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Clinicopathologic Analysis of Pituitary Adenoma - A Single Institute Experience
조화진,김하나,곽윤진,서정욱,백선하,손철호,윤정민,김다스란,Peter Kang,Peom Park,박성혜 대한의학회 2014 Journal of Korean medical science Vol.29 No.3
Pituitary adenoma (PA) is a common benign neuroendocrine tumor; however, theincidence and proportion of hormone-producing PAs in Korean patients remain unknown. Authors analyzed 506 surgically resected and pathologically proven pituitary lesions of theSeoul National University Hospital from 2006 to 2011. The lesions were categorized as: PAs(n = 422, 83.4%), Rathke’s cleft cysts (RCCs) (n = 54, 10.6%), inflammatory lesions (n = 8,1.6%), meningiomas (n = 4), craniopharyngiomas (n = 4), granular cell tumors (n = 1),metastatic renal cell carcinomas (n = 2), germinomas (n = 1), ependymomas (n = 1), andunsatisfactory specimens (n = 9, 1.8%). PAs were slightly more prevalent in women (M:F = 1:1.17) with a mean age of 48.8 yr (9-80 yr). Immunohistochemical analysis revealedthat prolactin-producing PAs (16.6%) and growth hormone-producing adenomas (9.2%)were the most common functional PAs. Plurihormonal PAs and nonfunctioning (null cell)adenomas were found in 14.9% and 42.4% of patients with PAs, respectively. Therecurrence rate of PAs was 11.1%, but nearly 0% for the remaining benign lesions such asRCCs. 25.4% of patients with PAs were treated by gamma-knife after surgery due toresidual tumors or regrowth of residual tumor. In conclusion, the pituitary lesions and theproportions of hormone-producing PAs in Korean patients are similar to those of previousreports except nonfunctioning (null cell) PAs, which are unusually frequent.
작업자 중심의 소음 관리를 위한 USN 기반 모니터링 시스템 가이드라인 제시
윤정민(Yun Jung Min),신유민(Shin Yu Min),김다스란(Kim Dasran),이규환(Lee Gyu Hwan),박범(Park Peom) 대한인간공학회 2010 대한인간공학회 학술대회논문집 Vol.2010 No.10
Changes in the distribution of the Occupational Safety and Health Industry According to the statistics generated, By noise in the workplace and occupational hearing loss accounts for large proportion of disease that is known. The noise in the workplace to the worker is to give the stress, The resulting increase in operating efficiency and reduced safety risk and bring a negative effect. However, awareness of noise problems, despite the current noise measurement of a week for the six months to measure progress and, Workers did not consider the personal characteristics of the workplace caused all the noise is measured. In this study, in order to solve these problems, the measurement of noise exposure and the time to check the dosage is to provide a system by building. Individual is exposed to an accurate measure of the amount of noise exposure, time and place of work, to fair, fair, depending on quantity to measure the total exposure to noise was. The noise monitoring system for the Ubiquitous Sensor Network using a variety of tasks were designed to be used in space.