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      • KCI등재

        잠재성 유두상 갑상선암에서 원발종양의 크기에 따른 공격성 정도 분석

        박해린(Hai-Lin Park),곽진영(Jin Young Kwak),강석선(Seok Seon Kang),김도연(Do Youn Kim),강형곤(Hyung Gon Kang),심정연(Jung Yeon Shim),김유리(Yoori Kim),박원근(Won Kun Park),최영길(Young Gil Choi) 대한외과학회 2007 Annals of Surgical Treatment and Research(ASRT) Vol.73 No.6

        Purpose: Occult papillary thyroid carcinomas (OPC) are defined as tumors measuring <15 ㎜. These tumors are believed to be a less aggressive subset of papillary cancers. They generally behave more like benign lesions and are often more conservatively treated. However, it is unclear if a cancer 1.0 to 1.5 ㎝ in diameter will have a similar favorable clinical behavior as tumors <1.0 ㎝ (micropapillary thyroid carcinoma). Therefore, a retrospective chart review study of patients with OPC in order was carried out in order to answer this question and characterize the biology and optimal treatment for OPCs. Methods: From October 2001 to January 2007, Among the impalpable thyroid nodules detected incidentally during screening examinations, 260 patients underwent surgery for occult papillary thyroid cancer (OPC) at Kangnam Cha University hospital. The data from these patients was analyzed retrospectively. The mean follow up period was 25.6 ± 14.5 (max:63, min:1) months. Results: The mean age of these patients was 42.8 years, and 233 (89.5%) were female. 46.2% of patients underwent a total or neartotal thyroidectomy, and 54.6% underwent a central lymph node dissection. Of the 260 patients, 55 (21.2%) had lymph node metastases. The OPC presented with signs of aggressiveness including multifocality (34.2%), bilaterality (17.7%), capsular invasion (52.7%), and lymph node metastases (21.2%). A progressively increasing frequency of the signs of tumor aggressiveness was observed with increasing tumor size at presentation. LN metastases were associated with the tumor size (P=0.0063), extracapsular invasion (P=0.0015) and multfocallity (P=0.0020). However, there was no association with age and gender. With a follow-up of up to 63 months, 3 patients had a local recurrence (0.014%). No patients currently have active disease and no patients with OPC died during this period. Conclusion: In OPC patients, there is a progressively increasing frequency of the signs of tumor aggressiveness with increasing tumor size. Moreover, a small size itself cannot guarantee low risk and low recurrence rate. The prevalence of LN metastases and extracapsular invasion were higher in those with a tumor size >0.5 ㎝. A near-total or total thyroidectomy with a central lymph node dissection is the preferred treatment. The early detection and treatment of OPC might be warranted through the routine use of thyroid USG and USG-guided FNA.

      • 초등학교 고학년이 지각한 부모의 자율성지지가 아동의 행복감에 미치는 영향에서 그릿과 자아존중감의 매개효과

        박소연 ( Park So-youn ),신민진 ( Shin Min-jin ),곽진영 ( Kwak Jin-young ) 한국미술심리치료연구학회 2021 미술심리치료연구 Vol.1 No.1

        본 연구는 초등학교 고학년이 지각한 부모의 자율성 지지가 아동의 행복감에 미치는 영향에서 그릿과 자아존중감이 매개하는지를 검증하였다. 본 연구는 한국청소년정책연구원에서 실행한. ‘한국아동ㆍ청소년 패널조사 2018(The Korean Children and Youth Panel Survey 2018, KCYPS2018)’자료 중 초등학교 4학년 패널 2차년도(2019) 데이터인 초등학교 5학년 총2,437명을 대상으로 하였다. 그 결과 첫째, 아동이 지각한 부모의 양육태도 중 자율성지지는 그릿과 자아존중감에 정적으로 유의하였고, 행복감에는 영향력이 유의하지 않았다. 둘째, 자율성 지지와 행복감 사이에 그릿이 완전매개효과를 보였고, 자율성 지지와 행복감 사이에서 자아존중감이 완전매개효과를 나타냈다. 셋째, 자율성 지지와 행복감 사이에 그릿과 자아존중감은 순차적으로 매개하여 순차적 매개효과를 확인하였다. 본 연구는 아동의 행복감을 향상하기 위해 부모의 자율성지지, 그릿과 자아존중감의 중요함을 밝힌 것으로 아동의 행복감 증진 개입에 있어 기초자료로 활용될 수 있다. The purpose of this study was to examine the mediating effects of children’s grit and self-esteem in the relationship between parental autonomy support and children’s happiness. The participant sample was derived from the Korean Child and Youth Panel Survey 2018(KCYPS 2018), and the data of 2,437 children was analyzed. The results of this study are as follows. First, parental autonomy support had a significant effect on grit and self-esteem. But parental autonomy support had no significant effect on children’s happiness. Second, grit was a statistically significant partial mediator between parental autonomy and happiness. self-esteem was a statistically significant partial mediator between parental autonomy and happiness. Third, there was a sequentially dual mediation effect among grit and self-esteem. This study can be used as a standard for future development of intervention to enhance children’s happiness.

      • KCI등재후보

        신장 이식 96 예에 대한 임상적 고찰

        노임환(Im Hwan Roe),고윤석(Youn Suck Koh),안정경(Jung Kyung Ahn),박찬현(Chan Hyun Park),강종명(Chong Myung Kang),박한철(Han Chul Park),곽진영(Jin Young Kwag),원치규(Chi Kyu Won) 대한내과학회 1988 대한내과학회지 Vol.35 No.2

        N/A We have performed 96 renal transplantations in Hanyang University Hospital since Apri11978. We have analyzed the complications and outcome of these patients in connection with the tissue types and other factors. The results are as follows; 1) The mean age of recipients was 34.4 years. They were most commonly in the 3rd and 4th decades. The male to female ratio was 4.3:l. 2) Among 96 patients, 74 patients received kidneys from living related donors, while 11 patients received donations from living unrelated donors. Eleven cases were cadaver transplantations. Of living related donors, mothers donated in 35 cases (36.5%) and siblings donated in 21 cases (21.9%). All of the cadaver donors were men. 3) HLA typing and cross matching were performed in 56 cases. The grade of the match was defined by the number of shared antigens between donor and recipient. Twenty-seven patients were matched for two antigens. Twelve patients were matched for one antigen, while 12 patients were matched for 3 antigens. Six patients were HLA identical. A mixed lymphoeyte culture was done in 55 patients of there. 33 patients were low responders, who showed less than 55% relative response, 6 patients were high responders (over 100% response), and 16 patients belonged to intermediate group. 4) The recovery rate from acute rejection was 56.5% in living related transplantation patients (sibling; 57.8%, parent and child; 55.1%). In living unrelated transplantation patients, the recovery rate was 50.0%, and it was 42.8% in cadaver transplantation patients. The recovery rate of acute rejection was varied among the different HLA match grades; 62.5% for the group with one antigen matched, 67.0% for two antigens matched, and 100% for four antigens matched. Of low MLC responders, 72% recovered from acute rejection; the higher the relative response, the lower the recovery rates. 5) The Seventy-two of 96 cases were complicated by infertion, mainly pneumonia, fungal infection. The sixty nine of 96 cases were complicated by nonifectious causes, suchas acute tubular necrosis, avascular necrosis of bone, cataract, glaucoma, peptic ulcer and diabetes. 6) The overall mortality rate was 26.0%. During the period of 1978 through 1982, mortality was higher (80%) than that of the period of 1983 through 1987 (20%). The major cause of death before 1982 was infection, The major cause of death after 1983 were hepatic failure and pneumonia. 7) Patients with hepatitis B antigenmia did poorly. Four patients died of hepatic failure, and two patients lost graft. One patient became cirrhotic, 8) The overall patient survival rate was 84.8% at one year and 72.4% at 5 years. The graft survival rate was 81.3% at 1 year and 48.8% at 5 years resply. 8-1) The patient and graft survival rate for living related transplantation patients was 87.0%/82.6% at 1 year and 76.0%/46.7% at 5 years respoectively. The outcome was much better for transplantation between siblings than for parent-child combinations. 8-2) The patient and graft survival rate at 2 years according to HLA match was as follows; 88.9%/81.5% for the group with 2 antigens matched, 88.3%/75.0% for 3 antigens matched, and 100%/83.3% for 4 antigens matched. 8-3) The patient and graft survival rate at 2 years according to MLC was as follows; 96.7%/84.9% in low responders, 93.7%/74.0% in intermediate responders and 31.8%/31.8% in high responders, 8-4) The patient and graft survival rate was compared in patients using different immunosuppressives. Patients with imuran showed 87.0%/85.6% at 6 months and 85.5%/79.8% at 1 year respectively. Patients with cyclosporine showed 91.7%/91.7% at 6 months and 91.7% /86.6% at 1 year. 8-5) Regarding the effect of DST, patients who had not received a transfusion showed a patient and graft survival rate of 77.9%/68.0% at 2 years. Transfused patients did much better, showing survival rate of 96.5 %/84.0% at 2 years. Thus we conclude that MLC and DST greatly influence the survival rate after renal transplantat

      • KCI등재
      • KCI등재후보
      • KCI등재

        류마티스성 관절염 환자에서 발생한 대퇴천동맥의 동맥류파열 1예

        임시연,권오정,이홍기,이광수,곽진영 대한혈관외과학회 2002 Vascular Specialist International Vol.18 No.2

        Isolated true atherosclerotic aneurysm of the distal superficial femoral artery is rare disease. We experienced a case of distal superficial femoral artery aneurysm not associated with dilatation of the common femoral or popliteal artery. True arterial aneurysms are attributed to the weakening of the arterial wall due to atherosclerosis. True superficial femoral artery aneurysms were predominantly founded in elderly men and used to be diagnosed by ultrasonography, CT or angiogram. We report a case of distal superficial femoral arterial aneurysmal rupture in elderly woman who has a rheumatoid athritis and diagnosed by ultrasonography. We performed aneurysmal excision and interposition graft with PTFE.

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