and adults at adlut education courses. c) There seems to be a vicious circle between low level of education, poor-health and low incomes. Low incomes may limit educational opportunities, therefore, it is unlikely that productivity rates will rise. This low, productivity, in turn, will ensure incomes remain low. It brings a lack of food and adequate sanitation, so that poor health will prevail. In developing countries, the earnings difference between people with highest and lowest education levels would be expected to be greater since the totally uneducated have been even lower productivity levels than those of the primary school graduates. 5. The strong relationship between the number of physicians and health status is to be expected. One possible way to explain this high association may be simple. In theory, each country trains physicians to meet the medical problems of people and their activities are directly concerned with controlling physical and mental diseases. In spite of their direct effect on people`s health, physicians showed lower correlation with health status than did adult literacy rates. A tentative explanation might be a) The health training programes, especially in developing countries, are frequently irrelevant to local health problems, needs and demands, physicians prefer to perform highly sophisticated curative hospital work instead of primary health care services. b) In some countries, the private profit-making and urban oriented market for health services employs high proportions of physicians and this serves a comparatively small, selected client who can afford to pay for relatively sophisticated treatment. This is the most serious and pervasive deficiency in the geogr aphical maldistribution of physicians, which occurs widely in developing countries. The heavy concentration of physicians in the urban areas creates several problems. 6. The results of the analysis for the developed and developing countries are very different. The selected health affecting factors do not explain well the health status of the developed countries, in particular the physicians and the adult literacy rates show the greatest explanatory power for health status in developing countries. These results imply the suggestion that, in developed countries, the selected health services and socioeconomic factors generally have little effect on health.
이영세,최현국,김정근,이용희,정경태,노종수,서명교,Lee Young Sei,Choi Hyun Kuk,Kim Jung Keun,Lee Yong Hee,Chung Kyung Tae,Roh Jong Su,Suh Myung Gyo 한국환경보건학회 2004 한국환경보건학회지 Vol.30 No.5
Food waste is becoming by environmental problem nowdays increasing festinately in Korea during past 10 years. Food waste collected from garbage trucks that is offered in S municipal government that food waste mixs enough, and sewage sludge collected in the country. Composting experiment conditions achieved in the mixture ratio rate that food waste and sewage sludge are each 10:90, 30:70, 50:50, 60:40, 70:30 and 90:10 $wt\%$. The fermentation temperature was $18{\sim}22^{\circ}C$ at the beginning, and then it was sharply increased to $44{\sim}66^{\circ}C$ up to 1 day after fermentation, which was maintained for more than 3 days. Then, it was slowly decreased to $18{\sim}25^{\circ}C$ up to 8 days after fermentation, which was maintained all the time. It could be known from examiation of various conditions, including reaction rate, salinity. carbon/nitrogen(C/N) ratio, temperature, organic substance, etc.. Optimum mixture ratio rate of composting using food waste and sewage sludge was 60:40 $wt\%$.