두개골 성형술의 사용 재료와 수술 시기에 따른 감염율

김영우,유도성,김달수,허필우,조경석,김재건,강준기,Kim, Young-Woo,Yoo, Do-Sung,Kim, Dal-Soo,Huh, Pil-Woo,Cho, Kyung-Suck,Kim, Jae-Gun,Kang, Joon-Ki 대한신경외과학회 2001 Journal of Korean neurosurgical society Vol.30 No.2

Objective : Cranioplasty is required to protect underlying brain, to correct major aesthetic deformities, or both. The ideal material for this purpose is autogenous bone. When this is not available, alloplastic or artificial materials may be used. In this study authors compared the infection rate according to the cranioplasty materials(the frozen autologous bone vs. bone cement), and duration of the skull defect. Materials : Between May 1994 and December 1999, 111 patients with skull defect treated with cranioplasty(82 cases of frozen autologous bone and 29 cases of artificial bone material) were included in this study. There were 77 males and 34 females with a mean age of 41.4 years(range 1-85 years). 57 patients had head trauma and 54 had non-traumatic insults. According to the duration of skull defect, there were 28 cases under 1 month, 33 cases of 1-2 months, 15 cases of 2-3 months, 20 cases of 3-6 months and 15 cases over 6 months of duration. Results : Overall infection rate was 9.9%. In cases with frozen autologous bone and artificial bone material, the infection rate was 8.5% and 13.7%, respectively. The infection rate according to the duration of skull defect was 3.6%(among 28 cases) under 1 month of age, while those were 12%(4 among 33 cases) at 1-2 months, 20%(3 among 15 cases) at 2-3 months, 5%(1 among 20 cases) at 3-6 months and 13%(2 among 15 cases) over 6 months. Accoring to the underlying disease, the infection rate in traumatic cases was 12%(7 among 57 cases) and that in non-traumatic one was 3.7%(2 among 54 cases). Conclusion : From this study, it appears that skull defect should be repaired as soon as possible, because early cranioplasty can lower the infection rate. And surgeons could save the patients' cranial bone as possible as they can because autologous bone is not only cost effective in cosmatic purpose but lower the infection rate.

AlN-Al₂O₃ 계에서의 상압소결 질화물복합체

김영우,김규헌,김동현,윤석영,박홍채,Kim, Young Woo,Kim, Kyu Heon,Kim, Dong Hyun,Yoon, Seog Young,Park, Hong Chae 한국세라믹학회 2014 한국세라믹학회지 Vol.51 No.5

Particulate nitride composites have been fabricated by sintering the compacted powder of AlN and 5 - 64.3 mol% $Al_2O_3$, with a small addition of $Y_2O_3$ ($Y_2O_3$/AlN, 1 wt%), in 1-atm nitrogen gas at $1650-1900^{\circ}C$. The composites were characterized in terms of sintering behavior, phase relations, microstructure and thermal shock resistance. AlN, 27R AlN pseudopolytype, and alminium oxynitride (AlON, $5AlN{\cdot}9Al_2O_3$) were found to existin the sintered material. Regardless of batch composition, the AlN-$Al_2O_3$ powder compacts exhibited similar sintering behavior; however, the degree of shrinkage commonly increased with increasing $Al_2O_3$ content, consequently giving high sintered bulk density. By increasing the $Al_2O_3$ addition up to ${\geq}50 mol%$, the matrix phase in the sintered material was converted from AlN or 27R to AlON. Above $1850^{\circ}C$, a liquid phase was formed by the reaction of $Al_2O_3$ with AlN, aided by $Y_2O_3$ and mainly existed at the grain boundaries of AlON. Thermal shock resistance was superior in the sintered composite consisting of AlON with dispersed AlN or AlN matrix phase.

고령에서 발현한 척수외 혈관모세포종 - 증 례 보 고 -

김영우,김재건,유도성,허필우,조경석,김달수,강준기,Kim, Young Woo,Kim, Jae Keon,Yoo, Do Sung,Huh, Phil Woo,Cho, Kyuong Suck,Kim, Dal Soo,Kang, Joon Ki 대한신경외과학회 2001 Journal of Korean neurosurgical society Vol.30 No.2

Intradural extramedullary hemangioblastoma of the spinal cord is uncommon tumor. Symptom onset is typically in the forth decade. Complete excision offers the best chance for cure. We report a case of extramedullary hemangioblastoma of the spinal cord in old age. A 76 -year old man presented with 1 month history of paraparesis. Multiple enhancing lower thoracic and lumbar spinal masses were seen on magnetic resonance imaging(MRI). Surgical exploration for symptomatic lesion revealed intradural-extramedullary mass, which had hypervascularity. The excised spinal masses were diagnosed as hemangioblastoma. Postoperative course was uneventful and symptoms improved gradually.

Monitoring circulating tumor DNA by analyzing personalized cancer-specific rearrangements to detect recurrence in gastric cancer

김영우,Young-Ho Kim,송유라,Han-Seong Kim,심혜원,Shiv Poojan,엄방울,Myeong-Cherl Kook,주정남,홍경만 생화학분자생물학회 2019 Experimental and molecular medicine Vol.51 No.-

Circulating tumor DNA (ctDNA) has emerged as a candidate biomarker for cancer screening. However, studies on the usefulness of ctDNA for postoperative recurrence monitoring are limited. The present study monitored ctDNA in postoperative blood by employing cancer-specific rearrangements. Personalized cancer-specific rearrangements in 25 gastric cancers were analyzed by whole-genome sequencing (WGS) and were employed for ctDNA monitoring with blood up to 12 months after surgery. Personalized cancer-specific rearrangements were identified in 19 samples. The median lead time, which is the median duration between a positive ctDNA detection and recurrence, was 4.05 months. The presence of postoperative ctDNA prior to clinical recurrence was significantly correlated with cancer recurrence within 12 months of surgery (P = 0.029); in contrast, no correlation was found between cancer recurrence and the presence of preoperative ctDNA, suggesting the clinical usefulness of postoperative ctDNA monitoring for cancer recurrence in gastric cancer patients. However, the clinical application of ctDNA can be limited by the presence of ctDNA non-shedders (42.1%, 8/19) and by inconsistent postoperative ctDNA positivity.

일제 말기의 고등교육 제도-한국 근대 고등교육제도 변천사(완)

김영우,Kim, Yeong-U 한국대학교육협의회 1990 大學敎育 Vol.48 No.-

열분석법에 의한 Mg-8.5Li-4.5Al합금의 시효거동 연구

김영우,황영하,박태원,김도향,홍준표 ( Y . W . Kim,Y . H . Hwang,T . W . Park,D . H . Kim,C . P . Hong ) 한국열처리공학회 1997 熱處理工學會誌 Vol.10 No.4

Precipitation and strengthening mechanisms in squeeze cast Mg-8.5wt%Li-4.5wt%Al have been investigated by differential scanning calorimetry(DSC), scanning electron microscopy(SEM), in-situ and ex-situ X-ray diffraction analysis and hardness measurement. Special emphasis was placed on the investigation of the precipitation behavior by the DSC technique. Microstructural and calorimetric analysis showed that θ and δ precipitates in the b.c.c. β phase matrix, forming two exothermic peaks at the temperature ranges of 130℃∼180℃ and 236℃∼280℃. θ and δ dissolve into the matrix forming an endothermic peak at the temperature range of 280℃∼352℃. The as-cast microstructure consists of α, β and δ. Peak strength was obtained after aging for 1 hour at 50℃. The aging time required for the peak strength decreased as the aging temperature increases. The hardness decrease during overaging was due to the coarsening of θ precipitates. Microhardness measurement showed that variation of the hardness of β matrix was more pronounced than that of the α phase, indicating that the β phase is more responsible for the strengthening of the Mg-8.5wt%Li-4.5wt%Al alloy.

Mg-Li-Al(- Zr) 합금의 연화현상

김영우,황영하,임용진,김도향,홍준표 ( Y . W . Kim,Y . H . Kwang,Y . J . Lim,D . H . Kim,C . P . Hong ) 한국열처리공학회 1998 熱處理工學會誌 Vol.11 No.1

The softening behavior of squeeze cast Mg-Li-Al and Mg-Li-Al-Zr alloys have been investigated. The highest hardness values of Mg-Li-Al and Mg-Li-Al-Zr alloys were obtained after solution treatment at 400℃ for 1 hour. The hardness value, however, decreased as the aging temperature and time increased. Microstructural and calorometric analyses showed that quenched-microstructure changed from primary (α and β)+secondary α to primary(α and β)+secondary α+θ after aging. The softening during aging was due to the coarsening of θ precipitates.

컴퓨터 정보검색(情報檢索) 네트웍 - 호주편(豪洲篇) -

김영우,Kim, Yeong-U 한국과학기술정보연구원 과학기술정보센터 1979 Journal of Information Science Theory and Practice Vol.12 No.1

사상체질진단(四象體質診斷)의 객관화(客觀化)에 관한 연구(硏究)(기존(旣存) 설문지(說問紙)의 분석(分析)을 중심(中心)으로)

김영우,김종원,Kim, Young-woo,Kim, Jong-won 사상체질의학회 1999 사상체질의학회지 Vol.11 No.2

사상체질진단(四象體質診斷)에 있어 임상적(臨床的)으로 가장 많이 활용(活用)되며 또한 객관성(客觀性)이 인정(認定)되고 있는 방법(方法)으로는 설문지(設問紙)를 이용하는 방법(方法)이 있으며 그 중 대표적으로 사상변증내용(四象辨證內容) 설문조사지(設問調査紙)(I)과 사상체질분류조사지(四象體質分類調査紙)(QSCC II)가 있으나, 그 체질판정(體質判定)에 있어 각기 한쪽 체질(體質)로 치우치는 경향성(傾向性)을 보이므로 인(因)하여 임상가(臨床家)에서는 그 나름대로의 가치(價値)를 지니면서도 크게 일반화(一般化)되지 못하는 것이 현실(現實)이다. 본(本) 연구(硏究)는 사상체질진단(四象體質診斷)의 객관화(客觀化)를 위한 설문지(設問紙)의 연구(硏究)로써 동의대학교(東義大學校) 한의과대학(韓醫科大學) 부속한방병원(附屬韓方病院)에 내원(來院)한 자(者) 692명(名)(종합건강진단센터 대상자(對象者) 575명(名)과 환자(患者) 117명(名) 중 설문지(設問紙)(I)과 설문지(設問紙)(II)의 설문조사(設問調査) 결과(結果)와 사상체질전공의(四象體質專攻醫)의 체질판별(體質判別) 결과(結果)가 모두 치(致)하는 250명(名) 중(中)에서 설문지(設問紙) 내용(內容)이 비교적(比較的) 충실(充實)한 200명(名)을 대상(對象)으로 설문조사(設問調査) 내용(內容)을 통계분석(統計分析)하고 이를 토대(土臺)로 새로운 설문(設問)의 구성(構成)을 시도(試圖)하여 다음과 같은 결과(結果)를 얻게 되었다. 1. 설문지(設問紙)(I), 설문지(設問紙)(II)의 총(總) 192문항(問項)((설문지(設問紙)(I) 71문항(問項), 설문지(設問紙)(II) 121문항(問項))중에서 유의성(有意性)을 가지는 문항(問項)(P값이 최소(最小) 0.04 이상(以下))은 84문항(問項)(설문지(設問紙)(I)이 39문항(問項), 설문지(設問紙)(II)가 45문항(問項))이었다. 이중에서 서로 중복되는 항목(項目)이 22항목(項目)을 감안하연 설문지(設問紙)(I)과 설문지(設問紙)(II)의 총(總) 192문항(問項) 중(中) 체질(體質)에 따른 유의도(有意度) 검사(檢査)에 있어서 실질적(實質的)으로 유의(有意)있게 나타나는 문항(問項)은 총(總) 73문항(問項)이었다. P값이 0.001이하(以下)의 값을 보인 문항(問項)은 설문지(設問紙)(I)이 33문항(問項)이었으며, 설문지(設問紙)(II)의는 40문항(問項)으로 나타나 대체로 유의성(有意性)이 매우 높음을 알 수 있었다. 2. "설문지(設問紙)를 통한 사상체질(四象體質)의 임상적(臨床的) 분류방안(分類方案) 연구(硏究)"와 "체질진단분류(體質診斷分類)에 따른 질병(疾病) 및 증상유형(症狀類型)에 관한 임상적(臨床的) 연구(硏究)II"에서 유의성(有意性)이 입증(立證)된 설문문항(設問問項)을 몇 가지 추가(追加)하여 총(總) 851문항(問項)의 설문지(設問紙)를 구성(構成)하였다. 각(各) 문항(問項)들을 항목별(項目別)로 나누어 살펴보면, <체격(體格)과 체형(體型)>을 묻는 문항(問項)이 7개(個) 문항(問項)이었고, <외모(外貌)(안색(顔色))와 태도(態度)>를 묻는 문항(問項)이 7개(個) 문항(問項)이었고, <습관(習慣)과 성격(性格)>을 묻는 문항(問項)이 3개(個) 문항(問項)이었고, <생리(生理)-병리상태(病理狀態)>를 묻는 문항(問項)이 3개(個) 문항(問項)이었고, <평소(平素) 건강(健康)할 때 자주 느끼는 증상(症狀)>을 묻는 문항(問項)이 4개(個) 문항(問項)이었고, <식사습관(食事習慣)>을 묻는 문항(問項)이 3개(個) 문항(問項)이었으며, <평소(平素) 잘 나타나는 증세(症勢)>를 묻는 문항(問項)이 14개(個) 문항(問 The object of this study was 200 patients who had been treated in the Oriental Medical Hospital at Dong Eui Medical Center during 9 months from Jan. 1999 to sept. 1999. We proceeded the judgment of Sasang Constitution according to 'Questionnaire of Sasang Constitution Classification (I)', and 'Questionnaire of Sasang Constitution Classification II(QSCCII)' and the diagnosis by a medical specialist. The following conclusion were made in comparison with Sasang Constitution and Questionnaire. 1. We selected the 84 subjects what had the statistical value out of the 196 subjects('Questionnaire of Sasang Constitution Classification (I)' had the 71 subjects and 'Questionnaire of Sasang Constitution Classification II(QSCCII)', had the 121 subjects). And we selected again the 73 subjects('Questionnaire of Sasang Constitution Classification (I)', had the 33 subjects and 'Questionnaire of Sasang Constitution Classification II (QSCC II)' had the 40 subjects) out of the 84 subjects, because it had a repeated subjects. 2. We made the Questionnaire what has the 85 subjects, including the subjects what was approved its statistical value by 'A CLINICAL STUDY OF THE JUDGMENT OF SASANG CONSTITUTION ACCORDING TO QUESTIONNAIRE' and 'A CLINICAL STUDY OF THE TYPE OF DISEASE AND SYMPTOM ACCORDING TO SASANG CONSTITUTION CLASSIFICATION'. The subject what ask the physique and the body form was 7, the subject what ask the external appearance and the posture was 7, the subject what ask the habit and the character was 3, the subject what ask the physiology and the pathology was 3, the subject what ask the phenomenon that he has frequency was 4, the subject what ask the eating was 3, the subject what ask the symptom that he has frequency was 14, the subject what ask the work and the qualities-defects was 6, the subject what ask the friendly intercourse was 7, the subject what ask the usual mind was 5, the subject what ask the emotional inclination was I, the subject what ask the behavioral inclination was 10, the subject what ask the character was 15. 3. In the new Questionnaire, the subject what has relevance to Soyang was 84, the subject what has relevance to Soeum was 87, the subject what has relevance to Taeeum was 70. And we made the point of subject with the statistical ratio. The total point of Soyang was 7785.04, the total point of Soeum was 7742.80, the total point of Taeeum was 7746.60. 4. As a result of judgment of Sasang Constitution between the clinical diagnosis by a medical specialist and the new Questionnaire, the diagnostic accuracy of new Questionnaire was 73.33%. The diagnostic accuracy of Soyang was low, the others was high. And the Taeyang was excepted.

연접개발제한 폐지 이후 개발행위허가 심의제도 개선방안

김영우,윤정중,Kim, Young-Woo,Yoon, Jeong-Joong 한국토지주택공사 토지주택연구원 2012 LHI journal of land, housing, and urban affairs Vol.3 No.2

기반시설이 부족한 녹지지역 및 관리지역 농림지역 자연환경보전지역에서 난개발을 방지하고 환경을 보호하기 위하여 도입된 연접개발제한 제도는 이들 지역의 난개발 방지에는 기여하였지만 연접개발여부의 판단이 모호하고 소규모의 분산개발을 초래하거나 개발행위허가를 피해 산지전용허가를 통한 개발행위가 야기되는 등의 문제가 유발되어 폐지되기에 이르렀다. 그러나 난개발 방지를 위해 도시계획위원회의 심의를 받도록 하고 있으나 여전히 위원구성이나 재량권 남용 등의 문제를 안고 있으며, 녹지축 보전대책의 미흡, 공간정보체계의 활용 부족, 법률별 경관관리기준의 불일치, 그리고 물리적 환경규제의 획일화 등 여러 가지 문제들이 나타나고 있다. 따라서 심의제도 운영을 위한 개선방안으로, 도시계획위원회의 구성 및 기능재편과 전문분야 집중심의제 도입, 동일 녹지축 상의 지자체들의 경우 개발행위허가 통합조정위원회를 두어 녹지축 보전방안과 개발행위허가기준 마련, 도시계획정보시스템의 조기구축 및 활용, 개발행위허가 경관관리기준을 지역 실정에 맞게 세부적으로 구축, 개발행위허가 시 재량행위 최소화를 위해 경사도, 표고, 임목본수도 이외에 생태자연도와 국토환경성평가지도 등을 추가하여 개발행위허가 판단의 기초자료로 활용하는 방안 등을 제안하였다. The regulation of continuous and adjacent development was introduced to prevent unplanned and improper development and to protect environment in green zone and non-urban area that was deficient in infrastructure. Though it has been effective, it was repealed in 2011 by disorderly development problem caused by crafty tricks around restrictions. Alternatively, the Urban Planning Commission is now deliberating on the development permit, but there are still much to be resolved such as improper committee formation and abuse of power, insufficient green corridor preservation, a lack of use of planning information system, discordance between landscape management guidelines in laws, etc. Therefore, we suggest several ideas for improvement of development permit system as follows; intensive deliberation system in the Urban Planning Commission, integrated commission for green corridor prevention, early establishment of urban planning information system, making a development permission guideline to minimize discretional act of the Urban Planning Commission, etc.