판례연구보고

김범희,Kim, Beom-Hui 한국발명진흥회 2005 發明特許 Vol.30 No.10

아니사키스로 인해 발병한 장폐색

김범희 ( Beom Hee Kim ),박희욱 ( Hee Ug Park ),박승근 ( Seung Keun Park ),전승민 ( Soung-min Jeon ),정찬우 ( Chan Woo Jung ),손창목 ( Chang Mok Son ),최현욱 ( Hyun Wook Choi ),김혜숙 ( Hye Sook Kim ) 대한소화기학회 2018 대한소화기학회지 Vol.72 No.1

Human anisakiasis is a disease caused by an infestation of the third stage larvae of family anisakidae. The ingested larvae invade the gastrointestinal wall, causing clinical symptoms that include abdomen pain, nausea, and vomiting. Although enteric anisakiasis is extremely rare, it can induce intestinal obstruction. We report a case in which emergency surgery was needed due to intestinal obstruction that coincided with symptoms related to anisakiasis, along with a brief literature review. (Korean J Gastroenterol 2018;72:33-36)

초치료 만성 B형간염 환자에서 엔테카비어의 장기 치료 효과 및 그 예측인자

김범희 ( Beom Hee Kim ),윤범용 ( Beom Yong Yoon ),박대화 ( Dae Wha Park ),이엄석 ( Eaum Seok Lee ),김석현 ( Seok Hyun Kim ),이병석 ( Byung Seok Lee ),이헌영 ( Heon Young Lee ) 대한내과학회 2010 대한내과학회지 Vol.85 No.2

목적: 초치료 만성 B형간염 환자들에서 엔테카비어의 치료 효과와 그 예측인자에 대해 분석하였다. 방법: 2007년 3월부터 2011년 5월까지 과거 항바이러스제 치료 경험이 없는 만성 B형간염 환자로서 엔테카비어 0.5 mg을 매일 최소 48주 이상 복용한 환자 77명을 후향적으로 조사하였다. 엔테카비어 투여 중 혈청 HBV DNA치가 116 copies/mL 이하로 감소하여 검출되지 않는 경우인 바이러스 반응과 혈청 ALT치의 정상화되는 경우인 생화학적 반응, HBeAg의 혈청 소실과 혈청전환을 각각 평가하였다. 결과: 치료 12, 24, 48, 96, 144주에 대한 누적 바이러스 반응률은 각각 59.7%, 82%, 88.3%, 89.6%, 93.1%였다; 누적 생화학적 반응률은 각각 51.9%, 74%, 84.4%, 94.8%, 98.3%였다; HBeAg의 누적 혈청 소실률은 10.5%, 18.4%, 28.9%, 36.8, 47.4%였다; 누적 HBeAg 혈청 전환율은 7.9%, 18.4%, 21.1%, 28.9%, 39.5%였다. 다변량 분석을 시행한 결과 혈청 HBV DNA 음전과 관련된 독립적 예측인자는 기저 HBeAg 음성(p = 0.006)과 치료 12주 후 바이러스 반응인 초기 바이러스 반응(p = 0.027)이었다. 또한 HBeAg 혈청 소실과 관련된 독립적 예측인자도 초기 바이러스 반응(p = 0.001)이었다. 결론: 엔테카비어는 초치료 만성 B형간염 환자에서 뛰어난 생화학적 반응과 바이러스 반응을 보였다. 초기 바이러스 반응은 혈청 HBV DNA 음전과 HBeAg 혈청 소실을 예측할 수 있는 독립적 인자로 확인되어 치료 중 초기 바이러스 반응이 엔테카비어의 장기적인 치료 반응을 예측하는 데 유용할 것으로 생각된다. Background/Aims: The aims of this study were to characterize the treatment response to entecavir and to examine factors affecting that response. Methods: A total of 77 nucleoside-na?ve patients with chronic hepatitis B who had received entecavir (0.5 mg daily) for at least 48 weeks were consecutively enrolled between March 2007 and March 2011. The rates of virological response (hepatitis B virus [HBV] DNA < 116 copies/mL), biochemical response (alanine aminotransferase ≤ upper limit of normal), hepatitis B e antigen (HBeAg) loss, and seroconversion were retrospectively analyzed. Results: The cumulative rates of virological response at 12, 24, 48, 96, and 144 weeks were 59.7%, 82%, 88.3%, 89.6%, and 93.1%, respectively; biochemical response rates were 51.9%, 74%, 84.4%, 94.8%, and 98.3%, respectively; HBeAg loss rates were 10.5%, 18.4%, 28.9%, 36.8%, and 47.4%, respectively; and HBeAg seroconversion rates were 7.9%, 18.4%, 21.1%, 28.9%, and 39.5%, respectively. In multivariate analysis, independent predictors associated with HBV DNA polymerase chain reaction (PCR) negativity were the absence of HBeAg at baseline (p = 0.006) and early virological response (HBV DNA < 2,000 copies/mL after 12 weeks of therapy; p = 0.027). In univariate analysis, early virological response was an independent factor predicting HBeAg loss (p = 0.001). Conclusions: Entecavir induced excellent biochemical and virological responses in nucleoside-na?ve patients with chronic hepatitis B. Early virological response was an independent factor predicting HBV PCR negativity and HBeAg loss, and can be used to predict long-term treatment response to entecavir. (Korean J Med 2013;85:157-166)

제주지역 초등학생의 체격과 신체조성에 대한 연구

김범희(Bum Hee Kim),최태희(Tae Hee Choi) 한국체육교육학회 2013 한국체육교육학회지 Vol.18 No.3

본 연구는 제주지역 초등학교 2, 4, 6학년 578명(1998년 321명, 2010년 257명))을 대상으로 1998년 학생들과 2010년 학생들의 12년 사이의 체격과 신체조성의 변화를 비교하기 위하여 평균, 표준편차, 독립표본 t검정을 실시한 결과 다음과 같은 결론을 얻었다. 신장, 체중, 상완위, 하퇴위는 각각 남학생 6학년과 여학생 4학년에서 2010년 학생들이 1998년 학생들 보다 유의하게 증가하였고, 상완골단폭과 대퇴골단폭은 남학생과 여학생 2, 4, 6학년 모두 2010년 학생들이 1998년 학생 보다 유의하게 감소하였고, %Fat는 남학생 6학년에서 2010년의 학생들이 1998년 학생들 보다 유의하게 증가하였으며, 여학생 6학년은 유의한감소를 나타냈다. Fat는 남학생 6학년의 2010년 학생들이 1998년 학생들 보다 유의하게 증가하였으며, FFW는 남학생 6학년, 여학생 4학년과 6학년이 유의하게 증가하는 것으로 나타났다. This study has reached a following conclusion from comparison analysis of 578(2nd, 4th, 6th grade) students` physique and body composition in Jeju from 1998(321 students) to 2010(257 students). ``Height``, ``weight``, ``biceps girth`` and ``calf girth`` have meaningfully growth in 6th grade male students and 4th grade female students. ``humerus diameter`` and ``femur diameter`` have meaningfully decreased in every grade students for both genders. ``%Fat`` has meaningfully growth in 6th grade male students but decreased in female students of same grade. ``Fat`` has meaningfully growth in 6th grade male students. ``FFW`` has meaningfully growth in both gender of 6th grade students and 4th grade of female students.

초등학교 고학년 학생의 체형 및 신체구성의 특성

김범희(Bum Hee Kim) 한국발육발달학회 1996 한국발육발달학회지 Vol.4 No.1

For the study on the characteristics and correlations of the somatotype and body composition of the elementary school boys and girls, the 10 items of the physical features for 265 children ranged from the 5th grade of 10 years to the 6th grade 11 years of the B elementary school located at Cheju City are measured on the base Heath-Cater method and the somatotype elements and changes in the body compositions of theirs are analyzed according to their grade and sex. The results are summarized as th following: 1. In of the sexual distinction of the physique, the female is higher and heavier than the male by 2.25㎝ and 0.94㎏ but the upper arm, humerus, and femur of his are longer than those of hers by 1.12 ㎝, 0.31㎝, and 0.40㎝ respectively. 2. In the sexual difference of the body composition, the skinfold thickness in triceps of his the thicker than that of hers but the skin folds of the suprailiac and calf do not have considerable difference between them. 3. In the distribution of the physique of the males and femmes, the Physique of the boys in the 5th and 6th grade belong to C, G, D and E. somatotype, the girls belong to M, C, I somatotype. 4. The somatotype of the boys in the 5th and 6th grade are 4.07-4.67-2.53 and 3.50-4.41-2.78, and those of the girls in the same grades are 3.96-3.86-2.83 and 3.63-3.37-3.05 respectively. 5. In the distribution of the somatotype according to the physique and the body composition, for the weight of the boys, the B type are the heaviest, followed by the D and C type in turn. However, G, M, and type are light. For the % fat and fat of the boys, the B type of 30.64% and 15.5㎏ is the highest among the other type, but M, E, and G type are low. For the FFM of the boys, the D type of 40.13㎏ is the heaviest, but the but M, E, and G type are light. For the girls, the B type of 50.91㎏ is the heaviest, followed by the C, M, and H type in turn. The B type of 23.90% and 12.27㎏ is the heaviest for the %fat and fat of hers, and the C type of 31.18㎏ is the heaviest for the FFM. 6. The mean somatotypes are 3.79-4.54-2.65 for boys and 3.79-3.60-2.94 for the girls, this shows that the considerable sexual distinction results from only the mesomorphic components. 7. The height correlates highly with the weight and the FFM, and the weight relates positively th the endomorphic and the mesomorphic comprnents but negatively to the ectomorphic component. Also, the weight correlates highly to the body composition. The fat relates positively to the endomorphic and the mesomorphic components but negatively to the ectomorphic component.

제주시 지역과 중국 요녕성 초등학생의 체격과 신체조성에 대한 연구

김범희(Kim, Bum-hee),최태희(Choi, Tae-Hee),金成吉(Jin Cheng-ji) 한국체육교육학회 2014 한국체육교육학회지 Vol.19 No.2

본 연구는 제주시 지역 J초등학교 학생 257명(2학년 85명, 4학년 87명, 6학년 85명), 중국 요녕성 대련시 M 초등학교 315명(2학년 106명명, 4학년 101명, 6학년 108명) 총 572명을 대상으로 한국과 중국 초등학생의 체격과 신체조성의 변화를 비교 분석한 결과 다음과 같은 결론을 얻었다. 체격의 비교에서 남학생은 신장, 체중, 하퇴위, 상완골단폭, 대퇴골단폭에서 2, 4, 6학년 모두 중국이 한국 보다 높게 나타났으며, 상완위는 한국이 중국 보다 높게 나타났다, 여학생은 2학년에서 신장, 체중, 상완위, 하퇴위, 상완골단폭, 대퇴골단폭 등 모두 중국이 한국 보다 높게 나타났으며, 4학년은 체중, 위육, 폭육은 한국이 높게 나타났고, 6학년은 신장, 체중, 하퇴위, 대퇴골단폭에서 중국이 높게 나타났다. 신체조성 비교에서 남학생은 상완배부, 견갑하연부, 장골능상부, 하퇴배부, %FAT, FAT, FFW에서 2, 4, 6학년 모두 중국이 한국 보다 높게 나타났고, 여학생은 견갑하연부, 장골능상부, 하퇴배부, %FAT, FAT에서 모두 중국이 한국 보다 높게 나타났다. The purpose of this study was to compare the physique and body composition of Korean and Chinese elementary school students. 257(87 students of 2nd grade, 87 students of 4th grade, 85 students of 6th grade) students from Jeju, South Korea and 325(106 students of 2nd grade, 101 students of 4th grade, 108 students of 6th grade) students from Liaoning, China were compared.. The study has reached the following conclusion using average, standard deviation, independent sample t-test. In the comparison of physique, Chinese male students" height, weight, calf girth, humerus diameter, femur diameter are higher than Korean students in every comparison grade(2nd, 4th and 6th grade). Chinese 2nd grade female students" height, weight, biceps girth, calf girth, humerus diameter, femur diameter are higher than Korean 2nd grade female students. Korean 4th grade female students" weight, girth, diameter are higher than Chinese 4th grade female students. Chinese 6th grade female students" height, weight, calf girth, femur diameter are higher than Korean 6th grade female students. In the comparison of body composition, Chinese male students" triceps skinfold, subscapular skinfold, subscapular skinfold, calf skinfold, %FAT, FAT, FFW are higher than Korean students in every comparison grade(2nd, 4th and 6th grade). Chinese female students, subscapular skinfold, suprailiac skinfold, triceps skinfold, %FAT, FAT are higher than Korean female students.

초등학생의 신체적 특성과 체력요인의 관련성

김범희(Bum Hee Kim) 한국체육교육학회 2000 한국체육교육학회지 Vol.4 No.2

The purpose of this study was to provide guidelines for directing the growth and development of elementazy school students by analyzing the characteristics of and the relationships between physique, body composition, somatotype, and physical fitness of elementary school students. In the study, 1,281 children ranging in age from 6 to 11 (649 boys and 632 girls) participated as subjects. The characteristics of physique, body composition, and somatotype were analyzed two-way ANOVA (age x gender), and the relations of age, gender, body composition, and somatotype with physical fitness were analyzed by multiple regressions. Results of the study were as the following: 1. Characteristics of physique The height was not influenced by gender boys showed higher values than girls in body weight, All of the measured items displayed an increase with age in both boys and girls. 2. Characteristics of body composition Boys were higher than girls in body density and fat weight. While body density decreased with age, percent fat, fat weight, and FFM increased in both boys and girls. 3. Somatotype Boys showed higher distribution near the mesomorphic type, indicating that they were better developed in bone and muscle, whereas girls were distributed toward endomorphic type, indicating that they were high in percent fat. 4. Physical fitness The effect of gender was significant for all test items. While boys were better than girls in muscular strength, power, muscular endurance, and agility, girls were better than boys in flexibility and balance. Age was shown to affect all test items except flexibility. Muscular strength, power, muscular endurance, balance, and agility were shown to increase with age. 5. Relationships between body composition, somatotype, and physical fitness Gender, age, and ectomorphic component contributed significantly to all of the components of physical fitness. Percent fat and mesomorphic component contributed significantly to musclular strength, muscular endurance, agility, and balance, while endomorphic component contributed only to muscular strength. These results indicate that the characteristics of physique, body composition, and somatotype are highly influenced by gender and age. Results of multiple regression suggest that body composition and somatotype are important factors determining the levels of physical fitness in elementary school students.

한국과 오스트레일리아 초등체육과 교육과정 비교

김범희(Bum Hee Kim) 한국체육교육학회 2011 한국체육교육학회지 Vol.16 No.4

이 연구는 2007년에 개정된 한국초등체육교육과정과 2008년에 개정된 호주 빅토리아주의 초등체육교육과정을 비교 분석한 결과 다음과 같은 결론을 얻었다. 첫째, 교육과정의 내용을 담는 체제는 비슷하나 한국은 교과서 및 교사용지도서가 있으나 호주는 교사들의 수업 매뉴얼이 교육과정에 제시되어 있다는 점에서 큰 차이점이 있었다. 또한, 한국은 신체활동 가치중심의 개인의미모형이고 호주 빅토리아주는 기본 운동기술 중심의 발달모형 중심의 교육과정이였다. 둘째, 한국은 신체활동 가치를 중심으로 하는 개인의미 중심의 해석학적 철학을 배경으로 하고 있으나 호주는 학습자 발달단계 중심으로 하는 발달 중심의 진보주의 철학을 배경으로 하고 있었다. 셋째, 체육목적은 우리나라는 내재적 가치중심을 추구하고 있으나, 호주는 외재적 가치 중심의 목적을 제시하고 있었다. 넷째, 체육내용은 우리나라는 신체활동 가치 개념을 바탕으로 하는 가치 개념을 제시하고 있으나 호주 빅토리아주 교육과정은 저, 중, 고학년 별로 기본운동 중심 내용으로 제시하는 특징을 가지고 있었다. 다섯째, 수업방법 및 평가에서는 우리나라는 수업방법이 구체적으로 제시되지 않았고 호주에서는 매우 상세하게 제시되어 있다. This research reaches conclusions as below after comparing Korea elementary physical education curriculum and Victoria Australia Primary physical education curriculum. First, there is a big difference in the way how curriculum is implemented during the class. Korean curriculum has text books and teacher`s guide but in Australia, class manuals are reflected in the curriculum. Second, Korea curriculum comes from hermeneutical philosophy of personal meaning model focused on value of individual physical activity but curriculum in Victoria comes from progressive philosophy focused on developmental stage model based on basic activity skills. Third, Korean aims of physical education is internal value but Victoria physical education is aimed at external value. Fourth, the contents of education are different. Korea curriculum provides value of physical activities but Victoria`s curriculum provides basic activity skills divided by elementary, middle and high stage of grade. Fifth, regarding the way of teaching and evaluation, there is no detail guide line in Korean curriculum even though Australian curriculum provides detail teaching and evaluation method.

증례 : 소화기 ; 골수 전이를 동반한 삼중 조기위암 1예

김혜진 ( Hye Jin Kim ),김범희 ( Beom Hee Kim ),윤범용 ( Beom Yong Yoon ),탁대현 ( Dae Hyun Tak ),문희석 ( Hee Seok Moon ),성재규 ( Jae Kyu Sung ),정현용 ( Hyun Yong Jeong ) 대한내과학회 2013 대한내과학회지 Vol.84 No.1

최근 조기위암의 발견 빈도가 높아지고 치료 성적 또한 향상되어 현재 조기위암의 5년 생존율은 85% 이상으로 보고되고 있다. 그러나 조기위암으로 진단되었어도 림프절전이나 기타 타 장기로의 원격전이 가능성을 반드시 고려하여야 한다. 조기위암에서 원격전이는 대개 복막, 국소 림프절, 그리고 간에 주로 일어나며 골 전이는 매우 드물다. 최근 저자들은 삼중의 조기위암의 형태를 가진 반지세포암이 골수전이를 동반한 50세 남자 환자를 경험하였기에 문헌고찰과 함께 보고하는 바이다. The clinical outcome of early gastric cancer (EGC) has gradually been improving, and the 5-year survival rate for patients with EGC has been reported to exceed 85% in most studies. However, in some rare cases, EGC is associated with distant metastasis. Bone metastases from stomach cancer are usually osteolytic lesions. Although there have been a few reports of EGC with bone marrow metastasis, cases of triple EGC with bone marrow metastasis are rare. We report a 50-year-old male patient who was diagnosed with triple EGC with bone marrow metastasis. This case can be considered to be rare because the patient had no spread of the disease to other organs. (Korean J Med 2013;84:71-75)

초등학교 학생의 체형 및 신체구성의 특성

김상홍(Sang Hong Kim),김범희(Bum Hee Kim) 한국발육발달학회 1997 한국발육발달학회지 Vol.5 No.1

This study adopted Health-Carter`s method and measured ten body composition in 638 children at B Elementary School in Cheju City in order to classify their somatotype and to analyze their physical characteristics. The study analyzed changes of somatotype and body composition depending on age and sex. The results are summarized like the followings. 1. Structural Difference Between Sexes Although the structural difference between male and female children was not so great, the boys` values are higher in almost every body composition than the girls`. Only in girls in higher grades are found higher values of height, weight, and biceps girth than in boys. 2. Difference of Body Composition Between Sexes In the lower grades, the mean values of calf skinfold and FFM mass are higher in boys than in girls, whereas the mean values of triceps skinfold, subscapular skinfold, suprailiac skinfold, fat weight, and percent fat are higher in girls than in boys. In the middle grades, the mean values of triceps skinfold, subscapular skinfold, suprailiac skinfold, calf skinfold, fat weight, and FFM mass are higher in boys han in girls, whereas the mean values of percent fat are higher in girls than in boys. In the higher grades, the mean values of triceps skinfold, subscapular skinfold, suprailiac skinfold, and calf skinfold are higher in boys than in girls, whereas the mean values of percent fat, fat weight, and FFM mass are higher in girls than in boys. 3. Difference of Somatotype 1) Difference of Somatotype Between Sexes In the lower grades, the boys` somatotype is 2.96-4.83-1.84, whereas the girls` is 3.50-4.41-2.78. In the middle grades, the boys` somatotype is 3.71-4.77-1.97, whereas the girls` is 3.61-4.1902.16. In the higher grades, the boys` somatotype is 4.10-4.9101.97, whereas the girls` is 4.02-4.32-2.22. 2) Distribation of Body Types. Mesomorph is the most dominant type is every grade, endomorph the second, and ectomorph the third. Endomorph increases as the grade goes up, which is more evident in girls than in boys. 3) Correlation of Thirteen Somatotype Elements with Body types A and B are relatively high in endomorph. So are C, D, E, F, G, and M in mesomorph. However, there is a difference between sexes in ectomorph. H and I are high in boys, whereas H, I, J, and K are high in girls. 4) Distribution of Somatotype Elements The main types in lower grades are E and D in boys, and E, D, and C in girls; in middle grades E, D, and C in boys, and E, C, D, B in girls; in higher grades E, D, C, and B in boys, and B, C, E, and M in girls. 4. Correlation of Body Composition with Body types There is no statistically significant difference in correlation of body composition with body types between sexes. Weight, height, percent fat, fat weight, FFM mass normally correlate with endomorph and mesomorph, but there is counter-correlation between those body composition and ectomorph.