Spacing 에서 치아크기와 치열궁크기와의 관계에 대한 연구

이동주(Dong Joo Lee),양춘모(Chun Mo Yang) 조선대학교 구강생물학연구소 1989 Oral Biology Research (Oral Biol Res) Vol.13 No.-

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어려운 기관내 삽관이 예상된 환자에서 후두튜브 삽입 경험

임영수,양춘모,양춘우,강포순,권희욱,조춘규 대한마취통증의학회 2007 Korean Journal of Anesthesiology Vol.52 No.4

Airway management is important during general anesthesia. Difficulty with a direct laryngoscopy can be routinely successfully managed using a laryngeal mask airway. However, a laryngeal mask airway may not be suitable for the patients having a small oral cavity volume or narrow interincisor distance. A 19-year-old man, scheduled for right clavicular fracture had no specific underlying medical problems. However, he had difficultly opening his mouth, and was Mallampati class IV. Also, he had difficultly in extending his neck. Airway management was successfully performed using a laryngeal tube instead of a laryngeal mask airway. The patient was successfully managed, without complications, until the end of the surgery.

배란유도제가 생쥐 미성숙난자의 성숙에 미치는 영향 및 여러 배양액내에서 생쥐 2세포기의 배아 발달에 관한 연구

이종진,양춘모,문현창,이호성,이기숙,류철희,김종덕,Lee, Jong-Jin,Yang, Chun-Mo,Moon, Hyun-Chang,Lee, Ho-Seong,Lee, Ky-Sook,Rheu, Cheul-Hee,Kim, Jong-Duk 대한생식의학회 1999 Clinical and Experimental Reproductive Medicine Vol.26 No.2

Purpose of the present study was to find the optimal ovulation induction medicine for the maturation and development of immature oocytes and culture media for 2-cell embryos in the mouse model. ICR female mouse aged 6 to 8 weeks, were stimulated with 5 IU PMSG injection. At 47 to 50 hour post-PMSG injection, ovaries were dissected out and oocytes-cumulus complexes were punctured. The oocyte-cumulus complexes were cultured in media containing various ovulation induction medicine, CC, HMG and Metrodin for 18 hours. Female ICR mice were stimulated with 5 IU PMSG and 48 hours later were injected 5 IU of hCG, then female and male mice were mated. At 48 hour post-hCG injection, oviducts were dissected out and 2-cell embryos were flushed. The 2-cell embryos were cultured in various media, Ham's F-10 media of milli-Q water $(3^{\circ})$, Ham's F-10 media of HPLC (high performance liquid chromatography, Baxter) water, Medicult media, HTF (human tubal fluid) media for 96 hours. The results were as follows. 1. When the oocytes-cumulus complexes were cultured in $10^{-9}{\mu}g/ml{\sim}10^{-8}{\mu}g/ml$ of CC, those were suppressed in meiotic maturation $(28.2{\sim}33.7%)$. Whereas the oocytes-cumulus complexes were cultured in $10^{-7}{\mu}g/ml{\sim}10^{-4}{\mu}g/ml$, these were not effected in meiotic maturation $(54.5{\sim}72.7%)$. 2. When the oocytes-cumulus complexes were cultured in $10^{-4}{\mu}g/ml{\sim}10^{-1}{\mu}g/ml$ of Metrodin, those were suppressed in meiotic maturation $(35.7{\sim}41.5%)$. Meanwhile the oocytes-cumulus complexes were cultured in $10^{-7}{\mu}g/ml{\sim}10^{-5}{\mu}g/ml$, those were not effected in meiotic maturation $(54.2{\sim}70.3%)$. 3. When the oocytes-cumulus complexes were cultured in $10^{-5}{\mu}g/ml{\sim}10^{-4}{\mu}g/ml$ of HMG, those were suppressed in meiotic maturation $(48.2{\sim}50.4%)$. As being cultured in $10^{-7}{\mu}g/ml{\sim}10^{-6}{\mu}g/ml$, increased in meiotic maturation $(75.8{\sim}80.7%)$. 4. When the 2-cell embryos were cultured in Ham's F-10 media of milli-Q water $(3^{\circ})$, Ham's F-10 media of HPLC (high performance liquid chromatograpy, Baxter) water, Medicult media, HTF (human tubal fluid) media, developmental rates to blastocyst and hatching for 96 hour were 50.0%, 45.2%, 71.5% and 95.6%, respectively.

Spacing 에서 치아크기와 치열궁크기와의 關係에 對한 硏究

李東柱,梁瑃模 朝鮮大學校 口腔生物學硏究所 1989 口腔生物學硏究 Vol.13 No.-

This study was undertaken to examine the relationship between tooth size and arch dimension in dental spacing. Two groups of dental casts were selected on the basis of dental spacing. One group, consisting of 38 pairs of dental casts (19 male and 19 female) and cephalometrics, exhibited remarkable dental spacing. A second group, consisting of 40 pairs of dental casts (20 male and 20 female) and cephalometrics, exhibited no spacing. Mean, Standard deviation, t-test of the following parameters were used to compare two groups : individual and collecive mesiodistal tooth diameters, arch width and length, basal arch width and length, SNA, SNB, ItoSN, IMPA, ItoF.P., ItoF.P. The following results were obtained. 1. In the tooth size, male with spacing had generalized smaller teeth and female with spacing had smaller 4 anterior teeth than the normal group. 2. In the arch width and arch length, the spaced group had longer width and length than the normal group but there was only statistical significance in the arch length. 3. In the basal arch width and length, the spaced group had longer width and length than the normal group but there was only statistical significance in the basal arch length. 4. In maxilla, mandible, and anterior tooth position, the difference between the spaced group and the normal group was no sigificance.

자궁경부 세포에서 Hybrid Capture System 을 이용한 High Risk HPV DNA Test 의 임상적 효용성

김관식,오병찬,조성남,권주택,양춘모,장인석,조장철,엄철 대한부인종양 콜포스코피학회 2000 Journal of Gynecologic Oncology Vol.11 No.2

Human papillomavirus(HPV) has implicated in the development of cervical cancer. Several studies has suggested a strong correlation between HPV 16, 18 and cervical intraepithelial neoplasia(CIN). For detecting and typing HPV DNA in cervical tissues, recently the chemiluminescent molecular hybridization assay method has been widely used. This study was performed to determine the usefulness of hybrid capture assay for detecting high-risk HPV in cervical epithelial cells, and to compare the correlation among cervical cytology, biopsy finding and HPV infection, and to determine whether the addition of the hybrid capture assay to cytologic test would improve the ability to identify significant lesions. This study included 267 patients who visited the colposcopic clinic of the department of obstetrics and gynecology, Chonbuk University Hospital from May, 1997 to October 199S. Pap smears hybrid capture assays, and colposcopically directed biopsy were performed concurrently on al1 women. The results obtained were as follow; 1. Using hybrid capture assay, the detection rate of high-risk HPV of all patients was 37.1%(99/267). There was no statistical significance in the detection rate of HPV between the age groups. 2. The false negative rate of Pap Smear was 53.3% and showed significant discrepancies between the cytologic and histologic diagnosis. 3. According to the cytologic diagnosis, the detection rates of high-risk HPV were 7.1% in normal, 25.3% in ASCUS or LSIL, and 61.6% in HSIL. In each cytologic group, the patients who had positive results for high-risk HPV showed higher incidence rate of high grade lesions than those with negative results(P$lt;0.05). 4. According to the histologic diagnosis, the detection rates of high-risk HPV were 0.1% in normal, 11.1% in CIN I, and 72.7% in CIN Ⅱ or CIN Ⅲ. In each histologic group, the patients who had positive results for high-risk HPV showed higher incidence rate of high grade lesions than those with negative results(P$lt;0.05). 5. According to the comparison of histologic diagnos between positive and negative results of high-risk HPV test due to each cytology, there was no statistical significance in the incidence rate of cervical neoplasia, Above results suggest that high-risk HPV test using hybrid capture assay may be a useful method in supplement the pitfalls of cervical cytology. This test might also have prognostic value in the management of patients with CIN.

백서에서 척수의 허혈/재관류 손상시 neuronal Nitric Oxide Synthase(nNOS)의 발현

이광호,권희욱,강포순,조춘규,양춘우,양춘모,박종택 대한마취통증의학회 2007 Korean Journal of Anesthesiology Vol.52 No.4

The aim of this experimental study was to investigate the expression of nNOS following ischemia/reperfusion injury in rat spinal cord. Methods: Spraque-Dawley rats (250-300 gm) were classified into two groups according to experimental methods. Control group (n = 5) received sham operation. Ischemia in experimental group (n = 5) was induced by clamping the abdominal aorta just below the left renal artery and the abdominal aorta just above the aortic bifurcation for 20 minutes followed by 20 minutes reperfusion. The spinal cord was obtained 7 days after operation. The expression of nNOS was examined in gray and white matter with confocal microscope and Image Analyzer. Results: There is no difference in nNOS expression of nNOS between gray and white matter in control group. Comparing to control group, experimental group showed higher levels of nNOS expression (P < 0.05). Conclusions: nNOS expression increased in the rat spinal cord after ischemia/reperfusion injury. We suggest that overproduction of NO may play a role in progressive nerve cell damage.

경자궁경부 융모막 검사와 경복식 융모막 검사의 비교 연구

송희원(Hee Won Song),임승현(Seong Hyun Lim),양춘모(Choon Mo Yang),엄철(Cheul Um),정영주(Young Ju Jeong),류철희(Cheul Hee Rheu) 대한산부인과학회 2000 Obstetrics & Gynecology Science Vol.43 No.10

목적 : 산전 유전 및 염색체 질환을 진단할 수 있는 융모막 검사에는 경자궁경부방법과 경복식방법이 있다. 본 연구에서는 두 방법의 융모막 검사 중 보다 안전하고 효율적인 방법을 알아보고자 실시하였다. 연구방법 : 본 연구에서는 1991년 1월에서 1998년 6월까지 전북대학교병원 산부인과에서 산전진단의 적응증에 해당하는 788명의 임신여성 중 의무기록지 분석이 가능한 633명의 여성을 대상으로 하였고 이중 490명은 경자궁경부 융모막 검사를 143명은 경복식 융모막검사를 실시받았다. 임신 손실은 재태 28주까지로 정의하였고 임신 예후는 후향적으로 의무기록지를 분석하였다. 전 대상 환자는 동일 시술자가 재태 9~12주 사이에 시술하였으며 두 방법의 융모막 검사 중 보다 안전하고 효율적인 방법을 알고자 임신손실율, 일차 시술성공율, 합병증 등을 비교 하였다. 결과 : 표본 채취 기구의 1회 삽입 후 표본을 얻는데 경자궁경부 방법에서는 88%, 경복식 방법에서는 94.4%의 성공률을 보였다(P<0.05). 시술 후 염색체 검사상 정상이면서 임신 28주까지의 태아손실율은 경자궁경부방법이 경복식방법보다 높았다(4.9%, 3.5%). 시술 후 합병증으로는 융모막하혈종, 양수유출, 질출혈, 융모양막염등이 나타났고, 그 빈도는 경자궁방법이 경복식보다 높았다(3.9%, 2.8%). 결론 : 임신 제 1기에 유전 및 염색체 질환을 진단하는데 경복식 융모막 검사가 경자궁경부방법에 비해 시술이 용이하고 동등한 안전성을 갖는 검사로써 향후 널리 시술될 수 있으리라 생각된다. Objectives : Our purpose was to compare the safety and efficacy of transcervical and transabdominal chorionic villus sampling.Methods : From January 1991 through June 1998, we retrospectively compared transcervical and transabdominal chorionic villus sampling in 633 women. Both CVS procedures were performed between 9 and 12 weeks of gestation by single operator. Both groups were followed to determine the outcome of pregnancy and the rate of spontaneous fetal loss after chorionic villus sampling.Result : Sampling was successful after a single insertion of the sampling instrument in 94.4 percent of the transabdominal procedures and 88 percent of the transcervical procedures(p〈0.05). Among the women with chromosomally normal pregnancies, the rate of spontaneous fetal loss through 28 weeks of pregnancy was 4.9 percent in the transcervical-sampling group and 3.5 percent in the transabdominal-sampling group. The frequency of symptoms and complication after transcervical procedures was slightly higher than transabdominal procedures (3.9%, 2.8%).Conclusion : Transabdominal and transcervical chorionic villus sampling appear to be equally safe procedures for first-trimester diagnosis of fetal abnormalities.