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      • KCI등재

        설진(舌診)의 임상활용에 관한 연구

        김빛나라 ( Bin Na Ra Kim ),오민석 ( Min Seok Oh ) 한방재활의학과학회 2013 한방재활의학과학회지 Vol.23 No.3

        ObjectivesThis study was designed to: (1) investigate the clinical feature of tongue diagnosis, (2) make an observation of significant changes in tongue diagnosis according to the patient`s physical condition and laboratory result and (3) identify clinical efficacy of tongue diagnosis. Methods300 patients` tongue diagnosis results were analyzed and the patients were divided to each group according to the physical condition and laboratory result. Then, chi-square test was performed to assess statistical significance between tongue diagnosis results of each group. ResultsAs a result of analyzing the spread of tongue diagnosis according to the patient`s physical condition and laboratory result, 18 groups had statistical significance related to specific tongue color and tongue coating. ConclusionsEven if there would be possible misinterpretations in one-to-one match between the tongue diagnosis and certain diseases, we identified that tongue diagnosis results were changed somewhat related to patient`s physical condition with some tendency and tongue diagnosis could be used for meaningful clinical diagnostic tool. (J Korean Med Rehab 2013;23(3):149-157)

      • KCI등재후보

        경추 및 요추의 통증에 사용되는 견인요법에 대한 문헌 고찰

        이치호,김빛나라,정훈,이현재,이옥진,이은정,오민석,Lee, Chi-Ho,Kim, Bin-Na-Ra,Jung, Hun,Lee, Hyun-Jae,Lee, Ok-Jin,Lee, Eun-Jung,Oh, Min-Seok 척추신경추나의학회 2014 척추신경추나의학회지 Vol.9 No.2

        Objectives : This study aims to evaluate domestic/foreign clinical studies related to the traction therapy and analyse points to consider about cervical/lumbar traction therapy. Methods : Seven databases were searched for related articles about cervical/lumbar traction therapy from 1950 to 2014. Fourteen clinical studies and several systemic reviews were included among 144 studies searched. Out of fourteen clinical studies, four were case series and ten were controlled trials. Results : Most of included studies reported favorable effects of traction group compared to baseline of controlled group. The various mechanical factors most relevant to traction are 1) angle of pull and direction, 2) traction force, 3) duration of traction and frequency of treatment. Conclusions : We found various mistake in the applications of statistical methodologies of traction therapy targeting patients of cervical, lumbar vertebral disease. It is necessary for more randomized controlled trials to evaluate effect of cervical/lumbar traction therapy targeting patients of cervical, lumbar vertebral disease.

      • KCI등재

        십전대보탕가미방(十全大補湯加味方)의 창상(創傷) 치유(治癒) 효과(效果)

        정훈 ( Hoon Jung ),이현재 ( Hyun Jae Lee ),김빛나라 ( Bin Na Ra Kim ),이치호 ( Chi Ho Lee ),이은정 ( Eun Jung Lee ),허동석 ( Dong Seok Heo ),오민석 ( Min Seok Oh ) 한방재활의학과학회 2014 한방재활의학과학회지 Vol.24 No.3

        Objectives This study was aimed to investigate the effects of Sibjeondaebotanggamibang (SJT) on the wound-induced rats. Methods <In vitro> It was observed the effects of anti-oxidation and anti-inflammation by using of lipopolysaccharide (LPS)-treated RAW 264.7 cells. For the observing on SJT anti-oxidation, it needed to mesure the total amount of polyphenol, DPPH scavenging ability, ABTS scavenging ability and the value of ROS production. In order to observe on the anti-inflammation of SJT, it was mesured the value of No and Cytokine (TNF-α, IL-1β, IL-6). <In vivo> It needed to make a scar (around 2x2 cm2) on the top of the fascia in the back of the rats and then the rats were divided into 4 groups (n=6). Control group was not treated at all, whereas SJ group was orally medicated SJT, Terra group was percutaneously applied Terramycin, and SJ+Terra group was both orally medicated SJT and percutaneously applied Terramycin per day for three weeks. The size of wound was measured with Digimatic Caliper and the blood samples (WBC, neutrophil, monocyte, lymphocyte) were analyzed using Minos-ST, which were collected by cardiac puncture. The effect on inflammatory cytokine (TNF-α, IL-1β, IL-6), immunological cells in synovial fluid was measured. To measure the wound factor expressed by wounded skin sample, we extracted RNA and to investigate MMP-1,2,9 we used RT-PCR. For performing histopathological examinations, we paralyzed the rats by ether, and extracted wounded skin tissues, which were measured by H & E, and monitored on the optical microscope. Results <In vitro> 1. DPPH and ABTS scavenging activity of SJT was increased concentration- dependantly, and ROS scavenging activity was significantly increased (10, 100 μg/ ml). 2. NO production was significantly reduced in SJT treated cells (100 μg/ml), both TNF-α and IL-6 in SJT treated cells (1, 10, 100 μg/ml), and IL-1β in SJT treated cells (1, 100 μg/ml). <In vivo> 1. The size of wound was significantly decreasing in SJ group, Terra group, SJ+Terra group. 2. WBC was significantly reduced in SJ and SJ+Terra group, monocyte in SJ+Terra group. Neutrophil was also reduced in SJ, SJ+Terra group but meaningless. 3. TNF-α and IL-6 were significantly reduced in SJ group, Terra group, SJ+Terra group, and IL-1β in SJ+Terra group. 4. mRNA expression in MMP-1 was significantly reduced in SJ group. 5. Collegan production and chronic inflammation were significantly decreased in SJ group, Terra group, SJ+Terra groups. Re-epithelization on the skin in Terra group, SJ+Terra groups was decreased. Conclusions According to this in vitro experiment, Sibjeondaebotanggamibang (SJT) has the effects of anti-oxidative and anti-inflammatory. By in vivo experiment, SJT has the effects of anti-inflammatory. Moreover, the progress of recovery was found visually, heamatologically, genetically and histopathologically. In conclusion, it could be thought that SJT has effect on the treating of wound. (J Korean Med Rehab 2014;24(3):51-69)

      • KCI등재

        교통사고 후 발생한 경항통 환자에 대한 황련해독탕약침과 분리정제봉약침의 치료 효과 비교연구: 무작위 배정

        이옥진 ( Yu Chen Lee ),남대진 ( Dae Jin Nam ),허건 ( Gun Huh ),이재은 ( Jae Eun Lee ),김빛나라 ( Bin Na Ra Kim ),송은모 ( Eun Mo Song ),이은정 ( Eun Jung Lee ),이정민 ( Jung Min Lee ),오민석 ( Min Seok Oh ) 한방재활의학과학회 2014 한방재활의학과학회지 Vol.24 No.4

        ObjectivesThe purpose of this study is to compare the effects of HWANGRY-UNHAEDOKTANG Pharmacopuncture and Essential Bee Venom pharmacopuncture on cervical pain caused by traffic accident.MethodsThe clincal study was conducted to traffic accident patients who had admitted to Dae-Jeon University Cheonan Oriental Hospital from May 17, 2014 to September 2, 2014. The patients were simple randomization and divided into two groups. In one group, patients were treated with the oriental medicine and HWANGRYUNHAEDOKTANGPharmacopuncture, While in the other group, patients were treated with the oriental medi-cine therapy and Essential Bee Venom pharmacopuncture therapy. visual analogue scale (VAS), pain threshold and neck disablity index (NDI) were used To estimate the efficacy of Pharmacopuncture treatment.Results1) HWANGRYUNHAEDOKTANG Pharmacopuncture Group showed significant decrease of VAS and NDI after 3rd times treatment than before treatment (p<0.001). Essential Bee Venom Pharmacopuncture showed significant decrease of VAS, NDI and improve ment of pain threshold after 3rd times treatment than before treatment (p<0.01, p<0.001). 2) There was no significant difference between HWANGRYUNHAEDOKTANGPharmacopuncture group and Essential Bee Venom Pharmacopuncture group in VAS, pain threshold and NDI. ConclusionsWe found out that HWANGRYUNHAEDOKTANG Pharmacopuncture and Essential Bee Venom Pharmacopuncture treatment are considered to be effective and useful in cervical pain caused by traffic accident. (J Korean Med Rehab 2014;24(4): 145-153)

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