The Effects of Dokhwalgisaeng-tang against Disuse Muscle Atrophy in Gastrocnemius of Rats

공한미,이윤규,이봉효,김재수,이현종 대한침구의학회 2018 대한침구의학회지 Vol.24 No.3

Background: The purpose of this study was to examine the effect of Dokhwalgisaeng-tang on immobilizationinduced muscle atrophy. Methods: Twenty young male Sprague-Dawley rats were divided into 2 groups. The rats in Dokhwalgisaengtang group were orally administered Dokhwalgisaeng-tang water extract, and the rats in the control group were given saline only. Hind limb immobilization was performed with casting tape to keep the left ankle joint in a fully extended position. No intervention was performed on the right leg which was used as an intact region. After 2 weeks of immobilization, all animals were sacrificed, and the gastrocnemius muscle was dissected from both legs and weighed. The morphology of the right and the left gastrocnemius muscle in both the Dokhwalgisaeng-tang and the control group was assessed by hematoxylin and eosin staining. The muscle cross sectional area was examined by image analysis (Axiovision LE software). In addition, immunohistochemical staining was carried out using the free-floating method, and the number of apoptotic related proteins were counted (anti-BAX, anti-Bcl-2). Results: Dokhwalgisaeng-tang showed a significant protective effect against the reduction of the left gastrocnemius muscle (weight and muscle cross sectional area) compared with the control group. Moreover, the treatment with Dokhwalgisaeng-tang significantly reduced protein expression of BAX and increased protein expression of Bcl-2 in the gastrocnemius muscle compared with the control group. Conclusion: Dokhwalgisaeng-tang showed protective effects against disuse muscle atrophy, potentially through altered BAX and Bcl-2 protein expression in the gastrocnemius muscle.

만성 경항통(목부위 통증)의 도침요법, 진통제, 복합치료의 효능 및 안전성 연구

공한미 ( Han Mi Gong ),전승아 ( Seungah Jun ),정연중 ( Yeon-joong Chung ),김주란 ( Ju-ran Kim ),이정희 ( Jung Hee Lee ),이현종 ( Hyun-jong Lee ),박정아 ( Chung A Park ),김재수 ( Jae Soo Kim ) 경락경혈학회 2020 Korean Journal of Acupuncture Vol.37 No.1

Objectives : We investigated the efficacy and safety of miniscalpel acupuncture (MA) treatment combined with non-steroidal anti-inflammatory drugs (NSAIDs) for chronic neck pain (CNP) in an assessor-blinded randomized controlled pilot trial to establish a basis for larger-scale randomized controlled studies on this subject. Methods : Participants (n=36) were recruited and randomly allocated to the MA group, NSAIDs and combined treatment group. The MA group received MA three times over three weeks. The NSAIDs group was administered orally with zaltoprofen 80mg t.i.d. over three weeks. The combined treatment group received MA and zaltoprofen in the same manner as MA and NSAIDs groups. The primary outcome was pain as assessed by a visual analogue scale (VAS) and the secondary outcomes were assessed using the Neck Disability index (NDI), EuroQol 5-dimension questionnaire (EQ-5D), and Patients’ Global Impression of Change scale (PGIC). Assessments were made at week 0 (baseline), 1, 2, 3 (primary end point) during treatment and at week 7 (4 weeks after the end of treatment). Results : 35 participants completed the study. No serious adverse event occurred and blood test results were within normal limits. The improvement of VAS and NDI was significantly greater in combined and MA group than that in NSAIDs group (p<0.017). The combined group showed better outcomes in EQ-5D at visit 2 and 5, in PGIC at visit 4 than the NSAIDs group (p<0.017). No significant differences were found between combined and MA group. Conclusions : Our results suggest that both combined and MA group can be more effective in improving pain control than NSAIDs group. A large-scale clinical study is warranted to further clarify these findings.

CS, V 약침치료를 병행한 대상포진 환자 치험 1례

공한미 ( Han-mi Gong ),전승아 ( Seung-ah Jun ),이현종 ( Hyun-jong Lee ),김재수 ( Jae-soo Kim ) 대한면역약침학회 2016 대한면역약침학회지 Vol.5 No.1

Objectives : This study is to show the clinical effect of additional CS, V Pharmacopuncture on Herpes Zoster patients. Methods : The patient was treated using CS, V Pharmacopuncture, and other treatments including acupuncture and herbal medicine. The effect of treatment is measured by verbal rating scale (VRS), neuropathic pain scale (NPS). Results : After treatment, the VRS grade is changed from 10 to 2. On the NPS, all contents gradually reduced. Consequently, the patient``s quality of life is improved. Conclusions : These results suggest that CS, V Pharmacopuncture might be a possible therapeutic options for pain induced by Herpes Zoster.

A Case Report of Femoral Neck Fracture in an Elderly Patient Managed by Non-operative Korean Medical Treatment : 42 Months Follow-up

김주란,공한미,전승아,이정희,이봉효,이현종,김재수 대한침구의학회 2018 대한침구의학회지 Vol.35 No.4

This report showed the clinical outcome of an elderly patient with a femoral neck fracture who was treated non-operatively with Korean medical treatment. The patient had acupuncture, herbal medication, moxibustion, and participated in physical rehabilitation for 3 months. The effects of Korean medical treatment were measured every 2 weeks using the numeric rating scale (NRS) and the Harris hip score (HHS). After treatments, the NRS score for hip pain decreased from 8 to 2, and the HHS increased from 0 to 43. A 42-month follow-up showed the patient’s NRS score was 0 and the HHS was 61. Furthermore, an X-ray showed complete union of the femoral neck fracture with no suspicion of avascular necrosis. These results suggest that Korean medical treatment can effectively reduce pain and aid rehabilitation in patient with femoral neck fractures with no surgery, resulting in complete union of the fracture.

The Effects of Miniscalpel Acupuncture on Cervicogenic Headache: A report of three cases

전승아,이정희,공한미,정연중,김주란,박정아,최성훈,이건목,이현종,김재수 대한침구의학회 2017 대한침구의학회지 Vol.25 No.1

Objectives : This study examined the effects of miniscalpel acupuncture (MA) in three patients with cervicogenic headache. Methods : Patients were treated with MA, which was performed once per week for three weeks. A headache score, visual analogue scale (VAS), and neck disability index (NDI) were used for the evaluation of treatment effects. Results : In cases 1, 2, and 3, the headache score decreased from 4 to 1, 3 to 0, and 3 to 1, respectively. The VAS score decreased from 8.5 to 1.9, 5 to 0.4, and 5.3 to 2 in cases 1, 2, and 3, respectively. The NDI score decreased from 28 to 4, 50 to 4, and 38 to 16 in cases 1, 2, and 3, respectively. Conclusion : MA appears to be effective for the treatment of cervicogenic headache. Further data should be collected and a comparative study using other treatment methods should be performed.

Miniscalpel acupuncture points of the cervical region: A review

김주란,이정희,공한미,전승아,정연중,박정아,최성훈,이건목,이현종,김재수 대한침구의학회 2017 대한침구의학회지 Vol.34 No.3

Objectives : We conducted a literature search to identify trends with respect to miniscalpel acupuncture points (MAPs) of the cervical region with the aim of providing guidance regarding miniscalpel acupuncture (MA) in the cervical region. Methods : We searched 2 overseas sites (PubMed and Google Scholar) and 5 domestic sites (NDSL, RISS, KISS, OASIS and Korean Traditional Knowledge Portal) for clinical trials of MA of the cervical region. The search terms used were “acupotomy or miniscalpel acupuncture or miniscalpel” and “cervical.” Of 73 studies found, 11 were included in this review, 6 of which presented exact MAPs. Owing to the lack of data, we refer to 1 Korean and 4 Chinese articles to analyze the exact location and meaning of the MAPs used in the published studies and to propose other clinically applicable MAPs. Results : We identified 10 of the most commonly used MAPs in the published studies, including those located below the external occipital protuberance, 2-2.5 cm both side down of the external occipital protuberance, 4.5-5 cm both side down of the external occipital protuberance and C3-7 spinous process. Furthermore, we proposed 13 additional MAPs that can be used clinically. Conclusion : We hope that this study will form a basis for the development of MA and hope to improve the safety and reproducibility in future MA studies of the cervical region.

Efficacy and Safety of Miniscalpel Acupuncture on Knee Osteoarthritis - A randomized controlled pilot trial -

정승아,이정희,공한미,최성훈,황보민,강미숙,이건목,이현종,김재수 대한약침학회 2018 Journal of pharmacopuncture Vol.21 No.3

Objectives: We investigated the efficacy and safety of miniscalpel acupuncture (MA) for knee osteoarthritis (KOA) in an assessor-blinded randomized controlled pilot trial; this would provide information for a large-scale randomized controlled trial. Methods: Participants (n = 24) were recruited and randomly allocated to the MA group (experimental) or acupuncture group (control). The MA group received treatment once a week for 3 weeks (total of 3 treatments), while the acupuncture group received treatment two times per week for 3 weeks (total of 6 treatments). The primary outcome was pain as assessed by a visual analogue scale (VAS). The secondary outcomes (intensity of current pain, stiffness, and physical function) were assessed using the short-form McGill Pain Questionnaire (SF-MPQ) and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Assessments were performed at baseline, 1, 2, and 3 during treatment and at week 5 (2 weeks after the end of treatment). Results: Of the 24 participants, 23 completed the study. Both groups showed significant improvements in VAS, SF-MPQ, and WOMAC. However, there were no significant differences between the MA and acupuncture groups. No serious adverse event occurred and blood test results were within normal limits. Conclusion: Our results suggest that although both MA and acupuncture provide similar effects with regard to pain control in patients with KOA, MA may be more effective in providing pain relief because the same relief was obtained with fewer treatments. A large-scale clinical study is warranted to further clarify these findings.

침치료로 호전되지 않은 퇴행성 슬관절염 환자의 도침치료 1례

박무섭,오세정,이정희,전승아,공한미,최성훈,황보민,이현종,김재수 대한침구의학회 2016 대한침구의학회지 Vol.33 No.3

Miniscalpel Acupuncture Treatment on a Knee Degenerative Osteoarthritis Patient, Who does not Responded to Acupuncture Treatment※ Mu Seob Park1, Se Jung Oh1, Jung Hee Lee1, Seung Ah Jun1, Han Mi Gong1, Seong Hun Choi2, Min Hwangbo3, Hyun Jong Lee1 and Kim Jae Soo1,* 1Departments of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Daegu Haany University 2Departments of Anatomy and Histology, College of Korean Medicine, Daegu Haany University 3Departments of Oriental Ophthalmology and Otolaryngology and Dermatology, College of Korean Medicine, Daegu Haany University Objectives : This study was done to show the clinical effect of miniscalpel acupuncture treatment on osteoarthritis of the knee which is refractory to acupuncture treatment. Methods : A patient was treated with acupuncture for three weeks, non-treated(wash out period) for two weeks, and treated with miniscalpel acupuncture for three weeks. The effect of treatments were measured with Visual Analogue Scale(VAS), Range of Motion(ROM), Short form McGill pain questionnaire(SF-MPQ), Western Ontario and McMaster Universities Osteoarthritis Index(WOMAC). Results : During the three weeks of acupuncture treatment, VAS, SF-MPQ and WOMAC improved, but after two weeks of the wash out period each score worsened. During the three weeks of miniscalpel acupuncture VAS, SF-MPQ, and WOMAC improved while ROM improved remarkably. Conclusion : These results suggest that miniscalpel acupuncture might be a therapeutic option for knee degenerative osteoarthritis patients who does not responded to acupuncture treatment.

신입간호사 교육 기간 단축에 따른 Preceptor program적용에 관한 연구

김혜숙,김이영,최선숙,한미정,김순희,안영희,공성화,장수련,김미애 대한간호협회 1998 대한간호 Vol.37 No.4

도침술의 진료수가에 대한 문제점과 개선방안

오세정,박무섭,이정희,전승아,공한미,최성훈,황보민,이현종,김재수 대한침구의학회 2016 대한침구의학회지 Vol.33 No.3

Problems and Potential Improvements of National Health Insurance Fees Associated with Miniscalpel Acupuncture※ Se Jung Oh1, Mu Seob Park1, Jung Hee Lee1, Seung Ah Jun1, Han Mi Gong1, Seong Hun Choi2, Min Hwangbo3, Hyun Jong Lee1 and Jae Soo Kim1,* 1Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Daegu Haany University 2Department of Anatomy and Histology, College of Korean Medicine, Daegu Haany University 3Department of Oriental Ophthalmology and Otolaryngology and Dermatology, College of Korean Medicine, Daegu Haany University Objectives : The objective of this study is to discuss problems and potential improvements of national health insurance fees associated with miniscalpel acupuncture according to Korean medical doctors' workload, material cost and degree of risk. Methods : We researched the change of relative value points, national health insurance fees, the acupuncture process, and Korean medicine doctors' workload related to Miniscalpel acupuncture, as compared to general meridian point acupuncture. We also examined material cost by surveying pharmacies, internet shopping malls and medical appliance shops. Results : Relative value point for Miniscalpel acupuncture decreased from 2010 to 2012, and remained the same from 2012 to 2016. National health insurance fees for Miniscalpel acupuncture increased by a small margin annually for rise of equivalent index. There was no reporting on workload related to Miniscalpel acupuncture. Material cost of Miniscalpel acupuncture was 18.2~20.7 times higher than actual cost of procedure. There were few studies examining medical accidents related to Miniscalpel acupuncture, and thus we could not evaluate degree of risk. Conclusion : We suggest revaluating Korean medical doctors' workload related to including Miniscalpel acupuncture, to consider the material costs of Miniscalpel acupuncture, and investigate its degree of risk by researching medical accidents.