비선형 회귀분석과 구조방정식을 이용한 지방부 4지 신호교차로의 사고요인분석

오주택,권일,황정원 대한교통학회 2013 대한교통학회지 Vol.31 No.1

사고발생의 주요지점인 신호교차로 교통사고 발생건수는 해마다 증가하고 있어 교통사고를 감소시키기 위한 원인 규명이 매우 필요하다. 국내에서 연구되어진 기존의 교통사고예측 모형들은 대부분 Poisson 모형 등의 비선형 회귀분석을 이용한 사고원인분석이 주를 이루고 있다. 비선형 Econometrics 분석기법들이 사고의 성격을 분석하는데 가장 중요한 통계적 기법이기는 하지만, 도로에서 발생하는 교통사고의 원인분석적 차원에서 접근하면 이런 사고예측모형들만 가지고 사고발생의 설명변수들을 규명하는데 구조적인 한계가 발생한다. 이는 이러한 통계적 방법들이 사고의 예측력을 높이는데 중점을 두고, 이를 위해 소수의 유효한 설명변수들만을 모형식에 포함시키기 때문이다. 따라서 사고에 대해 보다 구체적인 원인규명을 위해서는 비선형회귀분석모형의 개발과 동시에 비선형 Econometrics 분석기법의 단점을 보완하는 또 다른 통계적 노력이 필요하다. 이에 본 연구에서는 Poisson기법을 이용하여 지방부 4지 신호교차로의 사고예측모형을 개발하였고, 동시에 복합적인 인과관계를 증명하는데 다중변수관계를 포괄적으로 측정하여 탐색하는 구조방정식을 이용하여 사고모형을 개발하여 Poisson 모형의 결과값과 비교·분석하였다. Traffic accidents at signalized intersections have been increased annually so that it is required to examine the causation to reduce the accidents. However, the current existing accident models were developed mainly by using non-linear regression models such as Poisson methods. These non-linear regression methods lack to reveal the complicated causation for traffic accidents, though they are the right choice to study randomness and non-linearity of accidents. Therefore, it is required to utilize another statistical method to make up for the lack of the non-linear regression methods. This study developed accident prediction models for 4 legged signalized intersections with Poisson methods and compared them with structural equation models. This study used structural equation methods to reveal the complicated causation of traffic accidents, because the structural equation method has merits to explain more causational factors for accidents than others.

포스타 : 불임 및 생식내분비학 ; 조기난소부전증으로 진단된후 호르몬대체요법후 자연임신된 1예

송희원,권주택,류철희,김종덕 대한산부인과학회 1999 대한산부인과학회 학술대회 Vol.84 No.-

생쥐배아의 냉동보존에 있어서 여러 조건의 평가 - 저속 처리단계와 급속 처리단계, 배양액, 세포기

이승연,권주택,송희원,조윤희,이기숙,류철희,김종덕,Yi, Seung-Yeun,Kwon, Ju-Taek,Song, Hee-Won,Cho, Yun-Hee,Lee, Ky-Sook,Rheu, Cheul-Hee,Kim, Jong-Duk 대한생식의학회 1999 Clinical and Experimental Reproductive Medicine Vol.26 No.2

Cryopreservation is able to store the surplus pre-embryos for freezing and furthermore thawing and transfer in a subsequent cycle. Cryopreserving cells which are maintaining their viability are the very complex process. This study has been carried out in order to find the effects of cryopreservation steps, freezing media and embryonic stages on the rates of viability and development of cryopreserved mouse embryos. Female ICR mice ($6{\sim}8$ weeks old) were induced to superovulate by sequential intraperitoneal injection of 5 IU PMSG and 5 IU hCG 48h apart. Mouse embryos were collected according to its developmental stage after the injection of hCG. Embryos were cryopreserved not only by cryoprotectant step (1 step${\sim}$4 step) but also in a variety of media (HTF, IVF medium, D-PBS) and cell stage. The results were as follows: There is no clear advantage in these freezing media of rapid method, but 4 cell and 8 cell of slow method (2, 3, 4 step) have advantage in D-PBS. The development of embryos according to cell stage become greater in 8 cell stage. In the treatment steps of cryopreservation, the development of embryo to blastocyst was similar among rapid method, but the development of 4 cell and 8 cell embryos to blastocyst according to slow method was better than rapid method.

임신 34주부터 37주사이의 조기양막파수 환자에서 적극적인 처치와 보존적인 처치의 비교

김종현,권주택,황호명,나미옥,엄철,정영주,조성남 대한산부인과학회 2000 Obstetrics & Gynecology Science Vol.43 No.12

목적 : 임신 34주 0일에서 36주 6일 사이의 조기양막파수 환자에서 적극적 치료와 보존적인 처치를 시행했을 때 산모와 신생아의 이환율에 대한 차이에 대해 알아보고자 한다. 연구 방법 : 본 연구에서는 1997년 1월에서 1998년 12월 말까지 만 2년동안 전북대학교병원 산부인과에 입원한 임신 34주 0일부터 36주 6일 사이의 두위의 단태임신 조기양막파수 환자 121명을 prostaglandin E2 질정이나 oxytocin의 투여로 유도분만을 시도한 적극적인 처치 62명과 진통 억제제와 corticosteroid를 사용하지 않고 단순 침상 안정만을 취한 보존적인 처치 59명의 두 군으로 분류하여 조사하였다. 결과 : 산모의 예후와 이환율은 예상대로 입원에서 분만까지의 잠복기와 총 입원기간이 보존적 처치군에서 유의하게 길었으며(P$lt;0.01) 융모양막염은 보존적 처치군에서 적극적인 처치군보다 의의있게 많았다(P$lt;0.05). 신생아 패혈증은 보존적인 처치를 받은 군에서만 3예(5.1%) 나타났으나 통계학적 의의가 없었으며 모두 별다른 후유증 없이 회복하였다. 결론 : 임신 34주 0일 이상의 조기양막파수 환자에서 적극적인 처치로서의 유도분만은 신생아에게도 안전하며 산모와 신생아의 감염 및 합병증을 피할 수 있다. Objective : Our objective was to compare differences in maternal, neonatal morbidity and mortality associated with active versus expectant management of premature rupture of membranes. Methods : Of 121 women with premature rupture of the membranes at 34 weeks 0 days' to 36 weeks 6 days' gestation, the women were allocated with induction and expectant group randomly. A retrospective review was undertaken to compare active management(n=62) with intravaginal prostaglandin E2, oxytocin induction and expectant management(n=59) included hospitalization without the use of tocolytics and corticosteroid. Results : As expected, the latency to the onset of labor and to delivery was significantly prolonged with expectant management(P$lt;0.01). Maternal hospitalization was significantly prolonged with expectant management(P$lt;0.01). The incidence of chorioamnionitis was significantly higher in expectant management group than active management group(p$lt;0.05). Neonatal sepsis was also more common in the expectant group(n=3) than among induction group(n=0), but the difference was not statistically significant. Conclusions : Active management of premature rupture of the membranes at $gt; 34 weeks 0 days' gestation by induction of labor is safe for the neonate and avoids maternal-neonatal infectious complications in our study.

과배란 유도후 자궁강내 인공수정술의 임신율

윤혜정,나미옥,권주택,김종덕 의과학연구소 2000 全北醫大論文集 Vol.24 No.2

자궁경부 세포에서 Hybrid Capture System 을 이용한 High Risk HPV DNA Test 의 임상적 효용성

김관식,오병찬,조성남,권주택,양춘모,장인석,조장철,엄철 대한부인종양 콜포스코피학회 2000 Journal of Gynecologic Oncology Vol.11 No.2

Human papillomavirus(HPV) has implicated in the development of cervical cancer. Several studies has suggested a strong correlation between HPV 16, 18 and cervical intraepithelial neoplasia(CIN). For detecting and typing HPV DNA in cervical tissues, recently the chemiluminescent molecular hybridization assay method has been widely used. This study was performed to determine the usefulness of hybrid capture assay for detecting high-risk HPV in cervical epithelial cells, and to compare the correlation among cervical cytology, biopsy finding and HPV infection, and to determine whether the addition of the hybrid capture assay to cytologic test would improve the ability to identify significant lesions. This study included 267 patients who visited the colposcopic clinic of the department of obstetrics and gynecology, Chonbuk University Hospital from May, 1997 to October 199S. Pap smears hybrid capture assays, and colposcopically directed biopsy were performed concurrently on al1 women. The results obtained were as follow; 1. Using hybrid capture assay, the detection rate of high-risk HPV of all patients was 37.1%(99/267). There was no statistical significance in the detection rate of HPV between the age groups. 2. The false negative rate of Pap Smear was 53.3% and showed significant discrepancies between the cytologic and histologic diagnosis. 3. According to the cytologic diagnosis, the detection rates of high-risk HPV were 7.1% in normal, 25.3% in ASCUS or LSIL, and 61.6% in HSIL. In each cytologic group, the patients who had positive results for high-risk HPV showed higher incidence rate of high grade lesions than those with negative results(P$lt;0.05). 4. According to the histologic diagnosis, the detection rates of high-risk HPV were 0.1% in normal, 11.1% in CIN I, and 72.7% in CIN Ⅱ or CIN Ⅲ. In each histologic group, the patients who had positive results for high-risk HPV showed higher incidence rate of high grade lesions than those with negative results(P$lt;0.05). 5. According to the comparison of histologic diagnos between positive and negative results of high-risk HPV test due to each cytology, there was no statistical significance in the incidence rate of cervical neoplasia, Above results suggest that high-risk HPV test using hybrid capture assay may be a useful method in supplement the pitfalls of cervical cytology. This test might also have prognostic value in the management of patients with CIN.