유방 부분 절제술 후 방사선 치료 시 TOMO Direct를 이용한 접선 조사의 선량적 유용성에 관한 고찰

김미정,김주호,김훈겸,조강철,전병철,조정희,Kim, Mi-Jung,Kim, Joo-Ho,Kim, Hun-Kyum,Cho, Kang-Chul,Chun, Byeong-Chul,Cho, Jeong-Hee 대한방사선치료학회 2011 대한방사선치료학회지 Vol.23 No.1

Purpose: Investigation of the clinical use of tangential fields technique using TOMO direct in comparison to conventional LINAC based radiation therapy after breast partial mastectomy. Materials and Methods: Treatment plans were created for 3 left-sided breast cancer patients who had radiation therapy after breast partial mastectomy by using wedged tangential fields technique, field in field technique (FIF), TOMO Direct, TOMO Direct intensity modulated radiation therapy (IMRT) under the normalized prescription condition ($D_{90%}$: 50.4 Gy/28 fx within CTV). Dose volume histogram (DVH) and isodose curve were used to evaluate the dose to the clinical target volume (CTV), organ at risk (OAR). We compared and analyzed dosimetric parameters of CTV and OAR. Dosimetric parameters of CTV are $D_{99}$, $D_{95}$, Dose homogeneity index (DHI: $D_{10}/D_{90}$) and $V_{105}$, $V_{110}$. And dosimetric parameters of OAR are $V_{10}$, $V_{20}$, $V_{30}$, $V_{40}$ of the heart and $V_{10}$, $V_{20}$, $V_{30}$ of left lung. Results: Dosimetric results of CTV, the average value of $D_{99}$, $D_{95}$ were $47.7{\pm}1.1Gy$, $49.4{\pm}0.1Gy$ from wedged tangential fields technique (W) and FIF (F) were $47.1{\pm}0.6Gy$, $49.2{\pm}0.4Gy$. And it was $49.2{\pm}0.4$ vs. $48.6{\pm}0.8Gy$, $49.9{\pm}0.4$ vs. $49.5{\pm}0.3Gy$ Gy for the TOMO Direct (D) and TOMO Direct IMRT (I). The average value of dose homogeneity index was W: $1.1{\pm}0.02$, F: $1.07{\pm}0.02$, D: $1.03{\pm}0.001$, I: $1.05{\pm}0.02$. When we compared the average value of $V_{105}$, $V_{110}$ using each technique, it was the highest as $34.6{\pm}9.3%$, $7.5{\pm}7.9%$ for wedged tangential fields technique and the value dropped for FIF as $16.5{\pm}14.8%$, $2.1{\pm}3.5%$, TOMO direct IMRT as $7.5{\pm}8.3%$, $0.1{\pm}0.1%$ and the TOMO direct showed the lowest values for both as 0%. Dosimetric results of OAR was no significant difference among each technique. Conclusion: TOMO direct provides improved target dose homogeneity over wedged tangential field technique. It is no increase the amount of normal tissue volumes receiving low doses, as oppose to IMRT or Helical TOMO IMRT. Also, it simply performs treatment plan procedure than FIF. TOMO Direct is a clinical useful technique for breast cancer patients after partial mastectomy.

재현의 곤경, 설득의 서사 넘기 ― 5월 광주 서사의 현재와 과제 ―

김미정 ( Kim¸ Mi-jung ) 현대문학이론학회 2020 現代文學理論硏究 Vol.0 No.83

오늘날 재현을 질문하는 과정 자체가 아이러니하게도, 백래쉬와 경합하는 장이 되기도 한다. 재현에 대한 문제의식이 궁극적으로 어떤 언설과 연결될지 가늠하는 것도 중요해졌다. 본 논문은, 오늘날 재현의 윤리에 대한 질문이, 대중적 백래쉬의 정동과 교착하는 장면들에 대한 문제의식에서 출발했다. 최근 빈번히 발견되는 설득의 서사구조에서도 이런 우려를 생각해볼 수 있다. 이러한 서사구조는 백래쉬와 부정의 언설 앞에서 스스로를 증명해야 하는 강박과 관련될 것이다. 그런데 그 설득의 과정 자체가 재현에 대한 오인을 발생시키곤 한다.. 오늘날 서사 속 5월 광주 재현이 처한 곤경도 이러한 재현 일반의 문제와 연동한다. 1990년대 이후 제도화, 공식화한 언어와 상상력을 공회전하면서 5월 광주 재현은 부정, 백래쉬 앞에서 무력해지곤 한다. 이것은 같은 언어를 공유, 활용하고 있는 조건과 장의 문제이기도 하다. 이 글은, 영화 <김군>(2018), 최윤 소설 「저기 소리 없이 한 점 꽃잎이 지고」(1988)를 재독해하면서 이러한 5월 광주 서사의 현재와 과제를 가늠하고자 했다. This study started with the problem of the scenes where the question about the ethics of representation today intersects with the affect of popular backlash. Ironically, the process of questioning representation itself becomes a field to compete with opposing forces. Therefore, it is also necessary to carefully assess what kind of discourse will ultimately lead to the problem about representation today. This concern can also be considered in the narrative structure of persuasion, which is frequently discovered recently. This narrative structure will be related to the intention to prove oneself in front of backlash and denial. However, the process of persuasion itself causes misconceptions about representation. In today's narrative, the predicament of the May Gwangju uprising representation is also linked to this problem. Since the 1990s, the institutionalized and formalized language and imagination have been lethargy. This is also a matter of foundation and field sharing the same language. This article attempted to assess the present and tasks of the May Gwangju uprising narrative by reading the movie < Kim-Gun > (2018) and Choi Yoon's novel(1988).

Pb(Mn_1/3Nb_2/3)O₃-PbZrO₃-PbTiO₃ 세라믹스의 압전특성에 미치는 Al₂O₃의 영향

김미정,김재창,김영민,어순철,김일호,Kim Mi-Jung,Kim Jae-Chang,Kim Young-Min,Ur Soon-Chul,Kim Il-Ho 한국재료학회 2005 한국재료학회지 Vol.15 No.7

Piezoelectric properties of $Pb(Mn_{1/3}Nb_{2/3})O_3-PbZrO_3-PbTiO_3$ ceramics were investigated with $Al_2O_3$ content $(0.0-1.0 wt\%)$. The constituent phases, microstructure, electromechanical coupling factor, dielectric constant, piezoelectric charge and voltage constants were analyzed. Diffraction peaks for (002) and (200) planes were identified by X-ray diffractometer for all the specimens doped with $Al_2O_3$, indicating the MPB (morphotropic phase boundary) composition of tetragonal structures. The highest sintered density of $7.8 g/cm^3$ was obtained for $0.2wt\%\;Al_2O_3-doped$ specimen. Grain size increased by doping $Al_2O_3$ up to $0.3 wt\%$, and it decreased by more doping. Electromechanical coupling factor, dielectric constant, piezoelectric charge and voltage constants increased by doping $Al_2O_3$ up to $0.2wt\%$, and it decreased by more doping. This might result from the formation of oxygen vacancies due to defects in $O^{2-}$ ion sites and the substitution of $Al^{3+}$ ions.

파종시기별 유효적산온도(GDD)가 옥수수의 생육 및 수량변화에 미치는 영향

김미정,정건호,김성국,이재은,전원태,심강보,김민태,우관식,권영업,허성기,Kim, Mi Jung,Jung, Gun Ho,Kim, Sung Kook,Lee, Jae Eun,Jeon, Weon Tai,Shim, Kang Bo,Kim, Min Tai,Woo, Koan Sik,Kwon, Yong Up,Heu, Sunggi 한국작물학회 2017 한국작물학회지 Vol.62 No.3

A total of 15 different corn hybrids, Kwangpyeongok, Gangdaok, Yanganok, Singwangok, Jangdaok, Cheonganok, Cheongdaok, Andaok, Dapyeongok, Pyeongkangok, Pyeonganok, Daanok, Sunwon 184, Gangilok, and P3394 was used to investigate the growth and yield depending on the sowing date. The sowing dates were April 5, June 25, and July 5 and each experiments was performed in triplicste. The growth of Gangdaok was the highest. However, although the growth of Kwangpyeongok, was lower thanthar of Gangdaok, its stem height to ear height ratio was lower than that of Gangdaok, thus, Kwangpyeongok may be more suitable for stable cultivation. Both growth and yield of Daanok were low, regardless of planting date, but yield and ear shape of Pyeongkangok and Dapyeongok were for fresh corn. Growth and yield of the 15 different corn hybrids varied depending on the planting date, However, the growth degree days (GDD) was the most important factor governing the maturity of corn. More than $1500^{\circ}C$ of GDD was sufficient to harvest mature corn hybrids in the central region of Korea. Besides yield and growth, other characteristics, such as sweetness and taste of the hybrids, should be investigated further the selection of the best corn hybrid.

AHP를 이용한 사서교사의 북큐레이션 서비스 제공에 대한 우선순위 분석

김미정,이병기,임정훈,Kim, Mi-Jung,Lee, Byeong-Kee,Lim, Jeong-Hoon 한국도서관정보학회 2020 한국도서관정보학회지 Vol.51 No.3

This study aims to identify priorities in book curation service that the teacher librarians perceive important through the AHP (Analytic Hierarchy Progress) method by comparing the jobs of teacher librarians with those of curators and selecting the contents and areas of book curation service provided by school libraries. For the purpose, this study categorized the book curation service areas by class and analyzed the priorities in the book curation service areas in the school libraries by applying the AHP method on the teacher librarians who are the personnel in school libraries. As a result, the priorities in the upper-tier class were turned out to be information services, improvement of expertise, information resources, management, and promotion & marketing in that order. The priorities in the lower-tier evaluation areas were shown in the order of survey & research, Q&A, self-development, exhibition, budget allocation, connecting with experts, trend analysis, reading education, human resources, planning, collaboration class, marketing services, book status, online promotion, offline promotion, and facilities & environment. Based on the results, this study suggested the following plans to provide effective book curation services in school libraries: grasping characteristics of school library users, setting classification criteria for book curation, and finding reader participation-oriented book curation service. 본 연구는 큐레이터와 사서교사의 직무를 상호 비교·분석하여 학교도서관에서 제공하는 북큐레이션 서비스의 내용과 영역을 설정한 후, AHP(Analytic Hierarchy Progress) 방법을 통해 사서교사가 중요하게 인식하는 북큐레이션 서비스의 우선순위를 밝히는 데 목적이 있다. 이를 위해 북큐레이션 서비스 영역을 계층별로 나누고, 학교도서관 전담인력인 사서교사들을 대상으로 AHP 방법을 적용하여 학교도서관 북큐레이션 서비스 영역의 우선순위를 분석하였다. 분석결과 상위계층의 우선순위는 정보서비스, 전문성 신장, 정보 자원, 경영, 홍보 및 마케팅 순으로 나타났고, 하위계층의 우선순위는 조사 및 연구, 질의응답, 자기계발, 전시, 예산편성, 전문가 연계, 트렌드 분석, 독서교육, 인적자원, 기획, 협력수업, 마케팅 서비스, 소장, 온라인 홍보, 오프라인 홍보, 시설 및 환경 순으로 나타났다. 이를 토대로 학교도서관 북큐레이션 서비스를 효과적으로 제공하기 위한 방안으로 학교도서관 이용자의 특성 파악, 북큐레이션을 위한 분류기준의 설정, 독자 참여형 북큐레이션 서비스 모색의 필요성을 제시하였다.

체험경제이론에 의한 북큐레이션 교육 프로그램이 지각된 가치와 지속적 참여 의도에 미치는 영향에 관한 연구

김미정,이병기,Kim, Mi-Jung,Lee, Byeong-Kee 한국도서관정보학회 2022 한국도서관정보학회지 Vol.53 No.3

By developing and implementing a book curation education program that reflects the experiential economy theory, this study aims to verify the effect that experience perception of the program has on continuous participation intention and perceived value of the program. Teaching and learning activities of book curation education programs were organized so that practitioners can experience activities for 4 experience element, entertainment experience, educational experience, escapist experience, esthetic experience according to experience economic theory. This study surveyed 195 peoples who participated in the program to measure the effectiveness of the program. As a result of analysis, research hypothesis 1 (the perception of experiences in the book curation education program affects the perceived value of the program) revealed that aesthetic and entertainment experiences were significant, and research hypothesis 2 (the perception of experience in the book curation education program affects the intention to continue participating in the program) showed that all other factors except educational experiences were significant.

노카디옵시스 다손빌레이 ( Nocardiopsis dassonvillei ) 로 부터 분리한 알칼라인 단백질분해 효소의 성질

김미정,정혜신,박순재 ( Mi Jung Kim,Hye Shin Chung,Soon Jae Park ) 생화학분자생물학회 1993 BMB Reports Vol.26 No.1

We have purified a novel alkaline protease from actinomycete Nocardiopsis dassonvillei, ATCC 21944, using conventional chromatographic methods and an ion-exchange HPLC at the final stage. SDS-PAGE of purified enzyme showed that the enzyme is homogeneous, and the apparent molecular weight is 33,500 daltons. Isoelectricfocusing indicates its pI is around 6.3. The enzyme is inhibited by serine protease inhibitors such as phenylmethylsulfonyl fluoride and chymostatin. Temperature-dependent activity profile of the protease indicates that it is thermally stable and retains 70% of the activity at 65℃ compared to the maximum activity shown at 55℃. It also appears to be highly alkalophilic, maintaining almost full activity at pH 11.

2형 당뇨병환자의 만성 치주염 치은조직에서 골흡수 인자의 발현 양상 비교

김미정,류상호,박진우,서조영,이재목,Kim, Mi-Jung,Ryu, Sang-Ho,Park, Jin-Woo,Suh, Jo-Young,Lee, Jae-Mok 대한치주과학회 2007 Journal of Periodontal & Implant Science Vol.37 No.4

Purpose: The purposes of this study were to compare and quantify the expression of MMP-3, $PGE_2$ and IL-6 in the gingival tissues of patients with $type_2$ diabetes mellitus and healthy adults with chronic periodontitis. Material and methods: Gingival tissue samples were obtained during periodontal surgery or tooth extraction. According to the patient's systemic condition & clinical criteria of gingiva, each gingival sample was devided into three groups. Group 1(n=8) is clinically healthy gingiva without bleeding and no evidence of bone resorption or periodontal pockets, obtained from systemically healthy 8 patients. Group 2(n=8) is inflamed gingiva from patients with chronic periodontitis. Group 3(n=8) is inflamed gingiva from patients with chronic periodontitis associated with type 2 DM. Tissue samples were prepared and analyzed by Westernblotting. The quantification of MMP-3, $PGE_2$ and IL-6 were performed using a densitometer and statistically analyzed by one-way ANOVA followed by Tukey test. Results: 1. The expression levels of MMP-3 were shown highest in group 3 compared to group 1 and 2, and It showed increasing tendency in group 2 and 3. 2. The expressions of $PGE_2$ and IL-6 were shown increasing tendency in group 2 and 3, and It was highest in group 3. 3. As expressions of MMP-3 were increased, $PGE_2$ and IL-6 expressions showed increasing tendency in group 3 than group1 and 2, although there were no proportional relationship. Conclusion: This study demonstrated that the expression levels of MMP-3, $PGE_2$ and IL-6 will be inflammatory markers of periodonta linflamed tissue and DM. It can be assumed that MMP-3 affect to expressions of $PGE_2$ and IL-6 in progression of periodontal inflammation with alveolar bone resorption to type 2 DM.

영아에서 경련을 동반한 저칼슘혈증에 관한 연구

김미정,고철우,구자훈,Kim Mi-Jung,Ko Cheol-Woo,Koo Ja-Hoon 대한소아신장학회 1998 Childhood kidney diseases Vol.2 No.1

목적 : 최근 6개월 이하의 영아에서 저칼슘혈증의 임상 경험의 예가 증가하여 이의 원인, 증세, 치료 및 임상 경과를 알아보기 위하여 본 연구를 시행하였다. 방법 : 1994년 2월 부터 1991년 4월까지 경북대학교 병원 소아과에 경련을 주소로 내원하였던 환아 중 그 원인이 저칼슘혈증으로 확인되었던 11예를 대상으로 하였다. 이들은 모두 6개월 이하였으며 평균 $2.2{\pm}1.1$개월이었다. 이들 환아의 병력지를 통하여 후향적으로 각종 검사를 분석하였다. 결과 : 이 환아들의 저칼슘혈증의 원인으로는 비타민 D 결핍이 8예였고, 무기인의 과다한 섭취가 3예였다. 경련의 양상은 전신성 간-근대성이 9예였고 부분 근대성이 2례였다. 경련의 지속시간은 30초에서 20분까지 다양하였으며, 경련의 횟수는 평균 6.5회였다. $Bonky^{(R)}$, 칼슘 단독 또는 병합 요법 후 혈청 칼슘은 치료 전 $6.3{\pm}0.9$ mg/dL서 치료 후 $9.9{\pm}1.7$ mg/dL로 통계학적으로 의미있게 증가하였고(P=0.0008), 혈청 ALP는 치료 전 $1,418{\pm}864$ U/L에서 치료후 $772{\pm}503$ UL로 통계학적으로 의미있게 감소하였다(P=0.0112). 입원 당시 iPTH은 $176.7{\pm}129$ pg/mL로 증가되어 있었고 3명의 환아에서 치료 이후 추후 검사상 정상 범위로 회복 되었다. 모든 환아에서 치료 전$25(OH)D_3$는 감소되어 있었으며 평균 $3.9{\pm}2.7$ ng/mL였고, 치료 후 1예에서 정상으로 회복되었다. $1,25(OH)_{2}D_{3}$는 6예 중 2예에서 감소되어 있었다. 결론 : 최근 비타민 D가 보강된 것으로 알려진 조제 분유 영양아에서 발생된 경련을 동반한 저칼슘혈증의 원인은 상당수에서 비타민 D 결핍이었으며 $1,25(OH)_{2}D_{3}$의 단기간 투여로 성공적으로 치료되었으며, 조제 분유 영양아에서도 저칼슘혈증의 원인으로 비타민 D 결핍을 반드시 생각해야 한다고 사료 된다. Purpose : Hypocalcemia is one of the major causes of convulsion in infants. The causes of hypocalcemia are hypoparathyroidism, deficiency and metabolic abnormalities of vitamin D, or increased uptake of inorganic phosphorous, etc. We analyzed the causes, symptoms and signs, treatment, and clinical courses of hypocalcemia as, recently, there were many clinical experiences of hypocalcemic infants under age of 6 months in the department of pediatrics, Kyungpook University Hospital. Objects and Methods : The authors observed 11 infants with hypocalcemia who had been admitted to the department of pediatrics, Kyungpook University Hospital, during the period of February 1992 to April 1997. Various clinical and laboratory data concerning causes, clinical courses and treatment of hypocalcemia were analyzed retrospectively Results : (1) The sex incidence revealed male predominance with male to female ratio 4.5 : 1. The mean age at onset of symptoms was $2.2{\pm}1.1$ months old. (2) The causes of hypocalcemia were vitamin D deficiency in 8 cases and excessive inorganic phosphate intake in 3 cases. (3) All eleven patients manifestated convulsion which was generalized tonic-clonic in 9, and focal clonic in 2 cases. (4) Serum calcium concentrarion increased from $6.3{\pm}0.9$ mg/dL to $9.9{\pm}1.7$ mg/dL after therapy of $1,25(OH)_{2}D_{3}$ with or without calcium(P=0.0008), and serum ALP concentration decreased from $1,418{\pm}864$ U/L to $772{\pm}503$ U/L (P=0.0112). Serum iPTH levels were high in all 11 patients initially. All showed decreased $25(OH)D_3$ levels initially. (5) All patients were treated successfully with $1,25(OH)_{2}D_{3}$ and/or calcium supplement. Conclusions : Vitamin D deficiency should be considered as one of the causes of hypocalcemia even in formula(known as vitamin fortified) feeding infants. Fortunately, they were successfully treated with $1,25(OH)_{2}D_{3}$.

밀폐유도용해로 제조한 CoSb_3-yTe_y의 열전특성

김미정,심우섭,어순철,김일호,Kim, Mi-Jung,Shim, Woo-Seop,Ur, Soon-Chul,Kim, Il-Ho 한국재료학회 2006 한국재료학회지 Vol.16 No.7

Te-doped $CoSb_3$ was prepared by the encapsulated induction melting, and its doping effects on the thermoelectric properties were investigated. Single phase ${\delta}-CoSb_3$ was successfully obtained by the subsequent annealing at 773 K for 24 hrs. Tellurium atoms acted as electron donors by substituting antimony atoms. Thermoelectric properties were remarkably improved by the appropriate doping. Dimensionless figure of merit was obtained to be 0.83 at 700K for the $CoSb_{2.8}Te_{0.2}$ specimen.