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김수경,김은화,이혜경,김병구,백현선,조덕수,최용우,이용웅 대한소화기내시경학회 1996 Clinical Endoscopy Vol.16 No.6
Colorectal cancer consists of 8.2 percent of all malignancy in korea, and shows more increaing tendency. Despite the advances in the detection of calorectal cancer no single screening technique has achieved both high degree of diagnostic accuracy and minimal patient morbidity. We studied 24 patients, who underwent colonoscopy, with clinical suspicious colon cancer at Presbyterian Medical Center between Jan and Sep.1995, and evaluated the diagnostic feasibility of colon lavage cytology using oral cleansing solution. The results were as follows; 1) Colorectal cancer(adenocarcinoma) was detected in 19 of 24 cases by colonoscopic biopsy and only one patient who 'was not approached to the lesion site because of abdominal pain during colonoscopy, was detected colon cancer by explo-laparotomy. 2) In the 20 cases of colorectal cancer, colon lavage cytology revealed dysplastic cells in 1 case, and adenocarcinoma cells in 6 cases, so, the sensitivity of colon lavage cytology is 35 percent. 3) The location of the cancer was follow:Five ascending colon, two transverse colon, five sigmoid colon, and eight rectum and the 7 cases showing positive colon lavage cytology was fallow: two ascending colon, one transverse colon, one sigmoid colon, three rectum. 4) The colectomy was performed in the 17 cases(Dukes' B: five, C: twelve). The Dukes' classification of the 7 case showing positive colon lavage cytology is two in Dukes' B, four in Dukes' C, and one in Dukes' D. In conclusion, we think the cytologic study of colon lavage fluid might be considered as one of the noninvasive diagnostic tools in colorectal cancer, if it's sensitivity improved, epecially, incomplete retrograde cecal intubation, or refusal colonoscopy, and ulcerative colitis combined with colon cancer.